logo
科言猫学术研究的AI总结
language
手机端手机端
  • Phone Feature微信小程序
简体中文简体中文
notice消息通知
博客博客
delete
arrow
返回
M

Matthew D. Disney

the herbert wertheim uf scripps institute for biomedical innovation & technology

64H指数
268论文数
1.5W被引数
收录论文 134
发表时间
logo
Drug-Derived Tetrahydropyrazines for Late-Stage α- and β-Functionalization of Piperazine-Based Pharmaceuticals源自药物的四氢吡嗪衍生物用于哌嗪基药物分子的晚期阶段α-和β-官能化
errAngewandte Chemie-International Edition
IF16.9
err2026-09-03
err0
PREAI
errSoichiro Mori; Cunyuan Zhao; Tenghui Wang; Yuankai Wang; Yu Nishio; Matthew D. Disney; Masayuki Wasa
err分享
err收藏
Small-Molecule Degradation of the MicroRNA-21 Precursor Rescues Pathogenic Pathways in Cellular Models of Fibrosis小分子降解微RNA-21前体可挽救纤维化细胞模型中的致病通路
errACS Chemical Biology
IF3.8
err2026-05-18
err0
PREAI
errTenghui Wang; Xueyi Yang; Yeongju Lee; Jin H. Song; Jessica L. Childs-Disney; Joe G.N. Garcia; Matthew D. Disney
err分享
err收藏
An RNA-Focused DNA-Encoded Library Platform for Discovering Ligands of Pathogenic r(G4C2)exp RNA一种以RNA为重点的DNA编码库平台，用于发现病原性r(G4C2)exp RNA的配体
errACS Chemical Biology
IF3.8
err2026-05-07
err0
PREAI
errXueyi Yang; Amirhossein Taghavi; Yoshihiro Akahori; Martina Pedrini; Takahiro Ishii; Matthew D. Disney
err分享
err收藏
Mechanistically Defined Epoxide- and Aziridine-2-carboxamide Electrophiles Enable Stereoselective Covalent Ribonucleic Acid Modulation机制定义的环氧化物和氮杂环丙烷-2-羧酰胺亲电试剂实现立体选择性共价核糖核酸修饰
errJournal of the American Chemical Society
IF15.6
err2026-04-16
err0
PREAI
errChungen Li; Xueyi Yang; Jingsong Shan; Kyle A. Dickerson; Noah A. Springer; Nikhil C. Munshi; Robert T. Batey; Matthew D. Disney
err分享
err收藏
Chemical Tagging of N-Alkylamine-Containing Natural Products and Pharmaceuticals through C(sp3)–H Functionalization通过C(sp3)–H官能化对含N-烷基胺结构的天然产物和药物进行化学标记
errJournal of the American Chemical Society
IF15.6
err2025-11-14
err0
PREAI
errYuankai Wang; Cunyuan Zhao; Tenghui Wang; Andrew Steele; Manas Joshi; Soichiro Mori; Abhishek Chatterjee; Ben Shen; Matthew D. Disney; Masayuki Wasa
err分享
err收藏
Unbiased RNA Degrader Identification Uncovers an LC3B-Recruiting Chimera for COL15A1 mRNA Degradation无偏RNA降解剂鉴定发现一种招募LC3B的嵌合体用于COL15A1 mRNA降解
errJOURNAL OF THE AMERICAN CHEMICAL SOCIETY
IF15.6
err2025-11-01
err0
PREAI
errSu, Xiaoxuan; Tong, Yuquan; Zanon, Patrick R. A.; Wang, Jielei; Tanaka, Toru; Childs-Disney, Jessica L.; Disney, Matthew D.
err分享
err收藏
A Live-Cell NanoBRET Assay to Monitor RNA-Protein Interactions and Their Inhibition by Small Molecules一种活细胞NanoBRET assay，用于监测RNA-蛋白质相互作用及其被小分子抑制的情况
errACS CENTRAL SCIENCE
IF10.4
err2025-09-01
err0
PREAI
errShan, Jingsong; Taghavi, Amirhossein; Caine, Elizabeth A.; Sekioka, Ryuichi; Rajchin, Veronika; Burke, James M.; Watkins, J. Monty; Childs-Disney, Jessica L.; Disney, Matthew D.
err分享
err收藏
Design of an Orally Bioavailable Small Molecule That Modulates the Microtubule-Associated Protein Tau’s Pre-mRNA Splicing一种可口服生物利用的小分子设计，该分子能够调节微管相关蛋白Tau的pre-mRNA剪接
errACS Chemical Biology
IF3.8
err2025-06-23
err0
errOAAI
errPeiyuan Zhang; Amirhossein Taghavi; Masahito Abe; Haruo Aikawa; Yoshihiro Akahori; Jonathan L. Chen; Yuquan Tong; Jared T. Baisden; Michael D. Cameron; Jessica L. Childs-Disney; Matthew D. Disney
err分享
err收藏
Mapping small molecule-RNA binding sites via Chem-CLIP synergized with capillary electrophoresis and nanopore sequencing通过化学交联免疫沉淀（Chem-CLIP）与毛细管电泳和纳米孔测序协同定位小分子-RNA结合位点
errNUCLEIC ACIDS RESEARCH
IF13.1
err2025-03-28
err0
errOAAI
errYang, Xueyi; Wang, Jielei; Springer, Noah A.; Zanon, Patrick R. A.; Jia, Yilin; Su, Xiaoxuan; Disney, Matthew D.
err分享
err收藏
The Druggable Transcriptome Project: From Chemical Probes to Precision Medicines可成药转录组项目：从化学探针到精准药物
errBIOCHEMISTRY
IF3
err2025-03-25
err0
PREAI
errDisney, Matthew D.
err分享
err收藏
The evolution and application of RNA-focused small molecule libraries
errRSC CHEMICAL BIOLOGY
IF3.1
err2025-01-01
err0
errOAAI
errTaghavi, Amirhossein; Springer, Noah A.; Zanon, Patrick R. A.; Li, Yanjun; Li, Chenglong; Childs-Disney, Jessica L.; Disney, Matthew D.
err分享
err收藏
Development of MAPT S305 mutation human iPSC lines exhibiting elevated 4R tau expression and functional alterations in neurons and astrocytes
errCELL REPORTS
IF6.9
err2024-12-01
err0
PREAI
errBowles, Kathryn R.; Pedicone, Chiara; Pugh, Derian A.; Oja, Laura-Maria; Sousa, Filipa H.; Keavey, Lois K.; Fulton-Howard, Brian; Weitzman, Sarah A.; Liu, Yiyuan; Chen, Jonathan L.; Disney, Matthew D.; Goate, Alison M.
err分享
err收藏
Targeting RNA with small molecules, from RNA structures to precision medicines: IUPHAR review: 40用小分子靶向RNA，从RNA结构到精密药物: IUPHAR综述: 40
errBRITISH JOURNAL OF PHARMACOLOGY
IF7.7
err2024-09-03
err1
PREAI
errTong, Yuquan; Childs-Disney, Jessica L.; Disney, Matthew D.
err分享
err收藏
Transcriptome-Wide, Unbiased Profiling of Ribonuclease Targeting Chimeras
errJOURNAL OF THE AMERICAN CHEMICAL SOCIETY
IF15.6
err2024-07-24
err0
PREAI
errTong, Yuquan; Su, Xiaoxuan; Rouse, Warren; Childs-Disney, Jessica L.; Taghavi, Amirhossein; Zanon, Patrick R. A.; Kovachka, Sandra; Wang, Tenghui; Moss, Walter N.; Disney, Matthew D.
err分享
err收藏
Heterobifunctional small molecules to modulate RNA function
errTRENDS IN PHARMACOLOGICAL SCIENCES
IF19.9
err2024-05-01
err2
PREAI
errKovachka, Sandra; Tong, Yuquan; Childs-Disney, Jessica L.; Disney, Matthew D.
err分享
err收藏
Decreasing the intrinsically disordered protein α-synuclein levels by targeting its structured mRNA with a ribonuclease- targeting chimera通过靶向核糖核酸酶的嵌合体靶向其结构化mRNA来降低内在无序的蛋白质 α-突触核蛋白水平
errPROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
IF9.1
err2024-01-05
err8
errOAAI
errTong, Yuquan; Zhang, Peiyuan; Yang, Xueyi; Liu, Xiaohui; Zhang, Jie; Grudniewska, Magda; Jung, Ikrak; Abegg, Daniel; Liu, Jun; Childs-Disney, Jessica L.; Gibaut, Quentin M. R.; Haniff, Hafeez S.; Adibekian, Alexander; Mouradian, M. Maral; Disney, Matthew D.
err分享
err收藏
Optimization of a Protein-Targeted Medicine into an RNA-Specific Small Molecule
errACS CHEMICAL BIOLOGY
IF3.8
err2023-10-23
err4
PREAI
errMeyer, Samantha M.; Tanaka, Toru; Taghavi, Amirhossein; Baisden, Jared T.; Grefe, Maison; Disney, Matthew D.
err分享
err收藏
Roadmap for C9ORF72 in Frontotemporal Dementia and Amyotrophic Lateral Sclerosis: Report on the C9ORF72 FTD/ALS SummitC9ORF72治疗额颞叶痴呆和肌萎缩性侧索硬化症的路线图: C9ORF72 FTD/ALS峰会报告
errNEUROLOGY AND THERAPY
IF4.8
err2023-10-17
err14
errOAAI
errSattler, Rita; Traynor, Bryan J.; Robertson, Janice; Van den Bosch, Ludo; Barmada, Sami J.; Svendsen, Clive N.; Disney, Matthew D.; Gendron, Tania F.; Wong, Philip C.; Turner, Martin R.; Boxer, Adam; Babu, Suma; Benatar, Michael; Kurnellas, Michael; Rohrer, Jonathan D.; Donnelly, Christopher J.; Bustos, Lynette M.; Van Keuren-Jensen, Kendall; Dacks, Penny A.; Sabbagh, Marwan N.
err分享
err收藏
Altering the Cleaving Effector in Chimeric Molecules that Target RNA Enhances Cellular Selectivity改变靶向RNA的嵌合分子中的切割效应增强细胞选择性
errACS CHEMICAL BIOLOGY
IF3.8
err2023-10-12
err7
PREAI
errSuresh, Blessy M.; Tong, Yuquan; Abegg, Daniel; Adibekian, Alexander; Childs-Disney, Jessica L.; Disney, Matthew D.
err分享
err收藏
Transcriptome-Wide Studies of RNA-Targeted Small Molecules Provide a Simple and Selective r(CUG)exp Degrader in Myotonic Dystrophy
errACS CENTRAL SCIENCE
IF10.4
err2023-06-26
err7
errOAAI
errGibaut, Quentin M. R.; Bush, Jessica A.; Tong, Yuquan; Baisden, Jared T.; Taghavi, Amirhossein; Olafson, Hailey; Yao, Xiyuan; Childs-Disney, Jessica L.; Wang, Eric T.; Disney, Matthew D.
err分享
err收藏

研究方向

暂时未获取到该数据
合作学者
合作期刊
J
John Q. Trojanowski
H 指数: 255 · 论文数: 1.8K
D
Dennis W. Dickson
H 指数: 218 · 论文数: 2.3K
B
Bruce L. Miller
H 指数: 201 · 论文数: 2.1K
A
Anthony S. Fauci
H 指数: 185 · 论文数: 1.1K
F
Francis S. Collins
H 指数: 182 · 论文数: 839
查看更多