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Adam R. Renslo

university of california san francisco

46H指数
208论文数
8.3K被引数
收录论文 108
发表时间
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Dietary cholesterol activates a Ral-dependent pathway driving LDLR turnover膳食胆固醇激活依赖Ral的通路驱动LDLR周转
errNature
IF48.5
err2026-06-24
err0
PREAI
errXue Feng; Shuo Zhang; Yuqi Wang; Twisha Kurlagunda; Allyssa Sit; Priyadarshini Jaishankar; Pusu Yang; Sadatsugu Sakane; Se Yong Park; Churaibhon Wisessaowapak; Kaylee Nguyen; Jamie Yan; Himani Pothulu; Catherine Dinh; Felicia Chu; Yuyao Ren; Bichen Zhang; Patrick Secrest; Linmeng Han; Chao-Wei Hung; Preethi Veeragandham; Yuliya Skorobogatko; Tatiana Kisseleva; Philip L.S.M. Gordts; Adam R. Renslo; Peng Zhao; Amit R. Majithia; Alan R. Saltiel
err分享
err收藏
Repurposing drug screen for the identification of helicase inhibitors from viruses of pandemic concern用于识别来自流行病相关病毒解旋酶抑制剂的药物重用筛选
errSLAS Discovery
IF2.7
err2026-04-29
err0
errOAAI
errNicole L. Inniss; Margarita Rzhetskaya; Ryan P. Kich; Elizabeth Gleason; Taha Y. Taha; Francisco J. Zapatero-Belinchón; Julia Rosecrans; Valentina Pedrero-Classen; Kenneth Huang; Gilles Degotte; Luca Lizzadro; Jason Pattie; Adam R. Renslo; George Minasov; Melanie Ott; Kelly E.R. Bachta; Karla J.F. Satchell; Judd F. Hultquist
err分享
err收藏
Labile iron pool dynamics do not drive ferroptosis in colorectal cancer cells不稳定铁池动态不驱动结直肠癌细胞中的铁死亡
errJournal of Biological Chemistry
IF3.9
err2026-03-10
err0
errOAAI
errVarun Ponnusamy; Deahzana R. Randall; Zheng Hong Lee; Nupur K. Das; Liang Zhao; Kathryn Buscher; Sumeet Solanki; Adam R. Renslo; Peggy P. Hsu; Yatrik M. Shah
err分享
err收藏
Structure-Based Design of Reversible; Quinoline-2(1H)-one Inhibitors of Serine- and Metallo-Carbapenemases基于结构的可逆性喹啉-2(1H)-酮类丝氨酸及金属-碳青霉烯酶抑制剂的分子设计
errACS Omega
IF4.3
err2026-02-26
err0
errOAAI
errLian M. C. Jacobs; Priyadarshini Jaishankar; Jeffrey Zheng; Eric R. Hantz; Isabel Lee; Krishna Narramneni; Nicholas Poore; Nathanial Torres; Jessica K. Jackson; Oriana Williams; Sophie E. Darch; Lindsey N. Shaw; Yu Chen; Adam R. Renslo
err分享
err收藏
Discovery of AVI-6451, a Potent and Selective Inhibitor of the SARS-CoV-2 ADP-Ribosylhydrolase Mac1 with Oral Efficacy In Vivo
errJOURNAL OF MEDICINAL CHEMISTRY
IF6.8
err2025-12-01
err0
PREAI
errJaishankar, Priyadarshini; Correy, Galen J.; Matsui, Yusuke; Togo, Takaya; Rachman, Moira M.; Stevens, Maisie G. V.; Hantz, Eric R.; Zheng, Jeffrey; Diolaiti, Morgan E.; Montano, Mauricio; Taha, Taha Y.; Rosecrans, Julia; Pampel, Julius; Krogan, Nevan J.; Shoichet, Brian K.; Ashworth, Alan; Ott, Melanie; Fraser, James S.; Renslo, Adam R.
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err收藏
The Mac1 ADP-ribosylhydrolase is a therapeutic target for SARS-CoV-2Mac1 ADP-核糖基水解酶是SARS-CoV-2的 therapeutic target。
errELIFE
IF0
err2025-11-19
err1
errOAAI
errSuryawanshi, Rahul K.; Jaishankar, Priyadarshini; Correy, Galen J.; Rachman, Moira M.; O'leary, Patrick C.; Taha, Taha Y.; Matsui, Yusuke; Zapatero-Belinchon, Francisco J.; Mccavitt-Malvido, Maria; Doruk, Yagmur U.; Stevens, Maisie Gv; Diolaiti, Morgan E.; Jogalekar, Manasi P.; Chen, Huadong; Richards, Alicia L.; Kongpracha, Pornparn; Bali, Sofia; Montano, Mauricio; Rosecrans, Julia; Matthay, Michael; Togo, Takaya; Gonciarz, Ryan L.; Gopalkrishnan, Saumya; Neitz, R. Jeffrey; Krogan, Nevan J.; Swaney, Danielle L.; Shoichet, Brian K.; Ott, Melanie; Renslo, Adam R.; Ashworth, Alan; Fraser, James S.
err分享
err收藏
Identifying a next-generation antimalarial trioxolane in a landscape of artemisinin partial resistance在青蒿素部分耐药背景下鉴定下一代抗疟三氧杂环戊烷类药物
errScience Advances
IF12.5
err2025-08-08
err0
errOAAI
errMatthew T. Klope; Poulami Talukder; Brian R. Blank; Sevil Chelebieva; Jun Chen; Shaun D. Fontaine; Ryan L. Gonciarz; Priyadarshini Jaishankar; Grace J. Lee; Jennifer Legac; Vineet Mathur; Avani Narayan; Martin Okitwi; Stephen Orena; Nicholas S. Settineri; Juan A. Tapia; Yoweri Taremwa; Patrick K. Tumwebaze; Aswathy Vinod; Jeremy N. Burrows; Philip J. Rosenthal; Roland A. Cooper; Adam R. Renslo
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err收藏
Blocking C-terminal processing of KRAS4b via a direct covalent attack on the CaaX-box cysteine通过直接共价攻击CaaX盒半胱氨酸来阻断KRAS4b的C末端加工
errPROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
IF9.1
err2025-05-09
err0
errOAAI
errMaciag, Anna E.; Yang, Yue; Sharma, Alok K.; Turner, David M.; Dehart, Caroline J.; Abdelkarim, Hazem; Fan, Lixin; Smith, Brian P.; Kumari, Vandana; Dyba, Marcin; Rigby, Megan; Badillo, Jean A. Castillo; Adams, Lauren; Fornelli, Luca; Fox, Stephen; Brafman, Alla; Turbyville, Thomas; Gillette, William; Messing, Simon; Agamasu, Constance; Wolfe, Andrew L.; Gysin, Stephan; Chan, Albert H.; Simanshu, Dhirendra K.; Esposito, Dominic; Chertov, Oleg; Stephen, Andrew G.; Arkin, Michelle; Renslo, Adam; Kelleher, Neil L.; Gaponenko, Vadim; Lightstone, Felice C.; Nissley, Dwight, V; McCormick, Frank
err分享
err收藏
Structure-based discovery of highly bioavailable, covalent, broad-spectrum coronavirus MPro inhibitors with potent in vivo efficacy基于结构的具有高生物利用度、共价键、广谱冠状病毒MPro抑制剂的发现，并具有强体内效力
errSCIENCE ADVANCES
IF12.5
err2025-04-25
err0
errOAAI
errDetomasi, Tyler C.; Degotte, Gilles; Huang, Sijie; Suryawanshi, Rahul K.; Diallo, Amy; Lizzadro, Luca; Zaptero-Belinchon, Francisco J.; Taha, Taha Y.; Li, Jiapeng; Richards, Alicia L.; Hantz, Eric R.; Alam, Zain; Montano, Mauricio; McCavitt-Malvido, Maria; Gumpena, Rajesh; Partridge, James R.; Correy, Galen J.; Matsui, Yusuke; Charvat, Annemarie F.; Glenn, Isabella S.; Rosecrans, Julia; Revalde, Jezrael L.; Anderson, Dashiell; Hultquist, Judd F.; Arkin, Michelle R.; Neitz, R. Jeffrey; Swaney, Danielle L.; Krogan, Nevan J.; Shoichet, Brian K.; Verba, Kliment A.; Ott, Melanie; Renslo, Adam R.; Craik, Charles S.
err分享
err收藏
Preclinical evaluation of TTR-201, a novel ferrous-iron responsive (FIRE) conjugate of the topoisomerase-I inhibitor exatecan
errEUROPEAN JOURNAL OF CANCER
IF7.1
err2024-10-01
err0
PREAI
errLee, G.; Fontaine, S. D.; Renslo, A. R.; Collisson, E. A.
err分享
err收藏
Ferrous Iron Reactive (FIRE) delivery of diagnostic or therapeutic agents
errEUROPEAN JOURNAL OF CANCER
IF7.1
err2024-10-01
err0
PREAI
errFontaine, S.; Lee, G.; Renslo, A.; Collisson, E.
err分享
err收藏
Synthesis and In Vivo Profiling of Desymmetrized Antimalarial Trioxolanes with Diverse Carbamate Side Chains具有不同氨基甲酸酯侧链的去对称化抗疟三恶唑烷的合成和体内分析
errACS MEDICINAL CHEMISTRY LETTERS
IF4
err2024-09-05
err1
errOAAI
errKlope, Matthew T.; Cardona, Juan A. Tapia; Chen, Jun; Gonciarz, Ryan L.; Cheng, Ke; Jaishankar, Priyadarshini; Kim, Julie; Legac, Jenny; Rosenthal, Philip J.; Renslo, Adam R.
err分享
err收藏
A tandem activity- based sensing and labeling strategy reveals antioxidant response element regulation of labile iron pools
errPROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
IF9.1
err2024-07-05
err3
errOAAI
errPezacki, Aidan T.; Gonciarz, Ryan L.; Okamura, Toshitaka; Matier, Carson D.; Torrente, Laura; Cheng, Ke; Miller, Sophia G.; Ralle, Martina; Ward, Nathan P.; DeNicola, Gina M.; Renslo, Adam R.; Chang, Christopher J.
err分享
err收藏
Development of covalent chemogenetic K 2P channel activators
errCELL CHEMICAL BIOLOGY
IF7.2
err2024-07-01
err1
errOAAI
errDeal, Parker E.; Lee, Haerim; Mondal, Abhisek; Lolicato, Marco; Mendonca, Philipe Ribeiro Furtado de; Black, Holly; Jang, Seil; El-Hilali, Xochina; Bryant, Clifford; Isacoff, Ehud Y.; Renslo, Adam R.; Minor, Daniel L.
err分享
err收藏
In vivo bioluminescence imaging of labile iron in xenograft models and liver using an iron-activatable form of D-luciferin
errCELL CHEMICAL BIOLOGY
IF7.2
err2023-11-01
err5
PREAI
errGonciarz, Ryan L.; Jiang, Honglin; Tram, Linh; Hugelshofer, Cedric L.; Ekpenyong, Oscar; Knemeyer, Ian; Aron, Allegra T.; Chang, Christopher J.; Flygare, John A.; Collisson, Eric A.; Renslo, Adam R.
err分享
err收藏
Imaging-Selected Host Responses in the Context of Infections在感染的情况下成像选择的宿主反应
errJOURNAL OF INFECTIOUS DISEASES
IF4.5
err2023-10-03
err2
errOAAI
errFoss, Catherine A.; Renslo, Adam R.
err分享
err收藏
Structure-Based Optimization of Covalent, Small-Molecule Stabilizers of the 14-3-3s/ERa Protein-Protein Interaction from Nonselective Fragments
errJOURNAL OF THE AMERICAN CHEMICAL SOCIETY
IF15.6
err2023-09-07
err15
errOAAI
errKonstantinidou, Markella; Visser, Emira J.; Vandenboorn, Edmee; Chen, Sheng; Jaishankar, Priyadarshini; Overmans, Maurits; Dutta, Shubhankar; Neitz, R. Jeffrey; Renslo, Adam R.; Ottmann, Christian; Brunsveld, Luc; Arkin, Michelle R.
err分享
err收藏
From Tethered to Freestanding Stabilizers of 14-3-3 Protein-Protein Interactions through Fragment Linking
errANGEWANDTE CHEMIE-INTERNATIONAL EDITION
IF16.9
err2023-08-01
err9
errOAAI
errVisser, Emira J.; Jaishankar, Priyadarshini; Sijbesma, Eline; Pennings, Marloes A. M.; Vandenboorn, Edmee M. F.; Guillory, Xavier; Neitz, R. Jeffrey; Morrow, John; Dutta, Shubhankar; Renslo, Adam R.; Brunsveld, Luc; Arkin, Michelle R.; Ottmann, Christian
err分享
err收藏
Systematic Study of Heteroarene Stacking Using a Congeneric Set of Molecular Glues for Procaspase-6
errJOURNAL OF MEDICINAL CHEMISTRY
IF6.8
err2023-07-05
err2
errOAAI
errTogo, Takaya; Tram, Linh; Denton, Laura G.; ElHilali-Pollard, Xochina; Gu, Jun; Jiang, Jinglei; Liu, Chenglei; Zhao, Yan; Zhao, Yanlong; Zheng, Yinzhe; Zheng, Yunping; Yang, Jingjing; Fan, Panpan; Arkin, Michelle R.; Harma, Harri; Sun, Deqian; Canan, Stacie S.; Wheeler, Steven E.; Renslo, Adam R.
err分享
err收藏
Artefenomel Regioisomer RLA-3107 Is a Promising Lead for the Discovery of Next-Generation Endoperoxide Antimalarials
errACS MEDICINAL CHEMISTRY LETTERS
IF4
err2023-04-04
err6
errOAAI
errBlank, Brian R.; Gut, Jiri; Rosenthal, Philip J.; Renslo, Adam R.
err分享
err收藏

研究方向

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M
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