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Bile acid regulation of C/EBPβ, CREB, and c-Jun function, via the extracellular signal-regulated kinase and c-Jun NH2-terminal kinase pathways, modulates the apoptotic response of hepatocytes Qiao, L; Han, SI; Fang, YW; Park, JS; Gupta, S; Gilfor, D; Amorino, G; Valerie, K; Sealy, L; Engelhardt, JF; Grant, S; Hylemon, PB; Dent, P 分享 收藏
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Lymph node-targeting adjuvant/neoantigen-codelivering vaccines for combination glioblastoma radioimmunotherapy Su, Ting; Zhou, Shurong; Yang, Suling; Humble, Nicholas; Zhang, Fuwu; Yu, Guocan; Bos, Paula D.; Cheng, Furong; Valerie, Kristoffer; Zhu, Guizhi 分享 收藏
ATM phosphorylates PP2A subunit A resulting in nuclear export and spatiotemporal regulation of the DNA damage response Sule, Amrita; Golding, Sarah E.; Ahmad, Syed F.; Watson, James; Ahmed, Mostafa H.; Kellogg, Glen E.; Bernas, Tytus; Koebley, Sean; Reed, Jason C.; Povirk, Lawrence F.; Valerie, Kristoffer 分享 收藏
PEAMOtecan, a novel chronotherapeutic polymeric drug for brain cancer Allen, Jasmine; Wang, Juan; Zolotarskaya, Olga Yu; Sule, Amrita; Mohammad, Sajjad; Arslan, Shukaib; Wynne, Kenneth J.; Yang, Hu; Valerie, Kristoffer 分享 收藏
mda-9/Syntenin: A Positive Regulator of Melanoma Metastasis (Expression of Concern of Vol 65, Pg 10901, 2005) Boukerche, Habib; Su, Zao-Zhong; Emdad, Luni; Baril, Patrick; Balme, Brigitte; Thomas, Luc; Randolph, Aaron; Valerie, Kristoffer; Sarkar, Devanand; Fisher, Paul B. 分享 收藏
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Orally Bioavailable and Blood-Brain Barrier-Penetrating ATM Inhibitor (AZ32) Radiosensitizes Intracranial Gliomas in Mice Karlin, Jeremy; Allen, Jasmine; Ahmad, Syed F.; Hughes, Gareth; Sheridan, Victoria; Odedra, Rajesh; Farrington, Paul; Cadogan, Elaine B.; Riches, Lucy C.; Garcia-Trinidad, Antonio; Thomason, Andrew G.; Patel, Bhavika; Vincent, Jennifer; Lau, Alan; Pike, Kurt G.; Hunt, Thomas A.; Sule, Amrita; Valerie, Nicholas C. K.; Biddlestone-Thorpe, Laura; Kahn, Jenna; Beckta, Jason M.; Mukhopadhyay, Nitai; Barlaam, Bernard; Degorce, Sebastien L.; Kettle, Jason; Colclough, Nicola; Wilson, Joanne; Smith, Aaron; Barrett, Ian P.; Zheng, Li; Zhang, Tianwei; Wang, Yingchun; Chen, Kan; Pass, Martin; Durant, Stephen T.; Valerie, Kristoffer 分享 收藏
The brain-penetrant clinical ATM inhibitor AZD1390 radiosensitizes and improves survival of preclinical brain tumor models Durant, Stephen T.; Zheng, Li; Wang, Yingchun; Chen, Kan; Zhang, Lingli; Zhang, Tianwei; Yang, Zhenfan; Riches, Lucy; Trinidad, Antonio G.; Fok, Jacqueline H. L.; Hunt, Tom; Pike, Kurt G.; Wilson, Joanne; Smith, Aaron; Colclough, Nicola; Reddy, Venkatesh Pilla; Sykes, Andrew; Janefeldt, Annika; Johnstrom, Peter; Varnas, Katarina; Takano, Akihiro; Ling, Stephanie; Orme, Jonathan; Stott, Jonathan; Roberts, Caroline; Barrett, Ian; Jones, Gemma; Roudier, Martine; Pierce, Andrew; Allen, Jasmine; Kahn, Jenna; Sule, Amrita; Karlin, Jeremy; Cronin, Anna; Chapman, Melissa; Valerie, Kristoffer; Illingworth, Ruth; Pass, Martin 分享 收藏
AZD1390, a potent and selective orally bioavailable blood-brain barrier-penetrant ATM inhibitor, radiosensitizes and improves survival of orthotopic glioma and metastatic brain tumor models Durant, Steve T.; Pike, Kurt G.; Colclough, Nicola; Riches, Lucy; Garcia-Trinidad, Antonio; Hunt, Thomas; Ling, Stephanie; Stott, Jonathan; Barrett, Ian; Zheng, Li; Wang, Yingchun; Chen, Kan; Zhang, Tianwei; Reddy, Venkatesh Pilla; Sykes, Andrew; Johnstrom, Peter; Jones, Gemma; Pierce, Andrew; Karlin, Jeremy; Kahn, Jenna; Allen, Jasmine; Valerie, Kristoffer; Illingworth, Ruth; Pass, Martin 分享 收藏
Next-Generation ATM Kinase Inhibitors Under Development Radiosensitize Glioblastoma With Conformal Radiation in a Mouse Orthotopic Model Kahn, J.; Allen, J.; Karlin, J. D.; Ahmad, S.; Sule, A.; Tokarz, M.; Henderson, A.; Mukhopadhyay, N. D.; Pike, K.; Colclough, N.; Pass, M.; Durant, S.; Valerie, K. 分享 收藏
Inhibition of radiation-induced glioblastoma invasion by genetic and pharmacological targeting of MDA-9/Syntenin Kegelman, Timothy P.; Wu, Bainan; Das, Swadesh K.; Talukdar, Sarmistha; Beckta, Jason M.; Hu, Bin; Emdad, Luni; Valerie, Kristoffer; Sarkar, Devanand; Furnari, Frank B.; Cavenee, Webster K.; Wei, Jun; Purves, Angela; De, Surya K.; Pellecchia, Maurizio; Fisher, Paul B. 分享 收藏
Blood-brain barrier penetrating ATM inhibitor (AZ32) radiosensitises intracranial gliomas in mice Durant, Steve T.; Karlin, Jeremy; Pike, Kurt; Colclough, Nicola; Mukhopadhyay, N.; Ahmad, S. F.; Bekta, J. M.; Tokarz, M.; Bardelle, Catherine; Hughes, Gareth; Patel, Bhavika; Thomason, Andrew; Cadogan, Elaine; Barrett, Ian; Lau, Alan; Pass, Martin; Valerie, Kristoffer 分享 收藏
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Peptide Library Approach to Uncover Phosphomimetic Inhibitors of the BRCA1 C-Terminal Domain White, E. Railey; Sun, Luxin; Ma, Zhong; Beckta, Jason M.; Danzig, Brittany A.; Hacker, David E.; Huie, Melissa; Williams, David C.; Edwards, Ross A.; Valerie, Kristoffer; Glover, J. N. Mark; Hartman, Matthew C. T. 分享 收藏
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