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周

周璐 (Lu Zhou)

fudan university

38H指数
153论文数
6.6K被引数
收录论文 95
发表时间
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Metabolic reprogramming drives pancreatic β cell neogenesis from α cells代谢重编程驱动胰腺α细胞向β细胞新生
errNature Chemical Biology
IF13.7
err2026-08-07
err0
PREAI
errYufeng Zhang; Guangxing Lu; Wenhao Xie; Peng Xu; Cenxi Liu; Olga Babosova; Jamie Christopher Reilly; Zhehui Li; Leshi Chen; Liying Zhou; Jing Gao; Lennart Enders; Xuelian Xiong; Mingyu Li; Stefan Kubicek; Bing Zhao; Zhe Feng; Biao Yu; Lu Zhou; He Huang; Jin Li
err分享
err收藏
Gut microbiota-derived lysine phenylacetylation impairs mitochondrial function and is alleviated by SIRT3肠道菌群衍生的赖氨酸苯乙酰化损害线粒体功能，并可通过SIRT3缓解
errCell Metabolism
IF30.9
err2026-06-24
err0
PREAI
errWei Du; Jun-Yu Xu; Yufeng Li; Mingya Zhang; Yidan Huang; Shaoqian Zhao; Ying Zhou; Lei Zhao; Kexin Xu; Linhui Zhai; Wensi Zhao; Jia Liu; Jiahui Ni; Junxiao Dai; Tianxian Liu; Jie Hong; Haowen Jiang; Shuliang Zhao; Jian Zhang; Lu Zhou
err分享
err收藏
Design; Synthesis; and Evaluation of Phenylpyrrole Derivatives as Small-Molecule Activators of BAX设计、合成与评价：作为BAX小分子激活剂的苯并吡咯衍生物
errJournal of Medicinal Chemistry
IF6.8
err2026-03-20
err0
PREAI
errWei Cai; Zuo Li; Meiling Zhao; Yiwen Gu; Chenyang Qiu; Mi Zhou; Wei Deng; Lu Zhou; Yan Li; Renxiao Wang
err分享
err收藏
Biocatalytic- and Chemoproteomic-Guided Discovery of a PHGDH Inhibitor from Chemoenzymatic-Promoted DNA-Encoded Libraries Selection Platform生物催化与化学蛋白质组学指导下的PHGDH抑制剂发现：基于化学酶促促进的DNA编码库筛选平台
errJournal of the American Chemical Society
IF15.6
err2025-11-20
err0
errOAAI
errYiwei Zhang; Yuqiu Lan; Rufeng Fan; Lei Feng; Guoliang Wang; Xinyuan Wu; Lulu Wen; Zhiqiang Duan; Yueyue Xia; Xudong Wang; Lingrui Zhang; Lu Zhou; Minjia Tan; Cangsong Liao; Xiaojie Lu
err分享
err收藏
A generalized strategy to kill leukemic cells by targeting the regulatory systems governing mitochondrial membrane potential一种通过靶向调控线粒体膜电位调控系统来杀灭白血病细胞的通用策略
errCell Reports
IF6.9
err2025-10-29
err0
errOAAI
errTing Liu; Ji-Hao Zhou; Yongbo Gong; Ying Zhang; Yongcan Ma; Xiaowen Zhang; Mohammad Minhajuddin; Wenjie Song; Zixuan Zhuang; Ana Vujovic; Youli Lu; Ang Jia; Rongqun Guo; Ruobing Ren; Lu Zhou; Yu Xiong; Linzhang Huang; Xingrong Du; Tong-Jin Zhao; Peng Li; Craig T. Jordan; Haobin Ye
err分享
err收藏
CBX4 acetoacetylation as an inhibitory mechanism of HIF-1α activityCBX4 乙酰乙酸化作为一种抑制 HIF-1α 活性的机制
errCell Chemical Biology
IF7.2
err2025-10-03
err0
PREAI
errHuiti Li; Ying Xu; Yimin Zheng; Zian Xue; Qingqing Li; Xinglong Jia; Lietao Weng; Lulu Jiang; Xiaoxue Ruan; Rong Zhang; Yue Yin; Liying Zhou; Fuyuan Li; He Huang; Jin Li; Minjia Tan; Jia Fan; Jiabin Cai; Guoqiang Chen; Lu Zhou
err分享
err收藏
Expanding the Chemistry of Acyl Diazo Electrophile as a Tunable Warhead for Covalent Targeting of KRAS (G12D) Mutant扩展酰基重氮亲电试剂的化学性质，作为一种可调谐的 Warhead 用于共价靶向 KRAS (G12D) 突变体
errJournal of Medicinal Chemistry
IF6.8
err2025-09-29
err0
PREAI
errTianbai Shuai; Rong Zhang; Zihang Yuan; Mingya Zhang; Zhongjiao Fan; Xiaoxue Ruan; Zhiyuan Qi; Wenhao Xie; Ping Liu; Motonari Uesugi; Qing Li; Zhibei Qu; Minjia Tan; Hua Su; Lu Zhou
err分享
err收藏
Under-five mortality burden in low- and middle-income countries set to increase under future warming低收入和中等收入国家在未来的升温情景下，五岁以下死亡率负担预计将增加。
errOne Earth
IF15.3
err2025-08-25
err0
PREAI
errYixiang Zhu; Cheng He; Jovine Bachwenkizi; Zafar Fatmi; Lu Zhou; Cong Liu; Sijin Liu; Haidong Kan; Renjie Chen
err分享
err收藏
Relationships Between Secukinumab Concentrations, Disease Activity, and IL-17A Levels in Psoriasis: A Cross-Sectional Observational StudySecukinumab浓度、疾病活动度与IL-17A水平在银屑病中的关系：一项横断面观察性研究
errdermatology
IF0
err2025-08-05
err0
PREAI
errKouzhu Zhu; Zhou Lu; Lei Cao; Panyu Wu; Yuanbo Huang; Shuo Meng; Yan Wang; Lei Wang
err分享
err收藏
Discovery of N-(1; 3; 4-Thiadiazol-2-yl)amide Derivatives as Uncompetitive Inhibitors of 6-Phosphogluconate DehydrogenaseN-(1; 3; 4-噻二唑-2-基)酰胺衍生物作为6-磷酸葡萄糖酸脱氢酶的非竞争性抑制剂的发现
errJournal of Medicinal Chemistry
IF6.8
err2025-07-31
err0
PREAI
errRong Zhang; Mingming Sun; Xin Xiao; Huiti Li; Lulu Jiang; Jing Chen; Mingzhong Yang; Xueying Yao; Changliang Shan; Lu Zhou
err分享
err收藏
Residue-Selective Inhibitors Discovery via Covalent DNA-Encoded Chemical Libraries with Diverse Warheads通过具有不同弹头的共价DNA编码化学文库发现残基选择性抑制剂
errJOURNAL OF THE AMERICAN CHEMICAL SOCIETY
IF15.6
err2025-04-28
err0
PREAI
errWu, Xinyuan; Pan, Jiayi; Fan, Rufeng; Zhang, Yiwei; Wang, Chao; Wang, Guoliang; Liu, Jiaxiang; Cui, Mengqing; Yue, Jinfeng; Jin, Rui; Duan, Zhiqiang; Zheng, Mingyue; Mei, Lianghe; Zhou, Lu; Ai, Jing
err分享
err收藏
A phosphoglycerate mutase 1 allosteric inhibitor restrains TAM-mediated colon cancer progression
errACTA PHARMACEUTICA SINICA B
IF14.6
err2024-11-01
err0
errOAAI
errWang, Cheng; Zhang, Minghao; Li, Shunyao; Gong, Miaomiao; Luo, Ming-yu; Zhang, Mo-cong; Zou, Jing-Hua; Shen, Ningxiang; Xu, Lu; Lei, Hui-min; Bi, Ling; Zhu, Liang; Wang, Zhengting; Chen, Hong-zhuan; Zhou, Lu; Shen, Ying
err分享
err收藏
Association of gut microbiota with lactose intolerance and coeliac disease: a two-sample Mendelian randomization study
errFRONTIERS IN NUTRITION
IF5.1
err2024-08-06
err1
errOAAI
errHan, Zongze; Ran, Ying; Li, Jiwen; Zhang, Xue; Yang, Hui; Liu, Jiangpeng; Dong, Shijing; Jia, Hao; Yang, Zhen; Li, Yanni; Guo, Liping; Zhou, Simin; Bao, Suriguge; Yuan, Wei; Wang, Bangmao; Zhou, Lu
err分享
err收藏
Cryo-EM structure of human sphingomyelin synthase and its mechanistic implications for sphingomyelin synthesis
errNATURE STRUCTURAL & MOLECULAR BIOLOGY
IF10.1
err2024-02-22
err3
PREAI
errHu, Kexin; Zhang, Qing; Chen, Yang; Yang, Jintong; Xia, Ying; Rao, Bing; Li, Shaobai; Shen, Yafeng; Cao, Mi; Lu, Hongliang; Qin, An; Jiang, Xian-Cheng; Yao, Deqiang; Zhao, Jie; Zhou, Lu; Cao, Yu
err分享
err收藏
The overlooked health impacts of extreme rainfall exposure in 30 East Asian cities
errNATURE SUSTAINABILITY
IF27.1
err2024-02-16
err6
PREAI
errHe, Cheng; Kim, Ho; Hashizume, Masahiro; Lee, Whanhee; Honda, Yasushi; Kim, Satbyul Estella; Guo, Yue Leon; Schneider, Alexandra; Zhu, Yixiang; Zhou, Lu; Chen, Renjie; Kan, Haidong
err分享
err收藏
Flood exposure and pregnancy loss in 33 developing countries33个发展中国家的洪水暴露和妊娠损失
errNATURE COMMUNICATIONS
IF15.7
err2024-01-02
err0
errOAAI
errHe, Cheng; Zhu, Yixiang; Zhou, Lu; Bachwenkizi, Jovine; Schneider, Alexandra; Chen, Renjie; Kan, Haidong
err分享
err收藏
Drug discovery by targeting the protein-protein interactions involved in autophagy
errACTA PHARMACEUTICA SINICA B
IF14.6
err2023-11-01
err11
errOAAI
errXiang, Honggang; Zhou, Mi; Li, Yan; Zhou, Lu; Wang, Renxiao
err分享
err收藏
ABPP-CoDEL: Activity-Based Proteome Profiling-Guided Discovery of Tyrosine-Targeting Covalent Inhibitors from DNA-Encoded Libraries
errJOURNAL OF THE AMERICAN CHEMICAL SOCIETY
IF15.6
err2023-10-19
err8
PREAI
errJiang, Lulu; Liu, Sixiu; Jia, Xinglong; Gong, Qinting; Wen, Xin; Lu, Weiwei; Yang, Jintong; Wu, Xinyuan; Wang, Xuan; Suo, Yanrui; Li, Yilin; Uesugi, Motonari; Qu, Zhi-bei; Tan, Minjia; Lu, Xiaojie; Zhou, Lu
err分享
err收藏
Global warming may significantly increase childhood anemia burden in sub-Saharan Africa
errONE EARTH
IF15.3
err2023-10-01
err2
errOAAI
errZhu, Yixiang; He, Cheng; Gasparrini, Antonio; Vicedo-Cabrera, Ana Maria; Liu, Cong; Bachwenkizi, Jovine; Zhou, Lu; Cheng, Yuexin; Kan, Lena; Chen, Renjie; Kan, Haidong
err分享
err收藏
PGAM1 Inhibition Promotes HCC Ferroptosis and Synergizes with Anti-PD-1 ImmunotherapyPGAM1抑制促进HCC铁死亡并与Anti-PD-1免疫治疗协同作用
errADVANCED SCIENCE
IF14.1
err2023-09-14
err40
errOAAI
errZheng, Yimin; Wang, Yining; Lu, Zhou; Wan, Jinkai; Jiang, Lulu; Song, Danjun; Wei, Chuanyuan; Gao, Chao; Shi, Guoming; Zhou, Jian; Fan, Jia; Ke, Aiwu; Zhou, Lu; Cai, Jiabin
err分享
err收藏

研究方向

药物化学生物学小分子药物设计合成抗代谢靶点药物鞘磷脂合酶2（SMS2）的抑制剂设计合成肿瘤HIF-1α的小分子新靶标确认和机制研究
合作学者
合作期刊
C
Chuan He
H 指数: 161 · 论文数: 979
陈豪 封面图
陈豪 (Hao Chen)
H 指数: 139 · 论文数: 5.6K
樊
樊嘉 (Jia Fan)
H 指数: 126 · 论文数: 1.5K
F
Fadlo R. Khuri
H 指数: 122 · 论文数: 1.1K
H
Haidong Kan
H 指数: 119 · 论文数: 907
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