未登录 A Chiral Pool Strategy for the Synthesis of a SMARCA2 Degrading PROTAC Lee, Miseon; Wu, Jiang-Ping; Lee, Jaehee; Wang, Jun; White, Jada A. H.; Rugg, Kyle W.; Sienkiewicz, Alexander; Lorenz, Jon C.; Greb, Peter; Bunner, Matthew H.; Hirsh, David A.; Gonnella, Nina C.; Nordstrom, Fredrik L.; Kofink, Christiane; Weinstabl, Harald; Reeves, Jonathan T. 分享 收藏
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Practical Synthesis of Terminal Vinyl Fluorides Volchkov, Ivan; Powell, Brent V.; Zatolochnaya, Olga V.; Leung, Joyce C.; Pennino, Scott; Wu, Lifen; Gonnella, Nina C.; Bhaskararao, Bangaru; Kozlowski, Marisa C.; Reeves, Jonathan T. 分享 收藏
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Process Development for the Synthesis of BI 1702135: A Concise Design Enabled by Selective Acylation of a 2-Aminobenzimidazole Intermediate Wu, Jiang-Ping; Dong, Wei-Tong; Chen, Chengsheng; Sienkiewicz, Alexander; Beyer, Phouvieng; Wang, Jun; Haddad, Nizar; Lorenz, Jon C.; Reeves, Jonathan T.; Bunner, Matthew H.; Gonnella, Nina C.; Weinstabl, Harald; Garavel, Geraldine 分享 收藏
Process Development of the BACE Inhibitors BI 1147560 BS and BI 1181181 MZ Li, Guisheng; Tan, Zhulin; Xu, Yibo; Sidhu, Kanwar P. S.; Qu, Bo; Herbage, Melissa A.; Eriksson, Magnus C.; Zeng, Xingzhong; Busacca, Carl A.; Desrosiers, Jean-Nicolas; Hampel, Thomas; Niemeier, Oliver; Reichel, Carsten; Dang, Mai Thi Quynh; Schoerer, Marvin; Kemmer, Dirk; Eick, Melanie; Werle, Holger; Kim, Soojin; Li, Zhibin; Venkatraman, Shankar; Jia, Lanqi; Claremon, David A.; Fuchs, Klaus; Heine, Niklas; Byrne, Denis; Narayanan, Bikshandarkoil; Sarvestani, Max; Johnson, Joe; Premasiri, Ajith; Nummy, Larry J.; Lorenz, Jon C.; Haddad, Nizar; Gonnella, Nina C.; Pennino, Scott; Krawiec, Mariusz; Senanayake, Chris H.; Buono, Frederic; Lee, Heewon; Hossain, Azad; Song, Jinhua J.; Reeves, Jonathan T. 分享 收藏
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Start Selective and Rigidify: The Discovery Path toward a Next Generation of EGFR Tyrosine Kinase Inhibitors Engelhardt, Harald; Boese, Dietrich; Petronczki, Mark; Scharn, Dirk; Bader, Gerd; Baum, Anke; Bergner, Andreas; Chong, Eugene; Doebel, Sandra; Egger, Georg; Engelhardt, Christian; Ettmayer, Peter; Fuchs, Julian E.; Gerstberger, Thomas; Gonnella, Nina; Grimm, Andreas; Grondal, Elisabeth; Haddad, Nizar; Hopfgartner, Barbara; Kousek, Roland; Krawiec, Mariusz; Kriz, Monika; Lamarre, Lyne; Leung, Joyce; Mayer, Moriz; Patel, Nitinchandra D.; Simov, Biljana Peric; Reeves, Jonathan T.; Schnitzer, Renate; Schrenk, Andreas; Sharps, Bernadette; Solca, Flavio; Stadtmueller, Heinz; Tan, Zhulin; Wunberg, Tobias; Zoephel, Andreas; McConnell, Darryl B. 分享 收藏
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Rhodium-Catalyzed Addition of Aryl Boronic Acids to 2,2-Disubstituted Malononitriles Malapit, Christian A.; Caldwell, Donald R.; Luvaga, Irungu K.; Reeves, Jonathan T.; Volchkov, Ivan; Gonnella, Nina C.; Han, Zhengxu S.; Busacca, Carl A.; Howell, Amy R.; Senanayake, Chris H. 分享 收藏
Development of a 13C NMR Chemical Shift Prediction Procedure Using B3LYP/cc-pVDZ and Empirically Derived Systematic Error Correction Terms: A Computational Small Molecule Structure Elucidation Method Xin, Dongyue; Sader, C. Avery; Chaudhary, Om; Jones, Paul-James; Wagner, Klaus; Tautermann, Christofer S.; Yang, Zheng; Busacca, Carl A.; Saraceno, Reginaldo A.; Fandrick, Keith R.; Gonnella, Nina C.; Horspool, Keith; Hansen, Gordon; Senanayake, Chris H. 分享 收藏
Copper-Catalyzed Asymmetric Propargylation of Cyclic Aldimines Fandrick, Daniel R.; Hart, Christine A.; Okafor, Ifeanyi S.; Mercadante, Michael A.; Sanyal, Sanjit; Masters, James T.; Sarvestani, Max; Fandrick, Keith R.; Stockdill, Jennifer L.; Grinberg, Nelu; Gonnella, Nina; Lee, Heewon; Senanayake, Chris H. 分享 收藏
Structure Elucidation of Poly-Faldaprevir: Polymer Backbone Solved Using Solid-State and Solution Nuclear Magnetic Resonance Spectroscopy Poly-faldaprevir的结构阐明: 使用固态和溶液核磁共振谱解决的聚合物主链 Gonnella, Nina C.; Busacca, Carl A.; Zhang, Li; Saha, Anjan; Wu, Jiang-Ping; Li, Guisheng; Davis, Mark; Offerdahl, Thomas; Jones, Paul-James; Herfurth, Lars; Reddig, Tim; Wagner, Klaus; Niemann, Michael; Werthmann, Ulrike; Grupe, Julia; Roos, Helmut; Reckzuegel, Gaby; Ding, Andreas 分享 收藏
A Mild Dihydrobenzooxaphosphole Oxazoline/Iridium Catalytic System for Asymmetric Hydrogenation of Unfunctionalized Dialins Qu, Bo; Samankumara, Lalith P.; Ma, Shengli; Fandrick, Keith R.; Desrosiers, Jean-Nicolas; Rodriguez, Sonia; Li, Zhibin; Haddad, Nizar; Han, Zhengxu S.; McKellop, Keith; Pennino, Scott; Grinberg, Nelu; Gonnella, Nina C.; Song, Jinhua J.; Senanayake, Chris H. 分享 收藏
Facile Entry to an Efficient and Practical Enantioselective Synthesis of a Polycyclic Cholesteryl Ester Transfer Protein Inhibitor Han, Zhengxu S.; Xu, Yibo; Fandrick, Daniel R.; Rodriguez, Sonia; Li, Zhibin; Qu, Bo; Gonnella, Nina C.; Sanyal, Sanjit; Reeves, Jonathan T.; Ma, Shengli; Grinberg, Nelu; Haddad, Nizar; Krishnamurthy, Dhileep; Song, Jinhua J.; Yee, Nathan K.; Pfrengle, Waldemar; Ostermeier, Markus; Schnaubelt, Juergen; Leuter, Zeno; Steigmiller, Sonja; Daeubler, Juergen; Stehle, Emanuel; Neumann, Lukas; Trieselmann, Thomas; Tielmann, Patrick; Buba, Annette; Hamm, Rainer; Koch, Gunter; Renner, Svenja; Dehli, Juan R.; Schmelcher, Florian; Stange, Christian; Mack, Juergen; Soyka, Rainer; Senanayake, Chris H. 分享 收藏
Carbamoyl Anion Addition to N-Sulfinyl Imines: Highly Diastereoselective Synthesis of α-Amino Amides Reeves, Jonathan T.; Tan, Zhulin; Herbage, Melissa A.; Han, Zhengxu S.; Marsini, Maurice A.; Li, Zhibin; Li, Guisheng; Xu, Yibo; Fandrick, Keith R.; Gonnella, Nina C.; Campbell, Scot; Ma, Shengli; Grinberg, Nelu; Lee, Heewon; Lu, Bruce Z.; Senanayake, Chris H. 分享 收藏
Development of a Large Scale Asymmetric Synthesis of the Glucocorticoid Agonist BI 653048 BS H3PO4 Reeves, Jonathan T.; Fandrick, Daniel R.; Tan, Zhulin; Song, Jinhua J.; Rodriguez, Sonia; Qu, Bo; Kim, Soojin; Niemeier, Oliver; Li, Zhibin; Byrne, Denis; Campbell, Scot; Chitroda, Ashish; DeCroos, Phil; Fachinger, Thomas; Fuchs, Victor; Gonnella, Nina C.; Grinberg, Nelu; Haddad, Nizar; Jaeger, Burkhard; Lee, Heewon; Lorenz, Jon C.; Ma, Shengli; Narayanan, Bikshandarkoil A.; Nummy, Larry J.; Premasiri, Ajith; Roschangar, Frank; Sarvestani, Max; Shen, Sherry; Spinelli, Earl; Sun, Xiufeng; Varsolona, Richard J.; Yee, Nathan; Brenner, Michael; Senanayake, Chris H. 分享 收藏
Asymmetric Methallylation of Ketones Catalyzed by a Highly Active Organocatalyst 3,3′-F2-BINOL Zhang, Yongda; Li, Ning; Qu, Bo; Ma, Shengli; Lee, Heewon; Gonnella, Nina C.; Gao, Joe; Li, Wenjie; Tan, Zhulin; Reeves, Jonathan T.; Wang, Jun; Lorenz, Jon C.; Li, Guisheng; Reeves, Diana C.; Premasiri, Ajith; Grinberg, Nelu; Haddad, Nizar; Lu, Bruce Z.; Song, Jinhua J.; Senanayake, Chris H. 分享 收藏
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