Rasmus Hartmann‐Petersen

university of copenhagen

40H指数

142论文数

4.8K被引数

收录论文 67

发表时间

Autoinhibition of untimely DNA binding by structural disorder in the full-length peroxisome proliferator-activated receptors (PPARs)全长过氧化物增殖物激活受体(PPARs)中结构无序导致的非时序DNA结合的自抑制

Nature Communications

IF15.7

2026-08-26

OAAI

Milena R. Lalic; Elisabeth G. K. Thomsen; F. Emil Thomasen; Aditya Udupa; Emma Salehian Andersen; Sonja Kuppermann; Casper G. Christensen; Emma Holm-Olesen; Daniel Saar; Andreas Prestel; Lukas W. Bauer; Joseph McKenna; Johan G. Olsen; Susanne Mandrup; Rasmus Hartmann-Petersen; Cy M. Jeffries; Max V. Staller; Kresten Lindorff-Larsen; Birthe B. Kragelund

Blocking protein quality control degradation leads to structural stabilization of DHFR indel variants 阻断蛋白质质量控制降解导致二氢叶酸还原酶插入缺失变异体的结构稳定化

the febs journal

IF0

2026-06-16

OAAI

Sven Larsen-Ledet; Caroline H. Suhr; Sarah Gersing; Celeste M. Hackney; Amelie Stein; Kaare Teilum; Rasmus Hartmann-Petersen

Proteasomal control of transcription factors: mechanisms, regulation and dysregulation 蛋白酶体对转录因子的调控：机制、调控与失调

Cellular and Molecular Life Sciences

IF6.2

2026-03-01

OAAI

Fia B. Larsen; Birthe B. Kragelund; Kresten Lindorff-Larsen; Pétur O. Heidarsson; Rasmus Hartmann-Petersen

A near-complete map of human cytosolic degrons and their relevance for disease 人类胞质degrons的近乎完整的地图及其与疾病的相关性

Science Advances

IF12.5

2026-02-06

OAAI

Vasileios Voutsinos; Kristoffer E. Johansson; Fia B. Larsen; Martin Grønbæk-Thygesen; Nicolas Jonsson; Emma Holm-Olesen; Giulio Tesei; Amelie Stein; Douglas M. Fowler; Kresten Lindorff-Larsen; Rasmus Hartmann-Petersen

The Importance of UBQLN2 Ubiquitylation for Its Turnover and Localization UBQLN2泛素化对其周转和定位的重要性

BIOCHEMISTRY

IF3

2025-12-01

PREAI

Gronbaek-Thygesen, Martin; Kampmeyer, Caroline; Eschger, Paula; Tatham, Michael H.; Arts, Marloes; Hofmann, Kay; Lindorff-Larsen, Kresten; Boomsma, Wouter; Hartmann-Petersen, Rasmus

Extreme multivalency and a composite short linear motif facilitate PCNA-binding, localisation and abundance of p21 (CDKN1A)极度的多价性和一个复合的短线性基序促进了PCNA结合、定位和p21 (CDKN1A)的丰度。

FEBS JOURNAL

IF4.2

2025-05-20

OAAI

Signe Simonsen; Fia B. Larsen; Caroline K. Søgaard; Nicolas Jonsson; Kresten Lindorff-Larsen; Per Bruheim; Marit Otterlei; Rasmus Hartmann-Petersen; Birthe B. Kragelund

PRKN-linked familial Parkinson's disease: cellular and molecular mechanisms of disease-linked variants PRKN连锁家族性帕金森病: 疾病相关变异的细胞和分子机制

CELLULAR AND MOLECULAR LIFE SCIENCES

IF6.2

2024-05-20

OAAI

Clausen, Lene; Okarmus, Justyna; Voutsinos, Vasileios; Meyer, Morten; Lindorff-Larsen, Kresten; Hartmann-Petersen, Rasmus

Deep mutational scanning reveals a correlation between degradation and toxicity of thousands of aspartoacylase variants

NATURE COMMUNICATIONS

IF15.7

2024-05-13

OAAI

Gronbaek-Thygesen, Martin; Voutsinos, Vasileios; Johansson, Kristoffer E.; Schulze, Thea K.; Cagiada, Matteo; Pedersen, Line; Clausen, Lene; Nariya, Snehal; Powell, Rachel L.; Stein, Amelie; Fowler, Douglas M.; Lindorff-Larsen, Kresten; Hartmann-Petersen, Rasmus

Characterizing glucokinase variant mechanisms using a multiplexed abundance assay 使用多重丰度测定法表征葡萄糖激酶变体机制

GENOME BIOLOGY

IF9.4

2024-04-16

OAAI

Gersing, Sarah; Schulze, Thea K.; Cagiada, Matteo; Stein, Amelie; Roth, Frederick P.; Lindorff-Larsen, Kresten; Hartmann-Petersen, Rasmus

Cellular and molecular mechanisms of aspartoacylase and its role in Canavan disease 天冬氨酸酰化酶的细胞和分子机制及其在Canavan病中的作用

CELL AND BIOSCIENCE

IF6.2

2024-04-06

OAAI

Gronbaek-Thygesen, Martin; Hartmann-Petersen, Rasmus

A mutational atlas for Parkin proteostasis

NATURE COMMUNICATIONS

IF15.7

2024-02-20

OAAI

Clausen, Lene; Voutsinos, Vasileios; Cagiada, Matteo; Johansson, Kristoffer E.; Gronbaek-Thygesen, Martin; Nariya, Snehal; Powell, Rachel L.; Have, Magnus K. N.; Oestergaard, Vibe H.; Stein, Amelie; Fowler, Douglas M.; Lindorff-Larsen, Kresten; Hartmann-Petersen, Rasmus

Discovering functionally important sites in proteins 发现蛋白质中功能重要的位点

NATURE COMMUNICATIONS

IF15.7

2023-07-13

OAAI

Cagiada, Matteo; Bottaro, Sandro; Lindemose, Soren; Schenstrom, Signe M.; Stein, Amelie; Hartmann-Petersen, Rasmus; Lindorff-Larsen, Kresten

Lysine deserts prevent adventitious ubiquitylation of ubiquitin-proteasome components 赖氨酸沙漠阻止泛素-蛋白酶体组分的不定泛素化

CELLULAR AND MOLECULAR LIFE SCIENCES

IF6.2

2023-05-09

OAAI

Kampmeyer, Caroline; Gronbaek-Thygesen, Martin; Oelerich, Nicole; Tatham, Michael H.; Cagiada, Matteo; Lindorff-Larsen, Kresten; Boomsma, Wouter; Hofmann, Kay; Hartmann-Petersen, Rasmus

A comprehensive map of human glucokinase variant activity

GENOME BIOLOGY

IF9.4

2023-04-26

OAAI

Gersing, Sarah; Cagiada, Matteo; Gebbia, Marinella; Gjesing, Anette P.; Cote, Atina G.; Seesankar, Gireesh; Li, Roujia; Tabet, Daniel; Weile, Jochen; Stein, Amelie; Gloyn, Anna L.; Hansen, Torben; Roth, Frederick P.; Lindorff-Larsen, Kresten; Hartmann-Petersen, Rasmus

HSP70-binding motifs function as protein quality control degrons HSP70-binding基序作为蛋白质质量控制的功能

CELLULAR AND MOLECULAR LIFE SCIENCES

IF6.2

2023-01-07

OAAI

Abildgaard, Amanda B.; Voutsinos, Vasileios; Petersen, Soren D.; Larsen, Fia B.; Kampmeyer, Caroline; Johansson, Kristoffer E.; Stein, Amelie; Ravid, Tommer; Andreasson, Claes; Jensen, Michael K.; Lindorff-Larsen, Kresten; Hartmann-Petersen, Rasmus

How phosphorylation impacts intrinsically disordered proteins and their function 磷酸化如何影响内在无序的蛋白质及其功能

ESSAYS IN BIOCHEMISTRY

IF5.7

2022-12-16

OAAI

Newcombe, Estella A.; Delaforge, Elise; Hartmann-Petersen, Rasmus; Skriver, Karen; Kragelund, Birthe B.

Conserved degronome features governing quality control associated proteolysis 控制质量控制相关蛋白水解的保守degronome特征

NATURE COMMUNICATIONS

IF15.7

2022-12-08

OAAI

Mashahreh, Bayan; Armony, Shir; Johansson, Kristoffer Ene; Chappleboim, Alon; Friedman, Nir; Gardner, Richard G.; Hartmann-Petersen, Rasmus; Lindorff-Larsen, Kresten; Ravid, Tommer

14-fold increased prevalence of rare glucokinase gene variant carriers in unselected Danish patients with newly diagnosed type 2 diabetes

DIABETES RESEARCH AND CLINICAL PRACTICE

IF7.4

2022-12-01

OAAI

Gjesing, Anette P.; Engelbrechtsen, Line; Thuesen, Anne Cathrine B.; Have, Christian T.; Hollensted, Mette; Grarup, Niels; Linneberg, Allan; Nielsen, Jens Steen; Christensen, Lotte B.; Thomsen, Reimar W.; Johansson, Kristoffer E.; Cagiada, Matteo; Gersing, Sarah; Hartmann-Petersen, Rasmus; Lindorff-Larsen, Kresten; Vaag, Allan; Sorensen, Henrik T.; Brandslund, Ivan; Beck-Nielsen, Henning; Pedersen, Oluf; Rungby, Jorgen; Hansen, Torben

Lynch syndrome, molecular mechanisms and variant classification Lynch综合征，分子机制和变异分类

BRITISH JOURNAL OF CANCER

IF6.8

2022-11-24

OAAI

Abildgaard, Amanda B.; Nielsen, Sofie, V; Bernstein, Inge; Stein, Amelie; Lindorff-Larsen, Kresten; Hartmann-Petersen, Rasmus

A context-dependent and disordered ubiquitin-binding motif

CELLULAR AND MOLECULAR LIFE SCIENCES

IF6.2

2022-08-16

OAAI

Dreier, Jesper E.; Prestel, Andreas; Martins, Joao M.; Brondum, Sebastian S.; Nielsen, Olaf; Garbers, Anna E.; Suga, Hiroaki; Boomsma, Wouter; Rogers, Joseph M.; Hartmann-Petersen, Rasmus; Kragelund, Birthe B.

研究方向