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J

Joëlle Wiels

centre national de la recherche scientifique (cnrs)

H指数:36

被引数:1.0万

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The pro-apoptotic peptide PEP-010 triggers apoptosis in pancreatic tumor models in monotherapy and in combination with gemcitabine independently of the KRAS status

促凋亡肽PEP-010在单药治疗和联合吉西他滨治疗中，能够独立于KRAS状态触发胰腺肿瘤模型的凋亡。

IF10.1

2025-07-010

PRE

The proapoptotic peptide PEP-010 is efficient on several models of different tumor origins and it can be monitored by pharmacodynamic biomarker candidates in clinical practice

CANCER RESEARCH

IF16.6

2023-04-042

PRE

Epstein-Barr virus reactivation induces MYC-IGH spatial proximity and t(8;14) in B cells

JOURNAL OF MEDICAL VIROLOGY

IF4.6

2023-03-137

OA

In vitro evaluation of NA1-115-7-loaded nanoemulsions, an MCL-1-specific inhibitor of natural origin, intended to treat B-cell lymphoproliferative disorders after oral administration

INTERNATIONAL JOURNAL OF PHARMACEUTICS

IF5.2

2023-01-010

OAAI

NA1-115-7, from Zygogynum pancheri, is a new selective MCL-1 inhibitor inducing the apoptosis of hematological cancer cells but non-toxic to normal blood cells or cardiomyocytes

BIOMEDICINE & PHARMACOTHERAPY

IF7.5

2022-10-019

OAAI

Shiga Toxins as Antitumor Tools

IF4

2021-09-2818

OAAI

Drimane Derivatives as the First Examples of Covalent BH3 Mimetics that Target MCL-1

IF3.4

2021-03-239

OAAI

The BCL-2 family protein inhibitor ABT-737 as an additional tool for the treatment of EBV-associated post-transplant lymphoproliferative disorders

MOLECULAR ONCOLOGY

IF4.5

2020-08-1214

OAAI

Verotoxin-1-Induced ER Stress Triggers Apoptotic or Survival Pathways in Burkitt Lymphoma Cells

IF4

2020-05-118

OAAI

Transient stabilization, rather than inhibition, of MYC amplifies extrinsic apoptosis and therapeutic responses in refractory B-cell lymphoma (vol 33, pg 2429, 2019)

IF13.4

2019-11-220

PREAI

Transient stabilization, rather than inhibition, of MYC amplifies extrinsic apoptosis and therapeutic responses in refractory B-cell lymphoma

IF13.4

2019-03-2622

OAAI

Developmental and cancer-associated plasticity of DNA replication preferentially targets GC-poor, lowly expressed and late-replicating regions (vol 46, pg 10157, 2018)

NUCLEIC ACIDS RESEARCH

IF13.1

2018-09-134

OAAI

Developmental and cancer-associated plasticity of DNA replication preferentially targets GC-poor, lowly expressed and late-replicating regions

NUCLEIC ACIDS RESEARCH

IF13.1

2018-09-0522

OAAI

Dual inhibitors of the pro-survival proteins Bcl-2 and Mcl-1 derived from natural compound meiogynin A

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

IF5.9

2018-03-0120

PREAI

Differential role of FL-BID and t-BID during verotoxin-1-induced apoptosis in Burkitt's lymphoma cells

IF7.3

2018-02-1416

OAAI

Natural Variation of Epstein-Barr Virus Genes, Proteins, and Primary MicroRNA

Epstein-barr病毒基因，蛋白质和主要MicroRNA的自然变异

JOURNAL OF VIROLOGY

IF3.8

2017-08-0173

OAAI

HIV Tat induces a prolonged MYC relocalization next to IGH in circulating B-cells

IF13.4

2017-03-3144

PREAI

Constitutive autophagy contributes to resistance to TP53-mediated apoptosis in Epstein-Barr virus-positive latency III B-cell lymphoproliferations

IF14.3

2016-01-0629

OA

Treatment with a BH3 mimetic overcomes the resistance of latency III EBV (+) cells to p53-mediated apoptosis

CELL DEATH & DISEASE

IF9.6

2011-07-2817

OAAI

Caspase-8-mediated cleavage of Bid and protein phosphatase 2A-mediated activation of Bax are necessary for Verotoxin-1-induced apoptosis in Burkitt's lymphoma cells

CELLULAR SIGNALLING

IF3.7

2010-03-0125

PREAI