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C

Christian W. Gruber

Medical University of Vienna

43H指数
156论文数
1.2W被引数
收录论文 72
发表时间
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Design of sunflower trypsin inhibitor 1 derived probes targeting the LDLR and evaluation of their brain delivery向日葵胰蛋白酶抑制剂1衍生的靶向LDLR探针的设计及其脑递送评价
errBIOMEDICINE & PHARMACOTHERAPY
IF7.5
err2026-07-30
err0
errOAAI
errPaula Schwarz; Jonathan Dieringer; Kirtikumar B. Jadhav; Maria C. Lucana; Aghavni Ginosyan; Benjamí Oller-Salvia; Christian W. Gruber; Irena Loryan; Roland Hellinger
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Structural and functional basis of antinociceptive action of χ-conotoxin AoIA at the noradrenaline transporterχ-芋螺毒素AoIA在去甲肾上腺素转运蛋白上的镇痛作用的结构和功能基础
errNATURE STRUCTURAL & MOLECULAR BIOLOGY
IF10.1
err2026-07-21
err0
errOAAI
errOliver J. V. Belleza; Heng Zhang; Helmut Schmidhammer; Tye I. Gonzalez; Cosmin I. Ciotu; Nataša Tomašević; Carlo Martin M. Ocampo; Jomari C. Fernando; Johannes Koehbach; Paula Schwarz; Mounaf Al Makhlouf; Gabor Tajti; Simon Hasinger; Nina Kastner; Orcun Avsar; Bernhard Retzl; Kathrin Jäntsch; Yi Jiang; Roland Hellinger; Michael J. M. Fischer; K. Johan Rosengren; Christian W. Gruber; Aaron Joseph L. Villaraza; Thomas Stockner; Mariana Spetea; H. Eric Xu; Harald H. Sitte
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Peptide ligand discovery of G protein-coupled receptorsG蛋白偶联受体肽配体的发现
errNature Reviews Methods Primers
IF56
err2026-07-16
err0
PREAI
errJulius Hermes; Marin Matic; Ho Yan Yeung; Qianru Jiang; Lauri Urvas; Elizaveta Korchevaya; Tomasz Stepniewski; Alexandre Murza; Jana Selent; Michael Freissmuth; Christian Heinis; Pierre-Luc Boudreault; Jens Carlsson; Tao Che; Helena Safavi-Hemami; Alexander S. Hauser; Christian W. Gruber
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Tropical psychotria plants are a rich source for peptide inhibitors of human prolyl oligopeptidase热带 Psychotria 植物是人体脯氨酰寡肽酶肽抑制剂的丰富来源
errNatural Products and Bioprospecting
IF4.9
err2026-04-14
err0
errOAAI
errRoland Hellinger; Paula Schwarz; Jonathan Dieringer; Carina Ebermann; Kirtikumar B. Jadhav; Markus Muttenthaler; Christian W. Gruber
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β-Arrestins and disease-linked variants: opportunities for targeted modulationΒ-抑制蛋白和疾病相关变异: 靶向调节的机会
errTrends in Pharmacological Sciences
IF19.9
err2026-03-03
err0
errOAAI
errSimon Hasinger; Andreas Fraunhofer; Julius Hermes; Peter J. McCormick; Christian W. Gruber
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The Concise Guide to PHARMACOLOGY 2025/26: G protein-coupled receptors《简明药理学指南2025/26：G蛋白偶联受体》
errBritish Journal of Pharmacology
IF7.7
err2025-12-01
err29
errOAAI
errAlexander, Stephen P. H.; Davenport, Anthony P.; Kelly, Eamonn; Gibb, Alasdair J.; Mathie, Alistair A.; Peach, Chloe J.; Veale, Emma L.; Armstrong, Jane F.; Faccenda, Elena; Harding, Simon D.; Southan, Christopher; Davies, Jamie A.; Abbracchio, Maria Pia; Abraham, George R.; Agoulnik, Alexander; Alexander, Wayne; Al-hosaini, Khaled; Back, Magnus; Baker, Jillian G.; Barnes, Nicholas M.; Bathgate, Ross; Beaulieu, Jean-Martin; Beck-Sickinger, Annette G.; Behrens, Maik; Bennett, Kirstie A.; Bernstein, Kenneth E.; Bettler, Bernhard; Birdsall, Nigel J. M.; Blaho, Victoria A.; Bonaventure, Pascal; Boulay, Francois; Bousquet, Corinne; Brauner-Osborne, Hans; Brown, Andrew J.; Burnstock, Geoffrey; Busnelli, Marta; Calo, Girolamo; Caruso, Vanni; Castano, Justo P.; Catt, Kevin J.; Ceruti, Stefania; Chazot, Paul; Chiang, Nan; Chini, Bice; Christopoulos, Arthur; Chun, Jerold; Cianciulli, Antonia; Civelli, Olivier; Clapp, Lucie H.; Couture, Rejean; Cox, Helen M.; Csaba, Zsolt; Dahlgren, Claes; Dautzenberg, Frank M.; Dent, Gordon; Douglas, Steven D.; Dournaud, Pascal; Dubocovich, Margarita L.; Eguchi, Satoru; Escher, Emanuel; Filardo, Edward J.; Fong, Tung; Forsman, Huamei Fu; Fumagalli, Marta; Gainetdinov, Raul R.; Garelja, Michael L.; de Gasparo, Marc; Gbahou, Florence; Gerard, Craig; Gershengorn, Marvin; Glass, Michelle; Gloriam, David E.; Gobeil, Fernand; Goodfriend, Theodore L.; Goudet, Cyril; Gratz, Lukas; Gregory, Karen J.; Gruber, Christian; Gundlach, Andrew L.; Hamann, Jorg; Hanson, Julien; Hartman, Deborah S.; Hauger, Richard L.; Hay, Debbie L.; Heinemann, Akos; Heitman, Laura; Herr, Deron R.; Hollenberg, Morley D.; Holliday, Nicholas D.; Holst, Birgitte; Horiuchi, Mastgugu; Hoyer, Daniel; Hunyady, Laszlo; Husain, Ahsan; IJzerman, Adriaan P.; Inagami, Tadashi; Insel, Paul A.; Jacobson, Kenneth A.; Jacobson, Laura H.; Jensen, Robert T.; Jockers, Ralf; Jonnalagadda, Deepa; Karnik, Sadashiva; Kaupmann, Klemens; Kemp, Jacqueline; Kennedy, Charles; Kihara, Yasuyuki; Kinsolving, Julia; Kitazawa, Takio; Kozielewicz, Pawel; Kreienkamp, Hans-Juergen; Kukkonen, Jyrki P.; Laishram, Luxmichan; Langenhan, Tobias; Langmead, Christopher J.; Larhammar, Dan; Leach, Katie; Lecca, Davide; Lee, John D.; Leeman, Susan E.; Leprince, Jerome; Leurs, Rob; Li, Xaria X.; Liebscher, Ines; Lolait, Stephen J.; Lupp, Amelie; Macrae, Robyn; Maguire, Janet J.; Malfacini, Davide; Manning, Maurice; Marangon, Davide; Martemyanov, Kirill; Mazella, Jean; McArdle, Craig A.; Melmed, Shlomo; Michel, Martin C.; Miller, Laurence J.; Mitolo, Vincenzo; Mouillac, Bernard; Mueller, Christa E.; Murphy, Philip M.; Nahon, Jean-Louis; Neubig, Richard R.; Ngo, Tony; Norel, Xavier; Nyimanu, Duuamene; O'Carroll, Anne-Marie; Offermanns, Stefan; Panaro, Maria Antonietta; Parmentier, Marc; Perry-Hauser, Nicole; Pertwee, Roger G.; Pin, Jean-Philippe; Prossnitz, Eric R.; Qin, Helena Chengxue; Quinn, Mark; Raffaele, Stefano; Ramachandran, Rithwik; Ray, Manisha; Reinscheid, Rainer K.; Buzon, Alejandro Romeral; Rondard, Philippe; Rosenkilde, Mette M.; Rovati, G. Enrico; Ruzza, Chiara; Sanger, Gareth J.; Scholz, Nicole; Schoeneberg, Torsten; Schulte, Gunnar; Schulz, Stefan; Segaloff, Deborah L.; Serhan, Charles N.; Shukla, Arun K.; Singh, Khuraijam Dhanachandra; Smith, Craig M.; Smith, Nicola J.; Staeubert, Claudia; Stoddart, Leigh A.; Sugimoto, Yukihiko; Summers, Roger; Tan, Valerie P.; Thal, David M.; Thomas, Walter (Wally); Timmermans, Pieter B. M. W. M.; Tirupula, Kalyan; Toll, Lawrence; Tulipano, Giovanni; Unal, Hamiyet; Unger, Thomas; Valant, Celine; Vanderheyden, Patrick; Vaudry, David; Vaudry, Hubert; Verbalis, Joseph G.; Vilardaga, Jean-Pierre; Walker, Christopher S.; Wang, Ji Ming; Ward, Donald T.; Wester, Hans-Juergen; Willars, Gary B.; Williams, Tom Lloyd; Woodruff, Trent M.; Wu, Huixian; Yang, Cheng; Yao, Chengcan; Ye, Richard D.; Zaidman, Nathan
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Fluorescent Peptide Tracers for Simultaneous Oxytocin Receptor Activation and Visualization荧光肽示踪剂用于同时激活催产素受体和可视化
errAngewandte Chemie International Edition
IF0
err2025-09-26
err0
errOAAI
errMonika Perisic Böhm; Predrag Kalaba; Rachel S. Gormal; Maja Zupančič; Alexandra Wolf; Mia Juračić; Thomas Kremsmayr; Frédéric A. Meunier; Thierry Langer; Christian W. Gruber; Erik Keimpema; Markus Muttenthaler
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Biodiversity2Drugs—Renaissance of exploring nature-derived peptides for GPCR ligand discoveryBiodiversity2Drugs—探索天然来源多肽以发现GPCR配体的复兴
errBritish Journal of Pharmacology
IF7.7
err2025-05-29
err0
errOAAI
errChristian W. Gruber; Isabel Beets; Pierre-Luc Boudreault; Vanderlan da S. Bolzani; Jens Carlsson; Pedro A. Fernandes; Michael Freissmuth; Nicolas Gilles
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Structural and Functional Characterization of a Novel KOR-Selective Peptide-Drug Conjugate Ligand, DNCP-(3-NalA新型KOR选择性肽-药物偶联物配体DNCP-(3-NalA)的结构与功能表征
errJOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS
IF3.8
err2025-03-01
err0
PREAI
errHan, Jianming; Muratspahic, Edin; Deibler, Kristine; Tomasevic, Natasa; Jadhav, Kirtikumar Bhaskarrao; Marti, Aina-leonor Olive; Hellinger, Roland; Koehbach, Johannes; Fay, Jonathan F.; Che, Tao; Baker, David; Gruber, Christian W.; Appourchaux, Kevin; Majumdar, Susruta
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Discovery and development of macrocyclic peptide modulators of the cannabinoid 2 receptor
errJOURNAL OF BIOLOGICAL CHEMISTRY
IF3.9
err2024-06-01
err1
errOAAI
errTomasevic, Natasa; Emser, Fabiola Susanna; Muratspahic, Edin; Gattringer, Jasmin; Hasinger, Simon; Hellinger, Roland; Keov, Peter; Felkl, Manuel; Gertsch, Jurg; Becker, Christian F. W.; Gruber, Christian W.
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Flipping the GPCR Switch: Structure-Based Development of Selective Cannabinoid Receptor 2 Inverse Agonists
errACS CENTRAL SCIENCE
IF10.4
err2024-03-11
err5
errOAAI
errKosar, Miroslav; Sarott, Roman C.; Sykes, David A.; Viray, Alexander E. G.; Vitale, Rosa Maria; Tomasevic, Natasa; Li, Xiaoting; Ganzoni, Rudolf L. Z.; Kicin, Bilal; Reichert, Lisa; Patej, Kacper J.; Gomez-Bouzo, Uxia; Guba, Wolfgang; McCormick, Peter J.; Hua, Tian; Gruber, Christian W.; Veprintsev, Dmitry B.; Frank, James A.; Grether, Uwe; Carreira, Erick M.
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Chemical synthesis of grafted cyclotides using a plug and play approach
errRSC CHEMICAL BIOLOGY
IF3.1
err2024-01-01
err1
errOAAI
errKoehbach, Johannes; Muratspahic, Edin; Ahmed, Zakaria M.; White, Andrew M.; Tomasevic, Natasa; Durek, Thomas; Clark, Richard J.; Gruber, Christian W.; Craik, David J.
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Design, synthesis, conformational analysis, and biological activity of Cα1-to-Cα6 1,4-and 4,1-disubstituted 1H-[1,2,3]triazol-1-yl-bridged oxytocin analogues
errJOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY
IF5.4
err2023-09-21
err1
errOAAI
errNuti, Francesca; Larregola, Maud; Staskiewicz, Agnieszka; Retzl, Bernhard; Tomasevic, Natasa; Macchia, Lorenzo; Street, Maria E.; Jewginski, Michal; Lequin, Olivier; Latajka, Rafal; Rovero, Paolo; Gruber, Christian W.; Chorev, Michael; Papini, Anna Maria
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Development of a Selective Peptide κ-Opioid Receptor Antagonist by Late-Stage Functionalization with Cysteine Staples
errJOURNAL OF MEDICINAL CHEMISTRY
IF6.8
err2023-08-26
err7
errOAAI
errMuratspahic, Edin; White, Andrew M.; Ciotu, Cosmin I.; Hochrainer, Nadine; Tomasevic, Natasa; Koehbach, Johannes; Lewis, Richard J.; Spetea, Mariana; Fischer, Michael J. M.; Craik, David J.; Gruber, Christian W.
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Peptide modulators of cell migration: Overview, applications and future development
errDRUG DISCOVERY TODAY
IF7.5
err2023-05-01
err5
errOAAI
errGattringer, Jasmin; Gruber, Christian W.; Hellinger, Roland
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Multiplexed neuropeptide mapping in ant brains integrating microtomography and three-dimensional mass spectrometry imaging
errPNAS NEXUS
IF3.8
err2023-04-25
err4
errOAAI
errGeier, Benedikt; Gil-Mansilla, Esther; Liutkeviciute, Zita; Hellinger, Roland; Vanden Broeck, Jozef; Oetjen, Janina; Liebeke, Manuel; Gruber, Christian W.
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The nature inspired peptide [T20K]-kalata B1 induces anti-tumor effects in anaplastic large cell lymphoma
errBIOMEDICINE & PHARMACOTHERAPY
IF7.5
err2022-09-01
err2
PREAI
errLind, Judith; Hellinger, Roland; Kudweis, Petra; Moll, Herwig P.; Gattringer, Jasmin; Thell, Kathrin; Edtmayer, Sophie; Gruber, Christian W.; Stoiber, Dagmar; Kollmann, Karoline
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Ipecac root extracts and isolated circular peptides differentially suppress inflammatory immune response characterised by proliferation, activation and degranulation capacity of human lymphocytes in vitro
errBIOMEDICINE & PHARMACOTHERAPY
IF7.5
err2022-08-01
err4
errOAAI
errFalanga, Chiara Madlen; Steinborn, Carmen; Muratspahic, Edin; Zimmermann-Klemd, Amy Marisa; Winker, Moritz; Krenn, Liselotte; Huber, Roman; Gruber, Christian W.; Grundemann, Carsten
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Discovery of the cyclotide caripe 11 as a ligand of the cholecystokinin-2 receptor发现环肽caripe 11作为cholecystokinin-2受体的配体
errSCIENTIFIC REPORTS
IF3.9
err2022-06-02
err14
errOAAI
errTaghizadeh, Mohammad Sadegh; Retzl, Bernhard; Muratspahic, Edin; Trenk, Christoph; Casanova, Emilio; Moghadam, Ali; Afsharifar, Alireza; Niazi, Ali; Gruber, Christian W.
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Back to the Medicinal Chemistry Future
errJOURNAL OF MEDICINAL CHEMISTRY
IF6.8
err2021-11-01
err1
PREAI
errGiustiniano, Mariateresa; Gruber, Christian W.; Kent, Caitlin N.; Trippier, Paul C.
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