Jyotika Varshney - Publications, H-index & Citations

Jyotika Varshney

verisim life inc, 1 sansome street, suite 3500, san francisco, california 94104, united states

16H指数

60论文数

707被引数

收录论文 21

发表时间

AI-Driven Integration of Transcriptomics; Quantum Mechanics; and Physiology for Predicting Drug-Induced Liver Injury in Data-Limited Scenarios AI驱动的转录组学、量子力学和生理学的整合，用于在数据有限场景下预测药物诱导的肝损伤

Chemical Research in Toxicology

IF3.8

2025-07-02

PREAI

Roshan Bhave; Babatunde Bello; Divesh Bhatt; Joseph Machulcz; Jacqueline A. R. Shea; Maksim Khotimchenko; Weida Tong; Szczepan W. Baran; Jyotika Varshney

Techniques for Validating CRISPR Changes Using RNA-Sequencing Data 利用RNA测序数据验证CRISPR基因编辑变化的技术

GENES

IF2.8

2025-03-24

OAAI

Rathe, Susan K.; Marko, Tracy A.; Edwards, Elizabeth N.; Ridder, Paige Hazelton; Varshney, Jyotika; Williams, Kyle B.; Johnson, James E.; Moriarity, Branden S.

AI/ML-Driven in Silico Identification of Blood-Brain Barrier Permeable Compounds

DRUG AND ALCOHOL DEPENDENCE

IF3.6

2024-07-01

PREAI

Khotimchenko, Maksim; Chakravarty, Kaushik; Miller, Courtney; Bundey, Yogesh; Bhave, Roshan; Baran, Szczepan; Varshney, Jyotika

An AI Approach to Generating MIDD Assets Across the Drug Development Continuum

AAPS JOURNAL

IF3.7

2023-07-10

OAAI

Barrett, Jeffrey S.; Goyal, Rahul K.; Gobburu, Jogarao; Baran, Szczepan; Varshney, Jyotika

Integrated Quantum Mechanical and Machine Learning Methods Enable Scalable and General pKa Prediction for Pharmacokinetic Modeling

FASEB JOURNAL

IF4.2

2022-05-13

PREAI

Walden, Daniel M.; Bundey, Yogesh; Brunk, Nicholas E.; Khotimehenko, Maksim; Hou, Hypatia; Chakravarty, Kaushik; Hixon, Mark S.; Varshney, Jyotika

AI/ML-driven simulation of the skin retention of opioid analgesics following topical administration in normal skin and cutaneous lesions

FASEB JOURNAL

IF4.2

2022-05-13

PREAI

Khotimchenko, Maksim; Antontsev, Victor; Chakravarty, Kaushik; Hou, Hypatia; Varshney, Jyotika

In Silico Development of Combinatorial Therapeutic Approaches Targeting Key Signaling Pathways in Metabolic Syndrome

PHARMACEUTICAL RESEARCH

IF4.3

2022-03-21

PREAI

Khotimchenko, Maksim; Brunk, Nicholas E.; Hixon, Mark S.; Walden, Daniel M.; Hou, Hypatia; Chakravarty, Kaushik; Varshney, Jyotika

Driving success in personalized medicine through Al-enabled computational modeling 通过启用Al的计算建模推动个性化医疗的成功

DRUG DISCOVERY TODAY

IF7.5

2021-06-01

PREAI

Chakravarty, Kaushik; Antontsev, Victor; Bundey, Yogesh; Varshney, Jyotika

A hybrid modeling approach for assessing mechanistic models of small molecule partitioning in vivo using a machine learning-integrated modeling platform

SCIENTIFIC REPORTS

IF3.9

2021-05-27

OAAI

Antontsev, Victor; Jagarapu, Aditya; Bundey, Yogesh; Hou, Hypatia; Khotimchenko, Maksim; Walsh, Jason; Varshney, Jyotika

Effects of Magnesium, Calcium, and Aluminum Chelation on Fluoroquinolone Absorption Rate and Bioavailability: A Computational Study

PHARMACEUTICS

IF5.5

2021-04-21

OAAI

Walden, Daniel M.; Khotimchenko, Maksim; Hou, Hypatia; Chakravarty, Kaushik; Varshney, Jyotika

Accelerated Repurposing and Drug Development of Pulmonary Hypertension Therapies for COVID-19 Treatment Using an AI-Integrated Biosimulation Platform

MOLECULES

IF4.6

2021-03-29

OAAI

Chakravarty, Kaushik; Antontsev, Victor G.; Khotimchenko, Maksim; Gupta, Nilesh; Jagarapu, Aditya; Bundey, Yogesh; Hou, Hypatia; Maharao, Neha; Varshney, Jyotika

In Silico Simulation of the Systemic Drug Exposure Following the Topical Application of Opioid Analgesics in Patients with Cutaneous Lesions

PHARMACEUTICS

IF5.5

2021-02-21

OAAI

Khotimchenko, Maksim; Antontsev, Victor; Chakravarty, Kaushik; Hou, Hypatia; Varshney, Jyotika

Molecular Simulation and Statistical Learning Methods toward Predicting Drug-Polymer Amorphous Solid Dispersion Miscibility, Stability, and Formulation Design

MOLECULES

IF4.6

2021-01-01

OAAI

Walden, Daniel M.; Bundey, Yogesh; Jagarapu, Aditya; Antontsev, Victor; Chakravarty, Kaushik; Varshney, Jyotika

Entering the era of computationally driven drug development

DRUG METABOLISM REVIEWS

IF3.8

2020-02-21

PREAI

Maharao, Neha; Antontsev, Victor; Wright, Matthew; Varshney, Jyotika

RNA sequencing based analysis of transposon-induced tumors reveals novel insights into cancer pathogenesis and progression

CANCER RESEARCH

IF16.6

2018-07-01

PREAI

Camilleri, Emily T.; Beckmann, Pauli J.; Larson, Jon D.; Kurata, Morito; Shu, Jingmin; Pope, Emily; Hudson, Wendy A.; Temiz, Nuri A.; Rathe, Susan K.; LaRue, Rebecca S.; Sarver, Anne E.; Scott, Milcah C.; Varshney, Jyotika; Modiano, Jaime F.; Moriarity, Branden S.; Sarver, Aaron L.; Seshagiri, Somasekar; Largaespada, David A.

Comparative Transcriptome Analysis Quantifies Immune Cell Transcript Levels, Metastatic Progression, and Survival in Osteosarcoma

CANCER RESEARCH

IF16.6

2018-01-15

OAAI

Scott, Milcah C.; Temiz, Nuri A.; Sarver, Anne E.; LaRue, Rebecca S.; Rathe, Susan K.; Varshney, Jyotika; Wolf, Natalie K.; Moriarity, Branden S.; O'Brien, Timothy D.; Spector, Logan G.; Largaespada, David A.; Modiano, Jaime F.; Subramanian, Subbaya; Sarver, Aaron L.

Slit-Robo GTPase-Activating Protein 2 as a metastasis suppressor in osteosarcoma

SCIENTIFIC REPORTS

IF3.9

2016-12-14

OAAI

Marko, Tracy A.; Shamsan, Ghaidan A.; Edwards, Elizabeth N.; Hazelton, Paige E.; Rathe, Susan K.; Cornax, Ingrid; Overn, Paula R.; Varshney, Jyotika; Diessner, Brandon J.; Moriarity, Branden S.; O'Sullivan, M. Gerard; Odde, David J.; Largaespada, David A.

The miR-17-92 microRNA cluster plays a crucial role in osteosarcoma progression

CANCER RESEARCH

IF16.6

2016-07-15

PREAI

Varshney, Jyotika; Slipek, Nicholas J.; Osborne, John; Chang, Adrian; Sarver, Anne E.; Cornax, Ingrid; O'Sullivan, Gerry M.; Subramanian, Subbaya; Largaespada, David A.

Aberrant Retinoblastoma (RB)-E2F Transcriptional Regulation Defines Molecular Phenotypes of Osteosarcoma

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2015-11-01

OAAI

Scott, Milcah C.; Sarver, Aaron L.; Tomiyasu, Hirotaka; Cornax, Ingrid; Van Etten, Jamie; Varshney, Jyotika; O'Sullivan, M. Gerard; Subramanian, Subbaya; Modiano, Jaime F.

MicroRNAs as potential target in human bone and soft tissue sarcoma therapeutics MicroRNAs作为人骨和软组织肉瘤治疗的潜在靶点

FRONTIERS IN MOLECULAR BIOSCIENCES

IF4

2015-06-17

OAAI

Varshney, Jyotika; Subramanian, Subbaya

研究方向