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H

H. T. Marc Timmers

dkfz and medical center-university of freiburg

55H指数
172论文数
9.7K被引数
收录论文 88
发表时间
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Menin-MLL inhibitors enhance JUND activity in MLLr leukemic cells contributing to tumorigenesis and therapy resistanceMenin-MLL抑制剂增强MLL重排白血病细胞中JUND活性，促进肿瘤发生和耐药性产生
errBlood
IF23.1
err2026-07-01
err0
PREAI
errEzgi Ozyerli-Goknar; Sheikh Nizamuddin; Viktor Fetsch; Martin L. Biniossek; Alina Hartmann; Florian Perner; Gerard M. McGeehan; Scott A. Armstrong; Robert Zeiser; H.T.Marc Timmers
err分享
err收藏
Development of High-Affinity CHD1 Chromodomain Inhibitors高亲和力CHD1染色质结构域抑制剂的研发
errJournal of Medicinal Chemistry
IF6.8
err2026-05-05
err0
errOAAI
errHolger Greschik; Florian Friedrich; Ludwig Seifert; Farnoush Mousavizadeh; Francesco Fiorentino; Johannes Walz; Lin Zhang; Jianyu Li; Emanuele Fabbrizi; Stefano Tomassi; Farhad Panahi; Niklas Papenkordt; Silas L. Wurnig; Johannes Osterroth; Anna M. Strasser; Jan Ruprecht; Aurélien F. A. Moumbock; Martin Hügle; Manuela Sum; Ling Peng; Sheng Wang; Adina A. Baniahmad; Laura Pulido-Cortés; H. Th. Marc Timmers; Ralf Flaig; Eric Metzger; Bernhard Breit; Oliver Einsle; Stefan Günther; Dante Rotili; Antonello Mai; Roland Schüle; Manfred Jung
err分享
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Correction of the molecular phenotype of X-linked Dystonia-Parkinsonism reveals a non-canonical function of BRD4X-连锁肌张力障碍-帕金森病的分子表型纠正揭示了BRD4的非经典功能
errNature Communications
IF15.7
err2026-05-05
err0
errOAAI
errSimona Capponi; Sandra Ehret; Zeynep Camgöz; Fabian Gather; Christine A. Vaine; Ezgi Özyerli-Göknar; Marie Follo; D. Cristopher Bragg; Tanja Vogel; H. Th. Marc Timmers
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Menin-inhibition enhances graft-versus-leukemia effects by T-cell activation and endogenous retrovirus induction in AMLMenin抑制通过T细胞活化及内源性逆转录病毒诱导增强移植物抗白血病效应（AML）
errBlood
IF23.1
err2025-10-30
err0
PREAI
errViktor Fetsch; Lennard Schwöbel; Ezgi Ozyerli-Goknar; Anna-Verena Stell; Marco Punta; Thomas Plenge; Tabea Klaus; Manoj K. Gupta; Geoffroy Andrieux; Khalid Shoumariyeh; Sophie Pfeiffer; Eyleen Corrales; Lina Schlenke; Hosna Baniadam; Simon M. Brandl; Massimo Andreis; Michal Remen; Alina Hartmann; Kathleen Grueter; Melissa Zwick; Natalie Köhler; Monika Kuban; Eric Metzger; Christoph Rummelt; Justus Duyster; Melanie Boerries; Maike Hofmann; Julian Färber; Lukas Braun; Alexander J. Zähringer; Michael Lübbert; Cristina Toffalori; Luca Vago; Florian H. Heidel; Susana Minguet; Petya Apostolova; Tobias Feuchtinger; Kristina Maas-Bauer; Franziska Blaeschke; Michael W.M. Kühn; H.Th.Marc Timmers; Tobias Wertheimer; Florian Perner; Robert Zeiser
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Molecular determinants for recognition of serotonylated chromatin血清素化染色质的识别分子决定因素
errNUCLEIC ACIDS RESEARCH
IF13.1
err2025-07-22
err0
errOAAI
errPulido-Cortes, Laura; Gielingh, Hajo; Thijssen, Vito; Liu, Minglong; Yoshisada, Ryoji; Soares, Leonardo Romao; Nizamuddin, Sheikh; Friedrich, Florian; Greschik, Holger; Peng, Ling; Honorato, Rodrigo Vargas; Jung, Manfred; Bonvin, Alexandre M. J. J.; Biniossek, Martin L.; Schuele, Roland; Jongkees, Seino; van Ingen, Hugo; Timmers, H. Th Marc
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Herpesviruses mimic zygotic genome activation to promote viral replication (vol 16, 710, 2025)疱疹病毒模拟合子基因组激活以促进病毒复制（vol 16, 710, 2025）
errNATURE COMMUNICATIONS
IF15.7
err2025-03-05
err0
errOAAI
errNeugebauer, Eva; Walter, Stephanie; Tan, Jiang; Drayman, Nir; Franke, Vedran; van Gent, Michiel; Pennisi, Sandra; Veratti, Pia; Stein, Karla S.; Welker, Isabelle; Tay, Savas; Verjans, Georges M. G. M.; Timmers, H. T. Marc; Akalin, Altuna; Landthaler, Markus; Ensser, Armin; Wyler, Emanuel
err分享
err收藏
KDM5C and KDM5D mutations have different consequences in clear cell renal cell carcinoma cells
errCOMMUNICATIONS BIOLOGY
IF5.1
err2025-02-15
err0
errOAAI
errMueller, Marvin; Zodel, Kyra; Abhari, Behnaz A.; Cuomo, Francesca; Nizamuddin, Sheikh; Metzger, Patrick; Boerries, Melanie; Timmers, H. T. Marc; Frew, Ian J.
err分享
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SMARCCI Controls the Oncogenic NOTCH1 Transcriptional Program in T-Cell Acute Lymphoblastic LeukemiaSMARCCI调控T细胞急性淋巴细胞白血病中致癌性NOTCH1转录程序
errBLOOD
IF23.1
err2024-11-05
err0
PREAI
errShoumariyeh, Khalid; Sun, Xiaoyang; Poggio, Teresa; Andrieux, Geoffroy; Schmitz, Tatjan; de Bra, Stephan; Fotouhi, Omid; Nizamuddin, Sheikh; Martens, Uta Sabine Sabine; Duyster, Justus; Timmers, Marc; Boerries, Melanie; Miething, Cornelius
err分享
err收藏
Epigenetic modulation via the C-terminal tail of H2A.Z
errNATURE COMMUNICATIONS
IF15.7
err2024-10-24
err0
errOAAI
errImre, Laszlo; Nanasi, Peter; Benhamza, Ibtissem; Enyedi, Kata Nora; Mocsar, Gabor; Bosire, Rosevalentine; Hegedus, Eva; Niaki, Erfaneh Firouzi; Csoti, Agota; Darula, Zsuzsanna; Csosz, Eva; Poliska, Szilard; Scholtz, Beata; Mezo, Gabor; Bacso, Zsolt; Timmers, H. T. Marc; Kusakabe, Masayuki; Balazs, Margit; Vamosi, Gyorgy; Ausio, Juan; Cheung, Peter; Toth, Katalin; Tremethick, David; Harata, Masahiko; Szabo, Gabor
err分享
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Oncogenic enhancers prime quiescent metastatic cells to escape NK immune surveillance by eliciting transcriptional memory致癌增强子通过引发转录记忆来激发静止的转移细胞以逃避NK免疫监视
errNATURE COMMUNICATIONS
IF15.7
err2024-03-19
err0
errOAAI
errMichelatti, Daniela; Beyes, Sven; Bernardis, Chiara; Negri, Maria Luce; Morelli, Leonardo; Bediaga, Naiara Garcia; Poli, Vittoria; Fagnocchi, Luca; Lago, Sara; D'Annunzio, Sarah; Cona, Nicole; Gaspardo, Ilaria; Bianchi, Aurora; Jovetic, Jovana; Gianesello, Matteo; Turdo, Alice; D'Accardo, Caterina; Gaggianesi, Miriam; Dori, Martina; Forcato, Mattia; Crispatzu, Giuliano; Rada-Iglesias, Alvaro; Sosa, Maria Soledad; Timmers, H. T. Marc; Bicciato, Silvio; Todaro, Matilde; Tiberi, Luca; Zippo, Alessio
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Epigenetic-focused CRISPR/Cas9 screen identifies (absent, small, or homeotic)2-like protein (ASH2L) as a regulator of glioblastoma cell survival
errCELL COMMUNICATION AND SIGNALING
IF8.9
err2023-11-16
err5
errOAAI
errOzyerli-Goknar, Ezgi; Kala, Ezgi Yagmur; Aksu, Ali Cenk; Bulut, Ipek; Cingoz, Ahmet; Nizamuddin, Sheikh; Biniossek, Martin; Seker-Polat, Fidan; Morova, Tunc; Aztekin, Can; Kung, Sonia H. Y.; Syed, Hamzah; Tuncbag, Nurcan; Gonen, Mehmet; Philpott, Martin; Cribbs, Adam P.; Acilan, Ceyda; Lack, Nathan A.; Onder, Tamer T.; Timmers, H. T. Marc; Bagci-Onder, Tugba
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ATAC and SAGA co-activator complexes utilize co-translational assembly, but their cellular localization properties and functions are distinctATAC和SAGA共激活复合物利用共翻译组装，但它们的细胞定位特性和功能不同
errCELL REPORTS
IF6.9
err2023-09-01
err3
errOAAI
errYayli, Gizem; Bernardini, Andrea; Sanchez, Paulina Karen Mendoza; Scheer, Elisabeth; Damilot, Mylene; Essabri, Karim; Morlet, Bastien; Negroni, Luc; Vincent, Stephane D.; Timmers, H. T. Marc; Tora, Laszlo
err分享
err收藏
Hierarchical TAF1-dependent co-translational assembly of the basal transcription factor TFIID
errNATURE STRUCTURAL & MOLECULAR BIOLOGY
IF10.1
err2023-06-29
err9
errOAAI
errBernardini, Andrea; Mukherjee, Pooja; Scheer, Elisabeth; Kamenova, Ivanka; Antonova, Simona; Mendoza Sanchez, Paulina Karen; Yayli, Gizem; Morlet, Bastien; Timmers, H. T. Marc; Tora, Laszlo
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err收藏
NC2α interacts with BTAF1 and stimulates its ATP-dependent association with TATA-binding protein
errMOLECULAR AND CELLULAR BIOLOGY
IF2.7
err2023-03-27
err33
errOAAI
errKlejman, MP; Pereira, LA; van Zeeburg, HJT; Gilfillan, S; Meisterernst, M; Timmers, HTM
err分享
err收藏
Differential requirement of SAGA subunits for Mot1p and Taf1p recruitment in gene activation
errMOLECULAR AND CELLULAR BIOLOGY
IF2.7
err2023-03-27
err23
errOAAI
errvan Oevelen, CJC; van Teeffelen, HAAM; Timmers, HTM
err分享
err收藏
TAFII170 interacts with the concave surface of TATA-Binding protein to inhibit its DNA binding activity
errMOLECULAR AND CELLULAR BIOLOGY
IF2.7
err2023-03-27
err33
errOAAI
errPereira, LA; van der Knaap, JA; van den Boom, V; van den Heuvel, FAJ; Timmers, HTM
err分享
err收藏
The Multiple Endocrine Neoplasia Type 1 (MEN1) Tumor Suppressor Regulates Peroxisome Proliferator-Activated Receptor γ-Dependent Adipocyte Differentiation
errMOLECULAR AND CELLULAR BIOLOGY
IF2.7
err2023-03-21
err57
errOAAI
errDreijerink, Koen M. A.; Varier, Radhika A.; van Beekum, Olivier; Jeninga, Ellen H.; Hoeppener, Jo W. M.; Lips, Cornelis J. M.; Kummer, J. Alain; Kalkhoven, Eric; Timmers, H. T. Marc
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PHF8 Targets Histone Methylation and RNA Polymerase II To Activate Transcription
errMOLECULAR AND CELLULAR BIOLOGY
IF2.7
err2023-03-20
err102
errOAAI
errFortschegger, Klaus; de Graaf, Petra; Outchkourov, Nikolay S.; van Schaik, Frederik M. A.; Timmers, H. T. Marc; Shiekhattar, Ramin
err分享
err收藏
Quantitative Dissection and Stoichiometry Determination of the Human SET1/MLL Histone Methyltransferase Complexes
errMOLECULAR AND CELLULAR BIOLOGY
IF2.7
err2023-03-20
err185
errOAAI
errvan Nuland, Rick; Smits, Arne H.; Pallaki, Paschalina; Jansen, Pascal W. T. C.; Vermeulen, Michiel; Timmers, H. T. Marc
err分享
err收藏
Evolutionary conservation of the fidelity of transcription
errNATURE COMMUNICATIONS
IF15.7
err2023-03-20
err12
errOAAI
errChung, Claire; Verheijen, Bert M.; Navapanich, Zoe; McGann, Eric G.; Shemtov, Sarah; Lai, Guan-Ju; Arora, Payal; Towheed, Atif; Haroon, Suraiya; Holczbauer, Agnes; Chang, Sharon; Manojlovic, Zarko; Simpson, Stephen; Thomas, Kelley W.; Kaplan, Craig; van Hasselt, Peter; Timmers, Marc; Erie, Dorothy; Chen, Lin; Gout, Jean-Francois; Vermulst, Marc
err分享
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研究方向

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