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P

Pasquale Laise

columbia university
H指数:15
被引数:3,263

个人简介

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教育背景

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工作经历

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荣誉奖项

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Developmental and MAPK-responsive transcription factors regulate distinct malignant cell states and associated genetic dependencies in pancreatic cancer

发育和MAPK应答转录因子调控胰腺癌中特异的恶性细胞状态及相关遗传依赖性

Nature Genetics
IF29
2026-08-260
OA
Pasquale Laise; Mikko Turunen; Alvaro Curiel-Garcia; Lorenzo Tomassoni; H. Carlo Maurer; Ela Elyada; Bernhard Schmierer; Jeremy Worley; Jordan Kesner; Xiangtian Tan; Ester Calvo Fernandez; Yuanqing Xue; Yining Chen; Kelly Wong; Urszula N. Wasko; Somnath Tagore; Alexander L. E. Wang; Sabrina Ge; Alina C. Iuga; Aaron T. Griffin; Winston Wong; Gulam A. Manji; Mariano J. Alvarez; Faiyaz Notta; David A. Tuveson; Kenneth P. Olive; Andrea Califano
Systematic design of combination therapy by targeting master regulators of coexisting diffuse midline glioma cell states

通过靶向共存的弥漫性中线胶质瘤细胞状态的主调节因子进行联合治疗的系统设计

Nature Genetics
IF29
2026-04-220
OAAI
Ester Calvo Fernández; Lorenzo Tomassoni; Xu Zhang; Junqiang Wang; Aleksandar Obradovic; Pasquale Laise; Aaron T. Griffin; Lukas Vlahos; Hanna E. Minns; Diana V. Morales; Christian Simmons; Matthew Gallitto; Hong-Jian Wei; Timothy J. Martins; Pamela S. Becker; John R. Crawford; Theophilos Tzaridis; Robert J. Wechsler-Reya; James Garvin; Robyn D. Gartrell; Luca Szalontay; Stergios Zacharoulis; Cheng-Chia Wu; Zhiguo Zhang; Andrea Califano; Jovana Pavisic
Discovery and validation of effective combination therapies targeting cell state-specific master regulator vulnerabilities by network-based protein activity inference in diffuse midline glioma
CANCER RESEARCH
IF16.6
2024-03-220
PRE
Fernandez, Ester Calvo; Tomassoni, Lorenzo; Zhang, Xu; Obradovic, Aleksandar; Laise, Pasquale; Griffin, Aaron T.; Vlahos, Lukas; Wang, Junqiang; Minns, Hanna E.; Morales, Diana V.; Simmons, Christian; Gallito, Matthew; Wei, Hong-Jian; Zhang, Zhiguo; Gartrell, Robyn; Szalontay, Luca; Zacharoulis, Stergios; Wu, Cheng-Chia; Califano, Andrea; Pavisic, Jovana
Tff2 defines transit-amplifying pancreatic acinar progenitors that lack regenerative potential and are protective against Kras-driven carcinogenesis

Tff2定义了缺乏再生潜力并对Kras驱动的致癌作用具有保护作用的转运放大胰腺腺泡祖细胞

CELL STEM CELL
IF20.4
2023-08-0110
OAAI
Jiang, Zhengyu; Wu, Feijing; Laise, Pasquale; Takayuki, Tanaka; Na, Fu; Kim, Woosook; Kobayashi, Hiroki; Chang, Wenju; Takahashi, Ryota; Valenti, Giovanni; Sunagawa, Masaki; White, Ruth A.; Macchini, Marina; Renz, Bernhard W.; Middelhoff, Moritz; Hayakawa, Yoku; Dubeykovskaya, Zinaida A.; Tan, Xiangtian; Chu, Timothy H.; Nagar, Karan; Tailor, Yagnesh; Belin, Bryana R.; Anand, Akanksha; Asfaha, Samuel; Finlayson, Michael O.; Iuga, Alina C.; Califano, Andrea; Wang, Timothy C.
Adult enteric Dclk1-positive glial and neuronal cells reveal distinct responses to acute intestinal injury

成人肠Dclk1-positive神经胶质和神经元细胞对急性肠损伤有不同的反应

AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY
IF3.3
2022-06-015
OA
Middelhoff, Moritz; Valenti, Giovanni; Tomassoni, Lorenzo; Ochiai, Yosuke; Belin, Bryana; Takahashi, Ryota; Malagola, Ermanno; Nienhueser, Henrik; Finlayson, Michael; Hayakawa, Yoku; Zamechek, Leah B.; Renz, Bernhard W.; Westphalen, C. Benedikt; Quante, Michael; Margolis, Kara G.; Sims, Peter A.; Laise, Pasquale; Califano, Andrea; Rao, Meenakshi; Gershon, Michael D.; Wang, Timothy C.
Single-Cell Genomics Reveals a Novel Cell State During Smooth Muscle Cell Phenotypic Switching and Potential Therapeutic Targets for Atherosclerosis in Mouse and Human

单细胞基因组学揭示了平滑肌细胞表型转换过程中的一种新细胞状态，以及小鼠和人类动脉粥样硬化的潜在治疗靶点

CIRCULATION
IF38.6
2020-11-24328
OAAI
Pan, Huize; Xue, Chenyi; Auerbach, Benjamin J.; Fan, Jiaxin; Bashore, Alexander C.; Cui, Jian; Yang, Dina Y.; Trignano, Sarah B.; Liu, Wen; Shi, Jianting; Ihuegbu, Chinyere O.; Bush, Erin C.; Worley, Jeremy; Vlahos, Lukas; Laise, Pasquale; Solomon, Robert A.; Connolly, Edward S.; Califano, Andrea; Sims, Peter A.; Zhang, Hanrui; Li, Mingyao; Reilly, Muredach P.
A cell-of-origin epigenetic tracer reveals clinically distinct subtypes of high-grade serous ovarian cancer
GENOME MEDICINE
IF11.2
2020-10-3017
OAAI
Lo Riso, Pietro; Villa, Carlo Emanuele; Gasparoni, Gilles; Vingiani, Andrea; Luongo, Raffaele; Manfredi, Anna; Jungmann, Annemarie; Bertolotti, Alessia; Borgo, Francesca; Garbi, Annalisa; Lupia, Michela; Laise, Pasquale; Das, Vivek; Pruneri, Giancarlo; Viale, Giuseppe; Colombo, Nicoletta; Manzo, Teresa; Nezi, Luigi; Cavallaro, Ugo; Cacchiarelli, Davide; Walter, Joern; Testa, Giuseppe
Cross-Species Single-Cell Analysis of Pancreatic Ductal Adenocarcinoma Reveals Antigen-Presenting Cancer-Associated Fibroblasts

胰腺导管腺癌的跨物种单细胞分析揭示了抗原呈递癌症相关的成纤维细胞

CANCER DISCOVERY
IF33.3
2019-08-011.3K
OAAI
Elyada, Ela; Bolisetty, Mohan; Laise, Pasquale; Flynn, William F.; Courtois, Elise T.; Burkhart, Richard A.; Teinor, Jonathan A.; Belleau, Pascal; Biffi, Giulia; Lucito, Matthew S.; Sivajothi, Santhosh; Armstrong, Todd D.; Engle, Dannielle D.; Yu, Kenneth H.; Hao, Yuan; Wolfgang, Christopher L.; Park, Youngkyu; Preall, Jonathan; Jaffee, Elizabeth M.; Califano, Andrea; Robson, Paul; Tuveson, David A.

研究方向

暂未获取到该数据
A
Andrea Califano
H 指数:96论文数:1,072被引数:5.4万
G
Giuseppe Testa
H 指数:50论文数:302被引数:9,697
L
Lorenzo Tomassoni
H 指数:8论文数:110被引数:419
L
Lukas Vlahos
H 指数:9论文数:102被引数:1,169
T
Timothy C. Wang
H 指数:128论文数:1,165被引数:9.0万
K
Kenneth P. Olive
H 指数:44论文数:482被引数:1.5万
G
Giancarlo Pruneri
H 指数:83论文数:992被引数:2.8万
A
Aaron T. Griffin
H 指数:9论文数:39被引数:471
E
Ester Calvo Fernández
H 指数:5论文数:30被引数:124
G
Giovanni Valenti
H 指数:44论文数:247被引数:6,439