Gyanendra Kumar - Publications, H-index & Citations

Gyanendra Kumar

united states department of energy (doe)

28H指数

101论文数

2.0K被引数

收录论文 28

发表时间

A secure and trustworthy blockchain-assisted edge computing architecture for industrial internet of things 一种安全可信的区块链辅助边缘计算架构，用于工业物联网

SCIENTIFIC REPORTS

IF3.9

2025-05-02

OAAI

Asaithambi, Sasikumar; Nallusamy, Senthilkumar; Yang, Jing; Prajapat, Sunil; Kumar, Gyanendra; Rathore, Pramod Singh

Chemical scaffold recycling: Structure-guided conversion of an HIV integrase inhibitor into a potent influenza virus RNA-dependent RNA polymerase inhibitor designed to minimize resistance potential

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

IF5.9

2023-02-01

OAAI

Slavish, Peter J.; Cuypers, Maxime G.; Rimmer, Mary Ashley; Abdolvahabi, Alireza; Jeevan, Trushar; Kumar, Gyanendra; Jarusiewicz, Jamie A.; Vaithiyalingam, Sivaraja; Jones, Jeremy C.; Bowling, John J.; Price, Jeanine E.; DuBois, Rebecca M.; Min, Jaeki; Webby, Richard J.; Rankovic, Zoran; White, Stephen W.

Structural insights into the substrate specificity of the endonuclease activity of the influenza virus cap-snatching mechanism

NUCLEIC ACIDS RESEARCH

IF13.1

2021-01-19

OAAI

Kumar, Gyanendra; Cuypers, Maxime; Webby, Richard R.; Webb, Thomas R.; White, Stephen W.

Structure-Activity Relationship Study of Novel 6-Aryl-2-benzoyl-pyridines as Tubulin Polymerization Inhibitors with Potent Antiproliferative Properties

JOURNAL OF MEDICINAL CHEMISTRY

IF6.8

2019-12-20

PREAI

Chen, Hao; Deng, Shanshan; Wang, Yuxi; Albadari, Najah; Kumar, Gyanendra; Ma, Dejian; Li, Weimin; White, Stephen W.; Miller, Duane D.; Li, Wei

Colchicine Binding Site Agent DJ95 Overcomes Drug Resistance and Exhibits Antitumor Efficacy

MOLECULAR PHARMACOLOGY

IF3

2019-07-01

OAAI

Arnst, Kinsie E.; Wang, Yuxi; Lei, Zi-Ning; Hwang, Dong-Jin; Kumar, Gyanendra; Ma, Dejian; Parke, Deanna N.; Chen, Qiang; Yang, Jinliang; White, Stephen W.; Seagroves, Tiffany N.; Chen, Zhe-Sheng; Miller, Duane D.; Li, Wei

Structure-Guided Design, Synthesis, and Biological Evaluation of (2-(1H-Indo1-3-yl)-1H-imidazol-4-yl)(3,4,5-trinnethoxyphenyl) Methanone (ABI-231) Analogues Targeting the Colchicine Binding Site in Tubulin

JOURNAL OF MEDICINAL CHEMISTRY

IF6.8

2019-06-28

PREAI

Wang, Qinghui; Arnst, Kinsie E.; Wang, Yuxi; Kumar, Gyanendra; Ma, Dejian; White, Stephen W.; Miller, Duane D.; Li, Weimin; Li, Wei

Identification of the I38T PA Substitution as a Resistance Marker for Next-Generation Influenza Virus Endonuclease Inhibitors (vol 9, e00a30-18, 2018)

MBIO

IF4.7

2018-12-21

OAAI

Jones, Jeremy C.; Kumar, Gyanendra; Barman, Subrata; Najera, Isabel; White, Stephen W.; Webby, Richard J.; Govorkova, Elena A.

Structural Modification of the 3,4,5-Trimethoxyphenyl Moiety in the Tubulin Inhibitor VERU-111 Leads to Improved Antiproliferative Activities

JOURNAL OF MEDICINAL CHEMISTRY

IF6.8

2018-08-20

OAAI

Wang, Qinghui; Arnst, Kinsie E.; Wang, Yuxi; Kumar, Gyanendra; Ma, Dejian; Chen, Hao; Wu, Zhongzhi; Yang, Jinliang; White, Stephen W.; Miller, Duane D.; Li, Wei

The Structural and Functional Basis for Recurring Sulfa Drug Resistance Mutations in Staphylococcus aureus Dihydropteroate Synthase

FRONTIERS IN MICROBIOLOGY

IF4.5

2018-07-17

OAAI

Griffith, Elizabeth C.; Wallace, Miranda J.; Wu, Yinan; Kumar, Gyanendra; Gajewski, Stefan; Jackson, Pamela; Phelps, Gregory A.; Zheng, Zhong; Rock, Charles O.; Lee, Richard E.; White, Stephen W.

Identification of the I38T PA Substitution as a Resistance Marker for Next-Generation Influenza Virus Endonuclease Inhibitors

MBIO

IF4.7

2018-05-02

OAAI

Jones, Jeremy C.; Kumar, Gyanendra; Barman, Subrata; Najera, Isabel; White, Stephen W.; Webby, Richard J.; Govorkova, Elena A.

Heterocyclic-Fused Pyrimidines as Novel Tubulin Polymerization Inhibitors Targeting the Colchicine Binding Site: Structural Basis and Antitumor Efficacy

JOURNAL OF MEDICINAL CHEMISTRY

IF6.8

2018-02-12

OAAI

Banerjee, Souvik; Arnst, Kinsie E.; Wang, Yuxi; Kumar, Gyanendra; Deng, Shanshan; Yang, Lei; Li, Guo-bo; Yang, Jinbang; White, Stephen W.; Li, Wei; Miller, Duane D.

Protein-Structure Assisted Optimization of 4,5-Dihydroxypyrimidine-6-Carboxamide Inhibitors of Influenza Virus Endonuclease

SCIENTIFIC REPORTS

IF3.9

2017-12-07

OAAI

Beylkin, Diane; Kumar, Gyanendra; Zhou, Wei; Park, Jaehyeon; Jeevan, Trushar; Lagisetti, Chandraiah; Harfoot, Rhodri; Webby, Richard J.; White, Stephen W.; Webb, Thomas R.

A two-helix motif positions the lysophosphatidic acid acyltransferase active site for catalysis within the membrane bilayer

NATURE STRUCTURAL & MOLECULAR BIOLOGY

IF10.1

2017-07-17

OAAI

Robertson, Rosanna M.; Yao, Jiangwei; Gajewski, Stefan; Kumar, Gyanendra; Martin, Erik W.; Rock, Charles O.; White, Stephen W.

An Amino Acid in the Stalk Domain of N1 Neuraminidase Is Critical for Enzymatic Activity

JOURNAL OF VIROLOGY

IF3.8

2017-01-15

OAAI

Zanin, Mark; Duan, Susu; Wong, Sook-San; Kumar, Gyanendra; Baviskar, Pradyumna; Collin, Emily; Russell, Charles; Barman, Subrata; Hause, Benjamin; Webby, Richard

Small molecule non-peptide inhibitors of botulinum neurotoxin serotype E: Structure-activity relationship and a pharmacophore model

BIOORGANIC & MEDICINAL CHEMISTRY

IF3

2016-09-01

OAAI

Kumar, Gyanendra; Agarwal, Rakhi; Swaminathan, Subramanyam

N-acylhydrazone inhibitors of influenza virus PA endonuclease with versatile metal binding modes

SCIENTIFIC REPORTS

IF3.9

2016-08-11

OAAI

Carcelli, Mauro; Rogolino, Dominga; Gatti, Anna; De Luca, Laura; Sechi, Mario; Kumar, Gyanendra; White, Stephen W.; Stevaert, Annelies; Naesens, Lieve

Identification and characterization of influenza variants resistant to a viral endonuclease inhibitor

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2016-03-14

OAAI

Song, Min-Suk; Kumar, Gyanendra; Shadrick, William R.; Zhou, Wei; Jeevan, Trushar; Li, Zhenmei; Slavish, P. Jake; Fabrizio, Thomas P.; Yoon, Sun-Woo; Webb, Thomas R.; Webby, Richard J.; White, Stephen W.

Unique Determinants of Neuraminidase Inhibitor Resistance among N3, N7, and N9 Avian Influenza Viruses

JOURNAL OF VIROLOGY

IF3.8

2015-11-01

OAAI

Song, Min-Suk; Marathe, Bindumadhav M.; Kumar, Gyanendra; Wong, Sook-San; Rubrum, Adam; Zanin, Mark; Choi, Young-Ki; Webster, Robert G.; Govorkova, Elena A.; Webby, Richard J.

The identification, analysis and structure-based development of novel inhibitors of 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase

BIOORGANIC & MEDICINAL CHEMISTRY

IF3

2014-04-01

OAAI

Yun, Mi-Kyung; Hoagland, Daniel; Kumar, Gyanendra; Waddell, M. Brett; Rock, Charles O.; Lee, Richard E.; White, Stephen W.

Discovery of a fluorene class of compounds as inhibitors of botulinum neurotoxin serotype E by virtual screening

CHEMICAL COMMUNICATIONS

IF4.2

2012-01-01

PREAI

Kumar, Gyanendra; Agarwal, Rakhi; Swaminathan, Subramanyam

研究方向