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Lena M Kutscher

hopp childrens cancer center heidelberg

11H指数
63论文数
737被引数
收录论文 26
发表时间
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Divergent medulloblastoma chromatin states disclose KDM2B as a selective dependencyDivergent medulloblastoma chromatin states disclose KDM2B as a selective dependency 不同小脑髓母细胞瘤染色质状态揭示KDM2B为一种选择性依赖
errNature Genetics
IF29
err2026-09-24
err0
errOAAI
errRan Tao; Serap Erkek-Ozhan; Beisi Xu; Yurika Matsui; Priya Mittal; Kyle S. Smith; Yiran Li; David Filipovic; Ruijie Xu; Qingsong Gao; Emily Darrow; Rahul Kumar; Nadhir Djekidel; Richa Bajpai; Jennifer Hadley; Melissa Batts; Sara A. Lewis; Taha Soliman; Colleen Reilly; Natarajan V. Bhanu; Leena Paul; Hong Lin; Brian Gudenas; Kim Lowe; Marc Zapatka; Laura Sieber; David T. W. Jones; Marcel Kool; Sebastian M. Waszak; Volker Hovestadt; Ivo Buchhalter; Marina Ryzhova; Andrey Korshunov; Peter Lichter; Lukas Chavez; Lena M. Kutscher; Benjamin A. Garcia; Shondra M. Pruett-Miller; Xin Zhou; Brent A. Orr; Giles W. Robinson; Gang Wu; Jan O. Korbel; Jamy C. Peng; Stefan M. Pfister; Paul A. Northcott
err分享
err收藏
A photoreceptor state links aggressive brain tumors in children光感受器状态与儿童侵袭性脑肿瘤相关联
errCancer Cell
IF44.5
err2026-03-19
err0
PREAI
errStefan M. Pfister; Lena M. Kutscher
err分享
err收藏
The evolution of gene regulation in mammalian cerebellum development哺乳动物小脑发育过程中基因调控的进化
errScience
IF45.8
err2026-01-29
err0
PREAI
errIoannis Sarropoulos; Mari Sepp; Tetsuya Yamada; Philipp S. L. Schäfer; Nils Trost; Julia Schmidt; Céline Schneider; Charis Drummer; Sophie Mißbach; Ibrahim I. Taskiran; Nikolai Hecker; Carmen Bravo González-Blas; Robert Frömel; Piyush Joshi; Evgeny Leushkin; Frederik Arnskötter; Kevin Leiss; Konstantin Okonechnikov; Steven Lisgo; Miklós Palkovits; Svante Pääbo; Margarida Cardoso-Moreira; Lena M. Kutscher; Rüdiger Behr; Stefan M. Pfister; Stein Aerts; Henrik Kaessmann
err分享
err收藏
Preclinical drug screen identifies WEE1 inhibitor and vinca alkaloid as a combination treatment concept for Li-Fraumeni syndrome medulloblastoma
erriScience
IF4.1
err2025-12-29
err0
errOAAI
errAnna S. Kolodziejczak; Florian Selt; Heike Peterziel; Nora Jamaladdin; Norman Mack; Kendra Maaß; Chris Meulenbroeks; Romain Sigaud; Christel Herold-Mende; Ahmed El Damaty; Jürgen Burhenne; Shunya Ohmura; Tim Holland-Letz; Lena M. Kutscher; Aurélie Ernst; Pei-Chi Wei; Thomas G.P. Grünewald; Ina Oehme; Marcel Kool; David T.W. Jones
err分享
err收藏
Investigation of a global mouse methylome atlas reveals subtype-specific copy number alterations in pediatric cancer models全球小鼠甲基化图谱的研究揭示了小儿癌症模型中的亚型特异性拷贝数改变
errNature Genetics
IF29
err2025-12-11
err0
errOAAI
errMelanie Schoof; Tuyu Zheng; Martin Sill; Roland Imle; Alessia Cais; Lea Altendorf; Alicia Fürst; Nina Hofmann; Kati Ernst; Dominik Vonficht; Kenneth Chun-Ho Chan; Tim Holland-Letz; Andreas Postlmayr; Ryo Shiraishi; Wanchen Wang; Alaide Morcavallo; Michael Spohn; Carolin Göbel; Judith Niesen; Levke-Sophie Peter; Franck Bourdeaut; Zhi-Yan Han; Yanxin Pei; Najiba Murad; Fredrik J. Swartling; Jessica Taylor; Monika Yadav; Garrett R. Gibson; Richard J. Gilbertson; Matthias Dottermusch; Rajanya Roy; Kornelius Kerl; Rainer Glass; Jiying Cheng; Martin A. Horstmann; Gerrit Wolters-Eisfeld; Haotian Zhao; Dominik Sturm; Viveka Nand Yadav; Louis Chesler; Simon Haas; William A. Weiss; Paul A. Northcott; Lena M. Kutscher; Ana Guerreiro Stucklin; Olivier Ayrault; Julia E. Neumann; Daisuke Kawauchi; David T. W. Jones; Kristian Pajtler; Ana Banito; Stefan M. Pfister; Ulrich Schüller; Marc Zuckermann
err分享
err收藏
DIVERGENT MEDULLOBLASTOMA CHROMATIN STATES DISCLOSE KDM2B AS A SELECTIVE DEPENDENCY分化型髓母细胞瘤染色质状态揭示KDM2B为选择性依赖
errNEURO-ONCOLOGY
IF13.4
err2025-11-01
err0
errOAAI
errTao, Ran; Erkek-Ozhan, Serap; Xu, Beisi; Matsui, Yurika; Mittal, Priya; Smith, Kyle; Li, Yiran; Gao, Qingsong; Darrow, Emily; Xu, Ruijie; Djekidel, Nadhir; Bajpai, Richa; Kumar, Rahul; Reilly, Colleen; Soliman, Taha; Hadley, Jennifer; Batts, Melissa; Bhanu, Natarajan; Gudenas, Brian; Paul, Leena; Lin, Hong; Lowe, Kim; Kutscher, Lena; Garcia, Benjamin; Pruett-Miller, Shondra; Zhou, Xin; Orr, Brent; Robinson, Giles; Wu, Gang; Korbel, Jan; Peng, Jamy; Pfister, Stefan; Northcott, Paul
err分享
err收藏
Genetic modeling of ELP1-associated Sonic hedgehog medulloblastoma identifies MDM2 as a selective therapeutic targetELP1相关Sonic hedgehog型髓母细胞瘤的遗传建模识别MDM2为选择性治疗靶点
errNEURO-ONCOLOGY
IF13.4
err2025-11-01
err0
PREAI
errAhmad, Shiekh Tanveer; Li, Yiran; Garcia-Lopez, Jesus; Gudenas, Brian; Hadley, Jennifer; Paul, Leena; Wu, Stephanie; Refaat, Alaa; Kojic, Marija; Batts, Melissa; Soliman, Taha; Pitre, Aaron; Arnskotter, Frederik; Zindy, Frederique; Jones, Alun; Twarog, Nathaniel; Mayasundari, Anand; Bianski, Brandon; Tinkle, Christopher; Shirinifard, Abbas; Janke, Laura; Lu, Meifen; Lewis, Sara; Onar-Thomas, Arzu; Pfister, Stefan; Gajjar, Amar; Baker, Suzanne; Roussel, Martine; Rankovic, Zoran; Robinson, Giles; Orr, Brent; Wainwright, Brandon; Shelat, Anang; Waszak, Sebastian; Kutscher, Lena; Lin, Hong; Northcott, Paul
err分享
err收藏
Genetic modeling of ELP1-associated Sonic hedgehog medulloblastoma identifies MDM2 as a selective therapeutic targetELP1相关Sonic hedgehog型髓母细胞瘤的遗传建模鉴定MDM2为选择性治疗靶点
errCancer Cell
IF44.5
err2025-05-15
err0
errOAAI
errShiekh Tanveer Ahmad; Yiran Li; Jesus Garcia-Lopez; Brian L. Gudenas; Jennifer Hadley; Leena Paul; Stephanie C. Wu; Alaa Refaat; Marija Kojic; Melissa Batts; Taha Soliman; Aaron Pitre; Frederik Arnskötter; Frederique Zindy; Alun Jones; Nathaniel R. Twarog; Anand Mayasundari; Brandon Bianski; Christopher Tinkle; Abbas Shirinifard; Laura Janke; Meifen Lu; Sara A. Lewis; Arzu Onar-Thomas; Stefan M. Pfister; Amar Gajjar; Suzanne J. Baker; Martine F. Roussel; Zoran Rankovic; Giles W. Robinson; Brent A. Orr; Brandon Wainwright; Anang A. Shelat; Sebastian M. Waszak; Lena M. Kutscher; Hong Lin; Paul A. Northcott
err分享
err收藏
GERMLINEELP1 DEFICIENCY SENSITIZES CEREBELLAR GRANULE NEURON PROGENITORS TO SHH MEDULLOBLASTOMA
errNEURO-ONCOLOGY
IF13.4
err2024-11-11
err0
PREAI
errTanveer Ahmad, Shiekh; Garcia-Lopez, Jesus; Li, Yiran; Hadley, Jennifer; Paul, Leena; Gudenas, Brian; Batts, Melissa; Soliman, Taha; Pitre, Aaron; Kojic, Marija; Manz, Frederik; Zindy, Frederique; Jones, Alun; Mayasundari, Anand; Bianski, Brandon; Tinkle, Christopher; Shirinifard, Abbas; Janke, Laura Janke; Lu, Meifen; Onar-Thomas, Arzu; Pfister, Stefan; Gajjar, Amar; Baker, Suzanne; Roussel, Martine; Rankovic, Zoran; Robinson, Giles; Orr, Brent; Wainwright, Brandon; Kutscher, Lena; Waszak, Sebastian; Lin, Hong; Northcott, Paul
err分享
err收藏
Loss of Elp1 in cerebellar granule cell progenitors models ataxia phenotype of Familial Dysautonomia
errNEUROBIOLOGY OF DISEASE
IF5.6
err2024-09-01
err0
errOAAI
errArnskoetter, Frederik; da Silva, Patricia Benites Goncalves; Schouw, Mackenna E.; Lukasch, Chiara; Bianchini, Luca; Sieber, Laura; Garcia-Lopez, Jesus; Ahmad, Shiekh Tanveer; Li, Yiran; Lin, Hong; Joshi, Piyush; Spaenig, Lisa; Rados, Magdalena; Roiuk, Mykola; Sepp, Mari; Zuckermann, Marc; Northcott, Paul A.; Patrizi, Annarita; Kutscher, Lena M.
err分享
err收藏
DIVERGENT MEDULLOBLASTOMA CHROMATIN STATES DISCLOSE KDM2B AS A NOVEL ONCOGENIC DEPENDENCY
errNEURO-ONCOLOGY
IF13.4
err2024-06-18
err0
errOAAI
errTao, Ran; Erkek, Serap; Matsui, Yurika; Xu, Beisi; Smith, Kyle S.; Gao, Qingsong; Li, Yiran; Djekidel, Nadhir; Darrow, Emily; Kumar, Rahul; Paul, Leena; Lin, Hong; Hadley, Jennifer; Batts, Melissa; Bhanu, Natarajan, V; Kutscher, Lena; Garcia, Benjamin A.; Zhou, Xin; Orr, Brent A.; Robinson, Giles W.; Wu, Gang; Korbel, Jan O.; Peng, Jamy; Pfister, Stefan M.; Northcott, Paul A.
err分享
err收藏
COMPARING THE RADIOSENSITIZATION POTENTIAL OF VARIOUS COMPOUND CLASSES IN PEDIATRIC-TYPE DIFFUSE HIGH-GRADE GLIOMA
errNEURO-ONCOLOGY
IF13.4
err2024-06-18
err0
errOAAI
errCais, Alessia; Lipiec, Szymon; Chan, Kenneth Chun-Ho; Hofmann, Nina; Gade, Clara; von Soosten, Laura; Imle, Roland; Roscher, Mareike; Euler-Lange, Rosemarie; Zheng, Tuyu; Manz, Frederik; Kutscher, Lena M.; Pajtler, Kristian W.; Peterziel, Heike; Oehme, Ina; Witt, Olaf; Kurth, Ina; Jones, David T. W.; Pfister, Stefan M.; Zuckermann, Marc
err分享
err收藏
GERMLINEELP1 DEFICIENCY SENSITIZES CEREBELLAR GRANULE NEURON PROGENITORS TO SHH MEDULLOBLASTOMA
errNEURO-ONCOLOGY
IF13.4
err2024-06-18
err0
errOAAI
errAhmad, Shiekh Tanveer; Garcia-Lopez, Jesus; Li, Yiran; Gudenas, Brian; Hadley, Jennifer; Paul, Leena; Batts, Melissa; Soliman, Taha; Kojic, Marija; Pitre, Aaron; Manz, Frederik; Zindy, Frederique; Jones, Alun; Mayasundari, Anand; Bianski, Brandon; Tinkle, Christopher; Shirinifard, Abbas; Janke, Laura; Lu, Meifen; Pfister, Stefan M.; Gajjar, Amar; Baker, Suzanne J.; Roussel, Martine F.; Rankovic, Zoran; Waszak, Sebastian M.; Robinson, Giles W.; Orr, Brent A.; Wainwright, Brandon; Kutscher, Lena M.; Lin, Hong; Northcott, Paul A.
err分享
err收藏
ESTABLISHING A NOVEL CEREBELLAR ORGANOID MODEL FOR INVESTIGATING HEREDITARY PREDISPOSITION TO CHILDHOOD BRAIN CANCER
errNEURO-ONCOLOGY
IF13.4
err2024-06-18
err0
errOAAI
errManz, Frederik; Bianchini, Luca; Atamian, Alexander; Northcott, Paul; Quadrato, Giorgia; Kutscher, Lena
err分享
err收藏
GENE REGULATORY NETWORK LANDSCAPE OF GROUP 3/4 MEDULLOBLASTOMA
errNEURO-ONCOLOGY
IF13.4
err2024-06-18
err0
errOAAI
errJoshi, Piyush; Stelzer, Tamina; Okonechnikov, Konstantin; Sarropoulos, Ioannis; Sepp, Mari; Pour-Jamnani, Mischan, V; Rademacher, Anne; Yamada-Saito, Tetsuya; Schneider, Celine; Schmidt, Julia; Schaefer, Philipp; Leiss, Kevin; Bortolomeazzi, Michele; Mallm, Jan-Philipp; da Silva, Patricia B. G.; Statz, Britta; Wittmann, Andrea; Schramm, Kathrin; Blattner-Johnson, Mirjam; Fiesel, Petra; Jones, Barbara; Milde, Till; Pajtler, Kristian; van Tilburg, Cornelis M.; Witt, Olaf; Rippe, Karsten; Korshunov, Andrey; Jones, David T. W.; Hovestadt, Volker; Northcott, Paul A.; Thongjuea, Supat; Jaeger, Natalie; Kaessmann, Henrik; Pfister, Stefan M.; Kutscher, Lena M.
err分享
err收藏
OVEREXPRESSION OF THE PLAG-GENE FAMILY MEMBER PLAG1 DURING MURINE BRAIN DEVELOPMENT LEADS TO ABERRANT EXPRESSION OF IMPRINTED GENES AND THE FORMATION OF MIDLINE BRAIN TUMORS
errNEURO-ONCOLOGY
IF13.4
err2024-06-18
err0
errOAAI
errVaillant, Jan; Keck, Michaela-Kristina; Wittmann, Andrea; Hofmann, Nina; Sievers, Philipp; Chen, Angela; Rozowsky, Jacob S.; Filbin, Mariella G.; Beroukhim, Rameen; Bandopadhahay, Pratiti; Jones, David T. W.; Kutscher, Lena M.
err分享
err收藏
SOLID PEDIATRIC TUMORS IN MICE REVEAL MODEL-SPECIFIC GLOBAL DNA METHYLATION AND CNV PROFILES CORRESPONDING TO HUMAN COUNTERPARTS
errNEURO-ONCOLOGY
IF13.4
err2024-06-18
err0
errOAAI
errSchoof, Melanie; Zheng, Tuyu; Sill, Martin; Imle, Roland; Hofmann, Nina; Ernst, Kati; Vonficht, Dominik; Chan, Chun Ho; Cais, Alessia; Holland-Letz, Tim; Postlmayr, Andreas; Shiraishi, Ryo; Wang, Wanchen; Morcavallo, Alaide; Spohn, Michael; Goebel, Carolin; Niesen, Judith; Peter, Levke-Sophie; Eckhardt, Alicia; Bourdeaut, Franck; Han, Zhi-Yan; Pei, Yanxin; Murad, Najiba; Swartling, Fredrik J.; Taylor, Jessica; Gilbertson, Richard J.; Dottermusch, Matthias; Kerl, Kornelius; Glass, Rainer; Cheng, Jiying; Horstmann, Martin A.; Nollau, Peter; Wolters-Eisfeld, Gerrit; Zhao, Haotian; Sturm, Dominik; Chesler, Louis; Haas, Simon; Weiss, William A.; Northcott, Paul A.; Kutscher, Lena M.; Stuecklin, Ana Guerreiro; Ayrault, Olivier; Neumann, Julia E.; Kawauchi, Daisuke; Jones, David; Pfister, Stefan M.; Pajtler, Kristian; Banito, Ana; Schueller, Ulrich; Zuckermann, Marc
err分享
err收藏
The Virtual Child虚拟的孩子
errCANCER DISCOVERY
IF33.3
err2024-04-04
err1
errOAAI
errGilbertson, Richard J.; Behjati, Sam; Boettcher, Anna-Lisa; Bronner, Marianne E.; Burridge, Matthew; Clausing, Henrick; Clifford, Harry; Danaher, Tracey; Donovan, Laura K.; Drost, Jarno; Eggermont, Alexander M. M.; Emerson, Chris; Flores, Mona G.; Hamerlik, Petra; Jabado, Nada; Jones, Andrew; Kaessmann, Henrick; Kleinman, Claudia L.; Kool, Marcel; Kutscher, Lena M.; Lindberg, Gavin; Linnane, Emily; Marioni, John C.; Maris, John M.; Monje, Michelle; Macaskill, Alexandra; Niederer, Steven; Northcott, Paul A.; Peeters, Elizabeth; Plieger-van Solkema, Willemijn; Preussner, Liane; Rios, Anne C.; Rippe, Karsten; Sandford, Peter; Sgourakis, Nikolaos G.; Shlien, Adam; Smith, Pete; Straathof, Karin; Sullivan, Patrick J.; Suva, Mario L.; Taylor, Michael D.; Thompson, Emma; Vento-Tormo, Roser; Wainwright, Brandon J.; Wechsler-Reya, Robert J.; Westermann, Frank; Winslade, Shannon; Al-Lazikani, Bissan; Pfister, Stefan M.
err分享
err收藏
Mapping pediatric brain tumors to their origins in the developing cerebellum将小儿脑肿瘤映射到发育中的小脑的起源
errNEURO-ONCOLOGY
IF13.4
err2023-08-03
err12
errOAAI
errOkonechnikov, Konstantin; Joshi, Piyush; Sepp, Mari; Leiss, Kevin; Sarropoulos, Ioannis; Murat, Florent; Sill, Martin; Beck, Pengbo; Chan, Kenneth Chun-Ho; Korshunov, Andrey; Sah, Felix; Deng, Maximilian Y.; Sturm, Dominik; DeSisto, John; Donson, Andrew M.; Foreman, Nicholas K.; Green, Adam L.; Robinson, Giles; Orr, Brent A.; Gao, Qingsong; Darrow, Emily; Hadley, Jennifer L.; Northcott, Paul A.; Gojo, Johannes; Kawauchi, Daisuke; Hovestadt, Volker; Filbin, Mariella G.; von Deimling, Andreas; Zuckermann, Marc; Pajtler, Kristian W.; Kool, Marcel; Jones, David T. W.; Jaeger, Natalie; Kutscher, Lena M.; Kaessmann, Henrik; Pfister, Stefan M.
err分享
err收藏
Modeling brain and neural crest neoplasms with human pluripotent stem cells
errNEURO-ONCOLOGY
IF13.4
err2023-02-09
err3
errOAAI
errSchloo, Cedar; Kutscher, Lena M.
err分享
err收藏

研究方向

暂时未获取到该数据
合作学者
合作期刊
A
Andreas von Deimling
H 指数: 175 · 论文数: 1.8K
S
Svante Pääbo
H 指数: 160 · 论文数: 470
S
Stefan M. Pfister
H 指数: 159 · 论文数: 2.1K
P
Peter Lichter
H 指数: 146 · 论文数: 1.0K
D
David Jones
H 指数: 144 · 论文数: 1.5K
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