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肖

肖武汉 (Wuhan Xiao)

hubei hongshan laboratory

H指数:34

被引数:9,223

个人简介

任职于中国科学院水生生物研究所，任研究员。1989年毕业于武汉大学，获学士学位；1997年在中国科学院水生生物研究所获博士学位。1994年至1998年任助理研究员；1998年10月至2003年10月在美国西北大学做博士后，任研究助理；2003年10月至2005年12月任研究助理教授；2006年8月至10月在美国匹兹堡大学任研究顾问。

教育背景

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工作经历

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荣誉奖项

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cGAS attenuates hypoxia-inducible factor signaling via chaperone-mediated autophagic degradation of HIFα

cGAS通过伴侣介导的自噬降解HIFα来减弱缺氧诱导因子信号通路

IF6.9

2026-05-220

OAAI

IRF3 attenuates hypoxia signaling by retaining HIF-α in the cytoplasm

IRF3通过将hif-α 保留在细胞质中而减弱缺氧信号传导

IF6.9

2026-01-100

OAAI

Grass carp (Ctenopharyngodon idella) SMYD3 negatively regulates antiviral innate immunity by methylating IRF3 and IRF7 during GCRV infection

草鱼(Ctenopharyngodon idella)的SMYD3通过甲基化IRF3和IRF7，在GCRV感染期间负向调控抗病毒先天免疫。

JOURNAL OF IMMUNOLOGY

IF3.4

2025-11-010

PRE

MYLIP attenuates hypoxia tolerance by inducing K27-linked polyubiquitination and subsequent proteasomal degradation of HIF-α

MYLIP通过诱导K27连接的多泛素化以及随后的HIF-α蛋白酶体降解来减弱缺氧耐受性。

COMMUNICATIONS BIOLOGY

IF5.1

2025-05-210

OA

Zebrafish fkbp5 attenuates antiviral innate immunity by autophagic degradation of transcription factor irf7

斑马鱼fkbp5通过自噬降解转录因子irf7来减弱抗病毒先天免疫。

JOURNAL OF IMMUNOLOGY

IF3.4

2025-05-200

PRE

Spring viremia of carp virus infection induces hypoxia response in zebrafish by stabilizing hif1α

JOURNAL OF VIROLOGY

IF3.8

2025-01-310

OAAI

Genetic evidence for the suppressive role of zebrafish vhl targeting mavs in antiviral innate immunity during RNA virus infection

JOURNAL OF IMMUNOLOGY

IF3.4

2025-01-230

PRE

Zebrafish phd1 enhances mavs-mediated antiviral responses in a hydroxylation-independent manner

JOURNAL OF VIROLOGY

IF3.8

2024-09-170

PRE

Zebrafish mylipb attenuates antiviral innate immunity through two synergistic mechanisms targeting transcription factor irf3

IF4.9

2024-05-130

OAAI

Oxygen enhances antiviral innate immunity through maintenance of EGLN1-catalyzed proline hydroxylation of IRF3

NATURE COMMUNICATIONS

IF15.7

2024-04-261

OAAI

Dual modifying of MAVS at lysine 7 by SIRT3-catalyzed deacetylation and SIRT5catalyzed desuccinylation orchestrates antiviral innate immunity

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2024-04-183

PRE

New insights into the all-testis differentiation in zebrafish with compromised endogenous androgen and estrogen synthesis

IF3.7

2024-03-072

OAAI

Factor inhibiting HIF negatively regulates antiviral innate immunity via hydroxylation of IKK

IF6.9

2024-01-012

OA

Asymmetric arginine dimethylation of cytosolic RNA and DNA sensors by PRMT3 attenuates antiviral innate immunity

PRMT3对胞质RNA和DNA传感器的不对称精氨酸二甲基化减弱了抗病毒先天免疫

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2023-08-287

OAAI

ELL targets c-Myc for proteasomal degradation and suppresses tumour growth (vol 7, 11057, 2016)

NATURE COMMUNICATIONS

IF15.7

2023-05-230

OAAI

SET7 methylates the deubiquitinase OTUB1 at Lys 122 to impair its binding to E2 enzyme UBC13 and relieve its suppressive role on ferroptosis

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2023-04-018

OAAI

ELL Inhibits E2F1 Transcriptional Activity by Enhancing E2F1 Deacetylation via Recruitment of Histone Deacetylase 1

MOLECULAR AND CELLULAR BIOLOGY

IF2.7

2023-03-2012

OA

EAF2 Suppresses Hypoxia-Induced Factor 1 α Transcriptional Activity by Disrupting Its Interaction with Coactivator CBP/p300

MOLECULAR AND CELLULAR BIOLOGY

IF2.7

2023-03-2045

OA

Zebrafish maoc1 Attenuates Spring Viremia of Carp Virus Propagation by Promoting Autophagy-Lysosome-Dependent Degradation of Viral Phosphoprotein

JOURNAL OF VIROLOGY

IF3.8

2023-02-287

OA

Methyltransferase SMYD3 impairs hypoxia tolerance by augmenting hypoxia signaling independent of its enzymatic activity

甲基转移酶SMYD3通过独立于其酶活性增加缺氧信号来损害缺氧耐受性

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2022-12-019

OAAI