Jean‐Baptiste Charbonnier

universite paris cite

36H指数

147论文数

3.8K被引数

收录论文 56

发表时间

Characterization of a Ku-binding motif in the C-terminal region of RAG2 RAG2 C末端区域中Ku结合基序的表征

DNA Repair

IF2.7

2026-09-29

PREAI

Tadi, Satish K.; Gesnik, Armelle; Nabhan, Lea; Frit, Philippe; Iehl, Florence; Ropars, Virginie; Dingli, Florent; Loew, Damarys; Calsou, Patrick; Callebaut, Isabelle; Cuniasse, Philippe; Charbonnier, Jean-Baptiste; de Villartay, Jean-Pierre

Rap1-mediated steric hindrance protects telomeres from MRX sensing Rap1介导的空间位阻保护端粒免受MRX传感

NATURE STRUCTURAL & MOLECULAR BIOLOGY

IF10.1

2026-05-20

OAAI

Stefano Mattarocci; Giordano Reginato; Elda Cannavo; Florian Roisné-Hamelin; Robert Gnügge; Alice Deshayes; Sabrina Pobiega; Olivier Alibert; Vincent Morin; Virginie Ropars; Johannes Mehringer; Vincent Geli; Philippe Cuniasse; Jean-Baptiste Charbonnier; Lorraine S. Symington; Petr Cejka; Stéphane Marcand

Structural basis of Ku-mediated activation of WRN exonuclease activity Ku介导的WRN外切酶活性激活的结构基础

Nature Communications

IF15.7

2026-05-13

OAAI

Sayma Zahid; Jeanne Chauvat; Ilaria Ceppi; Floriana Cappiello; Benedetta Perdichizzi; Philippe Frit; Dennis Gomez; Steven W. Hardwick; Pierre Legrand; Julien Karazi; Sonia Baconnais; Gérard Pehau-Arnaudet; Sébastien Britton; Jean-Baptiste Charbonnier; Amanda K. Chaplin; Pietro Pichierri; Petr Cejka; Patrick Calsou; Virginie Ropars

The tRNA moieties of both aminoacyl-tRNA substrates of a cyclodipeptide synthase share a common binding site, as revealed by RNA microhelices mimicking tRNA acceptor arms 环二肽合酶的两种氨酰-tRNA底物的tRNA基团共享一个共同的结合位点，如模拟tRNA受体臂的RNA微螺旋所示。

Nucleic Acids Research

IF13.1

2026-04-07

OAAI

Zahra Marouf; Carine Tellier-Lebegue; Matthieu Glousieau; Nelly Morellet; Philippe Cuniasse; Alexa Bourand-Plantefol; Stéphane Plancqueel; Ikram Mahmoudi; Jessica Andreani; Pierre Legrand; Virginie Ropars; Rémi Ruedas; Léa-Fleur Hermouet; Mireille Moutiez; Naïma Nhiri; Matthieu Fonvielle; Stéphane Bressanelli; Takayuki Katoh; Paloma Fernandez Varela; Ewen Lescop; Jean-Baptiste Charbonnier; Muriel Gondry; null

Cryo-EM structures of NHEJ assemblies with nucleosomes NHEJ组装体与核小体的冷冻电镜结构

Nature Communications

IF15.7

2025-12-24

OAAI

Chloe Hall; Philippe Frit; Antonia Kefala-Stavridi; Amandine Pelletier; Steven W. Hardwick; Himani Amin; Matthew K. Bilyard; Taiana Maia De Oliviera; Ammarah Tariq; Sayma Zahid; Dimitri Y. Chirgadze; Shankar Balasubramanian; Katheryn Meek; Virginie Ropars; Jean-Baptiste Charbonnier; Mauro Modesti; Patrick Calsou; Sébastien Britton; Tom L. Blundell; Thomas Schalch; Amanda K. Chaplin

Design; synthesis; and structure–activity relationship studies of 4-substituted phenylpyrazolidinone derivatives as potent Ku70/80 targeted DNA-PK inhibitors 设计、合成及4-取代苯基吡唑烷酮衍生物作为强效Ku70/80靶向DNA-PK抑制剂的构效关系研究

RSC Med. Chem.

IF3.6

2025-09-27

OAAI

Narva Deshwar Kushwaha; Pamela VanderVere-Carozza; Tyler L. Vernon; Pamela L. Mendoza-Munoz; Jitender D. Gaddameedi; Karim Ben Ali Gacem; Joseph Engel; Jean-Baptiste Charbonnier; Navnath S. Gavande; John J. Turchi

Structural and functional insights into the interaction between Ku70/80 and Pol X family polymerases in NHEJ Ku70/80与Pol X家族聚合酶在NHEJ中的相互作用的结构与功能见解

NATURE COMMUNICATIONS

IF15.7

2025-05-06

OAAI

Frit, Philippe; Amin, Himani; Zahid, Sayma; Barboule, Nadia; Hall, Chloe; Matharu, Gurdip; Hardwick, Steven W.; Chauvat, Jeanne; Britton, Sebastien; Chirgadze, Dima Y.; Ropars, Virginie; Charbonnier, Jean-Baptiste; Calsou, Patrick; Chaplin, Amanda K.

FIGNL1-FIRRM is essential for meiotic recombination and prevents DNA damage-independent RAD51 and DMC1 loading

NATURE COMMUNICATIONS

IF15.7

2024-08-15

OAAI

Zainu, Akbar; Dupaigne, Pauline; Bouchouika, Soumya; Cau, Julien; Clement, Julie A. J.; Auffret, Pauline; Ropars, Virginie; Charbonnier, Jean-Baptiste; de Massy, Bernard; Mercier, Raphael; Kumar, Rajeev; Baudat, Frederic

HLTF disrupts Cas9-DNA post-cleavage complexes to allow DNA break processing

NATURE COMMUNICATIONS

IF15.7

2024-07-10

OAAI

Reginato, Giordano; Dello Stritto, Maria Rosaria; Wang, Yanbo; Hao, Jingzhou; Pavani, Raphael; Schmitz, Michael; Halder, Swagata; Morin, Vincent; Cannavo, Elda; Ceppi, Ilaria; Braunshier, Stefan; Acharya, Ananya; Ropars, Virginie; Charbonnier, Jean-Baptiste; Jinek, Martin; Nussenzweig, Andre; Ha, Taekjip; Cejka, Petr

Uncoupling programmed DNA cleavage and repair scrambles the Paramecium somatic genome

CELL REPORTS

IF6.9

2024-04-01

OAAI

Bischerour, Julien; Arnaiz, Olivier; Zangarelli, Coralie; Regnier, Vinciane; Iehl, Florence; Ropars, Virginie; Charbonnier, Jean -Baptiste; Betermier, Mireille

Structural and functional basis of inositol hexaphosphate stimulation of NHEJ through stabilization of Ku-XLF interaction

NUCLEIC ACIDS RESEARCH

IF13.1

2023-10-23

OAAI

Kefala Stavridi, Antonia; Gontier, Amandine; Morin, Vincent; Frit, Philippe; Ropars, Virginie; Barboule, Nadia; Racca, Carine; Jonchhe, Sagun; Morten, Michael J.; Andreani, Jessica; Rak, Alexey; Legrand, Pierre; Bourand-Plantefol, Alexa; Hardwick, Steven W.; Chirgadze, Dimitri Y.; Davey, Paul; De Oliveira, Taiana Maia; Rothenberg, Eli; Britton, Sebastien; Calsou, Patrick; Blundell, Tom L.; Varela, Paloma F.; Chaplin, Amanda K.; Charbonnier, Jean-Baptiste

RNA:DNA hybrids from Okazaki fragments contribute to establish the Ku-mediated barrier to replication-fork degradation

MOLECULAR CELL

IF16.6

2023-04-01

OAAI

Audoynaud, Charlotte; Schirmeisen, Kamila; Saada, Anissia Ait; Gesnik, Armelle; Fernandez-Varela, Paloma; Boucherit, Virginie; Ropars, Virginie; Chaudhuri, Anusha; Freon, Karine; Charbonnier, Jean-Baptiste; Lambert, Sarah A. E.

Characterization of a Highly Conserved Binding Site of Mlh1 Required for Exonuclease I-Dependent Mismatch Repair

MOLECULAR AND CELLULAR BIOLOGY

IF2.7

2023-03-21

OAAI

Dherin, Claudine; Gueneau, Emeric; Francin, Mathilde; Nunez, Marcela; Miron, Simona; Liberti, Sascha Emilie; Rasmussen, Lene Juel; Zinn-Justin, Sophie; Gilquin, Bernard; Charbonnier, Jean-Baptiste; Boiteux, Serge

Tandem regulation of MutS activity by ATP and DNA during MMR initiation

NATURE STRUCTURAL & MOLECULAR BIOLOGY

IF10.1

2022-01-13

PREAI

Charbonnier, Jean Baptiste

Cryo-EM of NHEJ supercomplexes provides insights into DNA repair

MOLECULAR CELL

IF16.6

2021-08-01

OAAI

Chaplin, Amanda K.; Hardwick, Steven W.; Stavridi, Antonia Kefala; Buehl, Christopher J.; Goff, Noah J.; Ropars, Virginie; Liang, Shikang; De Oliveira, Taiana Maia; Chirgadze, Dimitri Y.; Meek, Katheryn; Charbonnier, Jean-Baptiste; Blundell, Tom L.

FAN1-MLH1 interaction affects repair of DNA interstrand cross-links and slipped-CAG/CTG repeats

SCIENCE ADVANCES

IF12.5

2021-07-30

OAAI

Porro, Antonio; Mohiuddin, Mohiuddin; Zurfluh, Christina; Spegg, Vincent; Dai, Jingqi; Iehl, Florence; Ropars, Virginie; Collotta, Giulio; Fishwick, Keri M.; Mozaffari, Nour L.; Guerois, Raphael; Jiricny, Josef; Altmeyer, Matthias; Charbonnier, Jean-Baptiste; Pearson, Christopher E.; Sartori, Alessandro A.

Molecular basis of the dual role of the Mlh1-Mlh3 endonuclease in MMR and in meiotic crossover formation

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2021-06-04

OAAI

Dai, Jingqi; Sanchez, Aurore; Adam, Celine; Ranjha, Lepakshi; Reginato, Giordano; Chervy, Pierre; Tellier-Lebegue, Carine; Andreani, Jessica; Guerois, Raphael; Ropars, Virginie; Le Du, Marie-Helene; Maloisel, Laurent; Martini, Emmanuelle; Legrand, Pierre; Thureau, Aurelien; Cejka, Petr; Borde, Valerie; Charbonnier, Jean-Baptiste

Mechanism of MRX inhibition by Rif2 at telomeres

NATURE COMMUNICATIONS

IF15.7

2021-05-12

OAAI

Roisne-Hamelin, Florian; Pobiega, Sabrina; Jezequel, Kevin; Miron, Simona; Depagne, Jordane; Veaute, Xavier; Busso, Didier; Le Du, Marie-Helene; Callebaut, Isabelle; Charbonnier, Jean-Baptiste; Cuniasse, Philippe; Zinn-Justin, Sophie; Marcand, Stephane

Dynamics of Ku and bacterial non-homologous end-joining characterized using single DNA molecule analysis

NUCLEIC ACIDS RESEARCH

IF13.1

2021-02-15

OAAI

Oz, Robin; Wang, Jing L.; Guerois, Raphael; Goyal, Gaurav; Kk, Sriram; Ropars, Virginie; Sharma, Rajhans; Koca, Firat; Charbonnier, Jean-Baptiste; Modesti, Mauro; Strick, Terence R.; Westerlund, Fredrik

Modular Imaging Scaffold for Single-Particle Electron Microscopy 用于单颗粒电子显微镜的模块化成像支架

ACS NANO

IF16

2021-02-15

PREAI

Aissaoui, Nesrine; Lai-Kee-Him, Josephine; Mills, Allan; Declerck, Nathalie; Morichaud, Zakia; Brodolin, Konstantin; Baconnais, Sonia; Le Cam, Eric; Charbonnier, Jean Baptiste; Sounier, Remy; Granier, Sebastien; Ropars, Virginie; Bron, Patrick; Bellot, Gaetan

研究方向