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Lukas Vlahos

columbia university
H指数:9
被引数:1,169

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Systematic design of combination therapy by targeting master regulators of coexisting diffuse midline glioma cell states

通过靶向共存的弥漫性中线胶质瘤细胞状态的主调节因子进行联合治疗的系统设计

2026-04-220
OAAI
Discovery and validation of effective combination therapies targeting cell state-specific master regulator vulnerabilities by network-based protein activity inference in diffuse midline glioma
2024-03-220
PRE
Tumor Explants Elucidate a Cascade of Paracrine SHH, WNT, and VEGF Signals Driving Pancreatic Cancer Angiosuppression

肿瘤外植体阐明了驱动胰腺癌血管抑制的旁分泌SHH,WNT和VEGF信号的级联

2023-11-144
OA
A SYSTEMS BIOLOGY APPROACH TO DEFINING AND TARGETING CELL STATE-SPECIFIC MASTER REGULATOR DEPENDENCIES IN DIFFUSE MIDLINE GLIOMA
2023-06-122
OAAI
Single-Cell Genomics Reveals a Novel Cell State During Smooth Muscle Cell Phenotypic Switching and Potential Therapeutic Targets for Atherosclerosis in Mouse and Human

单细胞基因组学揭示了平滑肌细胞表型转换过程中的一种新细胞状态,以及小鼠和人类动脉粥样硬化的潜在治疗靶点

2020-11-24328
OAAI