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Frédéric G. Buono

Boehringer Ingelheim Pharmaceuticals

21H指数
91论文数
1.4K被引数
收录论文 49
发表时间
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Nickel/Photoredox-Catalyzed Enantioselective α-Aminoalkylation of 2-Iodopyridines镍/光氧化还原催化催化的2-碘吡啶的不对称α-氨基烷基化
errACS Catalysis
IF13.1
err2026-03-13
err0
PREAI
errZhen Lei; H. Ray Kelly; Jason An; Suttipol Radomkit; Xiaole Shao; Saad Khattabi; David Cabanero; Qi Jiang; Clodette Punzalan; Rittik K. Ghosh; Maitreyee Rawat; Frederic G. Buono
err分享
err收藏
Collective intelligence for AI-assisted chemical synthesis人工智能辅助化学合成的集体智能
errNature
IF48.5
err2026-01-19
err0
PREAI
errHaote Li; Sumon Sarkar; Wenxin Lu; Patrick O. Loftus; Tianyin Qiu; Yu Shee; Abbigayle E. Cuomo; John-Paul Webster; H. Ray Kelly; Vidhyadhar Manee; Sanil Sreekumar; Frederic G. Buono; Robert H. Crabtree; Timothy R. Newhouse; Victor S. Batista
err分享
err收藏
Leveraging an intelligent slug flow platform for self-optimization of reaction systems with categorical variables利用智能 slug 流平台对含分类变量的反应系统进行自优化
errChem. Sci.
IF7.4
err2025-10-13
err0
errOAAI
errFlorian Wagner; Gernot Neun; Thomas Tampone; Zhen Lei; Frederic Buono; Christopher A. Hone; C. Oliver Kappe
err分享
err收藏
Enabling the First Scale-Up of the Selective HER2 Inhibitor BI-4142实现选择性HER2抑制剂BI-4142的首个规模化生产
errORGANIC PROCESS RESEARCH & DEVELOPMENT
IF3.5
err2025-05-14
err0
PREAI
errChong, Eugene; Li, Ruoshi; Dong, Weitong; Chevliakov, Maxim; Tampone, Thomas G.; Zhang, Yongda; Qu, Bo; Haddad, Nizar; Lorenz, Jon C.; Sarvestani, Max; Omar, Thuraya; Li, Huayu; Gao, Joe J.; Gao, Donghong A.; Pennino, Scott; Wu, Ling; Spinelli, Earl; Yao, Steven; Lee, Heewon; Buono, Frederic; Song, Jinhua J.; Wilding, Birgit
err分享
err收藏
Biocatalytic Reduction of Heterocyclic Imines in Continuous Flow with Immobilized Enzymes固定化酶在连续流中对杂环亚胺的生物催化还原
errACS SUSTAINABLE CHEMISTRY & ENGINEERING
IF7.3
err2025-03-24
err0
PREAI
errBenítez-Mateos, AI; Lim, D; Padrosa, DR; Marchini, V; Wu, H; Buono, F; Paradisi, F
err分享
err收藏
Synthesis of a spiroketone intermediate featuring a green and sustainable telescoped flow process
errREACTION CHEMISTRY & ENGINEERING
IF3.1
err2025-03-01
err0
PREAI
errWang, Shuoxun; Wu, Hao; Zhang, Yongda; Buono, Frederic
err分享
err收藏
Oxoammonium-Catalyzed Oxidation of N-Substituted AminesN-取代胺的氧代铵催化氧化
errJOURNAL OF THE AMERICAN CHEMICAL SOCIETY
IF15.6
err2024-11-11
err1
PREAI
errRein, Jonas; Gorski, Bartosz; Cheng, Yukun; Lei, Zhen; Buono, Frederic; Lin, Song
err分享
err收藏
Site-specific template generative approach for retrosynthetic planning用于逆向综合计划的特定于站点的模板生成方法
errNATURE COMMUNICATIONS
IF15.7
err2024-09-06
err0
errOAAI
errShee, Yu; Li, Haote; Zhang, Pengpeng; Nikolic, Andrea M.; Lu, Wenxin; Kelly, H. Ray; Manee, Vidhyadhar; Sreekumar, Sanil; Buono, Frederic G.; Song, Jinhua J.; Newhouse, Timothy R.; Batista, Victor S.
err分享
err收藏
G-EnzyBeads for Biocatalysis Screening Facilitated by Volumetric Dosing
errORGANIC PROCESS RESEARCH & DEVELOPMENT
IF3.5
err2024-08-02
err0
PREAI
errFejzagic, Alexander V.; Schmid, Matthias; Kollmus, Philipp; Wu, Hao; Buono, Frederic; Santagostino, Marco
err分享
err收藏
Self-Optimizing Flow Reactions for Sustainability: An Experimental Bayesian Optimization Study
errACS SUSTAINABLE CHEMISTRY & ENGINEERING
IF7.3
err2024-06-19
err0
errOAAI
errWagner, Florian L.; Sagmeister, Peter; Tampone, Thomas G.; Manee, Vidhyadhar; Yerkozhanov, Dauzhan; Buono, Frederic G.; Williams, Jason D.; Kappe, C. Oliver
err分享
err收藏
Ligand-Based Principal Component Analysis Followed by Ridge Regression: Application to an Asymmetric Negishi Reaction
errACS CATALYSIS
IF13.1
err2024-03-20
err2
PREAI
errKelly, H. Ray; Sreekumar, Sanil; Manee, Vidhyadhar; Cuomo, Abbigayle E.; Newhouse, Timothy R.; Batista, Victor S.; Buono, Frederic
err分享
err收藏
Photochemistry in Pharmaceutical Development: A Survey of Strategies and Approaches to Industry-wide Implementation药物开发中的光化学: 全行业实施策略和方法的调查
errORGANIC PROCESS RESEARCH & DEVELOPMENT
IF3.5
err2024-03-08
err12
PREAI
errMoschetta, Eric G.; Cook, Gemma C.; Edwards, Lee J.; Ischay, Michael A.; Lei, Zhen; Buono, Frederic; Levesque, Francois; Garber, Jeffrey A. O.; MacTaggart, Maura; Sezen-Edmonds, Melda; Cole, Kevin P.; Beaver, Matthew G.; Doerfler, Jaika; Opalka, Suzanne M.; Liang, Wenli; Morse, Peter D.; Miyake, Naomi
err分享
err收藏
A Slug Flow Platform with Multiple Process Analytics Facilitates Flexible Reaction Optimization
errADVANCED SCIENCE
IF14.1
err2024-01-25
err8
errOAAI
errWagner, Florian; Sagmeister, Peter; Jusner, Clemens E.; Tampone, Thomas G.; Manee, Vidhyadhar; Buono, Frederic G.; Williams, Jason D.; Kappe, C. Oliver
err分享
err收藏
Development of a Scalable Synthesis toward a KRAS G12C Inhibitor Building Block Bearing an All-Carbon Quaternary Stereocenter, Part 2: Asymmetric Synthesis via Shi Epoxidation
errORGANIC PROCESS RESEARCH & DEVELOPMENT
IF3.5
err2024-01-05
err4
PREAI
errTan, Zhulin; Ju, Xuan; Wu, Hao; Dong, Weitong; Leung, Joyce C.; Hou, Xiaowen; Lee, Heewon; Granger, Alice; Paolillo, Joshua M.; Dimeo, Susan V.; Chen, Chengsheng; Wu, Linglin; Lorenz, Jon C.; Sarvestani, Max; Buono, Frederic; Frutos, Rogelio; Tampone, Thomas G.; Huang, Xiaojun; Zhang, Gulin; Wang, Yuwen; Spinelli, Earl; Lei, Zhen; Song, Jinhua J.
err分享
err收藏
Feed-Forward Neural Network for Predicting Enantioselectivity of the Asymmetric Negishi Reaction
errACS CENTRAL SCIENCE
IF10.4
err2023-08-24
err3
errOAAI
errCuomo, Abbigayle E.; Ibarraran, Sebastian; Sreekumar, Sanil; Li, Haote; Eun, Jungmin; Menzel, Jan Paul; Zhang, Pengpeng; Buono, Frederic; Song, Jinhua J.; Crabtree, Robert H.; Batista, Victor S.; Newhouse, Timothy R.
err分享
err收藏
Process Development of the BACE Inhibitors BI 1147560 BS and BI 1181181 MZ
errORGANIC PROCESS RESEARCH & DEVELOPMENT
IF3.5
err2022-12-08
err5
PREAI
errLi, Guisheng; Tan, Zhulin; Xu, Yibo; Sidhu, Kanwar P. S.; Qu, Bo; Herbage, Melissa A.; Eriksson, Magnus C.; Zeng, Xingzhong; Busacca, Carl A.; Desrosiers, Jean-Nicolas; Hampel, Thomas; Niemeier, Oliver; Reichel, Carsten; Dang, Mai Thi Quynh; Schoerer, Marvin; Kemmer, Dirk; Eick, Melanie; Werle, Holger; Kim, Soojin; Li, Zhibin; Venkatraman, Shankar; Jia, Lanqi; Claremon, David A.; Fuchs, Klaus; Heine, Niklas; Byrne, Denis; Narayanan, Bikshandarkoil; Sarvestani, Max; Johnson, Joe; Premasiri, Ajith; Nummy, Larry J.; Lorenz, Jon C.; Haddad, Nizar; Gonnella, Nina C.; Pennino, Scott; Krawiec, Mariusz; Senanayake, Chris H.; Buono, Frederic; Lee, Heewon; Hossain, Azad; Song, Jinhua J.; Reeves, Jonathan T.
err分享
err收藏
Enantioselective Synthesis of trans-Disubstituted Cyclopropyltrifluoroborate Building Blocks through Ru-Catalyzed Cyclopropanation
errORGANIC PROCESS RESEARCH & DEVELOPMENT
IF3.5
err2022-10-04
err2
PREAI
errNguyen, Thach; Sreekumar, Sanil; Wang, Shuai; Jiang, Qi; Montel, Florian; Buono, Frederic
err分享
err收藏
Recent Advances in Non-Precious Metal Catalysis
errORGANIC PROCESS RESEARCH & DEVELOPMENT
IF3.5
err2022-08-02
err1
PREAI
errWu, Hao; Qu, Bo; Nguyen, Thach; Lorenz, Jon C.; Buono, Frederic; Haddad, Nizar
err分享
err收藏
Discovery and Process Development of a Scalable Biocatalytic Kinetic Resolution toward Synthesis of a Sterically Hindered Chiral Ketone
errORGANIC PROCESS RESEARCH & DEVELOPMENT
IF3.5
err2022-05-17
err21
PREAI
errWamser, Nicole; Wu, Hao; Buono, Frederic; Brundage, Anthony; Ricci, Francesco; Lorenz, Jon C.; Wang, Jun; Haddad, Nizar; Paolillo, Joshua; Leung, Joyce C.; Lee, Heewon; Hossain, Azad
err分享
err收藏
Autonomous Multi-Step and Multi-Objective Optimization Facilitated by Real-Time Process Analytics
errADVANCED SCIENCE
IF14.1
err2022-02-01
err46
errOAAI
errSagmeister, Peter; Ort, Florian F.; Jusner, Clemens E.; Hebrault, Dominique; Tampone, Thomas; Buono, Frederic G.; Williams, Jason D.; Kappe, C. Oliver
err分享
err收藏

研究方向

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合作学者
合作期刊
R
Robert H. Crabtree
H 指数: 165 · 论文数: 1.2K
C
C. Oliver Kappe
H 指数: 98 · 论文数: 914
P
Peter Wipf
H 指数: 96 · 论文数: 1.0K
V
Víctor S. Batista
H 指数: 79 · 论文数: 631
P
Patrick J. Walsh
H 指数: 76 · 论文数: 696
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