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The inflammasome sensor NLRP3 interacts with REV7 to maintain genome integrity through homologous recombination 炎症小体传感器NLRP3通过与REV7相互作用，通过同源重组来维持基因组完整性。 Burlet, Delphine; Khan, Md Muntaz; Hacot, Sabine; Buthmann, Hannes; Bardoulet, Lea; Huber, Anne-Laure; Gorry, Julie; Foehr, Bastian; Lopez, Bernard S.; Coute, Yohann; Faesen, Alex C.; Geyer, Matthias; Tissier, Agnes; Petrilli, Virginie 分享 收藏
Genome rearrangements induced by the stimulation of end-joining of DNA double strand breaks through multiple phosphorylation of MRE11 by the kinase PKB/AKT1 通过激酶PKB/AKT1对MRE11的多位点磷酸化，诱导DNA双链断裂末端连接的基因组重排。 Guirouilh-Barbat, Josee; Boueya, Iman Litchy; Gelot, Camille; Pennarun, Gaelle; Granotier-Beckers, Christine; Dardillac, Elodie; Yu, Wei; Lescale, Chloe; Rass, Emilie; Ariste, Olivier; Siaud, Nicolas; Renouf, Benjamin; Millet, Armel; Puget, Nadine; Bertrand, Pascale; de la Grange, Pierre; Brunet, Erika; Deriano, Ludovic; Lopez, Bernard S. 分享 收藏
Human RAD52 stimulates the RAD51-mediated homology search Muhammad, Ali Akbar; Basto, Clara; Peterlini, Thibaut; Guirouilh-Barbat, Jos ee; Thomas, Melissa; Veaute, Xavier; Busso, Didier; Lopez, Bernard; Mazon, Gerard; Le Cam, Eric; Masson, Jean-Yves; Dupaigne, Pauline 分享 收藏
In vivo reduction of RAD51-mediated homologous recombination triggers aging but impairs oncogenesis 体内减少RAD51-mediated同源重组会触发衰老，但会损害肿瘤发生 Matos-Rodrigues, Gabriel; Barroca, Vilma; Muhammad, Ali-Akbar; Dardillac, Elodie; Allouch, Awatef; Koundrioukoff, Stephane; Lewandowski, Daniel; Despras, Emmanuelle; Guirouilh-Barbat, Josee; Frappart, Lucien; Kannouche, Patricia; Dupaigne, Pauline; Le Cam, Eric; Perfettini, Jean-Luc; Romeo, Paul-Henri; Debatisse, Michelle; Jasin, Maria; Livera, Gabriel; Martini, Emmanuelle; Lopez, Bernard S. 分享 收藏
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Nitrative Modification of Caveolin-3: A Novel Mechanism of Cardiac Insulin Resistance and a Potential Therapeutic Target Against Ischemic Heart Failure in Prediabetic Animals Meng, Zhijun; Zhang, Zhen; Zhao, Jianli; Liu, Caihong; Yao, Peng; Zhang, Ling; Xie, Dina; Lau, Wayne Bond; Tsukuda, Jumpei; Christopher, Theodore A.; Lopez, Bernard; Zhu, Di; Liu, Demin; Zhang, John Ry; Gao, Erhe; Ischiropoulos, Harry; Koch, Walter; Ma, Xinliang; Wang, Yajing 分享 收藏
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A noncanonical response to replication stress protects genome stability through ROS production, in an adaptive manner Ragu, Sandrine; Droin, Nathalie; Matos-Rodrigues, Gabriel; Barascu, Aurelia; Caillat, Sylvain; Zarkovic, Gabriella; Siberchicot, Capucine; Dardillac, Elodie; Gelot, Camille; Guirouilh-Barbat, Josee; Radicella, J. Pablo; Ishchenko, Alexander A.; Ravanat, Jean-Luc; Solary, Eric; Lopez, Bernard S. 分享 收藏
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Institutional solutions addressing disparities in compensation and advancement of emergency medicine physicians: A critical appraisal of gaps and associated recommendations Madsen, Tracy E.; Heron, Sheryl; Lall, Michelle D.; Blomkalns, Andra; Arbelaez, Christian; Lopez, Bernard; Lin, Michelle; Rounds, Kirsten; Sethuraman, Kinjal N.; Safdar, Basmah 分享 收藏
RAD51 protects against nonconservative DNA double-strand break repair through a nonenzymatic function So, Ayeong; Dardillac, Elodie; Muhammad, Ali; Chailleux, Catherine; Sesma-Sanz, Laura; Ragu, Sandrine; Le Cam, Eric; Canitrot, Yvan; Masson, Jean Yves; Dupaigne, Pauline; Lopez, Bernard S.; Guirouilh-Barbat, Josee 分享 收藏
Ischemic Heart-Derived Small Extracellular Vesicles Impair Adipocyte Function Lu, Gan; Liu, Demin; Xie, Dina; Bond Lau, Wayne; Liu, Jing; Christopher, Theodore A.; Lopez, Bernard; Liu, Lian; Hu, Hang; Yao, Peng; He, Yarong; Gao, Erhe; Koch, Walter J.; Zhao, Jianli; Ma, Xin-Liang; Cao, Yu; Wang, Yajing 分享 收藏
Phospho-Ku70 induced by DNA damage interacts with RNA Pol II and promotes the formation of phospho-53BP1 foci to ensure optimal cNHEJ Schellenbauer, Amelie; Guilly, Marie-Noelle; Grall, Romain; Le Bars, Romain; Paget, Vincent; Kortulewski, Thierry; Sutcu, Haser; Mathe, Cecile; Hullo, Marie; Biard, Denis; Leteurtre, Francois; Barroca, Vilma; Corre, Youenn; Irbah, Lamya; Rass, Emilie; Theze, Benoit; Bertrand, Pascale; Demmers, Jeroen A. A.; Guirouilh-Barbat, Josee; Lopez, Bernard S.; Chevillard, Sylvie; Delic, Jozo 分享 收藏
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Targeting acute myeloid leukemia dependency on VCP-mediated DNA repair through a selective second-generation small-molecule inhibitor 通过选择性第二代小分子抑制剂靶向急性髓系白血病对VCP介导的DNA修复的依赖性 Roux, Blandine; Vaganay, Camille; Vargas, Jesse D.; Alexe, Gabriela; Benaksas, Chaima; Pardieu, Bryann; Fenouille, Nina; Ellegast, Jana M.; Malolepsza, Edyta; Ling, Frank; Rol, Gaetano Soda; Ross, Linda; Pikman, Yana; Conwa, Amy S. Y.; Tang, Yangzhong; Wu, Tony; Anderson, Daniel J.; Le Moigne, Ronan; Zhou, Ha N-Jie; Luciano, Frederic; Hartigan, Christina R.; Galinsky, Ilene; DeAngelo, Daniel J.; Stone, Richard M.; Auberger, Patrick; Schenone, Monica; Rr, Steven A. Ca; Guirouilh-Barbat, Josee; Lopez, Bernard; Khaled, Mehdi; Lage, Kasper; Hermine, Olivier; Hemann, Michael T.; Puissant, Alexandre; Stegmaier, Kimberly; Benajiba, Lina 分享 收藏
C1q Complement/Tumor Necrosis Factor-Associated Proteins in Cardiovascular Disease and COVID-19 Xie, Yaoli; Meng, Zhijun; Gao, Jia; Liu, Caihong; Wang, Jing; Guo, Rui; Zhao, Jianli; Lopez, Bernard; Christopher, Theodore; Lee, Daniel; Ma, Xinliang; Wang, Yajing 分享 收藏
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