Robert W. Sobol - Publications, H-index & Citations

Robert W. Sobol

university of south alabama

58H指数

304论文数

1.2W被引数

收录论文 115

发表时间

Ubiquitylation of DNA polymerase β via atypical K27 chains signals a DNA damage response DNA聚合酶β通过非典型K27链泛素化信号DNA损伤应答

Nucleic Acids Research

IF13.1

2026-04-13

OAAI

Qingming Fang; Christopher A Koczor; Wynand P Roos; Steve McClellan; Joel F Andrews; Robert W Sobol

Synergistic Cellular Toxicity from Inhibition of Poly(ADP-ribose) Glycohydrolase (PARG) and Ubiquitin-Specific Protease 1 (USP1)聚(ADP-核糖)糖基水解酶(PARG)和泛素特异性蛋白酶1(USP1)抑制的协同细胞毒性

Toxics

IF4.1

2026-02-10

OAAI

Stefan M. Leonard; Charlotte R. Pearson; Wynand P. Roos; Robert W. Sobol

DNA Repair Special Issue: Genome maintenance pathways in cancer - etiology, biomarkers and targets

DNA Repair

IF2.7

2026-01-29

PREAI

Robert W. Sobol; Gianluca Tell

Uracil-DNA glycosylase deficiency is associated with repressed tumor cell-intrinsic inflammatory signaling and altered sensitivity to exogenous interferons 尿嘧啶-DNA糖基酶缺乏与肿瘤细胞内源性炎性信号受抑及对外源性干扰素的敏感性改变相关。

NAR CANCER

IF3.2

2025-12-01

PREAI

Vendetti, Frank P.; Pandya, Pinakin; Sclafani, Carina R.; Pathak, Sudipta; Buj, Raquel; Jones, Reyna E.; Ivanov, Daniel; Aird, Katherine M.; Sobol, Robert W.; Bakkenist, Christopher J.

Replication-associated base excision repair/single-strand break repair regulates PARG inhibitor response via the PRMT1/PRMT5/ATR axis 复制相关的碱基切除修复/单链断裂修复通过PRMT1/PRMT5/ATR轴调节PARG抑制剂反应

NAR CANCER

IF3.2

2025-12-01

PREAI

Ibrahim, Md; Roos, Wynand P.; Schwartz, Jacob C.; Khan, Md Maruf; Al-Rahahleh, Rasha Q.; Beers, Libby A.; Pearson, Charlotte R.; Langham, Kahrie T.; Boyang, Louis; Clark, Jennifer; Hayat, Faisal; Fang, Qingming; Koczor, Christopher A.; Migaud, Marie E.; Sobol, Robert W.

Climate concerns for clinicians: evaluating harmful algal bloom knowledge and educational opportunities for health care provider students 临床医生对气候变化的担忧：评估医疗保健提供者学生对有害藻华知识的了解及教育机会

Frontiers in Medicine

IF3

2025-11-04

OAAI

Alexander Lund; Carrie McNair; Chelsea McGowen; Janel Lowman; Robert Sobol; Michael Parsons; Jennifer Pierce

The pattern recognition receptors cGAS and IFI16 do not bind and initiate STING-dependent IFN-I signaling on dsDNA fragments containing deoxy-uracil

JOURNAL OF IMMUNOLOGY

IF3.4

2025-11-01

PREAI

Pandya, Pinakin; Vendetti, Frank P.; Pathak, Sudipta; Zhang, Yunqi; Deppas, Joshua J.; Jones, Reyna; Buj-Gomez, Raquel; Aird, Katherine M.; Beumer, Jan H.; Sobol, Robert W.; Bakkenist, Christopher J.

Exploiting metabolic vulnerabilities to improve cancer therapeutics 利用代谢脆弱性改善癌症治疗

trends in endocrinology and metabolism

IF0

2025-08-28

PREAI

Ibrahim H. Ibrahim; Cheng-Han Lin; Ming Zhou; Jer-Yen Yang; Robert W. Sobol; Ming Tan

TRIP12's role in the governance of DNA polymerase β involvement in DNA damage response and repair TRIP12在DNA聚合酶β参与DNA损伤应答和修复的治理中的作用

NUCLEIC ACIDS RESEARCH

IF13.1

2025-07-08

OAAI

Inanc, Burcu; Fang, Qingming; Roos, Wynand P.; Andrews, Joel F.; Zeng, Xuemei; Clark, Jennifer; Li, Jianfeng; Dey, Nupur B.; Ibrahim, Md; Sykora, Peter; Yu, Zhongxun; Pearson, Charlotte R.; Braganza, Andrea; Verheij, Marcel; Jonkers, Jos; Yates, Nathan A.; Vens, Conchita; Sobol, Robert W.

C-terminal residues of DNA polymerase β and E3 ligase required for ubiquitin-linked proteolysis of oxidative DNA-protein crosslinks

DNA REPAIR

IF2.7

2024-11-01

OAAI

Quinones, Jason L.; Tang, Meiyi; Fang, Qingming; Sobol, Robert W.; Demple, Bruce

Metastatic hormone receptor-positive breast cancer outcomes in 628 patients with BRCA1, BRCA2, or PALB2 pathogenic variants: Real-world data analysis of genomics and targeted therapy sequencing 携带BRCA1、BRCA2或PALB2致病性变异的628例转移性激素受体阳性乳腺癌患者的结局：基因组学和靶向治疗序贯方案的真实世界数据分析

ANNALS OF ONCOLOGY

IF65.4

2024-09-01

PREAI

Parkinson, G.; Lustberg, M.; Nazari, S.; Elliott, A.; Sledge, G.; Jeselsohn, R.; Hsu, E.; Sobol, R. W.; Sandoval-Leon, A.; Gopalakrishnan, R.; Makhoul, I.; Nye, L. E.; Kurian, A.; Lynce, F.; Graff, S.

Protein lipoylation: mitochondria, cuproptosis, and beyond

TRENDS IN BIOCHEMICAL SCIENCES

IF11

2024-08-01

PREAI

Lin, Cheng-Han; Chin, Yeh; Zhou, Ming; Sobol, Robert W.; Hung, Mien-Chie; Tan, Ming

Oncometabolite 2-hydroxyglutarate suppresses basal protein levels of DNA polymerase beta that enhances alkylating agent and PARG inhibition induced cytotoxicity

DNA REPAIR

IF2.7

2024-08-01

OAAI

Saville, Kate M.; Al-Rahahleh, Rasha Q.; Siddiqui, Aisha H.; Andrews, Morgan E.; Koczor, Christopher A.; Roos, Wynand P.; Andrews, Joel F.; Hayat, Faisal; Migaud, Marie E.; Sobol, Robert W.

CHK1 inhibitor induced PARylation by targeting PARG causes excessive replication and metabolic stress and overcomes chemoresistance in ovarian cancer

CELL DEATH DISCOVERY

IF7

2024-06-11

OAAI

Acharya, Ganesh; Mani, Chinnadurai; Sah, Naresh; Saamarthy, Karunakar; Young, Robert; Reedy, Mark B.; Sobol, Robert W.; Palle, Komaraiah

Regulation of replication-induced PARP1/PARP2 activation by base excision repair: Implications for PARP and PARG inhibitor resistance

MOLECULAR CANCER THERAPEUTICS

IF5.5

2024-06-10

PREAI

Ibrahim, Md; Khan, Md Maruf; Roos, Wynand P.; Al-Rahaleh, Rasha Q.; Hayat, Faisal; Migaud, Marie E.; Sobol, Robert W.

CometChip enables parallel analysis of multiple DNA repair activities (vol 106, 103176, 2021)

DNA REPAIR

IF2.7

2024-06-01

PREAI

Ge, Jing; Ngo, Le P.; Kaushal, Simran; Tay, Ian J.; Thadhani, Elina; Kay, Jennifer E.; Mazzucato, Patrizia; Chow, Danielle; Fessler, Jessica; Weingeist, David M.; Sobol, Robert W.; Samson, Leona D.; Floyd, Scott R.; Engelward, Bevin P.

Base excision repair regulation of replication stress induced poly(ADP-ribose) checkpoints

CANCER RESEARCH

IF16.6

2024-03-22

PREAI

Ibrahim, Md; Khan, Md Maruf; Al-Rahaleh, Rasha Q.; Clark, Jennifer; Hayat, Faisal; Fang, Qingming; Koczor, Christopher A.; Migaud, Marie E.; Sobol, Robert W.

DNA polymerase beta expression in head & neck cancer modulates the poly-ADP-ribose-mediated replication checkpoint

CANCER RESEARCH

IF16.6

2024-03-22

PREAI

Khan, Md Maruf; Angajala, Anusha; Gibbs, Denise Y.; Liu, Jeffrey C.; Ragin, Camille; Sobol, Robert W.

Tumor Treating Fields (TTFields) show efficacy in Triple-Negative breast cancer (TNBC) cells alone and in combination with PARP inhibitor Talazoparib

CANCER RESEARCH

IF16.6

2024-03-22

PREAI

Ghandali, Maryam; Srinivasan, Praveen; Xia, Yutong; Wong, Eric T.; Sobol, Robert W.; Zhou, Lanlan; Carneiro, Benedito A.; Graff, Stephanie L.; El-Deiry, Wafik S.

Uracil DNA glycosylase activity limits deoxyuridine contamination in genomic DNA and is essential for the type-1 interferon response in cells treated with ATR kinase inhibitors

CANCER RESEARCH

IF16.6

2024-01-09

PREAI

Pandya, Pinakin; Vendetti, Frank P.; Ghoubaira, Joseph A.; Pathak, Sudipta; Deppas, Joshua J.; Jones, Reyna E.; Zhang, Yunqi; Ivanov, Daniel; Buj, Raquel; Aird, Katherine M.; Beumer, Jan H.; Sobol, Robert W.; Bakkenist, Christopher J.

研究方向