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收藏Event-free survival in early polycythemia vera patients correlates with molecular response to ropeginterferon alfa-2b or hydroxyurea/best available therapy (PROUD-PV/CONTINUATION-PV)早期真性红细胞增多症患者的无事件生存率与对alfa-2b或羟基脲/最佳可用疗法 (PROUD-PV/CONTINUATION-PV) 的分子反应相关
Kiladjian, Jean-Jacques; Klade, Christoph; Georgiev, Pencho; Krochmalczyk, Dorota; Gercheva-Kyuchukova, Liana; Egyed, Miklos; Dulicek, Petr; Illes, Arpad; Pylypenko, Halyna; Sivcheva, Lylia; Mayer, Jiri; Yablokova, Vera; Krejcy, Kurt; Empson, Victoria; Hasselbalch, Hans C.; Kralovics, Robert; Gisslinger, Heinz 分享 收藏 分享 收藏 Event-free survival in patients with polycythemia vera treated with ropeginterferon alfa-2b versus best available treatmentGisslinger, Heinz; Klade, Christoph; Georgiev, Pencho; Krochmalczyk, Dorota; Gercheva-Kyuchukova, Liana; Egyed, Miklos; Dulicek, Petr; Illes, Arpad; Pylypenko, Halyna; Sivcheva, Lylia; Mayer, Jiri; Yablokova, Vera; Krejcy, Kurt; Empson, Victoria; Hasselbalch, Hans C.; Kralovics, Robert; Kiladjian, Jean-Jacques; PROUD-PV Study Grp 分享 收藏 Phenotypic characterization of disease-initiating stem cells in JAK2- or CALR-mutated myeloproliferative neoplasmsIvanov, Daniel; Milosevic Feenstra, Jelena D.; Sadovnik, Irina; Herrmann, Harald; Peter, Barbara; Willmann, Michael; Greiner, Georg; Slavnitsch, Katharina; Hadzijusufovic, Emir; Ruelicke, Thomas; Dahlhoff, Maik; Hoermann, Gregor; Machherndl-Spandl, Sigrid; Eisenwort, Gregor; Fillitz, Michael; Sliwa, Thamer; Krauth, Maria-Theresa; Bettelheim, Peter; Sperr, Wolfgang R.; Koller, Elisabeth; Pfeilstoecker, Michael; Gisslinger, Heinz; Keil, Felix; Kralovics, Robert; Valent, Peter 分享 收藏 分享 收藏 Long-term outcomes of polycythemia vera patients treated with ropeginterferon Alfa-2bKiladjian, Jean-Jacques; Klade, Christoph; Georgiev, Pencho; Krochmalczyk, Dorota; Gercheva-Kyuchukova, Liana; Egyed, Miklos; Dulicek, Petr; Illes, Arpad; Pylypenko, Halyna; Sivcheva, Lylia; Mayer, Jiri; Yablokova, Vera; Krejcy, Kurt; Empson, Victoria; Hasselbalch, Hans C.; Kralovics, Robert; Gisslinger, Heinz 分享 收藏 PD-L1 overexpression correlates with JAK2-V617F mutational burden and is associated with 9p uniparental disomy in myeloproliferative neoplasmsMilosevic Feenstra, Jelena D.; Jaeger, Roland; Schischlik, Fiorella; Ivanov, Daniel; Eisenwort, Gregor; Rumi, Elisa; Schuster, Michael; Gisslinger, Bettina; Machherndl-Spandl, Sigrid; Bettelheim, Peter; Krauth, Maria-Theresa; Keil, Felix; Bock, Christoph; Cazzola, Mario; Gisslinger, Heinz; Kralovics, Robert; Valent, Peter 分享 收藏 Genome-wide association study identifies susceptibility loci for acute myeloid leukemia (vol 13, 2, 2022)Lin, Wei-Yu; Fordham, Sarah E.; Hungate, Eric; Sunter, Nicola J.; Elstob, Claire; Xu, Yaobo; Park, Catherine; Quante, Anne; Strauch, Konstantin; Gieger, Christian; Skol, Andrew; Rahman, Thahira; Sucheston-Campbell, Lara; Wang, Junke; Hahn, Theresa; Clay-Gilmour, Alyssa I.; Jones, Gail L.; Marr, Helen J.; Jackson, Graham H.; Menne, Tobias; Collin, Mathew; Ivey, Adam; Hills, Robert K.; Burnett, Alan K.; Russell, Nigel H.; Fitzgibbon, Jude; Larson, Richard A.; Le Beau, Michelle M.; Stock, Wendy; Heidenreich, Olaf; Alharbi, Abrar; Allsup, David J.; Houlston, Richard S.; Norden, Jean; Dickinson, Anne M.; Douglas, Elisabeth; Lendrem, Clare; Daly, Ann K.; Palm, Louise; Piechocki, Kim; Jeffries, Sally; Bornhauser, Martin; Rollig, Christoph; Altmann, Heidi; Ruhnke, Leo; Kunadt, Desiree; Wagenfuhr, Lisa; Cordell, Heather J.; Darlay, Rebecca; Andersen, Mette K.; Fontana, Maria C.; Martinelli, Giovanni; Marconi, Giovanni; Sanz, Miguel A.; Cervera, Jose; Gomez-Segui, Ines; Cluzeau, Thomas; Moreilhon, Chimene; Raynaud, Sophie; Sill, Heinz; Voso, Maria Teresa; Lo-Coco, Francesco; Dombret, Herve; Cheok, Meyling; Preudhomme, Claude; Gale, Rosemary E.; Linch, David; Gaal-Wesinger, Julia; Masszi, Andras; Nowak, Daniel; Hofmann, Wolf-Karsten; Gilkes, Amanda; Porkka, Kimmo; Milosevic Feenstra, Jelena D.; Kralovics, Robert; Grimwade, David; Meggendorfer, Manja; Haferlach, Torsten; Krizsan, Szilvia; Bodor, Csaba; Stolzel, Friedrich; Onel, Kenan; Allan, James M. 分享 收藏 Genome-wide association study identifies susceptibility loci for acute myeloid leukemiaLin, Wei-Yu; Fordham, Sarah E.; Hungate, Eric; Sunter, Nicola J.; Elstob, Claire; Xu, Yaobo; Park, Catherine; Quante, Anne; Strauch, Konstantin; Gieger, Christian; Skol, Andrew; Rahman, Thahira; Sucheston-Campbell, Lara; Wang, Junke; Hahn, Theresa; Clay-Gilmour, Alyssa I.; Jones, Gail L.; Marr, Helen J.; Jackson, Graham H.; Menne, Tobias; Collin, Mathew; Ivey, Adam; Hills, Robert K.; Burnett, Alan K.; Russell, Nigel H.; Fitzgibbon, Jude; Larson, Richard A.; Le Beau, Michelle M.; Stock, Wendy; Heidenreich, Olaf; Alharbi, Abrar; Allsup, David J.; Houlston, Richard S.; Norden, Jean; Dickinson, Anne M.; Douglas, Elisabeth; Lendrem, Clare; Daly, Ann K.; Palm, Louise; Piechocki, Kim; Jeffries, Sally; Bornhauser, Martin; Rollig, Christoph; Altmann, Heidi; Ruhnke, Leo; Kunadt, Desiree; Wagenfuhr, Lisa; Cordell, Heather J.; Darlay, Rebecca; Andersen, Mette K.; Fontana, Maria C.; Martinelli, Giovanni; Marconi, Giovani; Sanz, Miguel A.; Cervera, Jose; Gomez-Segui, Ines; Cluzeau, Thomas; Moreilhon, Chimene; Raynaud, Sophie; Sill, Heinz; Voso, Maria Teresa; Lo-Coco, Francesco; Dombret, Herve; Cheok, Meyling; Preudhomme, Claude; Gale, Rosemary E.; Linch, David; Gaal-Wesinger, Julia; Masszi, Andras; Nowak, Daniel; Hofmann, Wolf-Karsten; Gilkes, Amanda; Porkka, Kimmo; Milosevic Feenstra, Jelena D.; Kralovics, Robert; Grimwade, David; Meggendorfer, Manja; Haferlach, Torsten; Krizsan, Szilvia; Bodor, Csaba; Stolzel, Friedrich; Onel, Kenan; Allan, James M. 分享 收藏 High-throughput drug screening identifies the ATR-CHK1 pathway as a therapeutic vulnerability of CALR mutated hematopoietic cellsJia, Ruochen; Kutzner, Leon; Koren, Anna; Runggatscher, Kathrin; Majek, Peter; Mueller, Andre C.; Schuster, Michael; Bock, Christoph; Loizou, Joanna I.; Kubicek, Stefan; Kralovics, Robert 分享 收藏 Hematopoietic expression of a chimeric murine-human CALR oncoprotein allows the assessment of anti-CALR antibody immunotherapies in vivoAchyutuni, Sarada; Nivarthi, Harini; Majoros, Andrea; Hug, Eva; Schueller, Christina; Jia, Ruochen; Varga, Cecilia; Schuster, Michael; Senekowitsch, Martin; Tsiantoulas, Dimitris; Kavirayani, Anoop; Binder, Christoph J.; Bock, Christoph; Zagrijtschuk, Oleh; Kralovics, Robert 分享 收藏 Precision Medicine in Hematology 2021: Definitions, Tools, Perspectives, and Open Questions血液学2021中的精准医学: 定义、工具、观点和开放性问题Valent, Peter; Orfao, Alberto; Kubicek, Stefan; Staber, Philipp; Haferlach, Torsten; Deininger, Michael; Kollmann, Karoline; Lion, Thomas; Virgolini, Irene; Winter, Georg; Hantschel, Oliver; Kenner, Lukas; Zuber, Johannes; Grebien, Florian; Moriggl, Richard; Hoermann, Gregor; Hermine, Olivier; Andreeff, Michael; Bock, Christoph; Mughal, Tariq; Constantinescu, Stefan N.; Kralovics, Robert; Sexl, Veronika; Skoda, Radek; Superti-Furga, Giulio; Jaeger, Ulrich 分享 收藏 Ropeginterferon Alfa-2b: Efficacy and Safety in Different Age GroupsGisslinger, Heinz; Klade, Christoph; Georgiev, Pencho; Krochmalczyk, Dorota; Gercheva-Kyuchukova, Liana; Egyed, Miklos; Rossiev, Viktor; Dulicek, Petr; Illes, Arpad; Pylypenko, Halyna; Sivcheva, Lylia; Mayer, Jiri; Yablokova, Vera; Krejcy, Kurt; Hasselbalch, Hans C.; Kralovics, Robert; Kiladjian, Jean-Jacques 分享 收藏 Ropeginterferon alfa-2b versus standard therapy for polycythaemia vera (PROUD-PV and CONTINUATION-PV): a randomised, non-inferiority, phase 3 trial and its extension studyGisslinger, Heinz; Klade, Christoph; Georgiev, Pencho; Krochmalczyk, Dorota; Gercheva-Kyuchukova, Liana; Egyed, Miklos; Rossiev, Viktor; Dulicek, Petr; Illes, Arpad; Pylypenko, Halyna; Sivcheva, Lylia; Mayer, Jiri; Yablokova, Vera; Krejcy, Kurt; Grohmann-Izay, Barbara; Hasselbalch, Hans C.; Kralovics, Robert; Kiladjian, Jean-Jacques 分享 收藏 Knock-in of murine Calr del52 induces essential thrombocythemia with slow-rising dominance in mice and reveals key role of Calr exon 9 in cardiac developmentBalligand, Thomas; Achouri, Younes; Pecquet, Christian; Gaudray, Gilles; Colau, Didier; Hug, Eva; Rahmani, Yacine; Stroobant, Vincent; Plo, Isabelle; Vainchenker, William; Kralovics, Robert; Van den Eynde, Benoit J.; Defour, Jean-Philippe; Constantinescu, Stefan N. 分享 收藏 MTHFD1 interaction with BRD4 links folate metabolism to transcriptional regulationMTHFD1与BRD4的相互作用将叶酸代谢与转录调控联系起来Sdelci, Sara; Rendeiro, Andre F.; Rathert, Philipp; You, Wanhui; Lin, Jung-Ming G.; Ringler, Anna; Hofstaetter, Gerald; Moll, Herwig P.; Guertl, Bettina; Farlik, Matthias; Schick, Sandra; Klepsch, Freya; Oldach, Matthew; Buphamalai, Pisanu; Schischlik, Fiorella; Majek, Peter; Parapatics, Katja; Schmidl, Christian; Schuster, Michael; Penz, Thomas; Buckley, Dennis L.; Hudecz, Otto; Imre, Richard; Wang, Shuang-Yan; Maric, Hans Michael; Kralovics, Robert; Bennett, Keiryn L.; Mueller, Andre C.; Mechtler, Karl; Menche, Joerg; Bradner, James E.; Winter, Georg E.; Klavins, Kristaps; Casanova, Emilio; Bock, Christoph; Zuber, Johannes; Kubicek, Stefan 分享 收藏 High activation of STAT5A drives peripheral T-cell lymphoma and leukemiaSTAT5A的高激活驱动外周T细胞淋巴瘤和白血病Maurer, Barbara; Nivarthi, Harini; Wingelhofer, Bettina; Ha Thi Thanh Pham; Schlederer, Michaela; Suske, Tobias; Grausenburger, Reinhard; Schiefer, Ana-Iris; Prchal-Murphy, Michaela; Chen, Doris; Winkler, Susanne; Merkel, Olaf; Kornauth, Christoph; Hofbauer, Maximilian; Hochgatterer, Birgit; Hoermann, Gregor; Hoelbl-Kovacic, Andrea; Prochazkova, Jana; Lobello, Cosimo; Cumaraswamy, Abbarna A.; Latzka, Johanna; Kitzwoegerer, Melitta; Chott, Andreas; Janikova, Andrea; Pospisilova, Sarka; Loizou, Joanna, I; Kubicek, Stefan; Valent, Peter; Kolbe, Thomas; Grebien, Florian; Kenner, Lukas; Gunning, Patrick T.; Kralovics, Robert; Herling, Marco; Mueller, Mathias; Ruelicke, Thomas; Sexl, Veronika; Moriggl, Richard 分享 收藏 International external quality assurance of JAK2 V617F quantificationAsp, Julia; Skov, Vibe; Bellosillo, Beatriz; Kristensen, Thomas; Lippert, Eric; Dicker, Frank; Schwarz, Jiri; Wojtaszewska, Marzena; Palmqvist, Lars; Akiki, Susanna; Aggerholm, Anni; Andersen, Morten Tolstrup; Girodon, Francois; Kjaer, Lasse; Leibundgut, Elisabeth Oppliger; Pancrazzi, Alessandro; Vorland, Marta; Andrikovics, Hajnalka; Kralovics, Robert; Cassinat, Bruno; Coucelo, Margarida; Eftimov, Aleksandar; Haslam, Karl; Kusec, Rajko; Link-Lenczowska, Dorota; Lode, Laurence; Matiakowska, Karolina; Naguib, Dina; Navaglia, Filippo; Novotny, Guy Wayne; Percy, Melanie J.; Sudarikov, Andrey; Hermouet, Sylvie; Pallisgaard, Niels 分享 收藏 Ropeginterferon alpha-2b targets JAK2V617F-positive polycythemia vera cells in vitro and in vivoVerger, Emmanuelle; Soret-Dulphy, Juliette; Maslah, Nabih; Roy, Lydia; Rey, Jerome; Ghrieb, Zineb; Kralovics, Robert; Gisslinger, Heinz; Grohmann-Izay, Barbara; Klade, Christoph; Chomienne, Christine; Giraudier, Stephane; Cassinat, Bruno; Kiladjian, Jean-Jacques 分享 收藏 
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