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C

Carmine Ostacolo

University of Salerno
H指数:29
被引数:2,142

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Molecular Basis for Activation to Inhibition Switching in Kv7.2 Channel Modulators

Kv7.2通道调节剂中从激活到抑制的转换的分子机制

Angewandte Chemie-International Edition
IF16.9
2026-08-280
OAAI
Tania Ciaglia; Giusy Carleo; Zhenni Yang; Francesca Di Matteo; Federica De Rosa; Gerardina Smaldone; Zhao-Bing Gao; Marco D'Alì; Rita Turcio; Demin Ma; Veronica Di Sarno; Nannan Su; Salvatore Vincenzo Giofrè; Giacomo Pepe; Pietro Campiglia; Alessia Bertamino; Francesco Miceli; Jiangtao Guo; Nunzio Iraci; Carmine Ostacolo; Maurizio Taglialatela
Metabolic Reprogramming Associated with Ferroptosis Protection by an Indole-Based Antioxidant in Aβ(25–35)-Treated SH-SY5Y Cells

吲哚基抗氧化剂介导的 ferroptosis 保护作用与 Aβ(25–35) 处理的 SH-SY5Y 细胞中代谢重编程的关系

Antioxidants
IF6.6
2026-07-280
OA
Mariapia Vietri; Enza Napolitano; Maria Rosaria Miranda; Carmen Marino; Simona Musella; Veronica Di Sarno; Carmine Ostacolo; Michele Manfra; Pietro Campiglia; Mario Felice Tecce; Anna Maria D’Ursi; Ornella Moltedo; Alessia Bertamino; Tania Ciaglia; Vincenzo Vestuto
Targeting Cathepsins in Neurodegeneration: Biochemical Advances

靶向神经退行性疾病中的组织蛋白酶：生物化学进展

Biomedicines
IF3.9
2026-03-040
OAAI
Francesca Di Matteo; Mariapia Vietri; Simone D’Alessio; Tania Ciaglia; Erica Federica Vestuto; Giacomo Pepe; Ornella Moltedo; Veronica Di Sarno; Simona Musella; Carmine Ostacolo; Fabio Cominelli; Pietro Campiglia; Alessia Bertamino; Maria Rosaria Miranda; Vincenzo Vestuto
An adamantylureido-benzylamide aniline as FLAP/sEH dual inhibitor: rational design, in vitro and in vivo lipidomic profiling

adamantylureido-苄酰胺苯胺作为FLAP/sEH双抑制剂：理性设计、体外及体内脂质组学分析

European Journal of Medicinal Chemistry
IF5.9
2025-11-030
PRE
Tania Ciaglia; Danilo D’Avino; Paul M. Jordan; Simone Di Micco; Simona Musella; Hannes Engelbrecht; Lukas Klaus Peltner; Veronica Di Sarno; Fabrizio Merciai; Sara Perna; Gerardina Smaldone; Francesca Di Matteo; Valeria Napolitano; Rosario Stimoli; Giuseppe Bifulco; Giacomo Pepe; Eduardo Maria Sommella; Manuela Giovanna Basilicata; Giovanna Aquino; Isabel M. Gomez-Monterrey; Pietro Campiglia; Carmine Ostacolo; Oliver Werz; Antonietta Rossi; Alessia Bertamino; Michele Manfra
Untargeted Diversity-Oriented Synthesis for the Discovery of New Antitumor Agents: An Integrated Approach of Inverse Virtual Screening; Bioinformatics; and Omics for Target Deconvolution

靶向多样性导向合成用于抗癌新药发现：一种整合反向虚拟筛选、生物信息学和组学技术进行靶点解卷积的综合方法

Journal of Medicinal Chemistry
IF6.8
2025-07-240
OA
Tania Ciaglia; Valeria Napolitano; Maria Rosaria Miranda; Danila La Gioia; Simona Musella; Aniello Schiano Moriello; Fabrizio Merciai; Veronica Di Sarno; Simona De Vita; Ester Colarusso; Gerardina Smaldone; Francesca Di Matteo; Eduardo Maria Sommella; Poulami Kumar; Marco Allarà; Alessia Ligresti; Isabel M. Gomez-Monterrey; Giuseppe Bifulco; Gianluigi Lauro; Pietro Campiglia; Carmine Ostacolo; Vincenzo Vestuto; Alessia Bertamino
The fast-dissociating D2 antagonist antipsychotic JNJ-37822681 is a neuronal Kv7 channel opener: Potential repurposing for epilepsy treatment

快速解离的D2拮抗剂型抗精神病药JNJ-37822681是一种神经元Kv7通道开放剂：用于癫痫治疗的潜在再利用

British Journal of Pharmacology
IF7.7
2025-07-230
OAAI
Lidia Carotenuto; Oliver Keminer; Giusy Carleo; Andrea Zaliani; Antonio Leo; Rita Citraro; Giovambattista De Sarro; Nina Dirkx; Marcus Kaji; Sarah Weckhuysen; Jeanette Reinshagen; Vincenzo Barrese; Natascia Guida; Carmine Ostacolo; Francesco Miceli; Philip Gribbon; Maurizio Taglialatela
Novel Para-Phenylenediamine-Based Derivatives as Receptor Tyrosine Kinase-like Orphan Receptor 1 (ROR1) Inhibitors: An In Vitro Preliminary Characterization

新型对苯二胺基衍生物作为受体酪氨酸激酶样孤寡受体1（ROR1）抑制剂：体外初步表征

ChemMedChem
IF3.4
2025-06-010
PREAI
Gerardina Smaldone; Maria Rosaria Miranda; Francesca Di Matteo; Valeria Napolitano; Michela Aliberti; Simona Musella; Veronica Di Sarno; Gianluigi Lauro; Giuseppe Bifulco; Giacomo Pepe; Giovanna Aquino; Mario Felice Tecce; Isabel Maria Gomez-Monterrey; Pietro Campiglia; Carmine Ostacolo; Alessia Bertamino; Vincenzo Vestuto; Tania Ciaglia
Furazanopyrazine-based novel promising anticancer agents interfering with the eicosanoid biosynthesis pathways by dual mPGES-1 and sEH inhibition
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
IF5.9
2025-05-010
OAAI
Lauro, Gianluigi; Aliberti, Michela; De Nisco, Mauro; Pedatella, Silvana; Pepe, Giacomo; Basilicata, Manuela Giovanna; Chini, Maria Giovanna; Fischer, Katrin; Hofstetter, Robert K.; Werz, Oliver; Ferraro, Maria Grazia; Piccolo, Marialuisa; Irace, Carlo; Saviano, Anella; Campiglia, Pietro; Bertamino, Alessia; Ostacolo, Carmine; Ciaglia, Tania; Manfra, Michele; Bifulco, Giuseppe
Neuroprotective Potential of Indole-Based Compounds: A Biochemical Study on Antioxidant Properties and Amyloid Disaggregation in Neuroblastoma Cells
ANTIOXIDANTS
IF6.6
2024-12-230
OAAI
Ciaglia, Tania; Miranda, Maria Rosaria; Di Micco, Simone; Vietri, Mariapia; Smaldone, Gerardina; Musella, Simona; Di Sarno, Veronica; Auriemma, Giulia; Sardo, Carla; Moltedo, Ornella; Pepe, Giacomo; Bifulco, Giuseppe; Ostacolo, Carmine; Campiglia, Pietro; Manfra, Michele; Vestuto, Vincenzo; Bertamino, Alessia
A Comprehensive In Vitro Characterization of a New Class of Indole-Based Compounds Developed as Selective Haspin Inhibitors
JOURNAL OF MEDICINAL CHEMISTRY
IF6.8
2024-07-221
PRE
Vestuto, Vincenzo; Ciaglia, Tania; Musella, Simona; Di Sarno, Veronica; Smaldone, Gerardina; Di Matteo, Francesca; Scala, Maria Carmina; Napolitano, Valeria; Miranda, Maria Rosaria; Amodio, Giuseppina; Novi, Sara; Pepe, Giacomo; Basilicata, Manuela Giovanna; Gazzillo, Erica; Pace, Simona; Gomez-Monterrey, Isabel M.; Sala, Marina; Bifulco, Giuseppe; Tecce, Mario Felice; Campiglia, Pietro; Ostacolo, Carmine; Lauro, Gianluigi; Manfra, Michele; Bertamino, Alessia
KCNT1 Channel Blockers: A Medicinal Chemistry Perspective

KCNT1通道阻滞剂: 药物化学观点

MOLECULES
IF4.6
2024-06-202
OAAI
Di Matteo, Francesca; Mancuso, Francesca; Turcio, Rita; Ciaglia, Tania; Stagno, Claudio; Di Chio, Carla; Campiglia, Pietro; Bertamino, Alessia; Giofre, Salvatore Vincenzo; Ostacolo, Carmine; Iraci, Nunzio
In Silico Assisted Identification, Synthesis, and In Vitro Pharmacological Characterization of Potent and Selective Blockers of the Epilepsy-Associated KCNT1 Channel
JOURNAL OF MEDICINAL CHEMISTRY
IF6.8
2024-05-235
OAAI
Iraci, Nunzio; Carotenuto, Lidia; Ciaglia, Tania; Belperio, Giorgio; Di Matteo, Francesca; Mosca, Ilaria; Carleo, Giusy; Basilicata, Manuela Giovanna; Ambrosino, Paolo; Turcio, Rita; Puzo, Deborah; Pepe, Giacomo; Gomez-Monterrey, Isabel; Soldovieri, Maria Virginia; Di Sarno, Veronica; Campiglia, Pietro; Miceli, Francesco; Bertamino, Alessia; Ostacolo, Carmine; Taglialatela, Maurizio
Novel pyrrole based CB2 agonists: New insights on CB2 receptor role in regulating neurotransmitters' tone
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
IF5.9
2024-04-014
OAAI
Di Micco, Simone; Ciaglia, Tania; Salviati, Emanuela; Michela, Perrone; Kostrzewa, Magdalena; Musella, Simona; Moriello, Aniello Schiano; Di Sarno, Veronica; Smaldone, Gerardina; Di Matteo, Francesca; Capolupo, Ilaria; Infantino, Rosmara; Bifulco, Giuseppe; Pepe, Giacomo; Sommella, Eduardo M.; Kumar, Poulami; Basilicata, Manuela Giovanna; Allara, Marco; Sanchez-Fernandez, Nuria; Aso, Ester; Gomez-Monterrey, Isabel M.; Campiglia, Pietro; Ostacolo, Carmine; Maione, Sabatino; Ligresti, Alessia; Bertamino, Alessia
Peptidomimetics as potent dual SARS-CoV-2 cathepsin-L and main protease inhibitors: In silico design, synthesis and pharmacological characterization
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
IF5.9
2024-02-016
OAAI
Ciaglia, Tania; Vestuto, Vincenzo; Di Sarno, Veronica; Musella, Simona; Smaldone, Gerardina; Di Matteo, Francesca; Napolitano, Valeria; Miranda, Maria Rosaria; Pepe, Giacomo; Basilicata, Manuela Giovanna; Novi, Sara; Capolupo, Ilaria; Bifulco, Giuseppe; Campiglia, Pietro; Gomez-Monterrey, Isabel; Snoeck, Robert; Andrei, Graciela; Manfra, Michele; Ostacolo, Carmine; Lauro, Gianluigi; Bertamino, Alessia
A Combination of Polymethoxyflavones from Citrus sinensis and Prenylflavonoids from Humulus lupulus Counteracts IL-1β-Induced Differentiated Caco-2 Cells Dysfunction via a Modulation of NF-?B/Nrf2 Activation
ANTIOXIDANTS
IF6.6
2023-08-166
OAAI
Restivo, Ignazio; Basilicata, Manuela Giovanna; Giardina, Ilenia Concetta; Massaro, Alessandro; Pepe, Giacomo; Salviati, Emanuela; Pecoraro, Camilla; Carbone, Daniela; Cascioferro, Stella; Parrino, Barbara; Diana, Patrizia; Ostacolo, Carmine; Campiglia, Pietro; Attanzio, Alessandro; D'Anneo, Antonella; Pojero, Fanny; Allegra, Mario; Tesoriere, Luisa
Design, Synthesis, and Pharmacological Characterization of a Potent Soluble Epoxide Hydrolase Inhibitor for the Treatment of Acute Pancreatitis
JOURNAL OF MEDICINAL CHEMISTRY
IF6.8
2023-06-198
OAAI
Musella, Simona; D'Avino, Danilo; Peltner, Lukas Klaus; Di Sarno, Veronica; Cerqua, Ida; Merciai, Fabrizio; Vestuto, Vincenzo; Ciaglia, Tania; Smaldone, Gerardina; Di Matteo, Francesca; Di Micco, Simone; Napolitano, Valeria; Bifulco, Giuseppe; Pepe, Giacomo; Sommella, Eduardo Maria; Basilicata, Manuela Giovanna; Aquino, Giovanna; Gomez-Monterrey, Isabel M. M.; Campiglia, Pietro; Ostacolo, Carmine; Roviezzo, Fiorentina; Werz, Oliver; Rossi, Antonietta; Bertamino, Alessia
Discovery and Optimization of Indoline-Based Compounds as Dual 5-LOX/sEH Inhibitors: In Vitro and In Vivo Anti-Inflammatory Characterization
JOURNAL OF MEDICINAL CHEMISTRY
IF6.8
2022-11-0117
OAAI
Cerqua, Ida; Musella, Simona; Peltner, Lukas Klaus; D'Avino, Danilo; Di Sarno, Veronica; Granato, Elisabetta; Vestuto, Vincenzo; Di Matteo, Rita; Pace, Simona; Ciaglia, Tania; Bilancia, Rossella; Smaldone, Gerardina; Di Matteo, Francesca; Di Micco, Simone; Bifulco, Giuseppe; Pepe, Giacomo; Basilicata, Manuela Giovanna; Rodriquez, Manuela; Gomez-Monterrey, Isabel M.; Campiglia, Pietro; Ostacolo, Carmine; Roviezzo, Fiorentina; Werz, Oliver; Rossi, Antonietta; Bertamino, Alessia

研究方向

暂未获取到该数据
P
Pietro Campiglia
H 指数:50论文数:435被引数:1.0万
A
Alessia Bertamino
H 指数:26论文数:117被引数:2,088
T
Tania Ciaglia
H 指数:15论文数:53被引数:732
V
Veronica Di Sarno
H 指数:19论文数:53被引数:1,101
S
Simona Musella
H 指数:23论文数:61被引数:1,324
G
Giacomo Pepe
H 指数:32论文数:121被引数:2,434
I
Isabel Gómez‐Monterrey
H 指数:30论文数:125被引数:3,872
V
Vincenzo Vestuto
H 指数:17论文数:50被引数:748
E
Eduardo Sommella
H 指数:32论文数:178被引数:3,283
M
Michele Manfra
H 指数:26论文数:87被引数:1,671