未登录

C

Chun-Ho Wong

University of Illinois System

H指数:15

被引数:913

个人简介

暂无内容

教育背景

暂无内容

工作经历

暂无内容

荣誉奖项

暂无内容

CAG RNAs induce DNA damage and apoptosis by silencing NUDT16 expression in polyglutamine degeneration

CAG rna通过沉默NUDT16表达诱导多聚谷氨酰胺变性中的DNA损伤和凋亡

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2021-05-0416

OAAI

Exclusion of unsuitable CNS drug candidates based on their physicochemical properties and unbound fractions in biomatrices for brain microdialysis investigations

JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS

IF3.1

2020-01-013

PREAI

AQAMAN, a bisamidine-based inhibitor of toxic protein inclusions in neurons, ameliorates cytotoxicity in polyglutamine disease models

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2019-02-0110

OAAI

Efficient brain uptake and distribution of an expanded CAG RNA inhibitor DB213 via intranasal administration

EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES

IF4.7

2019-01-018

PREAI

Statistical Design of Experiment (DoE) based development and optimization of DB213 in situ thermosensitive gel for intranasal delivery

基于实验统计设计 (DoE) 的DB213原位温敏凝胶的开发和优化

INTERNATIONAL JOURNAL OF PHARMACEUTICS

IF5.2

2018-03-0132

PREAI

Demonstration of Direct Nose-to-Brain Transport of Unbound HIV-1 Replication Inhibitor DB213 Via Intranasal Administration by Pharmacokinetic Modeling

IF3.7

2017-12-2717

PREAI

Effective symptomatic treatment for severe and intractable pruritus associated with severe burn-induced hypertrophic scars: A prospective, multicenter, controlled trial

IF2.9

2016-08-0117

PREAI

A Potent Inhibitor of Protein Sequestration by Expanded Triplet (CUG) Repeats that Shows Phenotypic Improvements in a Drosophila Model of Myotonic Dystrophy

IF3.4

2016-06-0143

OAAI

Small Molecules that Target the Toxic RNA in Myotonic Dystrophy Type 2

IF3.4

2014-06-1729

OAAI

Targeting Toxic RNAs that Cause Myotonic Dystrophy Type 1 (DM1) with a Bisamidinium Inhibitor

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

IF15.6

2014-04-22102

OAAI

A Polymeric Fastener Can Easily Functionalize Liposome Surfaces with Gadolinium for Enhanced Magnetic Resonance Imaging

IF16

2013-10-1149

OA

Orthogonality in organic, polymer, and supramolecular chemistry: from Merrifield to click chemistry

CHEMICAL COMMUNICATIONS

IF4.2

2013-01-01271

PRE

Selective inhibition of MBNL1-CCUG interaction by small molecules toward potential therapeutic agents for myotonic dystrophy type 2 (DM2)†

NUCLEIC ACIDS RESEARCH

IF13.1

2011-07-1853

OAAI

Synthesis and Self Assembling Properties of Rod-Like, 2-Ureido-4-pyrimidinone-Based Main Chain Supramolecular Dendronized Polymers

IF5.2

2010-09-2817

PREAI

The Effects of Microenvironment Polarity and Dendritic Branching of Aliphatic Hydrocarbon Dendrons on the Self-Assembly of 2-Ureido-4-pyrimidinones

CHEMISTRY-AN ASIAN JOURNAL

IF3.3

2010-08-0213

PREAI

Generation-independent dimerization behavior of quadruple hydrogen-bond-containing oligoether dendrons

ORGANIC LETTERS

IF5

2006-04-0658

PREAI

Synthesis of new amphiphilic dendrons bearing aliphatic hydrocarbon surface sectors and a monocarboxylic or dicarboxylic acid focal point

ORGANIC LETTERS

IF5

2006-01-0426

PREAI