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To be, or not to be cleaved: Directed evolution of a canonical serine protease inhibitor against active and inactive protease pair identifies binding loop residue critical for prevention of proteolytic cleavage 存在与否被切割：针对活性与失活蛋白酶对的方向性进化研究，鉴定了经典的丝氨酸蛋白酶抑制剂中与预防蛋白水解切割相关的关键结合环残基 Koller, Zsombor; Nemeth, Balint Zoltan; Kiss, Bence; Nagy, Zoltan Attila; Schlosser, Gitta; Magyar, Csaba; Demcsak, Alexandra; Sahin-Toth, Miklos; Pal, Gabor 分享 收藏
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Praziquantel and factor H recruitment differentially affect the susceptibility of Schistosoma mansoni to complement-mediated damage van Beek, Anna E.; Jeanguenat, Hannah; Haberli, Cecile; Pouw, Richard B.; Lamers, Christina; Pal, Gabor; Gal, Peter; Schmidt, Christoph Q.; Ricklin, Daniel; Keiser, Jennifer 分享 收藏
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Complement inhibition can decrease the haemostatic response in a microvascular bleeding model at multiple levels Golomingi, Murielle; Kohler, Jessie; Lamers, Christina; Pouw, Richard B.; Ricklin, Daniel; Dobo, Jozsef; Gal, Peter; Pal, Gabor; Kiss, Bence; Dopler, Arthur; Schmidt, Christoph Q.; Hardy, Elaissa Trybus; Lam, Wilbur; Schroeder, Verena 分享 收藏
Synergy of protease-binding sites within the ecotin homodimer is crucial for inhibition of MASP enzymes and for blocking lectin pathway activation (vol 298, 101985, 2022) Nagy, Zoltan Attila; Heja, David; Bencze, Daniel; Kiss, Bence; Boros, Eszter; Szakacs, David; Fodor, Krisztian; Wilmanns, Matthias; Kocsis, Andrea; Dobo, Jozsef; Gal, Peter; Harmat, Veronika; Pal, Gabor 分享 收藏
Complement lectin pathway components MBL and MASP-1 promote haemostasis upon vessel injury in a microvascular bleeding model Golomingi, Murielle; Kohler, Jessie; Jenny, Lorenz; Hardy, Elaissa T.; Dobo, Jozsef; Gal, Peter; Pal, Gabor; Kiss, Bence; Lam, Wilbur A.; Schroeder, Verena 分享 收藏
Synergy of protease-binding sites within the ecotin homodimer is crucial for inhibition of MASP enzymes and for blocking lectin pathway activation Nagy, Zoltan Attila; Heja, David; Bencze, Daniel; Kiss, Bence; Boros, Eszter; Szakacs, David; Fodor, Krisztian; Wilmanns, Matthias; Kocsis, Andrea; Dobo, Jozsef; Gal, Peter; Harmat, Veronika; Pal, Gabor 分享 收藏
Directed Evolution-Driven Increase of Structural Plasticity Is a Prerequisite for Binding the Complement Lectin Pathway Blocking MASP-Inhibitor Peptides Durvanger, Zsolt; Boros, Eszter; Nagy, Zoltan Attila; Hegedus, Rozsa; Megyeri, Marton; Dobo, Jozsef; Gal, Peter; Schlosser, Gitta; Angyan, Annamaria F.; Gaspari, Zoltan; Perczel, Andras; Harmat, Veronika; Mezo, Gabor; Menyhard, Dora K.; Pal, Gabor 分享 收藏
Proprotein Convertase Is the Highest-Level Activator of the Alternative Complement Pathway in the Blood Oroszlan, Gabor; Dani, Rahel; Vegh, Barbara M.; Varga, Dora; Acs, Andrea, V; Pal, Gabor; Zavodszky, Peter; Farkas, Henriette; Gal, Peter; Dobo, Jozsef 分享 收藏
Altered glycosylation of IgG4 promotes lectin complement pathway activation in anti-PL A2R1-associated membranous nephropathy Haddad, George; Lorenzen, Johan M.; Ma, Hong; Haan, Noortje de; Seeger, Harald; Zaghrini, Christelle; Brandt, Simone; Kolling, Malte; Wegmann, Urs; Kiss, Bence; Pal, Gabor; Gal, Peter; Wuthrich, Rudolf P.; Wuhrer, Manfred; Beck, Laurence H.; Salant, David J.; Lambeau, Gerard; Kistler, Andreas D. 分享 收藏
Ecotin, a microbial inhibitor of serine proteases, blocks multiple complement dependent and independent microbicidal activities of human serum Nagy, Zoltan Attila; Szakacs, David; Boros, Eszter; Heja, David; Vigh, Eszter; Sandor, Noemi; Jozsi, Mihaly; Oroszlan, Gabor; Dobo, Jozsef; Gal, Peter; Pal, Gabor 分享 收藏
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MASP-1 Increases Endothelial Permeability Debreczeni, Marta L.; Nemeth, Zsuzsanna; Kajdacsi, Erika; Schwaner, Endre; Mako, Veronika; Masszi, Andras; Doleschall, Zoltan; Rigo, Janos; Walter, Fruzsina R.; Deli, Maria A.; Pal, Gabor; Dobo, Jozsef; Gal, Peter; Cervenak, Laszlo 分享 收藏
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Ecotin, a serine proteinase inhibitor from E. coli, is a potent complement inhibitor Szakacs, David; Nagy, Zoltan; Heja, David; Harmat, Veronika; Oroszlan, Gabor; Dobo, Jzsef; Gal, Peter; Pal, Gabor 分享 收藏
Cutting Edge: A New Player in the Alternative Complement Pathway, MASP-1 Is Essential for LPS-Induced, but Not for Zymosan-Induced, Alternative Pathway Activation Parej, Katalin; Kocsis, Andrea; Enyingi, Csenge; Dani, Rahel; Oroszlan, Gabor; Beinrohr, Laszlo; Dobo, Jozsef; Zavodszky, Peter; Pal, Gabor; Gal, Peter 分享 收藏
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