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M

Michael P. Murphy

MRC Mitochondrial Biology Unit
H指数:142
被引数:8.2万

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The Batten disease protein CLN8 is a stereospecific acyltransferase in bis(monoacylglycero)phosphate biosynthesis

Batten病蛋白CLN8是二(单酰甘油)磷酸生物合成中的立体特异性酰基转移酶

Nature Cell Biology
IF19.1
2026-09-150
OA
Pradeep K. Sheokand; Denis Lacabanne; Andrew M. James; Stefania Della Vecchia; Jonathan J. Ruprecht; Joris van der Kleij; Keira Turner; Jessica Müller-Niva; Miia H. Salo; Benjamin Jenkins; Susannah K. Leese; Nidhi Juneja; Chak Shun Yu; Clarissa D. Booth; Martin S. King; Johanna Uusimaa; Jill M. Weimer; Albert Koulman; Reetta Hinttala; Filippo M. Santorelli; Maria Marchese; Michael P. Murphy; Edmund R. S. Kunji; Kasparas Petkevicius
Tumor-derived antioxidants suppress immunity by depriving T cells of reactive oxygen species

肿瘤源性抗氧化剂通过剥夺T细胞的活性氧来抑制免疫

Science
IF45.8
2026-09-030
PRE
Alexander J. Wesolowski; Ardon M. Pillay; Panagiota Vardaka; Rabab Nasrallah; Randy Greaves; Housaiyin Li; Iliana Loffreda; Chelsea Jenkin; Andrew M. James; Alica Nübling; Christopher J. Ward; Teresa von Linde; Alberto G. Conti; Sheue-Fen Tzeng; Layla Dahmani; Alexander C. Evans; Sarah K. Whiteside; Yumi Yamashita-Kanemaru; Charlotte J. Imianowski; Jie Yang; Ignacio Moraga Gonzalez; Jack Chapman; Aws Al-Deka; Klaus Okkenhaug; Michael P. Murphy; Bartlomiej Swiatczak; Geoffrey Guittard; Enrico Lugli; Lukas Flatz; Ping-Chih Ho; Robert L. Eil; Rahul Roychoudhuri
Protein thiol alterations drive pathologic liquid–liquid phase separation in the aging brain

蛋白质巯基改变驱动老年大脑中的病理性液-液相分离

NATURE STRUCTURAL & MOLECULAR BIOLOGY
IF10.1
2026-07-300
OA
Thibaut Vignane; Martín Hugo; Christian Hoffmann; Polina Reichert; Antonia Katsouda; Davide D’Andrea; Han Wang; Johannes V. Tromm; Marko Miler; Ferran Comas; Dunja Petrovic; Suyuan Chen; Jan Lj. Miljkovic; Danail Stoychev; Erik Lacko; Vladimir M. Jovanovic; Suwarna Chakraborty; Sunil J. Tripathi; Edwin Vázquez-Rosa; Jordan L. Morris; Suvagata Roy Chowdhury; Julien Prudent; Albert Sickmann; Natalija Polovic; Andrew A. Pieper; Ilan Davis; Kostas Tokatlidis; Bindu D. Paul; Michael P. Murphy; Christian Münch; Andreas Papapetropoulos; Dragomir Milovanovic; Milos R. Filipovic
Targeting immunometabolic pathways with AZD1656 alleviates inflammation and metabolic dysfunction in type 2 diabetic cardiomyopathy

AZD1656靶向免疫代谢通路可缓解2型糖尿病心肌病中的炎症和代谢功能障碍

Nature Cardiovascular Research
IF10.8
2026-02-230
OAAI
Stephanie Anderson; Anja Karlstaedt; Megan Young; Loucia Karatzia; Fenn Cullen; Jianmin Chen; Caroline E. O’Riordan; Michael R. Barnes; Zorana Štaka; Lauren J. Albee; Conor Garrod-Ketchley; Sanushi Dambure; Hiran A. Prag; Filip Cvetko; Jack J. J. J. Miller; Christoph Thiemermann; Andrew J. M. Lewis; Michael P. Murphy; David M. Smith; Sian M. Henson; Damian J. Tyler; Dunja Aksentijevic
Defective vascular smooth muscle cell tafazzin impairs mitochondrial function and promotes atherosclerosis in preclinical models

缺陷性血管平滑肌细胞tafazzin损害线粒体功能并促进前临床模型中的动脉粥样硬化

Nature Communications
IF15.7
2025-12-040
OAAI
Cindy Dong; Alison Finigan; Nichola Figg; Benjamin Jenkins; Albert Koulman; Suvagata R. Chowdhury; Anne-Marie Tricolici; Jordi Lambert; Sebnem Oc; Helle F. Jørgensen; Julien Prudent; Michael P. Murphy; Martin Bennett; Emma Yu
Simultaneous and sensitive quantification of protein and low molecular weight persulfides, polysulfides and H2S in biological samples

同时灵敏地定量生物样品中的蛋白质和低分子量过硫化物，多硫化物和H2S

Nature Communications
IF15.7
2025-12-040
OAAI
Jan Lj. Miljkovic; Nils Burger; Chak Shun Yu; Alexander H. Harkiss; Stefan Warrington; Stuart T. Caldwell; Scott A. Jones; Jordan J. Lee; Dunja Aksentijevic; Andrew M. James; Thomas Krieg; Richard C. Hartley; Michael P. Murphy
Impact of Prophylactic Total Gastrectomy (PTG) on Long-Term Health-Related Quality of Life in Patients with Hereditary Diffuse Gastric Cancer

预防性全胃切除术(PTG)对遗传性弥漫性胃癌患者长期健康相关生活质量的影响

BJS-BRITISH JOURNAL OF SURGERY
IF0
2025-12-010
PRE
Lim, Hui Jun; O'Donovan, Maria; Samra, Sophie; Lamb, Claire; Chinyama, Nyarai; Fletcher, Paul; Ziauddeen, Hisham; Murphy, Patrick; Tai, Ju Yi; di Pietro, Massimiliano; Fitzgerald, Rebecca; O'Neill, J. Robert
Innate immune and metabolic signals induce mitochondria-dependent membrane lysis via mitoxyperiosis

固有免疫和代谢信号通过溶线粒体作用诱导线粒体依赖的膜裂解。

Cell
IF42.5
2025-11-280
PRE
Yaqiu Wang; Jianlin Lu; Alexandre F. Carisey; Sangappa B. Chadchan; Ha Won Lee; R.K. Subbarao Malireddi; Bhesh Raj Sharma; Nagakannan Pandian; Rebecca E. Tweedell; Gustavo Palacios; Nathalie Becerra Mora; Camenzind G. Robinson; Aaron Pitre; Peter Vogel; Taosheng Chen; Michael P. Murphy; Thirumala-Devi Kanneganti
An inherited mitochondrial DNA mutation remodels inflammatory cytokine responses in macrophages and in vivo in mice

一种遗传性线粒体DNA突变重塑了巨噬细胞和小鼠体内的促炎细胞因子反应。

Nature Communications
IF15.7
2025-11-200
OAAI
Eloïse Marques; Stephen P. Burr; Alva M. Casey; Richard J. Stopforth; Chak Shun Yu; Keira Turner; Dane M. Wolf; Marisa Dilucca; Vincent Paupe; Suvagata Roy Chowdhury; Victoria J. Tyrrell; Robbin Kramer; Yamini M. Kanse; Chinmayi Pednekar; Chris A. Powell; James B. Stewart; Julien Prudent; Michael P. Murphy; Michal Minczuk; Valerie B. O’Donnell; Clare E. Bryant; Patrick F. Chinnery; Arthur Kaser; Alexander von Kriegsheim; Dylan G. Ryan
A double-blind, randomized placebo-controlled trial examining the effect of MitoQ on myocardial energetics in patients with dilated cardiomyopathy

一项双盲、随机安慰剂对照试验，旨在研究MitoQ对扩张型心肌病患心肌能量代谢的影响。

EUROPEAN HEART JOURNAL-CARDIOVASCULAR IMAGING
IF6.6
2025-11-010
OAAI
Halliday, Brian P.; Owen, Ruth; Ragavan, Aaraby; Smith, Katherine L.; Statton, Ben; Berry, Alaine; Kasiakogias, Alex; Tsoumani, Zoi; Shanmuganathan, Mayooran; Dungu, Jason N.; De Marvao, Antonio; Tayal, Upasana; Ware, James S.; O'regan, Declan P.; Pennell, Dudley J.; Cleland, John G. F.; Prasad, Sanjay K.; Gregson, John; Murphy, Michael P.; Rider, Oliver J.; Valkovic, Ladislav
H3G34-MUTANT DIFFUSE HEMISPHERIC GLIOMAS CONTAIN CELLULAR NICHES OF GABAERGIC INTERNEURON-LIKE CELLS WITH DUAL FREQUENCY AUTONOMOUS RHYTHMIC CALCIUM ACTIVITY

H3G34-突变弥漫性半球胶质瘤包含具有双频自主节律性钙活动的γ-氨基丁酸能中间神经元样细胞的细胞微环境

NEURO-ONCOLOGY
IF13.4
2025-11-010
OAAI
Cruzeiro, Gustavo Alencastro Veiga; Buhse, Johann; Cascio, Costanza Lo; Neyazi, Sina; Katiyar, Shashank; Tabatabai, Kuscha; Taylor, Kathryn; De Biagi Jr, Carlos Alberto Oliveira; Haase, Rebecca; Sarwnow, Katharina; Venkataramani, Varun; Liu, Ilon; Huang, Kun; Murphy, Maria Pazyra; Schuller, Ulrich; Segal, Rosalind; Tang, Xin; Monje, Michelle; Filbin, Mariella
Chronic Sleep Fragmentation Differentially Affects Alzheimer’s Disease Pathology in Male and Female APPSAA Knock-in Mice

慢性睡眠片段化对雄性和雌性APP<sup>SAA</sup>基因敲入小鼠的阿尔茨海默病病理产生差异性影响

Journal of Inflammation Research
IF4.1
2025-10-160
OAAI
Margaret R Hawkins; Haleigh R Whitlock; Carrie E Johnson; Teresa Macheda; MaKayla F Cox; Madison G Lapid; Kelly N Roberts; Heather M Hash; Esther G Drinkard; Sridhar Sunderam; Bruce F O’Hara; Michael P Murphy; Marilyn J Duncan; Adam D Bachstetter
Enhancing autophagy by redox regulation extends lifespan in Drosophila

通过氧化还原调控增强自噬可延长果蝇寿命

Nature Communications
IF15.7
2025-06-250
OAAI
Claudia Lennicke; Ivana Bjedov; Sebastian Grönke; Katja E. Menger; Andrew M. James; Jorge Iván Castillo-Quan; Lucie A. G. van Leeuwen; Andrea Foley; Marcela Buricova; Jennifer Adcott; Alex Montoya; Holger B. Kramer; Pavel V. Shliaha; Angela Logan; Filipe Cabreiro; Michael P. Murphy; Linda Partridge; Helena M. Cochemé

研究方向

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R
Robin A.J. Smith
H 指数:62论文数:257被引数:1.8万
A
Angela Logan
H 指数:47论文数:82被引数:1.1万
T
Thomas Krieg
H 指数:54论文数:230被引数:1.2万
A
Andrew M. James
H 指数:0论文数:4被引数:29
R
Richard C. Hartley
H 指数:46论文数:207被引数:1.2万
T
Tracy A. Prime
H 指数:35论文数:82被引数:4,423
H
Hiran A. Prag
H 指数:25论文数:69被引数:4,423
H
Helena M. Cochemé
H 指数:35论文数:54被引数:8,587
S
Stuart T. Caldwell
H 指数:25论文数:89被引数:3,914
A
Andrew M. James
H 指数:52论文数:160被引数:1.3万