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L

L. David Sibley

Washington University School of Medicine

112H指数
361论文数
3.6W被引数
收录论文 166
发表时间
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Minimum Inoculum of Resistance Assay for Evaluating Antitoxoplasmosis Compounds That Target Phenylalanine tRNA Synthetase评估靶向苯丙氨酰-tRNA合成酶的抗弓形虫化合物的最小接种物抗性测定
errACS Infectious Diseases
IF3.8
err2026-06-18
err0
errOAAI
errTaher Uddin; Payal Mittal; Han Xie; Bruno Melillo; Amit Sharma; Arnab K. Chatterjee; L. David Sibley
err分享
err收藏
Lead Optimization of TgCDPK1 Inhibitors for the Treatment of Toxoplasmosis弓形虫钙调蛋白激酶1（TgCDPK1）抑制剂的临床前优化用于治疗弓形虫病
errJournal of Medicinal Chemistry
IF6.8
err2026-06-03
err0
PREAI
errMichael P. Mannino; Anusha Gokanapalle; Shrushti Patil; Anoopjit Singh Kooner; Chhuttan Lal Meena; Matthew Medcalf; Igi Vilza; Jennifer Barks; Yong Fu; Jing Xia; Jay C. Nix; Chris Nelson; Daved Fremont; Arun Dhillon; L. David Sibley; James W. Janetka
err分享
err收藏
Correction to “Improved Bicyclic Pyrrolidine Analogues Inhibit Toxoplasma gondii Growth In Vitro and Cure Infection In Vivo”
errJournal of Medicinal Chemistry
IF6.8
err2026-02-05
err0
PREAI
errTaher Uddin; Han Xie; Payal Mittal; Chloe Ence; Anil K. Gupta; Shrushti Patil; Christy Cho; Satavisha Banerjee; Amit Sharma; Bruno Melillo; Arnab K. Chatterjee; L. David Sibley
err分享
err收藏
Evolutionarily convergent mechanism of formin regulation coordinates actin polymerization in apicomplexan parasites顶复门寄生虫中formin调控的进化趋同机制协调肌动蛋白聚合化
errScience Advances
IF12.5
err2025-12-10
err0
errOAAI
errPengge Qian; Yong Fu; Jianwei Zeng; Michael J. Naldrett; Rui Zhang; L. David Sibley
err分享
err收藏
Atomic models of the Toxoplasma cell invasion machinery弓形虫细胞入侵机器的原子模型
errNature Structural & Molecular Biology
IF10.1
err2025-12-09
err0
errOAAI
errJianwei Zeng; Yong Fu; Pengge Qian; Wei Huang; Qingwei Niu; Wandy L. Beatty; Alan Brown; L. David Sibley; Rui Zhang
err分享
err收藏
Assessing the function of the alternative electron transport chain in the Cryptosporidium parvum mitosome评估隐孢子虫(Cryptosporidium parvum)米托体中替代电子传递链的功能
errMBIO
IF4.7
err2025-11-01
err1
PREAI
errDeng, Silu; Beatty, Wandy; Sibley, L. David
err分享
err收藏
Early life infection with Cryptosporidium parvum induces inflammatory responses to dietary antigens早期生活感染 Cryptosporidium parvum 会诱导对膳食抗原的炎症反应
errGut Microbes
IF11
err2025-08-28
err0
errOAAI
errIti Saraav; Wanyi Huang; Jisun Jung; Rui Xu; Yong Fu; Keely McDonald; Lawrence A. Schriefer; Rachel Rodgers; Megan T. Baldridge; Rodney D. Newberry; Chyi-Song Hsieh; L. David Sibley
err分享
err收藏
Cryptosporidium parvum multidrug resistance protein confers resistance to toxic gut microbial metaboliteCryptosporidium parvum多药耐药蛋白赋予对毒性肠道微生物代谢物的抗性
errCell Host & Microbe
IF18.7
err2025-08-27
err0
errOAAI
errWanyi Huang; Rui Xu; Abigail Kimball; William H. Witola; Megan T. Baldridge; Yaoyu Feng; Lihua Xiao; L. David Sibley
err分享
err收藏
Structure-Based Drug Design of Novel Heterocyclic Scaffolds as TgCDPK1 Inhibitors基于结构的药物设计：新型杂环骨架作为TgCDPK1抑制剂的研发
errChemMedChem
IF3.4
err2025-08-08
err0
PREAI
errAnoopjit Singh Kooner; Mariah Norman; Igi Vilza; Michael P. Mannino; Mary Savari Dhason; Jon Helander; Shrushti Patil; L. David Sibley; James W. Janetka
err分享
err收藏
Cryptosporidium Dense Granule Effector MUC5 Interacts with Host Actin Cytoskeleton through CD2AP隐孢子虫致密颗粒效应蛋白MUC5通过CD2AP与宿主肌动蛋白细胞骨架相互作用
errMicrobiological Research
IF6.9
err2025-07-19
err0
PREAI
errYangsiqi Ao; Fuxian Yang; Jieping Li; Xiaoqing Gong; Huimin Liu; Yilin Wu; Ping Zhu; Yanhua Xu; Na Li; Rui Xu; Yaqiong Guo; L. David Sibley; Lihua Xiao; Yaoyu Feng
err分享
err收藏
High-Throughput Repurposing Screen Reveals Compounds with Activity against Toxoplasma gondii Bradyzoites
errACS INFECTIOUS DISEASES
IF3.8
err2025-02-11
err0
PREAI
errUddin, Taher; Xia, Jing; Fu, Yong; Mcnamara, Case W.; Chatterjee, Arnab K.; Sibley, L. David
err分享
err收藏
Phospho-relay feedback loops control egress vs. intracellular development in Toxoplasma gondii磷酸化级联反馈回路调控弓形虫的细胞外排出与细胞内发育
errCELL REPORTS
IF6.9
err2025-02-01
err1
errOAAI
errClaywell, Ja E.; Fu, Yong; Sibley, L. David
err分享
err收藏
A combination of four Toxoplasma gondii nuclear-targeted effectors protects against interferon gamma-driven human host cell death
errMBIO
IF4.7
err2024-10-16
err3
errOAAI
errHenry, Brittany; Phillips, Aubrey J.; Sibley, L. David; Rosenberg, Alex
err分享
err收藏
Variant surface protein GP60 contributes to host infectivity of Cryptosporidium parvum
errCOMMUNICATIONS BIOLOGY
IF5.1
err2024-09-19
err3
errOAAI
errLi, Muxiao; Yang, Fuxian; Hou, Tianyi; Gong, Xiaoqing; Li, Na; Sibley, L. David; Feng, Yaoyu; Xiao, Lihua; Guo, Yaqiong
err分享
err收藏
Constitutive upregulation of transcription factors underlies permissive bradyzoite differentiation in a natural isolate of Toxoplasma gondii
errMBIO
IF4.7
err2024-09-11
err1
errOAAI
errXia, Jing; Fu, Yong; Huang, Wanyi; Uddin, Taher; Sibley, L. David
err分享
err收藏
Mendelian segregation and high recombination rates facilitate genetic analyses in Cryptosporidium parvum
errPLOS GENETICS
IF3.7
err2024-06-17
err0
errOAAI
errKimball, Abigail; Funkhouser-Jones, Lisa; Huang, Wanyi; Xu, Rui; Witola, William H.; Sibley, L. David
err分享
err收藏
Bicyclic Pyrrolidine Inhibitors of Toxoplasma gondii Phenylalanine t-RNA Synthetase with Antiparasitic Potency In Vitro and Brain Exposure
errACS INFECTIOUS DISEASES
IF3.8
err2024-05-14
err0
PREAI
errEnce, Chloe C.; Uddin, Taher; Borrel, Julien; Mittal, Payal; Xie, Han; Zoller, Jochen; Sharma, Amit; Comer, Eamon; Schreiber, Stuart L.; Melillo, Bruno; Sibley, L. David; Chatterjee, Arnab K.
err分享
err收藏
Susceptibility of Toxoplasma gondii to autophagy in human cells relies on multiple interacting parasite loci弓形虫对人类细胞自噬的敏感性依赖于多个相互作用的寄生虫基因座
errMBIO
IF4.7
err2024-01-16
err0
errOAAI
errRinkenberger, Nicholas; Rosenberg, Alex; Radke, Joshua B.; Bhushan, Jaya; Tomita, Tadakimi; Weiss, Louis M.; Sibley, L. David
err分享
err收藏
Multiple pathways for glucose phosphate transport and utilization support growth of Cryptosporidium parvum
errNATURE COMMUNICATIONS
IF15.7
err2024-01-09
err6
errOAAI
errXu, Rui; Beatty, Wandy L.; Greigert, Valentin; Witola, William H.; Sibley, L. David
err分享
err收藏
Cryptosporidium infection of human small intestinal epithelial cells induces type III interferon and impairs infectivity of Rotavirus
errGUT MICROBES
IF11
err2024-01-08
err6
errOAAI
errGreigert, Valentin; Saraav, Iti; Son, Juhee; Zhu, Yinxing; Dayao, Denise; Antia, Avan; Tzipori, Saul; Witola, William H.; Stappenbeck, Thaddeus S.; Ding, Siyuan; Sibley, L. David
err分享
err收藏

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暂无研究方向
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