M. Groll - Publications, H-index & Citations

M. Groll

tu munich

70H指数

635论文数

1.9W被引数

收录论文 149

发表时间

Biosynthesis of the Fully Saturated C16 Homosesquiterpene Descartane Through Deprotonation With Cyclopropanation 通过环丙烷化脱质子化合成全饱和C16同倍半萜Descartane的生物合成途径

Angewandte Chemie-International Edition

IF16.9

2026-07-27

OAAI

Kexin Yang; Philip Troycke; Bernd Goldfuss; Michael Groll; Jeroen S. Dickschat

Computational redesign and directed evolution of a lanthanide-dependent photoredox enzyme for enantioselective diol cleavage 镧系依赖性光氧化还原酶的计算重设计及其定向进化，用于手性二醇的拆分

chem. sci.

IF0

2026-03-18

OAAI

Florian Leiss-Maier; Joshua Behringer; Ghulam Mustafa; Anna Heider; Rahel Mühlhofer; Andreas Sebastian Sebastian Klein; Michael Groll; Cathleen Zeymer

Metronidazole and ether derivatives target Helicobacter pylori via simultaneous stress induction and inhibition 甲硝唑和醚衍生物通过同时诱导和抑制压力来靶向幽门螺杆菌

Nature Microbiology

IF19.4

2026-03-18

OAAI

Michaela K. Fiedler; Marianne S. I. Pandler; Ruolan Gong; Sonja Fuchs; Katharina Rox; Verena Friedrich; Dietmar Pfeiffer; Dharmesh Singh; Till Reinhardt; Cora Mibus; Matthias Huber; Corinna R. Hess; Raquel Mejías-Luque; Markus Gerhard; Michael Groll; Stephan A. Sieber

Structural basis of methylation-triggered terpene cyclization 甲硫基化触发的萜烯环化作用的结构基础

Chem

IF19.6

2026-03-17

OAAI

Michael Groll; Kexin Yang; Houchao Xu; Philip Troycke; Jeroen S. Dickschat

Enantiodivergent Evolution of a De Novo Protein for Enzymatic [2 + 2] Photocycloaddition Activity 手性发散式演化一种从头设计的蛋白质，用于酶促[2 + 2]光环加成活性

ACS Catalysis

IF13.1

2026-03-14

OAAI

Benedikt Boesen; Anna Heider; Jack M. O’Shea; Michael Groll; Thorsten Bach; Cathleen Zeymer

Structural Mimics of Hydrocarbon Intermediates Reveal Counterclockwise Cyclization Pathways in the Sesquiterpene Synthases TmS and NcECS 烃类中间体的结构类似物揭示了倍半萜烯合酶TmS和NcECS中的逆时针环化途径

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

IF15.6

2025-12-01

PREAI

Groll, Michael; Li, Heng; Troycke, Philip; Kaila, Ville R. I.; Dickschat, Jeroen S.

Tellurophene-Tagged Carfilzomib Enables Single-Cell Mass Cytometric Mapping of Proteasome Activity 二硒茂烯标记的卡非佐米实现了蛋白酶体活性的单细胞质谱成像分析

ACS Chemical Biology

IF3.8

2025-11-18

PREAI

Nicole Potter; Alexander Eddenden; Aleksandra Fomina; Anuroopa Dinesh; Hartland Warren Jackson; Alison P. McGuigan; Michael Groll; Mark Nitz

A Luminescence-Based Screening Platform for Lanthanide-Binding Peptides and Proteins 一种基于发光的镧系元素结合肽和蛋白质筛选平台

ACS Chemical Biology

IF3.8

2025-11-17

OAAI

Robert Klassen; Anna Heider; Hannah Kugler; Michael Groll; Cathleen Zeymer

Modular protein scaffold architecture and AI-guided sequence optimization facilitate de novo metalloenzyme engineering 模块化蛋白质支架架构和AI引导的序列优化促进从头金属酶工程

Structure

IF4.3

2025-11-05

OAAI

Paula Wagner Egea; Florent Delhommel; Ghulam Mustafa; Florian Leiss-Maier; Lisa Klimper; Thomas Badmann; Anna Heider; Idoia Wille; Michael Groll; Michael Sattler; Cathleen Zeymer

Hijacking a bacterial ABC transporter for genetic code expansion 劫持细菌ABC转运蛋白以扩展遗传密码

Nature

IF48.5

2025-10-15

OAAI

Tarun Iype; Maximilian Fottner; Paul Böhm; Carlos Piedrafita; Yannis Möller; Michael Groll; Kathrin Lang

Studies of α′,β′-Epoxyketone Synthesis by Small-Molecule Flavins and Flavoenzymes α′,β′-环氧酮合成的小分子黄素和黄素酶研究

Angewandte Chemie International Edition

IF16.9

2025-10-14

OAAI

Dr. Alexandra Walter; Dr. Wolfgang Kuttenlochner; Prof. Dr. Wolfgang Eisenreich; Chengyang Yao; Prof. Dr. Michael Groll; Dr. Golo Storch

Proteasome-associated autoinflammatory syndromes: The impact of mutations in proteasome subunits on particle assembly, structure, and activity 蛋白酶体相关自身炎症综合征：蛋白酶体亚基突变对颗粒组装、结构和活性的影响

Structure

IF4.3

2025-09-30

OAAI

Eva M. Huber; Wolfgang Heinemeyer; Michael Groll

Distal peptide elongation by a protease-like ligase and two distinct carrier proteins 蛋白酶样连接酶和两种不同的载体蛋白介导的远端肽链延长

Chem

IF19.6

2025-09-16

OAAI

Finn Gude; Annkathrin Bohne; Maria Dell; Jonathan Franke; Kyle L. Dunbar; Michael Groll; Christian Hertweck

Tailored SirReal-type inhibitors enhance SIRT2 inhibition through ligand stabilization and disruption of NAD⁺ co-factor binding 定制化的SirReal型抑制剂通过配体稳定化和破坏NAD⁺辅因子结合来增强SIRT2抑制。

RSC Med. Chem.

IF3.6

2025-08-22

OAAI

Ricky Wirawan; Matthias Frei; Anna Heider; Niklas Papenkordt; Florian Friedrich; Thomas Wein; Manfred Jung; Michael Groll; eva huber; Franz Bracher

Unraveling the molecular basis of substrate specificity and halogen activation in vanadium-dependent haloperoxidases 解析钒依赖性卤过氧化物酶底物特异性和卤素活化的分子基础

NATURE COMMUNICATIONS

IF15.7

2025-02-28

OAAI

Zeides, P.; Bellmann-Sickert, K.; Zhang, Ru; Seel, C. J.; Most, V.; Schoeder, C. T.; Groll, M.; Gulder, T.

Isofunctional but Structurally Different Methyltransferases for Dithiolopyrrolone Diversification 用于二硫代吡咯酮多样化的功能相同但结构不同的甲基转移酶

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

IF16.9

2024-10-18

OAAI

Su, Li; Huber, Eva M.; Westphalen, Margaretha; Gellner, Jonas; Bode, Edna; Koebel, Tania; Gruen, Peter; Alanjary, Mohammad M.; Glatter, Timo; Cirnski, Katarina; Mueller, Rolf; Schindler, Daniel; Groll, Michael; Bode, Helge B.

Bioengineering of syrbactin megasynthetases for immunoproteasome inhibitor production

CHEM

IF19.6

2024-10-01

OAAI

Praeve, Leonard; Kuttenlochner, Wolfgang; Tabak, Werner W. A.; Langer, Chiara; Kaiser, Markus; Groll, Michael; Bode, Helge B.

Deciphering the SAM- and metal-dependent mechanism of O-methyltransferases in cystargolide and belactosin biosynthesis: A structure-activity relationship study

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2024-09-01

OAAI

Kuttenlochner, Wolfgang; Beller, Patrick; Kaysser, Leonard; Groll, Michael

Macrocyclic Oxindole Peptide Epoxyketones-A Comparative Study of Macrocyclic Inhibitors of the 20S Proteasome

ACS MEDICINAL CHEMISTRY LETTERS

IF4

2024-03-27

OAAI

Goetz, Marion G.; Godwin, Kacey; Price, Rachel; Dorn, Robert; Merrill-Steskal, Gabriel; Klemmer, William; Hansen, Hunter; Produturi, Gautam; Rocha, Megan; Palmer, Mathias; Molacek, Lea; Strater, Zack; Groll, Michael

Polyketide Trimming Shapes Dihydroxynaphthalene-Melanin and Anthraquinone Pigments

ADVANCED SCIENCE

IF14.1

2024-03-16

OAAI

Schmalhofer, Maximilian; Vagstad, Anna; Zhou, Qiuqin; Bode, Helge; Groll, Michael

研究方向