未登录.png)
分享.png)
收藏分享 收藏 分享 收藏 分享 收藏 分享 收藏 分享 收藏 分享 收藏 Rational Design of the First Dual Agonist at Trace Amine-Associated Receptor 1 and 5-HT2C Receptors Based on Binding Pocket Similarity for the Treatment of Schizophrenia and Alzheimer's Disease-Related Psychosis基于结合口袋相似性的首例双靶点激动剂（Trace Amine-Associated Receptor 1和5-HT2C Receptors）的理性设计，用于治疗精神分裂症和阿尔茨海默病相关精神病
Lu, Jing; Yu, Pengfei; Wang, Yunjie; Dai, Yusen; Wang, Wenyan; Liu, Chunjiao; Dong, Lin; Lei, Hui; Yang, Yifei; Wang, Lin; Zou, Fangxia; Deng, Xuan; Wang, Bingsi; Wei, Shujuan; Ma, Mingxu; Wang, Hongbo; Ye, Liang; Zhang, Jianzhao; Tian, Jingwei 分享 收藏 Rational Design of Dual-Targeted Nanomedicines for Enhanced Vascular Permeability in Low-Permeability Tumors双靶向纳米药物用于低通透性肿瘤增强血管通透性的理性设计Zhu, MS; Liu, QQ; Chen, ZB; Liu, JM; Zhang, ZX; Tian, JW; Wang, XY; Yang, X; Chen, Q; Huang, XL; Zhuang, J 分享 收藏 Design, synthesis, and biological evaluation of novel molecules as potent inhibitors of indoleamine 2,3-dioxygenase 1作为吲哚胺2，3-双加氧酶1的有效抑制剂的新型分子的设计，合成和生物学评估Wei, Shujuan; Zhang, Fuao; Wang, Wenyan; Du, Guangying; Yu, Pengfei; Ye, Liang; Wang, Hongbo; Yang, Yifei; Tian, Jingwei 分享 收藏 LPM682000012, a Synthetic Neuroactive Steroid That Ameliorates Epileptic Seizures by Downregulating the Serpina3n/NF-κB Signaling PathwayZhang, Xiaofan; Ji, Shengmin; Yang, Yue; Sun, Xiaohui; Wang, Hui; Yang, Yifan; Deng, Xuan; Wang, Yunjie; Li, Chunmei; Tian, Jingwei 分享 收藏 Synthesis and evaluation of neuroactive steroids with novel pharmacophore at C-21 let identify a compound with advantageous PK profile and higher EC50 and Emax as PAM on GABAA receptorMa, Mingxu; Xu, Hengwei; Ye, Liang; Li, Chunmei; Zhu, Haibo; Jiang, Wanglin; Wang, Wenyan; Yang, Huijie; Yang, Yingjie; Wang, Yao; Tian, Jingwei 分享 收藏 分享 收藏 Pyruvate dehydrogenase complex E1 subunit a crotonylation modulates cocaine-associated memory through hippocampal neuron activationLi, Hongchun; Liuha, Xiaoyu; Chen, Rong; Xiao, Yuzhou; Xu, Wei; Zhou, Yuanyi; Bai, Lin; Zhang, Jie; Zhao, Yue; Zhao, Ying; Wang, Liang; Qin, Feng; Chen, Yaxing; Han, Shuang; Wei, Qingfan; Li, Shu; Zhang, Dingwen; Bu, Qian; Wang, Xiaojie; Jiang, Linhong; Dai, Yanping; Zhang, Ni; Kuang, Weihong; Qin, Meng; Wang, Hongbo; Tian, Jingwei; Zhao, Yinglan; Cen, Xiaobo 分享 收藏 Novel selective agents for the degradation of AR/AR-V7 to treat advanced prostate cancerYang, Yifei; Lv, Guangyao; Xiu, Ruijuan; Yang, Huijie; Wang, Wenyan; Yu, Pengfei; Zhang, Jianzhao; Ye, Liang; Wang, Hongbo; Tian, Jingwei 分享 收藏 Hippocampal circAnk3 De fi ciency Causes Anxiety-like Behaviors and Social De fi cits by Regulating the miR-7080-3p/IQGAP1 Pathway in MiceHe, Yuman; Jiang, Linhong; Liu, Haxiaoyu; Bu, Qian; Kuang, Weihong; Zhao, Ying; Chen, Yaxing; Zhang, Ni; Xiao, Yuzhou; Li, Shu; Chen, Rong; Han, Shuang; Zhou, Yuanyi; Zhang, Jiamei; Wan, Xuemei; Xu, Rui; Wang, Shaomin; Zhang, Haoluo; Gu, Hui; Wei, Qingfan; Qin, Feng; Zhao, Yue; Li, Hongchun; Wang, Liang; Wang, Xiaojie; Wang, Yonghai; Dai, Yanping; Li, Min; Chen, Yuanyuan; Wang, Hongbo; Tian, Jingwei; Zhao, Yinglan; Cen, Xiaobo 分享 收藏 A novel scaffold long-acting selective estrogen receptor antagonist and degrader with superior preclinical profile against ER plus breast cancerWang, Bingsi; Ma, Mingxu; Dai, Yusen; Yu, Pengfei; Ye, Liang; Wang, Wenyan; Sha, Chunjie; Yang, Huijie; Yang, Yingjie; Zhu, Yunjing; Dong, Lin; Wei, Shujuan; Wang, Linlin; Tian, Jingwei; Wang, Hongbo 分享 收藏 Synthesis and evaluation of piperazinotriazoles. Discovery of a potent and orally bioavailable neurokinin-3 receptor inhibitorYe, Liang; yang, Yifei; Li, Chunmei; Zhang, Jianzhao; Wang, Wenyan; Ma, Mingxu; Xu, Hengwei; Zhang, Wenjing; Zou, Fangxia; Hu, Zhengping; Wang, Hongbo; Tian, Jingwei 分享 收藏 Adverse effects of 21 antidepressants on sleep during acute-phase treatment in major depressive disorder: a systemic review and dose-effect network meta-analysis21种抗抑郁药在重度抑郁症急性期治疗中对睡眠的不良影响: 系统评价和剂量效应网络荟萃分析Zhou, Shuzhe; Li, Pei; Lv, Xiaozhen; Lai, Xuefeng; Liu, Zuoxiang; Zhou, Junwen; Liu, Fengqi; Tao, Yiming; Zhang, Meng; Yu, Xin; Tian, Jingwei; Sun, Feng 分享 收藏 Non-clinical pharmacology and toxicology studies of LPM6690061, a novel 5-hydroxytryptamine (5-HT)2A receptor inverse agonistZhu, Xiaoyin; Yang, Yue; Du, Guangying; Liu, Bin; Yu, Xin; Ye, Liang; Mao, Yutong; Wang, Hongbo; Tian, Jingwei 分享 收藏 
.png){kind=icon}
.png){kind=icon}
.png){kind=icon}
.png)
