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W

Wen Zhang

Zhejiang University of Technology

19H指数
99论文数
2.9K被引数
收录论文 51
发表时间
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Fruquintinib plus sintilimab in previously bevacizumab-treated, pMMR/MSS refractory metastatic colorectal cancer: a phase 2 clinical trialfruquintinib 联合 sintilimab 治疗既往接受过 bevacizumab 治疗、pMMR/MSS 难治性转移性结直肠癌：一项 II 期临床研究
errCancer Immunology, Immunotherapy
IF0
err2025-11-20
err0
errOAAI
errWen. Zhang; Cai-Feng. Gong; Jing-Long. Huang; Tian-Yi. Liu; Yong-Kun. Sun; Zhi-Chao. Jiang; Wang. Qu; Lin. Yang; Ying. Xin; Fei-Long. Zhao; Yue-zong. Bai; Ai-Ping. Zhou
err分享
err收藏
Small-Molecule Inhibitors Targeting PD-1/PD-L1 in Colorectal Cancer: Mechanisms, Challenges, and Clinical Prospects靶向PD-1/PD-L1的小分子抑制剂在结直肠癌中的机制、挑战与临床前景
errCHEMMEDCHEM
IF3.4
err2025-11-01
err0
errOAAI
errWang, Jianwei; Yu, Shenwei; Qian, Liang; Wu, Yanling; Zhang, Wen; Awadasseid, Annoor
err分享
err收藏
Antineuroblastoma Activity Evaluation and Mechanism of Novel PD-L1 Small Molecule Inhibitors through Immune and Non-Immune Pathways抗神经母细胞瘤活性的评价及通过免疫和非免疫途径的新型PD-L1小分子抑制剂的机制研究
errACS Pharmacology & Translational Science
IF3.7
err2025-07-07
err0
PREAI
errJianwei Wang; Yongnan Zhou; Zejie Chen; Xiaoyin Zhao; Haoran Xu; Feng Zhang; Awadasseid Annoor; Rui Wang; Caiyun Wu; Hua Zhang; Mengyu Zhu; Wen Zhang
err分享
err收藏
Advances in cancer immunotherapy using small-molecular inhibitors targeting the PD-1/PD-L1 interaction针对PD-1/PD-L1相互作用的癌症免疫治疗中使用小分子抑制剂的研究进展
errBIOORGANIC & MEDICINAL CHEMISTRY
IF3
err2025-06-07
err0
PREAI
errZhang, Feng; Ramar, Sivaramakarthikeyan; Wang, Yu; Xu, Haoran; Zhang, Koutian; Awadasseid, Annoor; Rao, Guowu; Zhang, Wen
err分享
err收藏
Comparative druggability of PD-1/PD-L1 inhibitors (A56, HD10): Cross-species differences in PD-L1 exposure and efficacyPD-1/PD-L1抑制剂（A56，HD10）的比较成药性：PD-L1暴露和疗效的跨物种差异
errBioorganic & Medicinal Chemistry
IF3
err2025-06-03
err0
PREAI
errAnnoor Awadasseid; Rui Wang; Koutian Zhang; Shijia Zhou; Feng Zhang; Zeyun Jin; Wen Zhang
err分享
err收藏
Efficacy and safety of triplet regimen capecitabine, oxaliplatin, and irinotecan (XELOXIRI) as first-line chemotherapy for advanced pancreatic cancer
errBMC CANCER
IF3.4
err2025-03-12
err0
errOAAI
errCao, Bi-Yang; Cao, Qi; Ma, Xiao-Ting; Ou, Kai; Yang, Wen-Wei; Zhang, Le-Tian; Lu, Jing-Yu; Jiang, Zhi-Chao; Zhang, Wen; Zhang, Jie; Wang, Qi; Gao, Li-Zhen; Yang, Lin
err分享
err收藏
Design, synthesis and biological evaluation of novel TMPRSS2-PROTACs with florosubstituted 4-guanidino-N-phenylbenzamide derivative ligands
errBIOORGANIC & MEDICINAL CHEMISTRY
IF3
err2024-12-01
err1
PREAI
errYang, Hao; Xu, Haoran; Lin, Xinxin; Cai, Zengxuan; Xia, Yong; Wang, Yu; Chen, Zejie; Zhang, Koutian; Wu, Yanling; Wang, Jianwei; Awadasseid, Annoor; Zhang, Wen
err分享
err收藏
Design, synthesis, and evaluation of antitumor activity of 2-arylmethox-y-4-(2-fluoromethyl-biphenyl-3-ylmethoxy) benzylamine derivatives as PD-1/PD-l1 inhibitors
errEUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
IF5.9
err2024-10-01
err1
PREAI
errZhang, Feng; Zhang, Hua; Zhou, Shijia; Plewka, Jacek; Wang, Ming; Sun, Shishi; Wu, Caiyun; Yu, Qimeng; Zhu, Mengyu; Awadasseid, Annoor; Wu, Yanling; Magiera-Mularz, Katarzyna; Zhang, Wen
err分享
err收藏
Design, synthesis, anti-tumor activity and mechanism of novel PROTACs as degraders of PD-L1 and inhibitors of PD-1/PD-L1 interaction新型PD-L1降解剂和PD-1/PD-L1相互作用抑制剂的设计、合成、抗肿瘤活性及机制研究
errBIOORGANIC & MEDICINAL CHEMISTRY
IF3
err2024-09-01
err2
PREAI
errZhang, Feng; Yu, Qimeng; Wu, Caiyun; Sun, Shishi; Wang, Yu; Wang, Rui; Chen, Zejie; Zhang, Hua; Xiong, Xuqiong; Awadasseid, Annoor; Rao, Guowu; Zhao, Xiaoyin; Zhang, Wen
err分享
err收藏
Current status of drugs targeting PDGF/PDGFR
errDRUG DISCOVERY TODAY
IF7.5
err2024-07-01
err5
PREAI
errAi, Jing-Yan; Liu, Chen -Fu; Zhang, Wen; Rao, Guo-Wu
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err收藏
The efficacy and safety of short-course radiotherapy followed by sequential chemotherapy and cadonilimab for locally advanced rectal cancer: The preliminary findings of prospective, multicenter phase II trial
errANNALS OF ONCOLOGY
IF65.4
err2024-06-01
err0
PREAI
errFeng, L.; Tang, Y.; Zhang, W.; Xu, T.; Li, H.; Ma, H.; Zhou, H.; Kang, W.; Huang, W.; Zou, S-M.; Chi, Y.; Wang, Y.; Deng, F.; Jiang, L-M.; Hu, C.; Chen, Y.; Jin, J.
err分享
err收藏
Targeting TYK2 for Fighting Diseases: Recent Advance of TYK2 Inhibitors
errCURRENT MEDICINAL CHEMISTRY
IF3.5
err2024-06-01
err0
PREAI
errDu, Si-Shi; Fang, Yu-Qing; Zhang, Wen; Rao, Guo-Wu
err分享
err收藏
Perioperative chemotherapy with docetaxel plus oxaliplatin and S-1 (DOS) versus oxaliplatin plus S-1 (SOX) for the treatment of locally advanced gastric or gastro-esophageal junction adenocarcinoma (MATCH): an open-label, randomized, phase 2 clinical trial多西他赛加奥沙利铂和S-1 (DOS) 与奥沙利铂加S-1 (SOX) 围手术期化疗治疗局部晚期胃或胃食管交界处腺癌 (MATCH): 一项开放标签，随机，2期临床试验
errGASTRIC CANCER
IF5.1
err2024-03-08
err6
errOAAI
errJiang, Zhichao; Xie, Yibin; Zhang, Wen; Du, Chunxia; Zhong, Yuxin; Zhu, Yuelu; Jiang, Liming; Dou, Lizhou; Shao, Kang; Sun, Yongkun; Xue, Qi; Tian, Yantao; Gao, Shugeng; Zhao, Dongbing; Zhou, Aiping
err分享
err收藏
Research Progress in the Clinical Treatment of Familial Hypercholesterolemia
errCURRENT MEDICINAL CHEMISTRY
IF3.5
err2024-03-01
err1
PREAI
errAi, Jing-Yan; Zhao, Peng-Cheng; Zhang, Wen; Rao, Guo-Wu
err分享
err收藏
Recent advances and mechanisms of action of PD-L1 degraders as potential therapeutic agentsPD-L1降解剂作为潜在治疗剂的最新进展和作用机制
errEUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
IF5.9
err2024-03-01
err4
PREAI
errZhang, Feng; Jiang, Ruiya; Sun, Shishi; Wu, Caiyun; Yu, Qimeng; Awadasseid, Annoor; Wang, Jianwei; Zhang, Wen
err分享
err收藏
Small molecule and PROTAC molecule experiments in vitro and in vivo, focusing on mouse PD-L1 and human PD-L1 differences as targets
errBIOMEDICINE & PHARMACOTHERAPY
IF7.5
err2024-03-01
err0
errOAAI
errAwadasseid, Annoor; Wang, Rui; Sun, Shishi; Zhang, Feng; Wu, Yanling; Zhang, Wen
err分享
err收藏
Research Status, Synthesis and Clinical Application of Antiepileptic Drugs
errCURRENT MEDICINAL CHEMISTRY
IF3.5
err2024-02-01
err4
PREAI
errWang, Si-Jie; Zhao, Min-Yan; Zhao, Peng-Cheng; Zhang, Wen; Rao, Guo-Wu
err分享
err收藏
Deep-Learning- and Unmanned Aerial Vehicle-Based Structural Crack Detection in Concrete基于深度学习和无人机的混凝土结构裂缝检测
errBUILDINGS
IF3.1
err2023-12-15
err3
errOAAI
errJin, Tao; Zhang, Wen; Chen, Chunlai; Chen, Bin; Zhuang, Yizhou; Zhang, He
err分享
err收藏
Clinical Application and Synthesis Methods of Deuterated Drugs
errCURRENT MEDICINAL CHEMISTRY
IF3.5
err2023-11-01
err9
PREAI
errXu, Xiao-Liang; Zhang, Wen; Rao, Guo-Wu
err分享
err收藏
Research Progress in Competitive Purine Antagonists
errCURRENT MEDICINAL CHEMISTRY
IF3.5
err2023-10-01
err0
PREAI
errYing, Dan-Xia; Zhao, Peng-Cheng; Zhang, Wen; Rao, Guo-Wu
err分享
err收藏

研究方向

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