John R. Huguenard - Publications, H-index & Citations

John R. Huguenard

Department of Neurology and Neurological Sciences

85H指数

292论文数

2.9W被引数

收录论文 49

发表时间

Author Correction: Maturation and circuit integration of transplanted human cortical organoids 作者更正：移植人皮质类器官的成熟与回路整合

Nature

IF48.5

2026-08-03

OAAI

Omer Revah; Felicity Gore; Kevin W. Kelley; Jimena Andersen; Noriaki Sakai; Xiaoyu Chen; Min-Yin Li; Fikri Birey; Xiao Yang; Nay L. Saw; Samuel W. Baker; Neal D. Amin; Shravanti Kulkarni; Rachana Mudipalli; Bianxiao Cui; Seiji Nishino; Gerald A. Grant; Juliet K. Knowles; Mehrdad Shamloo; John R. Huguenard; Karl Deisseroth; Sergiu P. Paşca

Beyond seizure control: Identifying deficits in cognitive networks in absence epilepsy 超越癫痫控制：识别失神癫痫中认知网络的缺陷

Science Advances

IF12.5

2026-05-13

OAAI

Gil Vantomme; Gabrielle Devienne; Jacob M. Hull; John R. Huguenard

Juvenile-to-adult refinement of thalamic reticular circuits via LRRTM3 enables high-resolution sensory encoding 丘脑网状核回路从幼年到成年的精细化修饰通过LRRTM3实现高分辨率感觉编码

Neuron

IF15

2026-02-17

PREAI

Dongsu Lee; Kyung Ah Han; Hyeonyeong Jeong; Go Eun Ha; Hyeongjin Lee; Beom Soo Kim; Chanmi Park; Yao Piao; Haeun Lee; Joon Kim; Taek Han Yoon; Seungjoon Kim; Byeongchan Kim; Jungsu Shin; Yujin Cho; Sunghyun Kang; Han-Eol Park; Ji Won Um; Chang Ho Sohn; John R. Huguenard

Disrupted Development of the mPFC-Thalamic Circuit in Shank3–/– mice, an autism-associated model Shank3–/–小鼠中mPFC-丘脑回路的发育中断，一种自闭症相关模型

Molecular Psychiatry

IF10.1

2025-12-16

PREAI

Gabrielle Devienne; Gil Vantomme; John R. Huguenard

Reticular thalamic hyperexcitability drives autism spectrum disorder behaviors in the Cntnap2 model of autism 丘脑网状核的高兴奋性驱动自闭症模型Cntnap2中的自闭症谱系障碍行为

Science Advances

IF12.5

2025-08-20

OAAI

Sung-Soo Jang; Fuga Takahashi; John R. Huguenard

Adult Gene Therapy for Epilepsy in a Model of Angelman Syndrome: Hope or Hype?

EPILEPSY CURRENTS

IF6.3

2023-08-07

OAAI

Huguenard, John R.

A CMOS-based highly scalable flexible neural electrode interface

SCIENCE ADVANCES

IF12.5

2023-06-09

OAAI

Zhao, Eric T.; Hull, Jacob M.; Hemed, Nofar Mintz; Ulusan, Hasan; Bartram, Julian; Zhang, Anqi; Wang, Pingyu; Pham, Albert; Ronchi, Silvia; Huguenard, John R.; Hierlemann, Andreas; Melosh, Nicholas A.

Prefrontal PV interneurons facilitate attention and are linked to attentional dysfunction in a mouse model of absence epilepsy

ELIFE

IF0

2023-04-04

OAAI

Ferguson, Brielle; Glick, Cameron; Huguenard, John R.

Loss of Rai1 enhances hippocampal excitability and epileptogenesis in mouse models of Smith-Magenis syndrome 在smith-magenis综合征的小鼠模型中，Rai1的缺失会增强海马的兴奋性和癫痫发生。

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2022-10-18

OAAI

Chang, Ya-Ting; Kowalczyk, Max; Fogerson, P. Michelle; Lee, Yu-Ju; Haque, Minza; Adams, Eliza L.; Wang, David C.; DeNardo, Laura A.; Tessier-Lavigne, Marc; Huguenard, John R.; Luo, Liqun; Huang, Wei-Hsiang

Precise spatiotemporal control of voltage-gated sodium channels by photocaged saxitoxin (vol 12, 4171, 2021)

NATURE COMMUNICATIONS

IF15.7

2022-04-21

OAAI

Elleman, Anna V.; Devienne, Gabrielle; Makinson, Christopher D.; Haynes, Allison L.; Huguenard, John R.; Du Bois, J.

Precise spatiotemporal control of voltage-gated sodium channels by photocaged saxitoxin

NATURE COMMUNICATIONS

IF15.7

2021-07-07

OAAI

Elleman, Anna, V; Devienne, Gabrielle; Makinson, Christopher D.; Haynes, Allison L.; Huguenard, John R.; Du Bois, J.

Development and validation of a potent and specific inhibitor for the CLC-2 chloride channel CLC-2氯离子通道强效特异性抑制剂的开发与验证

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2020-12-04

OAAI

Koster, Anna K.; Reese, Austin L.; Kuryshev, Yuri; Wen, Xianlan; McKiernan, Keri A.; Gray, Erin E.; Wu, Caiyun; Huguenard, John R.; Maduke, Merritt; Du Bois, J.

Perspective: Is Cortical Hyperexcitability the Only Path to Generalized Absence Epilepsy?

EPILEPSY CURRENTS

IF6.3

2020-10-14

OAAI

Huguenard, John R.

Neuronal defects in a human cellular model of 22q11.2 deletion syndrome 22 q11.2缺失综合征的人类细胞模型中的神经元缺陷

NATURE MEDICINE

IF50

2020-09-28

116

OAAI

Khan, Themasap A.; Revah, Omer; Gordon, Aaron; Yoon, Se-Jin; Krawisz, Anna K.; Goold, Carleton; Sun, Yishan; Kim, Chul Hoon; Tian, Yuan; Li, Min-Yin; Schaepe, Julia M.; Ikeda, Kazuya; Amin, Neal D.; Sakai, Noriaki; Yazawa, Masayuki; Kushan, Leila; Nishino, Seiji; Porteus, Matthew H.; Rapoport, Judith L.; Bernstein, Jonathan A.; O'Hara, Ruth; Bearden, Carrie E.; Hallmayer, Joachim F.; Huguenard, John R.; Geschwind, Daniel H.; Dolmetsch, Ricardo E.; Pasca, Sergiu P.

Nonlinearities between inhibition and T-type calcium channel activity bidirectionally regulate thalamic oscillations

ELIFE

IF0

2020-09-09

OAAI

Lu, Adam C.; Lee, Christine Kyuyoung; Kleiman-Weiner, Max; Truong, Brian; Wang, Megan; Huguenard, John R.; Beenhakker, Mark P.

Current Controversy: Spikes, Bursts, and Synchrony in Generalized Absence Epilepsy: Unresolved Questions Regarding Thalamocortical Synchrony in Absence Epilepsy

EPILEPSY CURRENTS

IF6.3

2019-04-08

OAAI

Huguenard, John

Reliability of human cortical organoid generation 人类皮质类器官生成的可靠性

NATURE METHODS

IF32.1

2018-12-20

317

OAAI

Yoon, Se-Jin; Elahi, Lubayna S.; Pasca, Anca M.; Marton, Rebecca M.; Gordon, Aaron; Revah, Omer; Miura, Yuki; Walczak, Elisabeth M.; Holdgate, Gwendolyn M.; Fan, H. Christina; Huguenard, John R.; Geschwind, Daniel H.; Pasca, Sergiu P.

Shank and Zinc Mediate an AMPA Receptor Subunit Switch in Developing Neurons

FRONTIERS IN MOLECULAR NEUROSCIENCE

IF3.8

2018-11-09

OAAI

Ha, Huong T. T.; Leal-Ortiz, Sergio; Lalwani, Kriti; Kiyonaka, Shigeki; Hamachi, Itaru; Mysore, Shreesh P.; Montgomery, Johanna M.; Garner, Craig C.; Huguenard, John R.; Kim, Sally A.

Regulation of Thalamic and Cortical Network Synchrony by Scn8a

NEURON

IF15

2017-03-01

OAAI

Makinson, Christopher D.; Tanaka, Brian S.; Sorokin, Jordan M.; Wong, Jennifer C.; Christian, Catherine A.; Goldin, Alan L.; Escayg, Andrew; Huguenard, John R.

Bidirectional Control of Generalized Epilepsy Networks via Rapid Real-Time Switching of Firing Mode

NEURON

IF15

2017-01-01

OAAI

Sorokin, Jordan M.; Davidson, Thomas J.; Frechette, Eric; Abramian, Armen M.; Deisseroth, Karl; Huguenard, John R.; Paz, Jeanne T.

研究方向