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M

Michael J. Keiser

University of California, San Francisco

32H指数
124论文数
8.4K被引数
收录论文 43
发表时间
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Learning precise segmentation of neurofibrillary tangles from rapid manual point annotations从快速手动点注释中学习精确的神经纤维缠结分割
errScientific Reports
IF3.9
err2026-08-28
err0
errOAAI
errSina Ghandian; Liane Albarghouthi; Kiana Nava; Shivam R. Rai Sharma; Lise Minaud; Laurel Beckett; Naomi Saito; Charles DeCarli; Robert A. Rissman; Andrew F. Teich; Lee-Way Jin; Brittany N. Dugger; Michael J. Keiser
err分享
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Network-aware self-supervised learning enables high-content phenotypic screening for genetic modifiers of neuronal activity dynamics网络感知的自我监督学习可以对神经元活动动力学的遗传修饰进行高含量的表型筛选
errNature Machine Intelligence
IF23.9
err2025-12-17
err0
PREAI
errParker Grosjean; Kaivalya Shevade; Cuong Nguyen; Sarah Ancheta; Karl Mader; Ivan Franco; Seok-Jin Heo; Greyson Lewis; Dehua Zhao; Bhairavi Tolani; Steven Boggess; Angelique Di Domenico; Erik Ullian; Shawn Shafer; Adam Litterman; Laralynne Przybyla; Michael J. Keiser; Jamie Ifkovits; Adam Yala; Martin Kampmann
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Deep learning finds convergent melanocytic morphology despite noisy archival slides深度学习能够在嘈杂的档案幻灯片中找到收敛的黑色素细胞形态。
errCell Reports Methods
IF4.5
err2025-10-20
err0
errOAAI
errMikio Tada; Garrett Gaskins; Sina Ghandian; Nicholas Mew; Michael James Keiser; Elizabeth Sarah Keiser
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Autoparty: Machine Learning-Guided Visual Inspection of Molecular Docking ResultsAutoparty：机器学习引导的分子对接结果可视化检测
errJournal of Chemical Information and Modeling
IF5.3
err2025-07-29
err0
PREAI
errLaura Shub; Magdalena Korczynska; Duncan F. Muir; Fang-Yu Lin; Brendan W. Hall; Alan M. Mathiowetz; Michael J. Keiser
err分享
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Cell-type-directed network-correcting combination therapy for Alzheimer’s disease细胞类型定向的网络校正联合疗法治疗阿尔茨海默病
errCell
IF42.5
err2025-07-21
err0
errOAAI
errYaqiao Li; Carlota Pereda Serras; Jessica Blumenfeld; Min Xie; Yanxia Hao; Elise Deng; You Young Chun; Julia Holtzman; Alice An; Seo Yeon Yoon; Xinyu Tang; Antara Rao; Sarah Woldemariam; Alice Tang; Alex Zhang; Jeffrey Simms; Iris Lo; Tomiko Oskotsky; Michael J. Keiser; Yadong Huang; Marina Sirota
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Accelerating biomedical discoveries in brain health through transformative neuropathology of aging and neurodegeneration通过衰老和神经退行性变的变革性神经病理学加速脑健康生物医学发现
errNeuron
IF15
err2025-07-18
err0
errOAAI
errMelissa E. Murray; Colin Smith; Vilas Menon; C. Dirk Keene; Ed Lein; Michael Hawrylycz; Adriano Aguzzi; Brett Benedetti; Katja Brose; Kelsey Caetano-Anolles; Maria Inmaculada Cobos Sillero; John F. Crary; Philip L. De Jager; Arline Faustin; Margaret E. Flanagan; Ozgun Gokce; Seth G.N. Grant; Lea T. Grinberg; David A. Gutman; Elizabeth M.C. Hillman; Zhi Huang; David J. Irwin; David T. Jones; Alifiya Kapasi; Celeste M. Karch; Walter T. Kukull; Tammaryn Lashley; Edward B. Lee; Thomas Lehner; Laura Parkkinen; Maria Pedersen; Dominique Pritchett; Matthew H. Rutledge; Julie A. Schneider; William W. Seeley; Claire E. Shepherd; Tara L. Spires-Jones; Judith A. Steen; Margaret Sutherland; Sanja Vickovic; Bin Zhang; David J. Stewart; Michael J. Keiser; Jacob W. Vogel; Brittany N. Dugger; Hemali Phatnani
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The polypharmacology of psychedelics reveals multiple targets for potential therapeutics致幻剂的药物多效性揭示了潜在治疗药物的多重靶点
errNeuron
IF15
err2025-07-18
err0
PREAI
errManish K. Jain; Ryan H. Gumpper; Samuel T. Slocum; Gavin P. Schmitz; Jakob S. Madsen; Tia A. Tummino; Carl-Mikael Suomivuori; Xi-Ping Huang; Laura Shub; Jeffrey F. DiBerto; Kuglae Kim; Chelsea DeLeon; Brain E. Krumm; Jonathan F. Fay; Michael Keiser; Alexander S. Hauser; Ron O. Dror; Brian Shoichet; David E. Gloriam; David E. Nichols; Bryan L. Roth
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ChromaFactor: Deconvolution of single-molecule chromatin organization with non-negative matrix factorizationChromaFactor：使用非负矩阵分解对单分子染色质组织进行反卷积
errplos biology
IF3.6
err2025-02-18
err0
errOAAI
errGunsalus, Laura M.; Keiser, Michael J.
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Fuzz Testing Molecular Representation Using Deep Variational Anomaly Generation使用深变分异常生成的模糊测试分子表示
errJOURNAL OF CHEMICAL INFORMATION AND MODELING
IF5.3
err2025-02-05
err0
errOAAI
errNogueira, Victor H. R.; Sharma, Rishabh; Guido, Rafael V. C.; Keiser, Michael J.
err分享
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Deep phenotypic profiling of neuroactive drugs in larval zebrafish
errNATURE COMMUNICATIONS
IF15.7
err2024-11-17
err0
errOAAI
errGendelev, Leo; Taylor, Jack; Myers-Turnbull, Douglas; Chen, Steven; McCarroll, Matthew N.; Arkin, Michelle R.; Kokel, David; Keiser, Michael J.
err分享
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Retrieval Augmented Docking Using Hierarchical Navigable Small Worlds
errJOURNAL OF CHEMICAL INFORMATION AND MODELING
IF5.3
err2024-10-03
err0
errOAAI
errHall, Brendan W.; Keiser, Michael J.
err分享
err收藏
Learning chemical sensitivity reveals mechanisms of cellular response
errCOMMUNICATIONS BIOLOGY
IF5.1
err2024-09-15
err1
errOAAI
errConnell, William; Garcia, Kristle; Goodarzi, Hani; Keiser, Michael J.
err分享
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Proximity Graph Networks: Predicting Ligand Affinity with Message Passing Neural Networks邻近图网络: 用消息传递神经网络预测配体亲和力
errJOURNAL OF CHEMICAL INFORMATION AND MODELING
IF5.3
err2024-07-02
err1
errOAAI
errGale-Day, Zachary J.; Shub, Laura; Chuang, Kangway V.; Keiser, Michael J.
err分享
err收藏
Toward a generalizable machine learning workflow for neurodegenerative disease staging with focus on neurofibrillary tangles
errACTA NEUROPATHOLOGICA COMMUNICATIONS
IF5.7
err2023-12-18
err6
errOAAI
errVizcarra, Juan C.; Pearce, Thomas M.; Dugger, Brittany N.; Keiser, Michael J.; Gearing, Marla; Crary, John F.; Kiely, Evan J.; Morris, Meaghan; White, Bartholomew; Glass, Jonathan D.; Farrell, Kurt; Gutman, David A.
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In silico discovery of repetitive elements as key sequence determinants of 3D genome folding
errCELL GENOMICS
IF9
err2023-10-01
err6
errOAAI
errGunsalus, Laura M.; Keiser, Michael J.; Pollard, Katherine S.
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Learning fast and fine-grained detection of amyloid neuropathologies from coarse-grained expert labels从粗粒度的专家标签中学习淀粉样蛋白神经病理学的快速和细粒度检测
errCOMMUNICATIONS BIOLOGY
IF5.1
err2023-06-24
err2
errOAAI
errWong, Daniel R.; Magaki, Shino D.; Vinters, Harry V.; Yong, William H.; Monuki, Edwin S.; Williams, Christopher K.; Martini, Alessandra C.; DeCarli, Charles; Khacherian, Chris; Graff, John P.; Dugger, Brittany N.; Keiser, Michael J.
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Prioritizing Virtual Screening with Interpretable Interaction Fingerprints
errJOURNAL OF CHEMICAL INFORMATION AND MODELING
IF5.3
err2022-09-14
err16
errOAAI
errFassio, Alexandre, V; Shub, Laura; Ponzoni, Luca; McKinley, Jessica; O'Meara, Matthew J.; Ferreira, Rafaela S.; Keiser, Michael J.; de Melo Minardi, Raquel C.
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Trans-channel fluorescence learning improves high-content screening for Alzheimer's disease therapeutics
errNATURE MACHINE INTELLIGENCE
IF23.9
err2022-05-30
err7
errOAAI
errWong, Daniel R.; Conrad, Jay; Johnson, Noah R.; Ayers, Jacob; Laeremans, Annelies; Lee, Joanne C.; Lee, Jisoo; Prusiner, Stanley B.; Bandyopadhyay, Sourav; Butte, Atul J.; Paras, Nick A.; Keiser, Michael J.
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Deep learning from multiple experts improves identification of amyloid neuropathologies来自多位专家的深度学习改善了淀粉样蛋白神经病理的识别
errACTA NEUROPATHOLOGICA COMMUNICATIONS
IF5.7
err2022-04-28
err12
errOAAI
errWong, Daniel R.; Tang, Ziqi; Mew, Nicholas C.; Das, Sakshi; Athey, Justin; McAleese, Kirsty E.; Kofler, Julia K.; Flanagan, Margaret E.; Borys, Ewa; White, Charles L.; Butte, Atul J.; Dugger, Brittany N.; Keiser, Michael J.
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Stress testing reveals gaps in clinic readiness of image-based diagnostic artificial intelligence models
errNPJ DIGITAL MEDICINE
IF15.1
err2021-01-21
err25
errOAAI
errYoung, Albert T.; Fernandez, Kristen; Pfau, Jacob; Reddy, Rasika; Cao, Nhat Anh; von Franque, Max Y.; Johal, Arjun; Wu, Benjamin V.; Wu, Rachel R.; Chen, Jennifer Y.; Fadadu, Raj P.; Vasquez, Juan A.; Tam, Andrew; Keiser, Michael J.; Wei, Maria L.
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研究方向

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合作学者
合作期刊
S
Stanley B. Prusiner
H 指数: 155 · 论文数: 653
R
Richard P. Lifton
H 指数: 150 · 论文数: 571
J
Jennifer A. Doudna
H 指数: 149 · 论文数: 675
P
Philip L. De Jager
H 指数: 147 · 论文数: 1.1K
D
David Jones
H 指数: 144 · 论文数: 1.5K
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