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O

Orlando D. Schärer

institute for basic science - korea (ibs)

46H指数
165论文数
9.7K被引数
收录论文 88
发表时间
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The interaction of XPG with TFIIH through p62 and XPD is required for the completion of nucleotide excision repairXPG通过p62和XPD与TFIIH的相互作用对于完成核苷酸切除修复是必需的
errNucleic Acids Research
IF13.1
err2026-02-27
err0
PREAI
errKim, Mihyun; Jeong, Eunwoo; Park, Jiyoung; D'Souza, Areetha; Tsai, Miaw-Sheue; Yan, Chunli; Ivanov, Ivaylo; Chazin, Walter J.; Kim, Hyun Suk; Scharer, Orlando D.
err分享
err收藏
Molecular basis of DNA cross-linking by bacteria细菌DNA交联的分子基础
errSCIENCE
IF45.8
err2025-12-04
err0
PREAI
errScharer, Orlando D.
err分享
err收藏
Proteomic discovery of DEK and NUMA1 as new players in UV-induced DNA damage repair mechanisms蛋白质组学发现DEK和NUMA1作为UV诱导的DNA损伤修复机制中的新参与者
errCell Death Discovery
IF7
err2025-11-24
err0
errOAAI
errNamwoo Kim; Mihyun Kim; Eunwoo Jeong; Jung-Eun Yeo; Byung-gyu Kim; Kyungjae Myung; Orlando D. Schärer; Kyoo-young Lee
err分享
err收藏
RNF4 and USP7 coordinate spatial regulation of SLX4 stability within the PML nuclear bodiesRNF4和USP7协同调控PML核体中SLX4稳定性的空间分布
errNUCLEIC ACIDS RESEARCH
IF13.1
err2025-10-14
err0
PREAI
errJung, Eunyoung; Kim, Myung-Jin; Scharer, Orlando D.; Kim, Yonghwan
err分享
err收藏
A splicing variant in XPA results in delayed onset of clinical features of xeroderma pigmentosumXPA基因的一个剪接变异导致着色性干皮病临床特征的延迟出现。
errJournal of Investigative Dermatology
IF5.7
err2025-09-24
err0
PREAI
errAnita van den Heuvel; Annelotte P. Wondergem; Mihyun Kim; Isa Breet; Hyun Suk Kim; Heather Fawcett; Hiva Fassihi; Alan R. Lehmann; Orlando D. Schärer; Martijn S. Luijsterburg
err分享
err收藏
XPC-RAD23B enhances UV-DDB binding to DNA to facilitate lesion search in nucleotide excision repairXPC-RAD23B通过增强UV-DDB与DNA的结合，促进核苷酸切除修复中的损伤搜索。
errNUCLEIC ACIDS RESEARCH
IF13.1
err2025-06-24
err1
errOAAI
errAn, Soyeong; Kusakabe, Masayuki; Kim, Hyun-Suk; Kozono, Hidetsugu; Cheon, Na Young; Kim, Jeongeun; Kang, Jieun; Jang, Sunbok; Sugasawa, Kaoru; Scharer, Orlando D.; Lee, Ja Yil
err分享
err收藏
Protein-protein interactions in the core nucleotide excision repair pathway核心核苷酸切除修复途径中的蛋白质-蛋白质相互作用
errDNA REPAIR
IF2.7
err2024-09-01
err1
PREAI
errD'Souza, Areetha; Kim, Mihyun; Chazin, Walter J.; Scharer, Orlando D.
err分享
err收藏
XPA tumor variant leads to defects in NER that sensitize cells to cisplatin
errNAR CANCER
IF3.2
err2024-03-18
err1
errOAAI
errBlee, Alexandra M.; Gallagher, Kaitlyn S.; Kim, Hyun-Suk; Kim, Mihyun; Kharat, Suhas S.; Troll, Christina R.; D'Souza, Areetha; Park, Jiyoung; Neufer, P. Drew; Scharer, Orlando D.; Chazin, Walter J.
err分享
err收藏
Trabectedin derails transcription-coupled nucleotide excision repair to induce DNA breaks in highly transcribed genes
errNATURE COMMUNICATIONS
IF15.7
err2024-02-15
err2
errOAAI
errSon, Kook; Takhaveev, Vakil; Mor, Visesato; Yu, Hobin; Dillier, Emma; Zilio, Nicola; Pullen, Nikolai J. L.; Ivanov, Dmitri; Ulrich, Helle D.; Sturla, Shana J.; Scharer, Orlando D.
err分享
err收藏
Detection of oxaliplatin- and cisplatin-DNA lesions requires different global genome repair mechanisms that affect their clinical efficacy
errNAR CANCER
IF3.2
err2023-12-05
err3
errOAAI
errSlyskova, Jana; Muniesa-Vargas, Alba; da Silva, Israel Tojal; Drummond, Rodrigo; Park, Jiyeong; Hackes, David; Poetsch, Isabella; Ribeiro-Silva, Cristina; Moretton, Amandine; Heffeter, Petra; Scharer, Orlando D.; Vermeulen, Wim; Lans, Hannes; Loizou, Joanna, I
err分享
err收藏
Alkylation of nucleobases by 2-chloro-N,N-diethylethanamine hydrochloride (CDEAH) sensitizes PARP1-deficient tumors
errNAR CANCER
IF3.2
err2023-08-07
err0
errOAAI
errWie, Minwoo; Khim, Keon Woo; Groehler IV, Arnold S.; Heo, Soomin; Woo, Junhyeok; Son, Kook; Lee, Eun A.; Ra, Jae Sun; Hong, Sung You; Scharer, Orlando D.; Choi, Jang Hyun; Myung, Kyungjae
err分享
err收藏
Development of Comprehensive Ultraperformance Liquid Chromatography-High-Resolution Mass Spectrometry Assays to Quantitate Cisplatin-Induced DNA-DNA Cross-Links
errCHEMICAL RESEARCH IN TOXICOLOGY
IF3.8
err2023-05-19
err3
errOAAI
errGroehler, Arnold S.; Maratova, Asema; Dao, Nhat Mai; Mahkmut, Anuar; Scharer, Orlando D.
err分享
err收藏
MSH2-MSH3 promotes DNA end resection during homologous recombination and blocks polymerase theta-mediated end-joining through interaction with SMARCAD1 and EXO1
errNUCLEIC ACIDS RESEARCH
IF13.1
err2023-05-04
err7
errOAAI
errOh, Jung-Min; Kang, Yujin; Park, Jumi; Sung, Yubin; Kim, Dayoung; Seo, Yuri; Lee, Eun A.; Ra, Jae Sun; Amarsanaa, Enkhzul; Park, Young-Un; Lee, Seon Young; Hwang, Jung Me; Kim, Hongtae; Scharer, Orlando; Cho, Seung Woo; Lee, Changwook; Takata, Kei-ichi; Lee, Ja Yil; Myung, Kyungjae
err分享
err收藏
A disease-associated XPA allele interferes with TFIIH binding and primarily affects transcription-coupled nucleotide excision repair
errPROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
IF9.1
err2023-03-09
err7
errOAAI
errvan den Heuvel, Diana; Kim, Mihyun; Wondergem, Annelotte P.; van der Meer, Paula J.; Witkamp, Myrese; Lambregtse, Ferdy; Kim, Hyun-Suk; Kan, Folkert; Apelt, Katja; Kragten, Angela; Gonzalez-Prieto, Roman; Vertegaal, Alfred C. O.; Yeo, Jung-Eun; Kim, Byung-Gyu; van Doorn, Remco; Scharer, Orlando D.; Luijsterburg, Martijn S.
err分享
err收藏
EEPD1 promotes repair of oxidatively-stressed replication forks
errNAR CANCER
IF3.2
err2023-01-18
err7
errOAAI
errJaiswal, Aruna S.; Kim, Hyun-Suk; Scharer, Orlando D.; Sharma, Neelam; Williamson, Elizabeth A.; Srinivasan, Gayathri; Phillips, Linda; Kong, Kimi; Arya, Shailee; Misra, Anurag; Dutta, Arijit; Gupta, Yogesh; Walter, Christi A.; Burma, Sandeep; Narayan, Satya; Sung, Patrick; Nickoloff, Jac A.; Hromas, Robert
err分享
err收藏
ZNF212 promotes genomic integrity through direct interaction with TRAIP
errNUCLEIC ACIDS RESEARCH
IF13.1
err2023-01-03
err0
errOAAI
errChung, Hee Jin; Lee, Joo Rak; Kim, Tae Moon; Kim, Soomi; Park, Kibeom; Kim, Myung-Jin; Jung, Eunyoung; Kim, Subin; Lee, Eun A.; Rae, Jae Sun; Hwang, Sunyoung; Lee, Ja Yil; Scharer, Orlando D.; Kim, Yonghwan; Myung, Kyungjae; Kim, Hongtae
err分享
err收藏
Two interaction surfaces between XPA and RPA organize the preincision complex in nucleotide excision repair
errPROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
IF9.1
err2022-08-15
err23
errOAAI
errKim, Mihyun; Kim, Hyun-Suk; D'Souza, Areetha; Gallagher, Kaitlyn; Jeong, Eunwoo; Le Meur, Kateryna Ogorodnik; Tsai, Chi-Lin; Tsai, Miaw-Sheue; Kee, Minyong; Tainer, John A.; Yeo, Jung-Eun; Chazin, Walter J.; Scharer, Orlando D.
err分享
err收藏
XPC-PARP complexes engage the chromatin remodeler ALC1 to catalyze global genome DNA damage repair
errNATURE COMMUNICATIONS
IF15.7
err2022-08-13
err11
errOAAI
errBlessing, Charlotte; Apelt, Katja; van den Heuvel, Diana; Gonzalez-Leal, Claudia; Rother, Magdalena B.; van der Woude, Melanie; Gonzalez-Prieto, Roman; Yifrach, Adi; Parnas, Avital; Shah, Rashmi G.; Kuo, Tia Tyrsett; Boer, Daphne E. C.; Cai, Jin; Kragten, Angela; Kim, Hyun-Suk; Scharer, Orlando D.; Vertegaal, Alfred C. O.; Shah, Girish M.; Adar, Sheera; Lans, Hannes; van Attikum, Haico; Ladurner, Andreas G.; Luijsterburg, Martijn S.
err分享
err收藏
Transcriptional Perturbations of 2,6-Diaminopurine and 2-Aminopurine
errACS CHEMICAL BIOLOGY
IF3.8
err2022-06-14
err8
errOAAI
errTan, Ying; You, Changjun; Park, Jiyeong; Kim, Hyun Suk; Guo, Su; Scharer, Orlando D.; Wang, Yinsheng
err分享
err收藏
Polycarcin V induces DNA damage response and enables the profiling of DNA-binding proteins
errNATIONAL SCIENCE REVIEW
IF17.1
err2022-03-11
err4
errOAAI
errYue, Zongwei; Wu, Fan; Guo, Fusheng; Park, Jiyeong; Wang, Jin; Zhang, Liyun; Liao, Daohong; Li, Wenyang; Scharer, Orlando D.; Lei, Xiaoguang
err分享
err收藏

研究方向

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合作学者
合作期刊
F
F. Peter Guengerich
H 指数: 140 · 论文数: 1.2K
J
John A. Tainer
H 指数: 123 · 论文数: 807
J
Jan H.J. Hoeijmakers
H 指数: 122 · 论文数: 555
G
Gerhard Wagner
H 指数: 119 · 论文数: 958
W
William S. Lane
H 指数: 100 · 论文数: 314
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