Craig W. Lindsley - Publications, H-index & Citations

Craig W. Lindsley

vanderbilt university

86H指数

1.5K论文数

3.1W被引数

收录论文 555

发表时间

Discovery of VU6077564: A Selective M1 Antagonist That Promotes Neurite Outgrowth in Adult Sensory Neurons 发现VU6077564：一种选择性M1拮抗剂，可促进成年感觉神经元轴突生长

ACS Chemical Neuroscience

IF3.9

2026-07-07

OAAI

Tomayo I. Berida; Cayden J. Dodd; Joshua C. Wilkinson; Darrell R. Smith; Sichen Chang; Christopher C. Presley; Li Peng; Snehal Sant; Srinivasan Krishnan; Irene Zagol-Ikapitte; Katherine J. Watson; Analisa Thompson Gray; Alice L. Rodriguez; Hyekyung P. Cho; Carrie K. Jones; Olivier Boutaud; Colleen M. Niswender; Darren W. Engers; Paul Fernyhough; Craig W. Lindsley; Elizabeth S. Childress

Discovery of VU6066098: A Selective and CNS-Penetrant mGlu2 NAM with Robust Antidepressant-; Antipsychotic-; and Procognitive-like Activity in Rodents 发现VU6066098：一种选择性中枢神经系统可穿透的mGlu2 NAM，在啮齿动物中表现出强效的抗抑郁、抗精神病和促认知样活性

ACS Chemical Neuroscience

IF3.9

2026-06-23

OAAI

Jeremy S. Coleman; Rory A. Capstick; Sichen Chang; Derek J. Rios; Michael Bubser; Analisa D. Thompson Gray; Irene Zagol-Ikapitte; Srinivasan Krishnan; Hyekyung P. Cho; Alice L. Rodriguez; Colleen M. Niswender; Olivier Boutaud; Georgina Perez Garcia; Gregory A. Elder; Darren W. Engers; Carrie K. Jones; Craig W. Lindsley

The Nitazene Era: A Critical Turning Point in the Synthetic Opioid Crisis Beyond Fentanyl 尼他泽恩时代：超越芬太尼合成阿片类药物危机的一个关键转折点

Journal of Medicinal Chemistry

IF6.8

2026-04-09

PREAI

Louise F. Dow; Akinwunmi A. Abisogun; Tomayo I. Berida; Srinivasan Krishnan; Upendra Rathnayake; Craig W. Lindsley

Correction to “Phenotypic Screening: A Cornerstone Engine for Discovering Original Anti-Infective Drugs”“表型筛选：发现原始抗感染药物的核心引擎”的修正

Journal of Medicinal Chemistry

IF6.8

2026-02-12

OAAI

Shujing Xu; Mei Wang; Dazhou Shi; Craig W. Lindsley; Meehyein Kim; Yundong Sun; Peng Zhan

Drug Repurposing: Conversion of the Peripherally Restricted HIV Protease Inhibitor Amprenavir to Potent; Selective; and CNS-Penetrant Agonists for the Cannabinoid Receptor 2

Journal of Medicinal Chemistry

IF6.8

2026-02-05

OAAI

Daniel H. Haymer; Renn A. Duncan; Alice L. Rodriguez; Allie Han; Richard J. Lindsay; N. Kithmini Wijesiri; Analisa Thompson Gray; Srinivasan Krishnan; Aidong Qi; Benjamin P. Brown; Olivier Boutaud; Darren W. Engers; Carrie K. Jones; Colleen M. Niswender; Craig W. Lindsley; Aaron M. Bender

Medicinal Chemistry of Next Generation Vaccine Adjuvants

Journal of Medicinal Chemistry

IF6.8

2026-01-29

PREAI

Craig Lindsley; Deepak B. Salunke; Rahul Kumar

Discovery of VU6025733 (AG06827): A Highly Selective; Orally Bioavailable; and Structurally Distinct M4 Muscarinic Acetylcholine Receptor Positive Allosteric Modulator (PAM) with Robust In Vivo Efficacy

ACS Chemical Neuroscience

IF3.9

2026-01-25

OAAI

Alison R. Gregro; Charlotte Park; Madeline F. Long; Logan A. Baker; Katrina A. Bollinger; Anna E. Ringuette; Li Peng; Vincent B. Luscombe; Natasha B. Billard; Alice L. Rodriguez; Colleen M. Niswender; Weimin Peng; Jonathan W. Dickerson; Jerri M. Rook; Jordan O’Neill; Sichen Chang; Harrie C. M. Boonen; Thomas Jensen; Morten S. Thomsen; Thomas M. Bridges; Olivier Boutaud; P. Jeffrey Conn; Darren W. Engers; Craig W. Lindsley; Kayla J. Temple

Discovery of 7-(Pyridin-3-yl)thieno[3; 2-b]pyridine-5-carboxamides as Negative Allosteric Modulators of Metabotropic Glutamate Receptor Subtype 5

ACS Chemical Neuroscience

IF3.9

2026-01-25

OAAI

Scott H. Henderson; Anna E. Ringuette; David L. Whomble; Rory A. Capstick; Alexa E. Richardson; Mallory A. Maurer; Natasha B. Billard; Xia Lei; Joshua C. Wilkinson; Sri H. Kethanapalli; Hyekyung P. Cho; Alice L. Rodriguez; Colleen M. Niswender; Weimin Peng; Jerri M. Rook; Sichen Chang; Anna L. Blobaum; Olivier Boutaud; Andrew S. Felts; P. Jeffrey Conn; Craig W. Lindsley; Kayla J. Temple

Call for Papers: Medicinal Chemistry and Pharmacology of Antiviral Drugs

Journal of Medicinal Chemistry

IF6.8

2026-01-22

OAAI

Peng Zhan; Stefano Alcaro; Scott Pegan; Craig W. Lindsley; Jayanta Haldar; Kelly Chibale; Christa E. Müller

Discovery of VU6083859, a TAOK1 Selective Inhibitor, and VU6080195, a pan-TAOK Activator 发现VU6083859，一种TAOK1选择性抑制剂，以及VU6080195，一种泛TAOK激活剂

ACS Chemical Neuroscience

IF3.9

2026-01-01

OAAI

Schultz, Daniel C.; Parr, Lauren C.; Sweet, Hunter; Lamb, Sean; Engers, Julie L.; Napier, Nathaniel C.; McKinnie, Hallie G.; Whomble, David; Kramlinger, Valerie; Boutaud, Olivier; Lindsley, Craig W.

Phenotypic Screening: A Cornerstone Engine for Discovering Original Anti-Infective Drugs

JOURNAL OF MEDICINAL CHEMISTRY

IF6.8

2025-12-25

PREAI

Xu, Shujing; Wang, Mei; Shi, Dazhou; Lindsley, Craig W.; Kim, Meehyein; Sun, Yundong; Zhan, Peng

Recent Advances in Long-Acting Antiviral Agents: Innovations in Design and Strategies for Extended Duration

JOURNAL OF MEDICINAL CHEMISTRY

IF6.8

2025-12-01

PREAI

Wang, Shuo; Ma, Feiyue; Lindsley, Craig W.; Xu, Shujing; Liu, Xinyong; Zhan, Peng

Discovery of VU6052254: A Novel; Potent M1 Positive Allosteric Modulator VU6052254的发现：一种新型的强效M1正向别构调节剂

ACS Chemical Neuroscience

IF3.9

2025-11-26

OAAI

Julie L. Engers; Joseph D. Bungard; Christopher C. Presley; Irene Zagol-Ikapitte; Katherine J. Watson; Sichen Chang; Colin O’Carroll; P. Markus Dey; Ethan S. Burstein; Jonathan W. Dickerson; Analisa Thompson Gray; Michael Bubser; Jerri M. Rook; Hyekyung P. Cho; Valerie M. Kramlinger; Olivier Boutaud; Carrie K. Jones; P. Jeffrey Conn; Darren W. Engers; Craig W. Lindsley

Structural Biology Enabling Drug Discovery 结构生物学赋能药物发现

Journal of Medicinal Chemistry

IF6.8

2025-11-19

OAAI

David E. Heppner; Simone V. Bigi-Botterill; Andrew P. Riley; Kelly Chibale; Craig W. Lindsley

Optimization of Selective and CNS Penetrant Alkyne-Based TREK Inhibitors: The Discovery and Characterization of ONO-9517601 (VU6022856) and ONO-7927846 (VU6024391)

JOURNAL OF MEDICINAL CHEMISTRY

IF6.8

2025-10-01

PREAI

Tanaka, Motoyuki; Sekioka, Yoko; Hashimoto, Gakuji; Mori, Takahiro; Shono, Tomoyuki; Isaji, Yuuki; Hisaichi, Katsuya; Childress, Elizabeth S.; Bollinger, Sean; Schmitt, Joza A.; Chopko, Trevor C.; Garrison, Aaron T.; Perry, Charles K.; Chronister, Keagan; Kramer, Meghan; Chang, Sichen; Watson, Katherine J.; Dickerson, Jonathan W.; Bubser, Michael; Rook, Jerri M.; Jones, Carrie K.; Boutaud, Olivier; Bridges, Thomas M.; Denton, Jerod S.; Engers, Darren W.; Kurata, Haruto; Lindsley, Craig W.

Investigating the role of rostral pedunculopontine nucleus M4 receptors in motor deficits and dyskinesia in hemiparkinsonian rats 研究延脑被盖网状核M4受体在偏侧帕金森病大鼠运动障碍和运动过多中的作用

Behavioural Brain Research

IF2.3

2025-09-24

PREAI

Nicole E. Chambers; Annique McLune; Michael Coyle; Ashley Centner; Jordan Sergio; Isabella Del Priore; Kathryn Lanza; Craig W. Lindsley; P. Jeffrey Conn; Christopher Bishop

Cryo-EM reveals an extrahelical allosteric binding site at the M5 mAChR 冷冻电镜揭示了M5 mAChR上的一种存在于螺旋之外的别构结合位点

Nature Communications

IF15.7

2025-07-31

OAAI

Wessel A. C. Burger; Jesse I. Mobbs; Bhavika Rana; Jinan Wang; Keya Joshi; Patrick R. Gentry; Mahmuda Yeasmin; Hariprasad Venugopal; Aaron M. Bender; Craig W. Lindsley; Yinglong Miao; Arthur Christopoulos; Celine Valant; David M. Thal

Discovery of ONO-TR-772 (VU6018042): A Highly Selective and CNS Penetrant TREK Inhibitor in Vivo Tool Compound ONO-TR-772 (VU6018042)的发现：一种在体工具化合物，具有高度选择性且能穿透CNS的TREK抑制剂

ACS MEDICINAL CHEMISTRY LETTERS

IF4

2025-04-28

OAAI

Tanaka, M; Mori, T; Hashimoto, G; Mitsui, K; Kishi, A; Childress, ES; Bollinger, SR; Chopko, TC; Bridges, TM; Stafford, DG; Huang, ZP; Wolf, MA; Engers, DW; Denton, JS; Kurata, H; Lindsley, CW

Total Synthesis and Pharmacological Evaluation of Phochrodines A-C

JOURNAL OF NATURAL PRODUCTS

IF3.6

2025-04-01

OAAI

Bouchard, Jacob L.; Chang, Sichen; Krishnan, Srinivasan; Presley, Christopher C.; Boutaud, Olivier; Schley, Nathan D.; Engers, Darren W.; Engers, Julie L.; Lindsley, Craig W.; Bender, Aaron M.

Discovery of Thieno[3,2-b]pyridine-5-carboxamide and 2,3-Difluorobenzamide Negative Allosteric Modulators of Metabotropic Glutamate Receptor Subtype 5

ACS MEDICINAL CHEMISTRY LETTERS

IF4

2025-04-01

OAAI

Crocker, Katherine E.; Henderson, Scott H.; Capstick, Rory A.; Whomble, David L.; Bender, Aaron M.; Felts, Andrew S.; Han, Changho; Engers, Julie L.; Billard, Natasha B.; Maurer, Mallory A.; Cho, Hyekyung P.; Rodriguez, Alice L.; Niswender, Colleen M.; O'Neill, Jordan; Watson, Katherine J.; Chang, Sichen; Blobaum, Anna L.; Boutaud, Olivier; Peng, Weimin; Rook, Jerri M.; Conn, P. Jeffrey; Lindsley, Craig W.; Temple, Kayla J.

研究方向