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Robert W. Sobol

university of south alabama

58H指数
304论文数
1.2W被引数
收录论文 115
发表时间
Ubiquitylation of DNA polymerase β via atypical K27 chains signals a DNA damage responseDNA聚合酶β通过非典型K27链泛素化信号DNA损伤应答
err2026-04-13
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errOAAI
errQingming Fang; Christopher A Koczor; Wynand P Roos; Steve McClellan; Joel F Andrews; Robert W Sobol
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Uracil-DNA glycosylase deficiency is associated with repressed tumor cell-intrinsic inflammatory signaling and altered sensitivity to exogenous interferons尿嘧啶-DNA糖基酶缺乏与肿瘤细胞内源性炎性信号受抑及对外源性干扰素的敏感性改变相关。
err2025-12-01
err0
PREAI
errVendetti, Frank P.; Pandya, Pinakin; Sclafani, Carina R.; Pathak, Sudipta; Buj, Raquel; Jones, Reyna E.; Ivanov, Daniel; Aird, Katherine M.; Sobol, Robert W.; Bakkenist, Christopher J.
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Replication-associated base excision repair/single-strand break repair regulates PARG inhibitor response via the PRMT1/PRMT5/ATR axis复制相关的碱基切除修复/单链断裂修复通过PRMT1/PRMT5/ATR轴调节PARG抑制剂反应
err2025-12-01
err0
PREAI
errIbrahim, Md; Roos, Wynand P.; Schwartz, Jacob C.; Khan, Md Maruf; Al-Rahahleh, Rasha Q.; Beers, Libby A.; Pearson, Charlotte R.; Langham, Kahrie T.; Boyang, Louis; Clark, Jennifer; Hayat, Faisal; Fang, Qingming; Koczor, Christopher A.; Migaud, Marie E.; Sobol, Robert W.
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The pattern recognition receptors cGAS and IFI16 do not bind and initiate STING-dependent IFN-I signaling on dsDNA fragments containing deoxy-uracil
err2025-11-01
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PREAI
errPandya, Pinakin; Vendetti, Frank P.; Pathak, Sudipta; Zhang, Yunqi; Deppas, Joshua J.; Jones, Reyna; Buj-Gomez, Raquel; Aird, Katherine M.; Beumer, Jan H.; Sobol, Robert W.; Bakkenist, Christopher J.
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Exploiting metabolic vulnerabilities to improve cancer therapeutics利用代谢脆弱性改善癌症治疗
err2025-08-28
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PREAI
errIbrahim H. Ibrahim; Cheng-Han Lin; Ming Zhou; Jer-Yen Yang; Robert W. Sobol; Ming Tan
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TRIP12's role in the governance of DNA polymerase β involvement in DNA damage response and repairTRIP12在DNA聚合酶β参与DNA损伤应答和修复的治理中的作用
err2025-07-08
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errOAAI
errInanc, Burcu; Fang, Qingming; Roos, Wynand P.; Andrews, Joel F.; Zeng, Xuemei; Clark, Jennifer; Li, Jianfeng; Dey, Nupur B.; Ibrahim, Md; Sykora, Peter; Yu, Zhongxun; Pearson, Charlotte R.; Braganza, Andrea; Verheij, Marcel; Jonkers, Jos; Yates, Nathan A.; Vens, Conchita; Sobol, Robert W.
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C-terminal residues of DNA polymerase β and E3 ligase required for ubiquitin-linked proteolysis of oxidative DNA-protein crosslinks
err2024-11-01
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errOAAI
errQuinones, Jason L.; Tang, Meiyi; Fang, Qingming; Sobol, Robert W.; Demple, Bruce
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Protein lipoylation: mitochondria, cuproptosis, and beyond
err2024-08-01
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PREAI
errLin, Cheng-Han; Chin, Yeh; Zhou, Ming; Sobol, Robert W.; Hung, Mien-Chie; Tan, Ming
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Oncometabolite 2-hydroxyglutarate suppresses basal protein levels of DNA polymerase beta that enhances alkylating agent and PARG inhibition induced cytotoxicity
err2024-08-01
err1
errOAAI
errSaville, Kate M.; Al-Rahahleh, Rasha Q.; Siddiqui, Aisha H.; Andrews, Morgan E.; Koczor, Christopher A.; Roos, Wynand P.; Andrews, Joel F.; Hayat, Faisal; Migaud, Marie E.; Sobol, Robert W.
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CHK1 inhibitor induced PARylation by targeting PARG causes excessive replication and metabolic stress and overcomes chemoresistance in ovarian cancer
err2024-06-11
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errOAAI
errAcharya, Ganesh; Mani, Chinnadurai; Sah, Naresh; Saamarthy, Karunakar; Young, Robert; Reedy, Mark B.; Sobol, Robert W.; Palle, Komaraiah
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Regulation of replication-induced PARP1/PARP2 activation by base excision repair: Implications for PARP and PARG inhibitor resistance
err2024-06-10
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PREAI
errIbrahim, Md; Khan, Md Maruf; Roos, Wynand P.; Al-Rahaleh, Rasha Q.; Hayat, Faisal; Migaud, Marie E.; Sobol, Robert W.
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CometChip enables parallel analysis of multiple DNA repair activities (vol 106, 103176, 2021)
err2024-06-01
err1
PREAI
errGe, Jing; Ngo, Le P.; Kaushal, Simran; Tay, Ian J.; Thadhani, Elina; Kay, Jennifer E.; Mazzucato, Patrizia; Chow, Danielle; Fessler, Jessica; Weingeist, David M.; Sobol, Robert W.; Samson, Leona D.; Floyd, Scott R.; Engelward, Bevin P.
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Base excision repair regulation of replication stress induced poly(ADP-ribose) checkpoints
err2024-03-22
err0
PREAI
errIbrahim, Md; Khan, Md Maruf; Al-Rahaleh, Rasha Q.; Clark, Jennifer; Hayat, Faisal; Fang, Qingming; Koczor, Christopher A.; Migaud, Marie E.; Sobol, Robert W.
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DNA polymerase beta expression in head & neck cancer modulates the poly-ADP-ribose-mediated replication checkpoint
err2024-03-22
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PREAI
errKhan, Md Maruf; Angajala, Anusha; Gibbs, Denise Y.; Liu, Jeffrey C.; Ragin, Camille; Sobol, Robert W.
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Tumor Treating Fields (TTFields) show efficacy in Triple-Negative breast cancer (TNBC) cells alone and in combination with PARP inhibitor Talazoparib
err2024-03-22
err0
PREAI
errGhandali, Maryam; Srinivasan, Praveen; Xia, Yutong; Wong, Eric T.; Sobol, Robert W.; Zhou, Lanlan; Carneiro, Benedito A.; Graff, Stephanie L.; El-Deiry, Wafik S.
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Uracil DNA glycosylase activity limits deoxyuridine contamination in genomic DNA and is essential for the type-1 interferon response in cells treated with ATR kinase inhibitors
err2024-01-09
err0
PREAI
errPandya, Pinakin; Vendetti, Frank P.; Ghoubaira, Joseph A.; Pathak, Sudipta; Deppas, Joshua J.; Jones, Reyna E.; Zhang, Yunqi; Ivanov, Daniel; Buj, Raquel; Aird, Katherine M.; Beumer, Jan H.; Sobol, Robert W.; Bakkenist, Christopher J.
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