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M

Mischa Machius

university of texas medical branch

50H指数
177论文数
8.2K被引数
收录论文 46
发表时间
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Efficient In Vivo Pharmacological Inhibition of ΔFOSB; an AP-1 Transcription Factor; in the Brain高效体内药理学抑制ΔFOSB；一种AP-1转录因子；在大脑中
errACS Chemical Neuroscience
IF3.9
err2026-03-12
err0
PREAI
errSean McNeme; Anil Kumar; Yun Young Yim; Brandon W. Hughes; Corey St. Romain; Yi Li; Ashwani Kumar; Qichao Bao; Molly Estill; Shanghua Fan; Nadeen Takatka; Earnest P. Chen; Matthew Rivera; Haiying Chen; Alfred J. Robison; Mischa Machius; Stephen J. Haggarty; Jeannie Chin; Eric J. Nestler; Jia Zhou; Gabby Rudenko
err分享
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Editorial Expression of Concern: Munc13 C2B domain is an activity-dependent Ca2+ regulator of synaptic exocytosis编辑关注声明：Munc13 C2B结构域是活动依赖的Ca2+调节剂，可调控突触胞吐作用
errNature Structural & Molecular Biology
IF10.1
err2025-12-03
err0
errOAAI
errOk-Ho Shin; Jun Lu; Jeong-Seop Rhee; Diana R. Tomchick; Zhiping P. Pang; Sonja M. Wojcik; Marcial Camacho-Perez; Nils Brose; Mischa Machius; Josep Rizo; Christian Rosenmund; Thomas C. Südhof
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err收藏
Designer molecules of the synaptic organizer MDGA1 reveal 3D conformational control of biological function突触组织者MDGA1的设计分子揭示了生物功能的3D构象控制
errJOURNAL OF BIOLOGICAL CHEMISTRY
IF3.9
err2023-04-01
err5
errOAAI
errLee, Hubert; Chofflet, Nicolas; Liu, Jianfang; Fan, Shanghua; Lu, Zhuoyang; Rojas, Martin Resua; Penndorf, Patrick; Bailey, Aaron O.; Russell, William K.; Machius, Mischa; Ren, Gang; Takahashi, Hideto; Rudenko, Gabby
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err收藏
Chemically targeting the redox switch in AP1 transcription factor ΔFOSB
errNUCLEIC ACIDS RESEARCH
IF13.1
err2022-08-30
err3
errOAAI
errKumar, Ashwani; Aglyamova, Galina; Yim, Yun Young; Bailey, Aaron O.; Lynch, Haley M.; Powell, Reid T.; Nguyen, Nghi D.; Rosenthal, Zachary; Zhao, Wen-Ning; Li, Yi; Chen, Jianping; Fan, Shanghua; Lee, Hubert; Russell, William K.; Stephan, Clifford; Robison, Alfred J.; Haggarty, Stephen J.; Nestler, Eric J.; Zhou, Jia; Machius, Mischa; Rudenko, Gabby
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Activator Protein-1: redox switch controlling structure and DNA-binding
errNUCLEIC ACIDS RESEARCH
IF13.1
err2017-09-07
err48
errOAAI
errYin, Zhou; Machius, Mischa; Nestler, Eric J.; Rudenko, Gabby
err分享
err收藏
Molecular Mechanism of MDGA1: Regulation of Neuroligin 2:Neurexin Trans-synaptic Bridges
errNEURON
IF15
err2017-06-01
err60
errOAAI
errGangwar, Shanti Pal; Zhong, Xiaoying; Seshadrinathan, Suchithra; Chen, Hui; Machius, Mischa; Rudenko, Gabby
err分享
err收藏
TIR-only protein RBA1 recognizes a pathogen effector to regulate cell death in Arabidopsis
errPROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
IF9.1
err2017-01-30
err133
errOAAI
errNishimura, Marc T.; Anderson, Ryan G.; Cherkis, Karen A.; Law, Terry F.; Liu, Qingli L.; Machius, Mischa; Nimchuk, Zachary L.; Yang, Li; Chung, Eui-Hwan; El Kasmi, Farid; Hyunh, Michael; Nishimura, Erin Osborne; Sondek, John E.; Dangl, Jeffery L.
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Discovery of Macrocyclic Pyrimidines as MerTK-Specific Inhibitors大环嘧啶作为MerTK特异性抑制剂的发现
errCHEMMEDCHEM
IF3.4
err2017-01-09
err29
errOAAI
errMcIver, Andrew L.; Zhang, Weihe; Liu, Qingyang; Jiang, Xinpeng; Stashko, Michael A.; Nichols, James; Miley, Michael J.; Norris-Drouin, Jacqueline; Machius, Mischa; DeRyckere, Deborah; Wood, Edgar; Graham, Douglas K.; Earp, H. Shelton; Kireev, Dmitri; Frye, Stephen V.; Wang, Xiaodong
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Design and Synthesis of Novel Macrocyclic Mer Tyrosine Kinase Inhibitors
errACS MEDICINAL CHEMISTRY LETTERS
IF4
err2016-09-21
err28
errOAAI
errWang, Xiaodong; Liu, Jing; Zhang, Weihe; Stashko, Michael A.; Nichols, James; Miley, Michael J.; Norris-Drouin, Jacqueline; Chen, Zhilong; Machius, Mischa; DeRyckere, Deborah; Wood, Edgar; Graham, Douglas K.; Earp, H. Shelton; Kireev, Dmitri; Frye, Stephen V.
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err收藏
Functional analysis of rare variants found in schizophrenia implicates a critical role for GIT1-PAK3 signaling in neuroplasticity
errMOLECULAR PSYCHIATRY
IF10.1
err2016-07-26
err31
errOAAI
errKim, M. J.; Biag, J.; Fass, D. M.; Lewis, M. C.; Zhang, Q.; Fleishman, M.; Gangwar, S. P.; Machius, M.; Fromer, M.; Purcell, S. M.; McCarroll, S. A.; Rudenko, G.; Premont, R. T.; Scolnick, E. M.; Haggarty, S. J.
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err收藏
Structural analyses to identify selective inhibitors of glyceraldehyde 3-phosphate dehydrogenase-S, a sperm-specific glycolytic enzyme
errMOLECULAR HUMAN REPRODUCTION
IF3.5
err2016-02-26
err24
errOAAI
errDanshina, Polina V.; Qu, Weidong; Temple, Brenda R.; Rojas, Rafael J.; Miley, Michael J.; Machius, Mischa; Betts, Laurie; O'Brien, Deborah A.
err分享
err收藏
Pseudo-Cyclization through Intramolecular Hydrogen Bond Enables Discovery of Pyridine Substituted Pyrimidines as New Mer Kinase Inhibitors (vol 56, pg 9683, 2013)
errJOURNAL OF MEDICINAL CHEMISTRY
IF6.8
err2014-08-18
err0
PREAI
errZhang, Weihe; Zhang, Dehui; Stashko, Michael A.; DeRyckere, Deborah; Hunter, Debra; Kireev, Dmitri; Miley, Michael J.; Cummings, Christopher; Lee, Minjung; Norris-Drouin, Jacqueline; Stewart, Wendy M.; Sather, Susan; Zhou, Yingqiu; Kirkpatrick, Gregory; Machius, Mischa; Janzen, William P.; Earp, H. Shelton; Graham, Douglas K.; Frye, Stephen V.; Wang, Xiaodong
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err收藏
Discovery of Mer Specific Tyrosine Kinase Inhibitors for the Treatment and Prevention of Thrombosis (vol 56, pg 9693, 2013)
errJOURNAL OF MEDICINAL CHEMISTRY
IF6.8
err2014-08-18
err0
errOAAI
errZhang, Weihe; McIver, Andrew L.; Stashko, Michael A.; DeRyckere, Deborah; Branchford, Brian R.; Hunter, Debra; Kireev, Dmitri; Miley, Michael J.; Norris-Drouin, Jacqueline; Stewart, Wendy M.; Lee, Minjung; Sather, Susan; Zhou, Yingqiu; Di Paola, Jorge A.; Machius, Mischa; Janzen, William P.; Earp, H. Shelton; Graham, Douglas K.; Frye, Stephen V.; Wang, Xiaodong
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Discovery of Small Molecule Mer Kinase Inhibitors for the Treatment of Pediatric Acute Lymphoblastic Leukemia (vol 3, pg 129, 2012)
errACS MEDICINAL CHEMISTRY LETTERS
IF4
err2014-08-15
err0
errOAAI
errLiu, Jing; Yang, Chao; Simpson, Catherine; DeRyckere, Deborah; Van Deusen, Amy; Miley, Michael J.; Kireev, Dmitri; Norris-Drouin, Jacqueline; Sather, Susan; Hunter, Debra; Korboukh, Victoria K.; Patel, Hari S.; Janzen, William P.; Machius, Mischa; Johnson, Gary L.; Earp, H. Shelton; Graham, Douglas K.; Frye, Stephen V.; Wang, Xiaodong
err分享
err收藏
Pseudo-Cyclization through Intramolecular Hydrogen Bond Enables Discovery of Pyridine Substituted Pyrimidines as New Mer Kinase Inhibitors
errJOURNAL OF MEDICINAL CHEMISTRY
IF6.8
err2013-11-20
err71
errOAAI
errZhang, Weihe; Zhang, Dehui; Stashko, Michael A.; DeRyckere, Deborah; Hunter, Debra; Kireev, Dmitri; Miley, Michael J.; Cummings, Christopher; Lee, Minjung; Norris-Drouin, Jacqueline; Stewart, Wendy M.; Sather, Susan; Zhou, Yingqiu; Kirkpatrick, Gregory; Machius, Mischa; Janzen, William P.; Earp, H. Shelton; Graham, Douglas K.; Frye, Stephen V.; Wang, Xiaodong
err分享
err收藏
Discovery of Mer Specific Tyrosine Kinase Inhibitors for the Treatment and Prevention of Thrombosis
errJOURNAL OF MEDICINAL CHEMISTRY
IF6.8
err2013-11-20
err59
errOAAI
errZhang, Weihe; McIver, Andrew L.; Stashko, Michael A.; DeRyckere, Deborah; Branchford, Brian R.; Hunter, Debra; Kireev, Dmitri; Miley, Michael J.; Norris-Drouin, Jacqueline; Stewart, Wendy M.; Lee, Minjung; Sather, Susan; Zhou, Yingqiu; Di Paola, Jorge A.; Machius, Mischa; Janzen, William P.; Earp, H. Shelton; Graham, Douglas K.; Frye, Stephen V.; Wang, Xiaodong
err分享
err收藏
Heterotrimeric G-protein Signaling Is Critical to Pathogenic Processes in Entamoeba histolytica
errPLOS PATHOGENS
IF4.9
err2012-11-15
err23
errOAAI
errBosch, Dustin E.; Kimple, Adam J.; Muller, Robin E.; Giguere, Patrick M.; Machius, Mischa; Willard, Francis S.; Temple, Brenda R. S.; Siderovski, David P.
err分享
err收藏
Discovery of Small Molecule Mer Kinase Inhibitors for the Treatment of Pediatric Acute Lymphoblastic Leukemia
errACS MEDICINAL CHEMISTRY LETTERS
IF4
err2012-01-13
err111
errOAAI
errLiu, Jing; Yang, Chao; Simpson, Catherine; DeRyckere, Deborah; Van Deusen, Amy; Miley, Michael J.; Kireev, Dmitri; Norris-Drouin, Jacqueline; Sather, Susan; Hunter, Debra; Korboukh, Victoria K.; Patel, Hari S.; Janzen, William P.; Machius, Mischa; Johnson, Gary L.; Earp, H. Shelton; Graham, Douglas K.; Frye, Stephen V.; Wang, Xiaodong
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err收藏
Metal-Mediated Affinity and Orientation Specificity in a Computationally Designed Protein Homodimer
errJOURNAL OF THE AMERICAN CHEMICAL SOCIETY
IF15.6
err2011-12-15
err116
errOAAI
errDer, Bryan S.; Machius, Mischa; Miley, Michael J.; Mills, Jeffrey L.; Szyperski, Thomas; Kuhlman, Brian
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err收藏
Computational design of a symmetric homodimer using β-strand assembly
errPROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
IF9.1
err2011-12-05
err90
errOAAI
errStranges, P. Benjamin; Machius, Mischa; Miley, Michael J.; Tripathy, Ashutosh; Kuhlman, Brian
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err收藏

研究方向

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合作学者
合作期刊
T
Thomas C. Südhof
H 指数: 192 · 论文数: 753
E
Eric J. Nestler
H 指数: 187 · 论文数: 1.7K
R
Robert Huber
H 指数: 147 · 论文数: 746
S
Steven A. McCarroll
H 指数: 131 · 论文数: 405
J
Jeffery L. Dangl
H 指数: 126 · 论文数: 358
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