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Changes in iPSC-astrocyte morphology reflect Alzheimer's disease patient clinical markers Rowland, Helen A.; Miller, Georgina; Liu, Qiang; Li, Shuhan; Sharp, Nicola R.; Ng, Bryan; Wei, Tina; Arunasalam, Kanisa; Koychev, Ivan; Hedegaard, Anne; Ribe, Elena M.; Chan, Dennis; Chessell, Tharani; Kocagoncu, Ece; Lawson, Jennifer; Malhotra, Paresh; Ridha, Basil H.; Rowe, James B.; Thomas, Alan J.; Zamboni, Giovanna; Zetterberg, Henrik; Cader, M. Zameel; Wade-Martins, Richard; Lovestone, Simon; Nevado-Holgado, Alejo; Kormilitzin, Andrey; Buckley, Noel J. 分享 收藏
SRRM4-mediated REST to REST4 dysregulation promotes tumor growth and neural adaptation in breast cancer leading to brain metastasis Deshpande, Krutika; Martirosian, Vahan; Nakamura, Brooke N.; Das, Diganta; Iyer, Mukund; Reed, Max; Shao, Ling; Bamshad, Daniella; Buckley, Noel J.; Neman, Josh 分享 收藏
Proteomics analysis of plasma from middle-aged adults identifies protein markers of dementia risk in later life 中年人血浆蛋白质组学分析鉴定晚年痴呆风险的蛋白质标志物 Walker, Keenan A.; Chen, Jingsha; Shi, Liu; Yang, Yunju; Fornage, Myriam; Zhou, Linda; Schlosser, Pascal; Surapaneni, Aditya; Grams, Morgan E.; Duggan, Michael R.; Peng, Zhongsheng; Gomez, Gabriela T.; Tin, Adrienne; Hoogeveen, Ron C.; Sullivan, Kevin J.; Ganz, Peter; Lindbohm, Joni V.; Kivimaki, Mika; Nevado-Holgado, Alejo J.; Buckley, Noel; Gottesman, Rebecca F.; Mosley, Thomas H.; Boerwinkle, Eric; Ballantyne, Christie M.; Coresh, Josef 分享 收藏
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Multiomics profiling of human plasma and cerebrospinal fluid reveals ATN-derived networks and highlights causal links in Alzheimer's disease Shi, Liu; Xu, Jin; Green, Rebecca; Wretlind, Asger; Homann, Jan; Buckley, Noel J.; Tijms, Betty M.; Vos, Stephanie J. B.; Lill, Christina M.; ten Kate, Mara; Engelborghs, Sebastiaan; Sleegers, Kristel; Frisoni, Giovanni B.; Wallin, Anders; Lleo, Alberto; Popp, Julius; Martinez-Lage, Pablo; Streffer, Johannes; Barkhof, Frederik; Zetterberg, Henrik; Visser, Pieter Jelle; Lovestone, Simon; Bertram, Lars; Nevado-Holgado, Alejo J.; Proitsi, Petroula; Legido-Quigley, Cristina 分享 收藏
Predicting AT(N) pathologies in Alzheimer's disease from blood-based proteomic data using neural networks Zhang, Yuting; Ghose, Upamanyu; Buckley, Noel J.; Engelborghs, Sebastiaan; Sleegers, Kristel; Frisoni, Giovanni B.; Wallin, Anders; Lleo, Alberto; Popp, Julius; Martinez-Lage, Pablo; Legido-Quigley, Cristina; Barkhof, Frederik; Zetterberg, Henrik; Visser, Pieter Jelle; Bertram, Lars; Lovestone, Simon; Nevado-Holgado, Alejo J.; Shi, Liu 分享 收藏
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Neurons derived from individual early Alzheimer's disease patients reflect their clinical vulnerability Ng, Bryan; Rowland, Helen A.; Wei, Tina; Arunasalam, Kanisa; Hayes, Emma Mee; Koychev, Ivan; Hedegaard, Anne; Ribe, Elena M.; Chan, Dennis; Chessell, Tharani; Ffytche, Dominic; Gunn, Roger N.; Kocagoncu, Ece; Lawson, Jennifer; Malhotra, Paresh A.; Ridha, Basil H.; Rowe, James B.; Thomas, Alan J.; Zamboni, Giovanna; Buckley, Noel J.; Cader, Zameel M.; Lovestone, Simon; Wade-Martins, Richard 分享 收藏
Repressor element 1-silencing transcription factor deficiency yields profound hearing loss through Kv7.4 channel upsurge in auditory neurons and hair cells Zhang, Haiwei; Li, Hongchen; Lu, Mingshun; Wang, Shengnan; Ma, Xueya; Wang, Fei; Liu, Jiaxi; Li, Xinyu; Yang, Haichao; Zhang, Fan; Shen, Haitao; Buckley, Noel J.; Gamper, Nikita; Yamoah, Ebenezer N.; Lv, Ping 分享 收藏
Identification of plasma proteins relating to brain neurodegeneration and vascular pathology in cognitively normal individuals Shi, Liu; Buchanan, Colin R.; Cox, Simon R.; Hillary, Robert F.; Marioni, Riccardo E.; Campbell, Archie; Hayward, Caroline; Stolicyn, Aleks; Whalley, Heather C.; Harris, Mathew A.; Waymont, Jennifer; Waiter, Gordon; Backhouse, Ellen; Wardlaw, Joanna M.; Steele, Douglas; Mcintosh, Andrew; Lovestone, Simon; Buckley, Noel J.; Nevado-Holgado, Alejo J. 分享 收藏
Plasma Proteomic Biomarkers Relating to Alzheimer's Disease: A Meta-Analysis Based on Our Own Studies 与阿尔茨海默病相关的血浆蛋白质组生物标志物: 基于我们自己研究的荟萃分析 Shi, Liu; Buckley, Noel J. J.; Bos, Isabelle; Engelborghs, Sebastiaan; Sleegers, Kristel; Frisoni, Giovanni B.; Wallin, Anders; Lleo, Alberto; Popp, Julius; Martinez-Lage, Pablo; Legido-Quigley, Cristina; Barkhof, Frederik; Zetterberg, Henrik; Visser, Pieter Jelle; Bertram, Lars; Lovestone, Simon; Nevado-Holgado, Alejo J. 分享 收藏
High Blood Pressure and Risk of Dementia: A Two-Sample Mendelian Randomization Study in the UK Biobank Sproviero, William; Winchester, Laura; Newby, Danielle; Fernandes, Marco; Shi, Liu; Goodday, Sarah M.; Prats-Uribe, Albert; Alhambra, Daniel P.; Buckley, Noel J.; Nevado-Holgado, Alejo J. 分享 收藏
Replication study of plasma proteins relating to Alzheimer's pathology Shi, Liu; Winchester, Laura M.; Westwood, Sarah; Baird, Alison L.; Anand, Sneha N.; Buckley, Noel J.; Hye, Abdul; Ashton, Nicholas J.; Bos, Isabelle; Vos, Stephanie J. B.; ten Kate, Mara; Scheltens, Philip; Teunissen, Charlotte E.; Vandenberghe, Rik; Gabel, Silvy; Meersmans, Karen; Engelborghs, Sebastiaan; De Roeck, Ellen E.; Sleegers, Kristel; Frisoni, Giovanni B.; Blin, Olivier; Richardson, Jill C.; Bordet, Regis; Molinuevo, Jose L.; Rami, Lorena; Wallin, Anders; Kettunen, Petronella; Tsolaki, Magda; Verhey, Frans; Lleo, Alberto; Sala, Isabel; Popp, Julius; Peyratout, Gwendoline; Martinez-Lage, Pablo; Tainta, Mikel; Johannsen, Peter; Freund-Levi, Yvonne; Froeich, Lutz; Dobricic, Valerija; Legido-Quigley, Cristina; Barkhof, Frederik; Andreasson, Ulf; Blennow, Kaj; Zetterberg, Henrik; Streffer, Johannes; Lill, Christina M.; Bertram, Lars; Visser, Pieter Jelle; Kolb, Hartmuth C.; Narayan, Vaibhav A.; Lovestone, Simon; Nevado-Holgado, Alejo J. 分享 收藏
Dickkopf-1 Overexpression in vitro Nominates Candidate Blood Biomarkers Relating to Alzheimer's Disease Pathology 体外Dickkopf-1过表达提名与阿尔茨海默病病理相关的候选血液生物标志物 Shi, Liu; Winchester, Laura M.; Liu, Benjamine Y.; Killick, Richard; Ribe, Elena M.; Westwood, Sarah; Baird, Alison L.; Buckley, Noel J.; Hong, Shengjun; Dobricic, Valerija; Kilpert, Fabian; Franke, Andre; Kiddle, Steven; Sattlecker, Martina; Dobson, Richard; Cuadrado, Antonio; Hye, Abdul; Ashton, Nicholas J.; Morgan, Angharad R.; Bos, Isabelle; Vos, Stephanie J. B.; ten Kate, Mara; Scheltens, Philip; Vandenberghe, Rik; Gabel, Silvy; Meersmans, Karen; Engelborghs, Sebastiaan; De Roeck, Ellen E.; Sleegers, Kristel; Frisoni, Giovanni B.; Blin, Olivier; Richardson, Jill C.; Bordet, Regis; Molinuevo, Jose L.; Rami, Lorena; Wallin, Anders; Kettunen, Petronella; Tsolaki, Magda; Verhey, Frans; Lleo, Alberto; Alcolea, Daniel; Popp, Julius; Peyratout, Gwendoline; Martinez-Lage, Pablo; Tainta, Mikel; Johannsen, Peter; Teunissen, Charlotte E.; Freund-Levi, Yvonne; Frolich, Lutz; Legido-Quigley, Cristina; Barkhof, Frederik; Blennow, Kaj; Rasmussen, Katrine Laura; Nordestgaard, Borge Gronne; Frikke-Schmidt, Ruth; Nielsen, Sune Fallgaard; Soininen, Hilkka; Vellas, Bruno; Kloszewska, Iwona; Mecocci, Patrizia; Zetterberg, Henrik; Morgan, B. Paul; Streffer, Johannes; Visser, Pieter Jelle; Bertram, Lars; Nevado-Holgado, Alejo J.; Lovestone, Simon 分享 收藏
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Validation of Plasma Proteomic Biomarkers Relating to Brain Amyloid Burden in the EMIF-Alzheimer's Disease Multimodal Biomarker Discovery Cohort EMIF-阿尔茨海默病多模式生物标志物发现队列中与脑淀粉样蛋白负荷相关的血浆蛋白质组学生物标志物的验证 Westwood, Sarah; Baird, Alison L.; Anand, Sneha N.; Nevado-Holgado, Alejo J.; Kormilitzin, Andrey; Shi, Liu; Hye, Abdul; Ashton, Nicholas J.; Morgan, Angharad R.; Bos, Isabelle; Vos, Stephanie J. B.; Baker, Susan; Buckley, Noel J.; Ten Kate, Mara; Scheltens, Philip; Teunissen, Charlotte E.; Vandenberghe, Rik; Gabel, Silvy; Meersmans, Karen; Engelborghs, Sebastiaan; De Roeck, Ellen E.; Sleegers, Kristel; Frisoni, Giovanni B.; Blin, Olivier; Richardson, Jill C.; Bordet, Regis; Molinuevo, Jose L.; Rami, Lorena; Wallin, Anders; Kettunen, Petronella; Tsolaki, Magda; Verhey, Frans; Lleo, Alberto; Sala, Isabel; Popp, Julius; Peyratout, Gwendoline; Martinez-Lage, Pablo; Tainta, Mikel; Johannsen, Peter; Freund-Levi, Yvonne; Froelich, Lutz; Dobricic, Valerija; Legido-Quigley, Cristina; Bertram, Lars; Barkhof, Frederik; Zetterberg, Henrik; Morgan, B. Paul; Streffer, Johannes; Visser, Pieter Jelle; Lovestone, Simon 分享 收藏
Discovery and validation of plasma proteomic biomarkers relating to brain amyloid burden by SOMAscan assay 通过SOMAscan分析发现和验证与脑淀粉样蛋白负荷有关的血浆蛋白质组生物标志物 Shi, Liu; Westwood, Sarah; Baird, Alison L.; Winchester, Laura; Dobricic, Valerija; Kilpert, Fabian; Hong, Shengjun; Franke, Andre; Hye, Abdul; Ashton, Nicholas J.; Morgan, Angharad R.; Bos, Isabelle; Vos, Stephanie J. B.; Buckley, Noel J.; ten Kate, Mara; Scheltens, Philip; Vandenberghe, Rik; Gabel, Silvy; Meersmans, Karen; Engelborghs, Sebastiaan; De Roeck, Ellen E.; Sleegers, Kristel; Frisoni, Giovanni B.; Blin, Olivier; Richardson, Jill C.; Bordet, Regis; Molinuevo, Jose L.; Rami, Lorena; Wallin, Anders; Kettunen, Petronella; Tsolaki, Magda; Verhey, Frans; Lleo, Alberto; Alcolea, Daniel; Popp, Julius; Peyratout, Gwendoline; Martinez-Lage, Pablo; Tainta, Mikel; Johannsen, Peter; Teunissen, Charlotte E.; Freund-Levi, Yvonne; Froelich, Lutz; Legido-Quigley, Cristina; Barkhof, Frederik; Blennow, Kaj; Zetterberg, Henrik; Baker, Susan; Morgan, B. Paul; Streffer, Johannes; Visser, Pieter Jelle; Bertram, Lars; Lovestone, Simon; Nevado-Holgado, Alejo J. 分享 收藏
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