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Viktor Brabec

palacky university

67H指数
588论文数
1.7W被引数
收录论文 167
发表时间
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Novel 2-(2′-Benzothiazolyl)-benzimidazole-Based Iridium(III) Photocatalysts Exhibit Antiproliferative Effects in 2D and 3D Cancer Cells to Bypass Hypoxia-Induced Resistance新型2-(2′-苯并噻唑基)-苯并咪唑基铱(III)光催化剂在二维和三维癌细胞中表现出抗增殖作用以绕过缺氧诱导的耐药性
errJournal of Medicinal Chemistry
IF6.8
err2026-03-16
err0
errOAAI
errAntonio Linero-Artiaga; Marie Svitelova; Vojtěch Novohradský; Venancio Rodríguez; Lenka Markova; Jana Kasparkova; Christoph Janiak; José Ruiz; Viktor Brabec
err分享
err收藏
Photocatalytic arylterpyridine iridium(III) complexes trigger oncosis in 2D and 3D cancer cell models via NADH oxidation光催化芳基三吡啶铱(III)配合物通过NADH氧化在二维和三维癌细胞模型中触发凋亡小体形成
errInorg. Chem. Front.
IF0
err2025-12-24
err0
errOAAI
errIsabel José Romero-Castellón; Lenka Markova; María José Piernas-Muñoz; Hana Kostrhunova; Jana Kasparkova; Christoph Janiak; Marta Erminia Alberto; Antonio Francés-Monerris; Jose Ruiz; Viktor Brabec
err分享
err收藏
Platinum(IV) oxaliplatin analog containing axial benzoate ligands induces mitochondrial hyperpolarization and caspase-dependent apoptosis in pancreatic cancer cell models含轴向苯甲酸配体的铂(IV)奥沙利铂类似物诱导胰腺癌细胞模型中线粒体超极化和半胱天冬酶依赖性凋亡
errChemico-Biological Interactions
IF5.4
err2025-11-03
err0
PREAI
errMichal Berecka; Jitka Pracharova; Nicola Margiotta; Alessandra Barbanente; Nicoletta Ditaranto; Jana Kasparkova; Viktor Brabec
err分享
err收藏
Crizotinib- or Ceritinib-Conjugated Platinum(IV) Prodrugs As Potent Multiaction Agents Inducing Antiproliferative Effects in 2D and 3D Cancer Cell Models克唑替尼或塞瑞替尼偶联的铂(IV)前药作为诱导2D和3D癌细胞模型抗增殖效应的强效多作用剂
errJOURNAL OF MEDICINAL CHEMISTRY
IF6.8
err2025-11-01
err0
PREAI
errSharkawy, Sofia; Acharya, Sourav; Kostrhunova, Hana; Maji, Moumita; Markova, Lenka; Novohradsky, Vojtech; Gibson, Dan; Brabec, Viktor
err分享
err收藏
A novel benzothiazole-1,2,3-triazole-based arene osmium(ii) complex as an effective rhabdomyosarcoma cancer stem cell agent
errINORGANIC CHEMISTRY FRONTIERS
IF6.4
err2025-01-01
err0
errOAAI
errSharkawy, Sofia; Hernandez-Garcia, Alba; Kostrhunova, Hana; Bautista, Delia; Markova, Lenka; Santana, Maria Dolores; Kasparkova, Jana; Brabec, Viktor; Ruiz, Jose
err分享
err收藏
A Novel Substituted Benzo[g]quinoxaline-Based Cyclometalated Ru(II) Complex as a Biocompatible Membrane-Targeted PDT Colon Cancer Stem Cell Agent
errJOURNAL OF MEDICINAL CHEMISTRY
IF6.8
err2024-12-02
err0
errOAAI
errMarco, Alicia; Kasparkova, Jana; Bautista, Delia; Kostrhunova, Hana; Cutillas, Natalia; Markova, Lenka; Novohradsky, Vojtech; Ruiz, Jose; Brabec, Viktor
err分享
err收藏
Ni(II) Cylinders Damage DNA in Cancer Cells and Preferentially Bind Y-Shaped DNA Three-Way Junctions Blocking DNA SynthesisNi(II) 圆柱体破坏癌细胞中的DNA并优先结合Y形DNA三向连接阻止DNA合成
errSMALL
IF12.1
err2024-10-20
err0
errOAAI
errMalina, Jaroslav; Kostrhunova, Hana; Brabec, Viktor
err分享
err收藏
Multiaction Pt(IV) Prodrugs Releasing Cisplatin and Dasatinib Are Potent Anticancer and Anti-Invasive Agents Displaying Synergism between the Two Drugs
errJOURNAL OF MEDICINAL CHEMISTRY
IF6.8
err2024-05-31
err0
PREAI
errMarkova, Lenka; Maji, Moumita; Kostrhunova, Hana; Novohradsky, Vojtech; Kasparkova, Jana; Gibson, Dan; Brabec, Viktor
err分享
err收藏
Dicobalt(II) helices kill colon cancer cells via enantiomer-specific mechanisms; DNA damage or microtubule disruptionDicobalt(II) 螺旋通过对映体特异性机制杀死结肠癌细胞; DNA损伤或微管破坏
errCHEMICAL SCIENCE
IF7.4
err2024-01-01
err0
errOAAI
errSong, Hualong; Kostrhunova, Hana; Cervinka, Jakub; Macpherson, Julie; Malina, Jaroslav; Rajan, Teena; Phillips, Roger; Postings, Miles; Shepherd, Samantha; Zhang, Xuejian; Brabec, Viktor; Rogers, Nicola J.; Scott, Peter
err分享
err收藏
New cyclometalated Ru(II) polypyridyl photosensitizers trigger oncosis in cancer cells by inducing damage to cellular membranes新的环金属化Ru(II) 多吡啶光敏剂通过诱导细胞膜损伤引发癌细胞的肿瘤
errINORGANIC CHEMISTRY FRONTIERS
IF6.4
err2024-01-01
err4
errOAAI
errCervinka, Jakub; Hernandez-Garcia, Alba; Bautista, Delia; Markova, Lenka; Kostrhunova, Hana; Malina, Jaroslav; Kasparkova, Jana; Santana, M. Dolores; Brabec, Viktor; Ruiz, Jose
err分享
err收藏
Novel 2-(5-Arylthiophen-2-yl)-benzoazole Cyclometalated Iridium(III) dppz Complexes Exhibit Selective Phototoxicity in Cancer Cells by Lysosomal Damage and Oncosis
errJOURNAL OF MEDICINAL CHEMISTRY
IF6.8
err2023-12-23
err12
errOAAI
errKasparkova, Jana; Hernandez-Garcia, Alba; Kostrhunova, Hana; Goicuria, Marta; Novohradsky, Vojtech; Bautista, Delia; Markova, Lenka; Santana, Maria Dolores; Brabec, Viktor; Ruiz, Jose
err分享
err收藏
Multitargeting Prodrugs that Release Oxaliplatin, Doxorubicin and Gemcitabine are Potent Inhibitors of Tumor Growth and Effective Inducers of Immunogenic Cell Death
errANGEWANDTE CHEMIE-INTERNATIONAL EDITION
IF16.9
err2023-09-12
err14
errOAAI
errSarkar, Amrita; Novohradsky, Vojtech; Maji, Moumita; Babu, Tomer; Markova, Lenka; Kostrhunova, Hana; Kasparkova, Jana; Gandin, Valentina; Brabec, Viktor; Gibson, Dan
err分享
err收藏
Ir(III) Compounds Containing a Terdentate Ligand Are Potent Inhibitors of Proliferation and Effective Antimetastatic Agents in Aggressive Triple-Negative Breast Cancer Cells
errJOURNAL OF MEDICINAL CHEMISTRY
IF6.8
err2023-07-06
err8
errOAAI
errNovohradsky, Vojtech; Marco, Alicia; Markova, Lenka; Cutillas, Natalia; Ruiz, Jose; Brabec, Viktor
err分享
err收藏
Palladium and Platinum Complexes of the Antimetabolite Fludarabine with Vastly Enhanced Selectivity for Tumour over Non-Malignant Cells
errMOLECULES
IF4.6
err2023-07-02
err5
errOAAI
errSchleser, Sebastian W. W.; Krytovych, Oleksandr; Ziegelmeier, Tim; Gross, Elisabeth; Kasparkova, Jana; Brabec, Viktor; Weber, Thomas; Schobert, Rainer; Mueller, Thomas
err分享
err收藏
Metallohelices stabilize DNA three-way junctions and induce DNA damage in cancer cells
errNUCLEIC ACIDS RESEARCH
IF13.1
err2023-06-23
err5
errOAAI
errMalina, Jaroslav; Kostrhunova, Hana; Scott, Peter; Brabec, Viktor
err分享
err收藏
Platinum(IV) Derivatives of [Pt(1S,2S-diaminocyclohexane)(5,6-dimethyl-1,10-phenanthroline)] with Diclofenac Ligands in the Axial Positions: A New Class of Potent Multi-action Agents Exhibiting Selectivity to Cancer Cells
errJOURNAL OF MEDICINAL CHEMISTRY
IF6.8
err2023-06-07
err13
errOAAI
errKostrhunova, Hana; McGhie, Brondwyn S.; Markova, Lenka; Novakova, Olga; Kasparkova, Jana; Aldrich-Wright, Janice R.; Brabec, Viktor
err分享
err收藏
Cyclometalated Benzimidazole Osmium(II) Complexes with Antiproliferative Activity in Cancer Cells Disrupt Calcium Homeostasis
errINORGANIC CHEMISTRY
IF4.7
err2023-04-11
err7
errOAAI
errHernandez-Garcia, Alba; Markova, Lenka; Santana, Maria Dolores; Pracharova, Jitka; Bautista, Delia; Kostrhunova, Hana; Novohradsky, Vojtech; Brabec, Viktor; Ruiz, Jose; Kasparkova, Jana
err分享
err收藏
Asymmetric triplex metallohelices stabilise DNA G-quadruplexes in promoter oncogene sequences and efficiently reduce their expression in cancer cells
errJOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY
IF5.4
err2023-04-05
err2
errOAAI
errMalina, Jaroslav; Kostrhunova, Hana; Song, Hualong; Scott, Peter; Brabec, Viktor
err分享
err收藏
Ruthenium(II)-Tris-pyrazolylmethane Complexes Inhibit Cancer Cell Growth by Disrupting Mitochondrial Calcium Homeostasis
errJOURNAL OF MEDICINAL CHEMISTRY
IF6.8
err2022-08-01
err31
errOAAI
errCervinka, Jakub; Gobbo, Alberto; Biancalana, Lorenzo; Markova, Lenka; Novohradsky, Vojtech; Guelfi, Massimo; Zacchini, Stefano; Kasparkova, Jana; Brabec, Viktor; Marchetti, Fabio
err分享
err收藏
Metallohelix vectors for efficient gene delivery via cationic DNA nanoparticles用于通过阳离子DNA纳米颗粒进行有效基因传递的金属螺旋载体
errNUCLEIC ACIDS RESEARCH
IF13.1
err2022-01-08
err11
errOAAI
errMalina, Jaroslav; Kostrhunova, Hana; Novohradsky, Vojtech; Scott, Peter; Brabec, Viktor
err分享
err收藏

研究方向

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合作期刊
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Peter J. Sadler
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H 指数: 120 · 论文数: 1.6K
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Lawrence S. Young
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Christoph Janiak
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