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Z

Zacary P. Germon

University of Newcastle
H指数:9
被引数:449

个人简介

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教育背景

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工作经历

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荣誉奖项

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Precision Targeting of PI3K/mTOR in Diffuse Midline Glioma: GCT007 as a Novel Brain-Penetrant PIK3CA Inhibitor

弥漫性中线胶质瘤中PI3K/mTOR的精确靶向：GCT007作为新型脑穿透性PIK3CA抑制剂

NEURO-ONCOLOGY
IF13.4
2025-11-010
OAAI
Jackson, Evangeline; Duchatel, Ryan; Vo, Tuan; Savary, Clara; Germon, Zacary; Riley, Madisen; McEwen, Holly; Persson, Mika; Findlay, Izac; Beitaki, Tyrone; Lally, Marissa; Douglas, Alicia; Rogers, M. Karen Newell; Fonkem, Ekokobe; Franson, Andrea; Kline, Cassie; Nazarian, Javad; Koschmann, Carl; Mueller, Sabine; Dun, Matthew
PI3K/mTOR is a therapeutically targetable genetic dependency in diffuse intrinsic pontine glioma
JOURNAL OF CLINICAL INVESTIGATION
IF13.6
2024-02-068
OAAI
Duchatel, Ryan J.; Jackson, Evangeline R.; Parackal, Sarah G.; Kiltschewskij, Dylan; Findlay, Izac J.; Mannan, Abdul; Staudt, Dilana E.; Thomas, Bryce C.; Germon, Zacary P.; Laternser, Sandra; Kearney, Padraic S.; Jamaluddin, M. Fairuz B.; Douglas, Alicia M.; Beitaki, Tyrone; McEwen, Holly P.; Persson, Mika L.; Hocke, Emily A.; Jain, Vaibhav; Aksu, Michael; Manning, Elizabeth E.; Murray, Heather C.; Verrills, Nicole M.; Sun, Claire Xin; Daniel, Paul; Vilain, Ricardo E.; Skerrett-Byrne, David A.; Nixon, Brett; Hua, Susan; de Bock, Charles E.; Colino-Sanguino, Yolanda; Valdes-Mora, Fatima; Tsoli, Maria; Ziegler, David S.; Cairns, Murray J.; Raabe, Eric H.; Vitanza, Nicholas A.; Hulleman, Esther; Phoenix, Timothy N.; Koschmann, Carl; Alvaro, Frank; Dayas, Christopher, V; Tinkle, Christopher L.; Wheeler, Helen; Whittle, James R.; Eisenstat, David D.; Firestein, Ron; Mueller, Sabine; Valvi, Santosh; Hansford, Jordan R.; Ashley, David M.; Gregory, Simon G.; Kilburn, Lindsay B.; Nazarian, Javad; Cain, Jason E.; Dun, Matthew D.
ONC201 in Combination with Paxalisib for the Treatment of H3K27-Altered Diffuse Midline Glioma
CANCER RESEARCH
IF16.6
2023-05-0530
OAAI
Jackson, Evangeline R.; Duchatel, Ryan J.; Staudt, Dilana E.; Persson, Mika L.; Mannan, Abdul; Yadavilli, Sridevi; Parackal, Sarah; Game, Shaye; Chong, Wai Chin; Jayasekara, W. Samantha N.; Le Grand, Marion; Kearney, Padraic S.; Douglas, Alicia M.; Findlay, Izac J.; Germon, Zacary P.; McEwen, Holly P.; Beitaki, Tyrone S.; Patabendige, Adjanie; Skerrett-Byrne, David A.; Nixon, Brett; Smith, Nathan D.; Day, Bryan; Manoharan, Neevika; Nagabushan, Sumanth; Hansford, Jordan R.; Govender, Dinisha; McCowage, Geoff B.; Firestein, Ron; Howlett, Meegan; Endersby, Raelene; Gottardo, Nicholas G.; Alvaro, Frank; Waszak, Sebastian M.; Larsen, Martin R.; Colino-Sanguino, Yolanda; Valdes-Mora, Fatima; Rakotomalala, Andria; Meignan, Samuel; Pasquier, Eddy; Andre, Nicolas; Hulleman, Esther; Eisenstat, David D.; Vitanza, Nicholas A.; Nazarian, Javad; Koschmann, Carl; Mueller, Sabine; Cain, Jason E.; Dun, Matthew D.
Blockade of ROS production inhibits oncogenic signaling in acute myeloid leukemia and amplifies response to precision therapies
SCIENCE SIGNALING
IF6.6
2023-03-2811
PRE
Germon, Zacary P.; Sillar, Jonathan R.; Mannan, Abdul; Duchatel, Ryan J.; Staudt, Dilana; Murray, Heather C.; Findlay, Izac J.; Jackson, Evangeline R.; McEwen, Holly P.; Douglas, Alicia M.; McLachlan, Tabitha; Schjenken, John E.; Skerrett-Byrne, David A.; Huang, Honggang; Melo-Braga, Marcella N.; Plank, Maximilian W.; Alvaro, Frank; Chamberlain, Janis; De Iuliis, Geoff; Aitken, R. John; Nixon, Brett; Wei, Andrew H.; Enjeti, Anoop K.; Huang, Yizhou; Lock, Richard B.; Larsen, Martin R.; Lee, Heather; Vaghjiani, Vijesh; Cain, Jason E.; de Bock, Charles E.; Verrills, Nicole M.; Dun, Matthew D.
Preclinical and clinical evaluation of German-sourced ONC201 for the treatment of H3K27M-mutant diffuse intrinsic pontine glioma

德国来源的ONC201治疗H3K27M-mutant弥漫性内源性桥脑胶质瘤的临床前评估和临床评估

NEURO-ONCOLOGY ADVANCES
IF4.1
2021-11-1931
OAAI
Duchatel, Ryan J.; Mannan, Abdul; Woldu, Ameha S.; Hawtrey, Tom; Hindley, Phoebe A.; Douglas, Alicia M.; Jackson, Evangeline R.; Findlay, Izac J.; Germon, Zacary P.; Staudt, Dilana; Keamey, Padraic S.; Smith, Nathan D.; Hindley, Kate E.; Cain, Jason E.; Andre, Nicolas; La Madrid, Andres Morales; Nixon, Brett; De Luliis, Geoffry N.; Nazarian, Javad; Irish, Kathleen; Alvaro, Frank; Eisenstat, David D.; Beck, Alexander; Vitanza, Nicholas A.; Mueller, Sabine; Morris, Jonathan C.; Dun, Matthew D.
Shwachman-Bodian-Diamond syndrome (SBDS) protein is a direct inhibitor of protein phosphatase 2A (PP2A) activity and overexpressed in acute myeloid leukaemia
LEUKEMIA
IF13.4
2020-04-0813
OAAI
Dun, Matthew D.; Mannan, Abdul; Rigby, Callum J.; Butler, Stephen; Toop, Hamish D.; Beck, Dominik; Connerty, Patrick; Sillar, Jonathan; Kahl, Richard G. S.; Duchatel, Ryan J.; Germon, Zacary; Faulkner, Sam; Chi, Mengna; Skerrett-Byrne, David; Murray, Heather C.; Flanagan, Hayley; Almazi, Juhura G.; Hondermarck, Hubert; Nixon, Brett; De Iuliis, Geoff; Chamberlain, Janis; Alvaro, Frank; de Bock, Charles E.; Morris, Jonathan C.; Enjeti, Anoop K.; Verrills, Nicole M.

研究方向

暂未获取到该数据
M
Matthew D. Dun
H 指数:41论文数:327被引数:5,343
A
Abdul Mannan
H 指数:15论文数:117被引数:664
E
Evangeline R. Jackson
H 指数:10论文数:64被引数:476
R
Ryan J. Duchatel
H 指数:16论文数:174被引数:830
I
Izac J. Findlay
H 指数:9论文数:55被引数:563
A
Alicia M. Douglas
H 指数:9论文数:53被引数:446
B
Brett Nixon
H 指数:58论文数:302被引数:1.1万
F
Frank Alvaro
H 指数:27论文数:119被引数:2,741
M
Mika L. Persson
H 指数:6论文数:42被引数:304
D
Dilana E. Staudt
H 指数:11论文数:49被引数:515