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A

Amanda G. Paulovich

Fred Hutchinson Cancer Center
H指数:68
被引数:7.8万

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The DNA-PK inhibitor AZD7648 alone or combined with pegylated liposomal doxorubicin in patients with advanced cancer: results of a first-in-human Phase I/IIa study

DNA-PK抑制剂AZD7648单药或联合聚乙二醇化脂质体多柔比星用于晚期癌症患者：一项首次人体I/IIa期研究的结果

BRITISH JOURNAL OF CANCER
IF6.8
2025-05-170
OA
Yap, Timothy A.; LoRusso, Patricia; Miller, Rowan E.; Kristeleit, Rebecca; Paulovich, Amanda G.; McMorn, Stephen; O'Connor, Lenka Oplustil; Lombardi, Benedetta; Marco-Casanova, Paola; Gangl, Eric T.; Patel, Bharat; O'Connor, Mark J.; Dean, Emma; Zviezdin, Roman; Plummer, Ruth
Characterization of an expanded set of assays for immunomodulatory proteins using targeted mass spectrometry

利用靶向质谱法表征免疫调节蛋白的扩展测定方法集

Scientific Data
IF6.9
2024-06-250
OA
Jeffrey R. Whiteaker; Lei Zhao; Regine M. Schoenherr; Dongqing Huang; Jacob J. Kennedy; Richard G. Ivey; Chenwei Lin; Travis D. Lorentzen; Simona Colantonio; Tessa W. Caceres; Rhonda R. Roberts; Joseph G. Knotts; Joshua J. Reading; Candice D. Perry; Sandra S. Garcia-Buntley; William Bocik; Stephen M. Hewitt; Amanda G. Paulovich
A proteogenomic study of high-grade glioma among adolescents and young adults

青少年和年轻人中高级别神经胶质瘤的蛋白质基因组学研究

CANCER RESEARCH
IF16.6
2024-03-220
PRE
Tignor, Nicole; Koptyra, Mateusz P.; Chowdhury, Shrabanti; Ma, Weiping; Rokita, Jo Lynne; Gritsenko, Marina; Song, Xiaoyu; Marino, Giacomo B.; Deng, Eden Z.; Petralia, Francesca; Krek, Azra; Rykunov, Dmitry; Leprevost, Felipe da Veiga; Hosseini, Noshad; Rathi, Komal S.; Hu, Yingwei; Migliozzi, Simona; Yaron, Tomer; Fu, Weijia; Zhang, Bo; Zhu, Yuankun; Brown, Miguel A.; Whiteaker, Jeffrey R.; Mesri, Mehdi; Robles, Ana I.; Rodland, Karin; Cantley, Lewis C.; Iavarone, Antonio; Aldape, Kenneth; Cieslik, Marcin; Nesvizhskii, Alexey I.; Ippolito, Joseph E.; Rubin, Joshua B.; Paulovich, Amanda G.; Zhang, Hui; Ma'ayan, Avi; Liu, Tao; Storm, Phillip B.; Resnick, Adam C.; Rood, Brian R.; Wang, Pei
Monitoring Both Extended and Tryptic Forms of Stable Isotope-Labeled Standard Peptides Provides an Internal Quality Control of Proteolytic Digestion in Targeted Mass Spectrometry-Based Assays

监测稳定同位素标记的标准肽的扩展形式和胰蛋白酶形式，可在基于质谱的靶向测定中对蛋白水解消化进行内部质量控制

MOLECULAR & CELLULAR PROTEOMICS
IF5.5
2023-09-010
OAAI
Lundeen, Rachel A.; Kennedy, Jacob J.; Murillo, Oscar D.; Ivey, Richard G.; Zhao, Lei; Schoenherr, Regine M.; Hoofnagle, Andrew N.; Wang, Pei; Whiteaker, Jeffrey R.; Paulovich, Amanda G.
Phase I/II results of ceralasertib as monotherapy or in combination with acalabrutinib in high-risk relapsed/refractory chronic lymphocytic leukemia

ceralasertib单药治疗或联合acalabrutinib治疗高危复发/难治性慢性淋巴细胞白血病的I/II期结果

THERAPEUTIC ADVANCES IN HEMATOLOGY
IF3.1
2023-05-302
OAAI
Jurczak, Wojciech; Elmusharaf, Nagah; Fox, Christopher P.; Townsend, William; Paulovich, Amanda G.; Whiteaker, Jeffrey R.; Krantz, Fanny; Wun, Chuan-Chuan; Parr, Graeme; Sharma, Shringi; Munugalavadla, Veerendra; Manwani, Richa; Dean, Emma; Munir, Talha
A multiplexed assay for quantifying immunomodulatory proteins supports correlative studies in immunotherapy clinical trials
FRONTIERS IN ONCOLOGY
IF3.3
2023-05-024
OAAI
Whiteaker, Jeffrey R.; Zhao, Lei; Schoenherr, Regine M.; Huang, Dongqing; Lundeen, Rachel A.; Voytovich, Ulianna; Kennedy, Jacob J.; Ivey, Richard G.; Lin, Chenwei; Murillo, Oscar D.; Lorentzen, Travis D.; Colantonio, Simona; Caceres, Tessa W.; Roberts, Rhonda R.; Knotts, Joseph G.; Reading, Joshua J.; Perry, Candice D.; Richardson, Christopher W.; Garcia-Buntley, Sandra S.; Bocik, William; Hewitt, Stephen M.; Chowdhury, Shrabanti; Vandermeer, Jackie; Smith, Stephen D.; Gopal, Ajay K.; Ramchurren, Nirasha; Fling, Steven P.; Wang, Pei; Paulovich, Amanda G.
Fanconi anemia-isogenic head and neck cancer cell line pairs: A basic and translational science resource
INTERNATIONAL JOURNAL OF CANCER
IF4.7
2023-03-301
OA
Nguyen, Hiep Tai; Tang, Weiliang; Webster, Andrew L. H.; Whiteaker, Jeffrey R. R.; Chandler, Christopher M. M.; Errazquin, Ricardo; Roohollahi, Khashayar; Fritzke, Madeline; Hoskins, Elizabeth E. E.; Jonlin, Erica; Wakefield, Leslie; Sullivan, Lucas B. B.; Chen, Eleanor Y. Y.; Dorsman, Josephine; Brakenhoff, Ruud; Paulovich, Amanda G. G.; Grompe, Markus; Garcia-Escudero, Ramon; Wells, Susanne I. I.; Smogorzewska, Agata; Monnat Jr, Raymond J. J.
Intraventricular B7-H3 CAR T Cells for Diffuse Intrinsic Pontine Glioma: Preliminary First-in-Human Bioactivity and Safety

脑室内B7-H3 CAR T细胞用于弥漫性内源性脑桥胶质瘤: 初步的人类首次生物活性和安全性

CANCER DISCOVERY
IF33.3
2022-10-19120
OAAI
Vitanza, Nicholas A.; Wilson, Ashley L.; Huang, Wenjun; Seidel, Kristy; Brown, Christopher; Gustafson, Joshua A.; Yokoyama, Jason K.; Johnson, Adam J.; Baxter, Blake A.; Koning, Ryan W.; Reid, Aquene N.; Meechan, Michael; Biery, Matthew C.; Myers, Carrie; Rawlings-Rhea, Stephanie D.; Albert, Catherine M.; Browd, Samuel R.; Hauptman, Jason S.; Lee, Amy; Ojemann, Jeffrey G.; Berens, Michael E.; Dun, Matthew D.; Foster, Jessica B.; Crotty, Erin E.; Leary, Sarah E. S.; Cole, Bonnie L.; Perez, Francisco A.; Wright, Jason N.; Orentas, Rimas J.; Chour, Tony; Newell, Evan W.; Whiteaker, Jeffrey R.; Zhao, Lei; Paulovich, Amanda G.; Pinto, Navin; Gust, Juliane; Gardner, Rebecca A.; Jensen, Michael C.; Park, Julie R.
Internal Standard Triggered-Parallel Reaction Monitoring Mass Spectrometry Enables Multiplexed Quantification of Candidate Biomarkers in Plasma
ANALYTICAL CHEMISTRY
IF6.7
2022-06-2911
OAAI
Kennedy, Jacob J.; Whiteaker, Jeffrey R.; Ivey, Richard G.; Burian, Aura; Chowdhury, Shrabanti; Tsai, Chia-Feng; Liu, Tao; Lin, ChenWei; Murillo, Oscar D.; Lundeen, Rachel A.; Jones, Lisa A.; Gafken, Philip R.; Longton, Gary; Rodland, Karin D.; Skates, Steven J.; Landua, John; Wang, Pei; Lewis, Michael T.; Paulovich, Amanda G.
Multiomic analysis identifies CPT1A as a potential therapeutic target in platinum-refractory, high-grade serous ovarian cancer
CELL REPORTS MEDICINE
IF10.6
2021-12-0136
OAAI
Huang, Dongqing; Chowdhury, Shrabanti; Wang, Hong; Savage, Sara R.; Ivey, Richard G.; Kennedy, Jacob J.; Whiteaker, Jeffrey R.; Lin, Chenwei; Hou, Xiaonan; Oberg, Ann L.; Larson, Melissa C.; Eskandari, Najmeh; Delisi, Davide A.; Gentile, Saverio; Huntoon, Catherine J.; Voytovich, Uliana J.; Shire, Zahra J.; Yu, Qing; Gygi, Steven P.; Hoofnagle, Andrew N.; Herbert, Zachary T.; Lorentzen, Travis D.; Calinawan, Anna; Karnitz, Larry M.; Weroha, S. John; Kaufmann, Scott H.; Zhang, Bing; Wang, Pei; Birrer, Michael J.; Paulovich, Amanda G.
Targeted Mass Spectrometry Enables Multiplexed Quantification of Immunomodulatory Proteins in Clinical Biospecimens
FRONTIERS IN IMMUNOLOGY
IF5.9
2021-11-1115
OAAI
Whiteaker, Jeffrey R.; Lundeen, Rachel A.; Zhao, Lei; Schoenherr, Regine M.; Burian, Aura; Huang, Dongqing; Voytovich, Ulianna; Wang, Tao; Kennedy, Jacob J.; Ivey, Richard G.; Lin, Chenwei; Murillo, Oscar D.; Lorentzen, Travis D.; Thiagarajan, Mathangi; Colantonio, Simona; Caceres, Tessa W.; Roberts, Rhonda R.; Knotts, Joseph G.; Reading, Joshua J.; Kaczmarczyk, Jan A.; Richardson, Christopher W.; Garcia-Buntley, Sandra S.; Bocik, William; Hewitt, Stephen M.; Murray, Karen E.; Do, Nhan; Brophy, Mary; Wilz, Stephen W.; Yu, Hongbo; Ajjarapu, Samuel; Boja, Emily; Hiltke, Tara; Rodriguez, Henry; Paulovich, Amanda G.
Comparative analysis of TCR and CAR signaling informs CAR designs with superior antigen sensitivity and in vivo function

TCR和CAR信号的比较分析使CAR设计具有更高的抗原敏感性和体内功能

SCIENCE SIGNALING
IF6.6
2021-08-2481
OA
Salter, Alexander, I; Rajan, Anusha; Kennedy, Jacob J.; Ivey, Richard G.; Shelby, Sarah A.; Leung, Isabel; Templeton, Megan L.; Muhunthan, Vishaka; Voillet, Valentin; Sommermeyer, Daniel; Whiteaker, Jeffrey R.; Gottardo, Raphael; Veatch, Sarah L.; Paulovich, Amanda G.; Riddell, Stanley R.
Targeted mass-spectrometry-based assays enable multiplex quantification of receptor tyrosine kinase, MAP kinase, and AKT signaling

基于靶向质谱的测定可实现受体酪氨酸激酶、MAP激酶和AKT信号的多重定量

CELL REPORTS METHODS
IF4.5
2021-07-018
OAAI
Whiteaker, Jeffrey R.; Sharma, Kanika; Hoffman, Melissa A.; Kuhn, Eric; Zhao, Lei; Cocco, Alexandra R.; Schoenherr, Regine M.; Kennedy, Jacob J.; Voytovich, Ulianna; Lin, Chenwei; Fang, Bin; Bowers, Kiah; Whiteley, Gordon; Colantonio, Simona; Bocik, William; Roberts, Rhonda; Hiltke, Tara; Boja, Emily; Rodriguez, Henry; McCormick, Frank; Holderfield, Matthew; Carr, Steven A.; Koomen, John M.; Paulovich, Amanda G.

研究方向

暂未获取到该数据
J
Jeffrey R. Whiteaker
H 指数:49论文数:123被引数:1.4万
L
Lei Zhao
H 指数:28论文数:71被引数:4,573
J
Jacob J. Kennedy
H 指数:25论文数:64被引数:4,518
C
Chenwei Lin
H 指数:39论文数:143被引数:1.0万
S
Steven A. Carr
H 指数:152论文数:989被引数:9.4万
R
Richard G. Ivey
H 指数:20论文数:59被引数:2,370
P
Pei Wang
H 指数:82论文数:508被引数:3.2万
H
Henry Rodriguez
H 指数:63论文数:221被引数:2.4万
R
Regine M. Schoenherr
H 指数:18论文数:55被引数:1,631
P
Ping Yan
H 指数:31论文数:339被引数:5,993