James M. Mullin - Publications, H-index & Citations

James M. Mullin

Lankenau Institute for Medical Research

38H指数

168论文数

5.1K被引数

收录论文 57

发表时间

Orally Administered Zinc Gluconate Induces Tight Junctional Remodeling and Reduces Passive Transmucosal Permeability Across Human Intestine in a Patient-Based Study 口服葡萄糖酸锌诱导紧密连接重塑并减少人肠道被动跨黏膜通透性：一项基于患者的研究

International Journal of Molecular Sciences 2025, Vol. 26, Page 8540

IF4.9

2025-09-02

OAAI

Elizabeth A. Del Rio; Mary Carmen Valenzano; Katherine M. DiGuilio; Elizabeth Rybakovsky; Stephanie Kjelstrom; Georgia Montone; Giancarlo Mercogliano; Gary Newman; Patricia Wong; Nicole Albert; Victoria Burris; Kelly Szymanski; Amanda Rodriguez; Erin Hollis; Andrew Kossenkov; James M. Mullin

Quantitative Systems Toxicology Modeling of Acetaminophen Pharmacokinetics and Hepatic Biomarkers After Overdoses of Extended-Release and Immediate-Release Formulations in Adults With Chronic Alcohol Use or Low Glutathione 成人慢性酒精使用或低谷胱甘肽水平者服用缓释和即释剂型过量后，阿司匹林药代动力学与肝源性生物标志物的定量系统毒理学建模

CPT-PHARMACOMETRICS & SYSTEMS PHARMACOLOGY

IF3

2025-05-14

OAAI

Kyunghee Yang; James J. Beaudoin; Brett A. Howell; James Mullin; Elham Amini; John C. K. Lai; Cathy K. Gelotte; Sury Sista; Evren Atillasoy

Lipoic Acid Effects on Caco-2 Intestinal Epithelial Barrier Function

AMERICAN JOURNAL OF GASTROENTEROLOGY

IF7.6

2024-10-01

PREAI

DiGuilio, Katherine M.; Del Rio, Elizabeth A.; Spadea, Rocco; Valenzano, Mary C.; Mullin, James M.

Yeast Bax Inhibitor (Bxi1p/Ybh3p) is a Calcium Channel in E. coli

FASEB JOURNAL

IF4.2

2022-05-13

PREAI

Aguiar, Julia D.; Crago, Madelyn; Mullin, James; Kalhorn, John; Mello, Nicholas; Raffa, Amanda; Strakosha, Aleksander; Austriaco, Nicanor

Best Practices in the Development and Validation of Physiologically Based Biopharmaceutics Modeling. A Workshop Summary Report

JOURNAL OF PHARMACEUTICAL SCIENCES

IF3.8

2021-02-01

OAAI

Parrott, Neil; Suarez-Sharp, Sandra; Kesisoglou, Filippos; Pathak, Shriram M.; Good, David; Wagner, Christian; Dallmann, Andre; Mullin, James; Patel, Nikunjkumar; Riedmaier, Arian Emami; Mitra, Amitava; Raines, Kimberly; Butler, James; Kakhi, Maziar; Li, Min; Zhao, Yang; Tsakalozou, Eleftheria; Flanagan, Talia; Dressman, Jennifer; Pepin, Xavier

Improvements in the dysfunctional right ventricle with Macitentan treatment in a sugen/hypoxic rat model of pulmonary hypertension

EUROPEAN RESPIRATORY JOURNAL

IF21

2020-10-28

PREAI

Murphy, Gerard; Jayasekera, Geeshath; Mullin, James; Gallagher, Lindsay; Dempsie, Yvonne; Welsh, David J.

Epithelial barrier function properties of the 16HBE14o-human bronchial epithelial cell culture model

BIOSCIENCE REPORTS

IF4.7

2020-10-16

OAAI

Callaghan, Patrick J.; Ferrick, Bryan; Rybakovsky, Elizabeth; Thomas, Sunil; Mullin, James M.

Yeast Bax Inhibitor (Bxi1p/Ybh3p) is a calcium channel in E. coli

FASEB JOURNAL

IF4.2

2020-04-17

OAAI

Kalhorn, John; Raffa, Amanda; Strakosha, Aleksander; Mullin, James; Mello, Nicholas; Austriaco, Nicanor

Macitentan treatment improves the dysfunctional right ventricle in a sugen/hypoxic rat model of pulmonary hypertension

EUROPEAN RESPIRATORY JOURNAL

IF21

2019-11-21

PREAI

Murphy, Gerard; Jayasekera, Geeshath; Mullin, James; Gallagher, Lindsay; Dempsie, Yvonne; Welsh, David J.

REPEAT CARDIAC MRI TO DETERMINE CHANGES IN THE SUGEN/HYPOXIC RIGHT VENTRICLE WITH MACITENTAN THERAPY

HEART

IF4.4

2019-05-01

PREAI

Murphy, Gerard; Jayasekera, Geeshath; Mullin, James; Gallagher, Lindsay; Welsh, David

Intestinal barrier tightening by a cell-penetrating antibody to Bin1, a candidate target for immunotherapy of ulcerative colitis

JOURNAL OF CELLULAR BIOCHEMISTRY

IF2.8

2018-09-30

OAAI

Thomas, Sunil; Hoxha, Kevther; Alexander, Walker; Gilligan, John; Dilbarova, Rima; Whittaker, Kelly; Kossenkov, Andrew; Prendergast, George C.; Mullin, James M.

Yeast Bax Inhibitor, BXI1, is involved in calcium homeostasis of the ER in Saccharomyces cerevisiae

CANCER RESEARCH

IF16.6

2018-07-01

PREAI

Andrews, Nicholas; Mello, Nicholas; McDonough, Liam; Alisch, Joseph; Eagan, David; Mullin, James; Gonzalez, Alfredo; Austriaco, Nicanor

Improvement of Human-Oral-Epithelial-Barrier Function and of Tight Junctions by Micronutrients

JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

IF6.2

2017-12-07

PREAI

Rybakovsky, Elizabeth; Valenzano, Mary Carmen; Deis, Rachael; DiGuilio, Katherine M.; Thomas, Sunil; Mullin, James M.

Longitudinal cardiac changes in a SUGEN/Hypoxic Rat Model of Pulmonary Hypertension determined by Cardiac MRI

EUROPEAN RESPIRATORY JOURNAL

IF21

2017-12-06

PREAI

Jayasekera, Geeshath; Wilson, Kathryn; Buist, Hanna; Hughes, C.; Nilsen, M.; Church, Colin; Gallagher, L.; Mullin, J.; Maclean, M.; Holmes, W.; Welsh, David; Peacock, Andrew

Yeast Bax Inhibitor (BXI1) is involved in redox and calcium homeostasis of the ER in S-cerevisiae

CANCER RESEARCH

IF16.6

2017-07-01

PREAI

Eagan, David; Alisch, Joseph; McDonough, Liam; Benko, Savannah; Jacob, Walter; Ritzer, Lukas; Mullin, James; O'Reilly, John; Austriaco, Nicanor

The Effect of Orally-Administered Zinc on Barrett's Epithelia Micro Rnas

GASTROINTESTINAL ENDOSCOPY

IF7.5

2017-05-01

PREAI

Valenzano, Mary Carmen; Fong, Louise; Mayilvaganan, Barani; Connor, Laura; Huntington, William; Urbas, Ryan; Mercogliano, Giancarlo; Newman, Gary; Mullin, James M.

The Host Microbiome Regulates and Maintains Human Health: A Primer and Perspective for Non-Microbiologists

CANCER RESEARCH

IF16.6

2017-04-13

272

OAAI

Thomas, Sunil; Izard, Jacques; Walsh, Emily; Batich, Kristen; Chongsathidkiet, Pakawat; Clarke, Gerard; Sela, David A.; Muller, Alexander J.; Mullin, James M.; Albert, Korin; Gilligan, John P.; DiGuilio, Katherine; Dilbarova, Rima; Alexander, Walker; Prendergast, George C.

COBALT CHLORIDE COMPROMISES TRANSEPITHELIAL BARRIER PROPERTIES OF CACO-2 HUMAN GASTROINTESTINAL EPITHELIAL CELL LAYERS

GASTROENTEROLOGY

IF25.1

2017-04-01

PREAI

DiGuilio, Katherine; Valenzano, Mary Carmen; Rybakovsky, Elizabeth; Mullin, James M.

IMI - Oral biopharmaceutics tools project - Evaluation of bottom-up PBPK prediction success part 3: Identifying gaps in system parameters by analysing In Silico performance across different compound classes

EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES

IF4.7

2017-01-01

OAAI

Darwich, Adam S.; Margolskee, Alison; Pepin, Xavier; Aarons, Leon; Galetin, Aleksandra; Rostami-Hodjegan, Amin; Carlert, Sara; Hammarberg, Maria; Hilgendorf, Constanze; Johansson, Pernilla; Karlsson, Eva; Murphy, Donal; Tannergren, Christer; Thorn, Helena; Yasin, Mohammed; Mazuir, Florent; Nicolas, Olivier; Ramusovic, Sergej; Xu, Christine; Pathak, Shriram M.; Korjamo, Timo; Laru, Johanna; Malkki, Jussi; Pappinen, Sari; Tuunainen, Johanna; Dressman, Jennifer; Hansmann, Simone; Kostewicz, Edmund; He, Handan; Heimbach, Tycho; Wu, Fan; Hoft, Carolin; Pang, Yan; Bolger, Michael B.; Huehn, Eva; Lukacova, Viera; Mullin, James M.; Szeto, Ke X.; Costales, Chester; Lin, Jian; McAllister, Mark; Modi, Sweta; Rotter, Charles; Varma, Manthena; Wong, Mei; Mitra, Amitava; Bevernage, Jan; Biewenga, Jeike; Van Peer, Achiel; Lloyd, Richard; Shardlow, Carole; Langguth, Peter; Mishenzon, Irina; Mai Anh Nguyen; Brown, Jonathan; Lennernas, Hans; Abrahamsson, Bertil

IMI - Oral biopharmaceutics tools project - Evaluation of bottom-up PBPK prediction success part 2: An introduction to the simulation exercise and overview of results

EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES

IF4.7

2017-01-01

OAAI

Margolskee, Alison; Darwich, Adam S.; Pepin, Xavier; Aarons, Leon; Galetin, Aleksandra; Rostami-Hodjegan, Amin; Carlert, Sara; Hammarberg, Maria; Hilgendorf, Constanze; Johansson, Pernilla; Karlsson, Eva; Murphy, Donal; Tannergren, Christer; Thorn, Helena; Yasin, Mohammed; Mazuir, Florent; Nicolas, Olivier; Ramusovic, Sergej; Xu, Christine; Pathak, Shriram M.; Korjamo, Timo; Laru, Johanna; Malkki, Jussi; Pappinen, Sari; Tuunainen, Johanna; Dressman, Jennifer; Hansmanni, Simone; Kostewicz, Edmund; He, Handan; Heimbach, Tycho; Wu, Fan; Hoft, Carolin; Laplanche, Loic; Pang, Yan; Bolger, Michael B.; Huehn, Eva; Lukacova, Viera; Mullin, James M.; Szeto, Ke X.; Costales, Chester; Lin, Jian; McAllister, Mark; Modi, Sweta; Rotter, Charles; Varma, Manthena; Wong, Mei; Mitra, Amitava; Bevernage, Jan; Biewenga, Jeike; Van Peer, Achiel; Lloyd, Richard; Shardlow, Carole; Langguth, Peter; Mishenzon, Irina; Mai Anh Nguyen; Brown, Jonathan; Lennernas, Hans; Abrahamsson, Bertil

研究方向