logo
科言猫学术研究的AI总结
language
手机端手机端
  • Phone Feature微信小程序
简体中文简体中文
notice消息通知
博客博客
delete
arrow
返回
张章 封面图

张章 (Zhang Zhang)

jinan university

31H指数
149论文数
3.5K被引数
收录论文 75
发表时间
logo
Molecular Glues Recruiting RNF213 As an E3 Ligase for Targeted Protein Degradation: A Minimal Dibromoacetamide Warhead As a Recruitment Ligand分子胶水招募RNF213作为E3泛素连接酶进行靶向蛋白降解：作为招募配体的最小二溴乙酰胺基战争头
errJournal of the American Chemical Society
IF15.6
err2026-06-23
err0
PREAI
errJingyi Jiang; Yubin Chen; Rui Wan; Chaoming Huang; Tao Xiang; Chuixing Luo; Jianxiong Deng; Zhang Zhang; Tongzheng Liu; Yi Tan; Zhengqiu Li
err分享
err收藏
Palladium-Catalyzed Dynamic Kinetic Desymmetrization: Enantioselective Construction of Atropisomers with Contiguous Stereocenters钯催化动态动力学去对称化：构建具有连续立体中心的轴手性异构体
errOrganic Letters
IF5
err2026-06-05
err0
PREAI
errKaifeng Chen; Chun-Dong Huang; Binhong Tan; Miao Sun; Haoyuan Lin; Zhang Zhang; Shao-Fei Ni; Yue Zhang; Zhaodong Li
err分享
err收藏
Design; Synthesis; and Antitumor Evaluation of Novel Shikonin Derivatives: Discovery of 3k as a Dual Activator of the Integrated Stress Response and ROS in Gastric Cancer设计、合成及新型紫草素衍生物的抗肿瘤评价：发现3k为胃癌中整合应激反应和ROS的双激活剂
errJournal of Medicinal Chemistry
IF6.8
err2026-05-28
err0
PREAI
errBei Zhang; Zhipeng Xu; Danmei Tian; Fangfang Wang; Min Zhao; Ping Hu; Youwei Zhang; Zhang Zhang; Jinshan Tang
err分享
err收藏
Discovery of FYJ-195 as a Highly Potent FLT3 Inhibitor against Multiple Acquired Resistance Mutations in Acute Myeloid LeukemiaFYJ-195作为针对急性髓系白血病中多种获得性耐药突变的强效FLT3抑制剂的发现
errJournal of Medicinal Chemistry
IF6.8
err2026-05-23
err0
PREAI
errJin Yang; Ling-Yu Zhang; Xing-Feng Ni; Ming-Yu Bai; Xu Wang; An-Qi Fu; Min-Hui Chen; Meng-Yuan Zhang; Nuo Qiao; Zi-Xuan Wang; Qing-Qing Li; Shu Cai; Ying Wang; Yu-Sheng Yao; Yan-Cheng Yu; Wei-Dong Chen; Shan-Liang Sun; Zhang Zhang; Nian-Guang Li; Zhi-Hao Shi
err分享
err收藏
Cell-Active, Irreversible Covalent Inhibitors Targeting a Surface-Exposed Non-Catalytic Lysine on Aurora a Kinase by Using Squarate Chemistry细胞活性、不可逆共价抑制剂通过使用四嗪化学靶向Aurora a激酶表面暴露的非催化赖氨酸
errAngewandte Chemie International Edition
IF0
err2025-08-28
err0
PREAI
errZuqin Wang; Xuan Wang; Yong Li; Peishan Li; Shengjie Huang; Peng Chen; Guanghui Tang; Xiaotong Ding; Prof. Dr. Zhang Zhang; Prof. Dr. Zhi-Min Zhang; Prof. Dr. Yang Zhou; Prof. Dr. Shao Q. Yao; Prof. Dr. Xiaoyun Lu
err分享
err收藏
Discovery of 3,5-diaryl-1H-pyrazol-based ureas as potent RET inhibitors (vol 251, 115237, 2023)3,5-二芳基-1H-吡唑基-脲作为强效RET抑制剂的发现 (vol 251, 115237, 2023)
errEUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
IF5.9
err2025-07-01
err0
PREAI
errWu, Kaifu; He, Rui; Li, Zongyang; Qiu, Kongxi; Xiao, Guorong; Peng, Lijie; Meng, Xiangbao; Zheng, Canhui; Zhang, Zhang; Cai, Qian
err分享
err收藏
Discovery of Airway-Administered Ionophores for Mn2+ to Mitigate Lung Metastasis by Targeting Disseminated Tumor Cell经气道给药的Mn2+离子载体发现：通过靶向转移性肿瘤细胞以减轻肺转移
errACS NANO
IF16
err2025-04-03
err0
PREAI
errWang, YM; Fan, N; Wang, R; Li, X; Zhao, F; Miao, L; Wang, X; Yan, XH; Zhang, Z; Wu, XJ; Gao, ZG; Li, YF; Li, YB
err分享
err收藏
Discovery of a first-in-class PROTAC degrader of histone lysine demethylase KDM4
errEUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
IF5.9
err2025-04-01
err0
PREAI
errRao, Danni; Wang, Yiting; Yang, Xiaolong; Chen, Zhiwen; Wu, Feifei; Ren, Ran; Sun, Yaoliang; Lai, Yuanhui; Peng, Lijie; Yu, Lei; Zhang, Zhang; Xu, Shilin
err分享
err收藏
Designing Macrocyclic Kinase Inhibitors Using Macrocycle Scaffold Hopping with Reinforced Learning (Macro-Hop)使用宏观骨架跳跃（Macro-Hop）与强化学习设计大环激酶抑制剂
errJOURNAL OF MEDICINAL CHEMISTRY
IF6.8
err2025-03-18
err0
PREAI
errLiang, Hong; Huang, Shengjie; Xu, Xinxin; Yin, Zhao; Hussain, Muzammal; Song, Xiaojuan; Yi, Jianqiao; He, Yingqi; Guo, Jing; Tu, Zhengchao; Zhang, Zhang; Zhou, Yang; Lu, Xiaoyun
err分享
err收藏
Retesting HER2 Status of Axillary Lymph Node Metastases for Breast Cancer Patients with Minor HER2 Amplified Clone in the Primary Tumors: Does it has Clinical Significance?
errLABORATORY INVESTIGATION
IF4.2
err2025-03-01
err0
PREAI
errYang, Jieliang; Chen, Min; Peng, Heng; Zhang, Zhang; Wu, Yingyue; Wei, Bing
err分享
err收藏
Discovery of CZY43 as a new small-molecule degrader of pseudokinase HER3
errEUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
IF5.9
err2025-03-01
err0
PREAI
errChen, Zhiyuan; He, Rui; Huang, Shengjie; Zhou, Yang; Zhang, Zhang; Wang, Zhen; Ding, Ke
err分享
err收藏
Design, synthesis and evaluation of (E)-1-(4-(2-(1H-pyrazol-5-yl)vinyl) phenyl) derivatives as next generation selective RET inhibitors overcoming RET solvent front mutations (G810C/R)
errEUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
IF5.9
err2025-03-01
err0
PREAI
errXu, Mingjin; Wu, Kaifu; He, Rui; He, Jiahuan; Yang, Gangpeng; Ma, Haowen; Peng, Lijie; Zhang, Shuyao; Tan, Li; Zhang, Zhang; Cai, Qian
err分享
err收藏
Discovery of the first examples of right open reading frame kinase 2 (RIOK2) molecular glue degraders发现右开放阅读框激酶2 (RIOK2) 分子胶降解剂的第一个例子
errEUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
IF5.9
err2025-02-01
err0
PREAI
errMa, Haowen; Liu, Cong; Li, Zihao; Yu, Qiuchun; Xiong, Huilan; Huang, Chaomin; Tan, Li; Zhan, Min; Zhang, Zhang; Cai, Qian
err分享
err收藏
RETRACTION: Screening and identification of susceptibility genes for cervical cancer via bioinformatics analysis and the construction of an mitophagy-related genes diagnostic model撤稿：通过生物信息学分析和构建线粒体自噬相关基因诊断模型来筛查和鉴定宫颈癌易感基因
errJOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY
IF2.8
err2025-01-23
err0
errOAAI
errZhang, Zhang; Chen, Fangfang; Deng, Xiaoxiao
err分享
err收藏
Discovery of an Efficacious RET PROTAC Degrader with Enhanced Antiproliferative Activity against Resistant Cancer Cells Harboring RET Solvent-Front Mutations
errJOURNAL OF MEDICINAL CHEMISTRY
IF6.8
err2024-12-28
err0
PREAI
errZhang, Qian; He, Yingqi; Rao, Danni; He, Rui; Yu, Lei; Sun, Yaoliang; Lai, Yuanhui; Shi, Zihan; Peng, Lijie; Zhang, Zhang; Xu, Shilin
err分享
err收藏
MAFDE-DN4: Improved Few-shot plant disease classification method based on Deep Nearest Neighbor Neural Network
errCOMPUTERS AND ELECTRONICS IN AGRICULTURE
IF8.9
err2024-11-01
err0
PREAI
errZhao, Yun; Zhang, Zixin; Wu, Na; Zhang, Zhang; Xu, Xing
err分享
err收藏
OGG1: An emerging multifunctional therapeutic target for the treatment of diseases caused by oxidative DNA damage
errMEDICINAL RESEARCH REVIEWS
IF11.6
err2024-08-09
err2
errOAAI
errZhong, Yunxiao; Zhang, Xinya; Feng, Ruibing; Fan, Yu; Zhang, Zhang; Zhang, Qing-Wen; Wan, Jian-Bo; Wang, Yitao; Yu, Hua; Li, Guodong
err分享
err收藏
Encoding and display technologies for combinatorial libraries in drug discovery: The coming of age from biology to therapy
errACTA PHARMACEUTICA SINICA B
IF14.6
err2024-08-01
err7
errOAAI
errFan, Yu; Feng, Ruibing; Wang, Zhen-Liang; Zhang, Xinya; Xiong, Feng; Zhang, Shuihua; Zhong, Zhang-Feng; Yu, Hua; Zhang, Qing-Wen; Zhang, Zhang; Wang, Yitao; Li, Guodong
err分享
err收藏
Unraveling Reactivity Differences: Room-Temperature Ring-Opening Metathesis Polymerization (ROMP) versus Frontal ROMP
errJOURNAL OF THE AMERICAN CHEMICAL SOCIETY
IF15.6
err2024-03-05
err7
PREAI
errLessard, Jacob J.; Mejia, Edgar B.; Kim, Abbie J.; Zhang, Zhang; Berkey, Mya G.; Medina-Barreto, Zina S.; Ewoldt, Randy H.; Sottos, Nancy R.; Moore, Jeffrey S.
err分享
err收藏
Novel Covalent Probe Selectively Targeting Glutathione Peroxidase 4 In Vivo: Potential Applications in Pancreatic Cancer Therapy
errJOURNAL OF MEDICINAL CHEMISTRY
IF6.8
err2024-01-24
err4
PREAI
errTang, Zifeng; Li, Jie; Peng, Lijie; Xu, Fang; Tan, Yi; He, Xiaoqiang; Zhu, Chengjun; Zhang, Zhi-Min; Zhang, Zhang; Sun, Pinghua; Ding, Ke; Li, Zhengqiu
err分享
err收藏

研究方向

小分子靶向抗肿瘤药物的作用、机制及开发研究肿瘤耐药机制及克服耐药的新方法研究基于表型筛选进行药物及疾病的靶标发现研究
合作学者
合作期刊
J
Jeffrey S. Moore
H 指数: 126 · 论文数: 854
陈
陈敏 (Min Chen)
H 指数: 105 · 论文数: 1.5K
N
Nancy R. Sottos
H 指数: 90 · 论文数: 510
X
Xumu Zhang
H 指数: 86 · 论文数: 759
D
Duanqing Pei
H 指数: 84 · 论文数: 457
查看更多