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K

Koh Takeuchi

Chugai Pharmaceutical Co., Ltd.

42H指数
377论文数
7.2K被引数
收录论文 88
发表时间
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Phase Separation Driven by Dynamic Interactions in the N-Terminal Intrinsically Disordered Region of the DEAD-Box RNA Helicase DDX3X由DDX3X DEAD-Box RNA解旋酶N端固有无序区域动态相互作用驱动的相分离
errJournal of the American Chemical Society
IF15.6
err2026-05-20
err0
PREAI
errYuki Toyama; Shinichiro Inakami; Masaharu Takarada; Kohki Okabe; Koh Takeuchi; Ichio Shimada
err分享
err收藏
Polypharmacologic phosphoinositide modulation by FTY720 triggers endomembrane trafficking collapse and metabolic starvation in cancer cellsFTY720通过多药理磷酸肌醇调节触发癌细胞内质膜转运崩溃和代谢饥饿。
errBiochemical and Biophysical Research Communications
IF2.2
err2026-03-24
err0
errOAAI
errSatoshi Kofuji; Kazutaka Sumita; Yoshiki Ikeda; Yasufumi Takahashi; Sho Tabata; Doshun Ito; Yoshihisa Hirota; Mika Sasaki; Hirotaka Kanoh; Fubito Nakatsu; Koh Takeuchi; Toshiya Senda; Mindy I. Davis; Min Shen; Hiroaki Wakimoto; Akiyoshi Hirayama; Tomoyoshi Soga; Anton Simeonov; Atsuo T. Sasaki
err分享
err收藏
Revisiting fluorine relaxation: a perspective on fluorine NMR in structural and dynamic studies of biomolecules重新审视氟弛豫：关于氟核磁共振在生物分子结构与动力学研究中的视角
errJournal of Magnetic Resonance
IF1.9
err2026-02-01
err0
PREAI
errToyama, Yuki; Takeuchi, Koh; Shimada, Ichio
err分享
err收藏
A minimal RNA-cleaving DNAzyme and its catalytic mechanism最小RNA切割DNA酶及其催化机制
errNucleic Acids Research
IF13.1
err2026-01-27
err0
PREAI
errYamasaki, Kazuhiko; Inomata, Rika; Yamasaki, Tomoko; Kubota, Tomomi; Miyashita, Naoyuki; Takeuchi, Koh; Miyagishi, Makoto
err分享
err收藏
IMPDH and GTP Metabolism in Cancer: Mechanisms, Regulation, and Translational ScopeIMPDH与GTP代谢在癌症中的作用：机制、调控与转化范围
errCancer Science
IF4.3
err2025-10-03
err0
errOAAI
errAki Ogawa-Iio; Koh Takeuchi; Keita Shigemi; Michelle Jane Genoveso; Hiroaki Niitsu; Iemasa Koh; Yusei Ota; Keita Yamane; Takao Hinoi; Natsuki Osaka; Masashi Oshima; Tomohiro Ishikawa; Tomoyuki Mizuno; Manabu Natsumeda; Kensuke Tateishi; Rintaro Hashizume; Satoru Osuka; Susumu Goyama; Tomoharu Yasuda; Toshiya Senda; Atsuo T. Sasaki
err分享
err收藏
Two-step target recognition for the competitive inhibition activity of an anti-VEGF aptamer两步目标识别方法用于抗VEGF适配体的竞争性抑制活性研究
errRNA
IF5
err2025-10-01
err0
PREAI
errTakeuchi, Koh; Ueda, Takumi; Imai, Misaki; Fujisaki, Miwa; Tsujimura, Masanari; Tokunaga, Yuji; Kofuku, Yutaka; Shimada, Ichio
err分享
err收藏
Structural basis of the residence time of adenosine A2A receptor ligands revealed by NMR由NMR揭示的腺苷A2A受体配体停留时间的结构基础
errChem. Sci.
IF7.4
err2025-08-29
err0
errOAAI
errTakumi Ueda; Tomoki Tsuchida; Masanori Kurita; Takuya Mizumura; Shunsuke Imai; Yutaro Shiraishi; Yutaka Kofuku; Shukei Miyagawa; Kaori Fukuzawa; Koh Takeuchi; Ichio Shimada
err分享
err收藏
Leveraging relaxation-optimized 1H-13CF correlations in 4-19F-phenylalanine as atomic beacons for probing structure and dynamics of large proteins利用弛豫优化的1H-13C相关信号在4-19F-苯丙氨酸中的原子探针作用，探究大蛋白的结构与动态特性
errNATURE CHEMISTRY
IF20.2
err2025-05-05
err0
PREAI
errBoeszoermenyi, Andras; Radeva, Denitsa L.; Schindler, Sebastian; Valadares, Veronica; Padmanabha Das, Krishna M.; Dubey, Abhinav; Viennet, Thibault; Schmitt, Max; Kast, Peter; Gelev, Vladimir M.; Stoyanov, Nikolay; Burdzhiev, Nikola; Petrov, Ognyan; Ficarro, Scott; Marto, Jarred; Geffken, Ezekiel A.; Dhe-Paganon, Sirano; Seo, Hyuk-Soo; Alexander, Nathan D.; Cooley, Richard B.; Mehl, Ryan A.; Kovacs, Helena; Anklin, Clemens; Bermel, Wolfgang; Kuprov, Ilya; Takeuchi, Koh; Arthanari, Haribabu
err分享
err收藏
Estimating Counterfactual Treatment Outcomes Over Time in Complex Multiagent Scenarios
errIEEE TRANSACTIONS ON NEURAL NETWORKS AND LEARNING SYSTEMS
IF8.9
err2025-02-01
err0
errOAAI
errFujii, Keisuke; Takeuchi, Koh; Kuribayashi, Atsushi; Takeishi, Naoya; Kawahara, Yoshinobu; Takeda, Kazuya
err分享
err收藏
PI5P4K inhibitors: promising opportunities and challenges
errFEBS JOURNAL
IF4.2
err2025-01-19
err0
errOAAI
errTakeuchi, Koh; Nagase, Lisa; Kageyama, Shun; Kanoh, Hirotaka; Oshima, Masashi; Ogawa-Iio, Aki; Ikeda, Yoshiki; Fujii, Yuki; Kondo, Sei; Osaka, Natsuki; Masuda, Takeshi; Ishihara, Tsukasa; Nakamura, Yoshikazu; Hirota, Yoshihisa; Sasaki, Takehiko; Senda, Toshiya; Sasaki, Atsuo T.
err分享
err收藏
Bottom-up design of peptide shapes in water using oligomers of N-methyl-l/d-alanine利用N-甲基-L/D-丙氨酸寡聚物在水溶液中自下而上的设计肽形状
errCHEMICAL SCIENCE
IF7.4
err2025-01-01
err0
errOAAI
errMorimoto, Jumpei; Yokomine, Marin; Shiratori, Yota; Ueda, Takumi; Nakamuro, Takayuki; Takaba, Kiyofumi; Maki-Yonekura, Saori; Umezawa, Koji; Miyanishi, Koichiro; Fukuda, Yasuhiro; Watanabe, Takumu; Suga, Mayuko; Inayoshi, Ayumi; Yoshida, Takuya; Mizukami, Wataru; Takeuchi, Koh; Yonekura, Koji; Nakamura, Eiichi; Sando, Shinsuke
err分享
err收藏
ULK1-regulated AMP sensing by AMPK and its application for the treatment of chronic kidney diseaseAMPK检测ULK1-regulated AMP及其在慢性肾脏病治疗中的应用
errKIDNEY INTERNATIONAL
IF12.6
err2024-11-01
err0
errOAAI
errYanagi, Tomoki; Kikuchi, Hiroaki; Takeuchi, Koh; Susa, Koichiro; Mori, Takayasu; Chiga, Motoko; Yamamoto, Kouhei; Furukawa, Asuka; Kanazawa, Takumi; Kato, Yuki; Takahashi, Naohiro; Suzuki, Takefumi; Mori, Yutaro; Carter, Benjamin C.; Mori, Makiko; Nakano, Yuta; Fujiki, Tamami; Hara, Yu; Suzuki, Soichiro; Ando, Fumiaki; Mandai, Shintaro; Honda, Shinya; Torii, Satoru; Shimizu, Shigeomi; Tanaka, Hajime; Fujii, Yasuhisa; Rai, Tatemitsu; Uchida, Shinichi; Sohara, Eisei
err分享
err收藏
Molecular basis promoting centriole triplet microtubule assembly
errNATURE COMMUNICATIONS
IF15.7
err2024-03-22
err1
errOAAI
errTakeda, Yutaka; Chinen, Takumi; Honda, Shunnosuke; Takatori, Sho; Okuda, Shotaro; Yamamoto, Shohei; Fukuyama, Masamitsu; Takeuchi, Koh; Tomita, Taisuke; Hata, Shoji; Kitagawa, Daiju
err分享
err收藏
An N-ortho-nitrobenzylated benzanilide amino acid enables control of the conformation and membrane permeability of cyclic peptides
errCHEMICAL COMMUNICATIONS
IF4.2
err2024-01-01
err1
PREAI
errOtani, Yuko; Ichinose, Asami; Wang, Xihong; Huang, Zhihan; Kasahara, Akitomo; Ishii, Mayumi; Watanabe, Eri; Kanamitsu, Kayoko; Tai, Kempei; Kusuhara, Hiroyuki; Ueda, Takumi; Takeuchi, Koh; Ohwada, Tomohiko
err分享
err收藏
A high-resolution structural characterization and physicochemical study of how a peptoid binds to an oncoprotein MDM2
errCHEMICAL SCIENCE
IF7.4
err2024-01-01
err1
errOAAI
errYokomine, Marin; Morimoto, Jumpei; Fukuda, Yasuhiro; Ueda, Takumi; Takeuchi, Koh; Umezawa, Koji; Ago, Hideo; Matsuura, Hiroaki; Ueno, Go; Senoo, Akinobu; Nagatoishi, Satoru; Tsumoto, Kouhei; Sando, Shinsuke
err分享
err收藏
The oxidative folding of nascent polypeptides provides electrons for reductive reactions in the ER
errCELL REPORTS
IF6.9
err2023-07-01
err3
errOAAI
errUegaki, Kaiku; Tokunaga, Yuji; Inoue, Michio; Takashima, Seiji; Inaba, Kenji; Takeuchi, Koh; Ushioda, Ryo; Nagata, Kazuhiro
err分享
err收藏
Nonthermal acceleration of protein hydration by sub-terahertz irradiation
errNATURE COMMUNICATIONS
IF15.7
err2023-05-22
err10
errOAAI
errSugiyama, Jun-ichi; Tokunaga, Yuji; Hishida, Mafumi; Tanaka, Masahito; Takeuchi, Koh; Satoh, Daisuke; Imashimizu, Masahiko
err分享
err收藏
Amide-to-ester substitution as a stable alternative to N-methylation for increasing membrane permeability in cyclic peptides
errNATURE COMMUNICATIONS
IF15.7
err2023-03-17
err21
errOAAI
errHosono, Yuki; Uchida, Satoshi; Shinkai, Moe; Townsend, Chad E.; Kelly, Colin N.; Naylor, Matthew R.; Lee, Hsiau-Wei; Kanamitsu, Kayoko; Ishii, Mayumi; Ueki, Ryosuke; Ueda, Takumi; Takeuchi, Koh; Sugita, Masatake; Akiyama, Yutaka; Lokey, Scott R.; Morimoto, Jumpei; Sando, Shinsuke
err分享
err收藏
Functional molecular evolution of a GTP sensing kinase: PI5P4Kβ
errFEBS JOURNAL
IF4.2
err2023-03-10
err4
errOAAI
errTakeuchi, Koh; Senda, Miki; Ikeda, Yoshiki; Okuwaki, Koji; Fukuzawa, Kaori; Nakagawa, So; Sasaki, Mika; Sasaki, Atsuo T.; Senda, Toshiya
err分享
err收藏
Role of the Orphan Transporter SLC35E1 in the Nuclear Egress of Herpes Simplex Virus 1孤儿转运蛋白SLC35E1在单纯疱疹病毒1核出口中的作用
errJOURNAL OF VIROLOGY
IF3.8
err2022-05-25
err4
errOAAI
errMaeda, Fumio; Kato, Akihisa; Takeshima, Kosuke; Shibazaki, Misato; Sato, Ryota; Shibata, Takuma; Miyake, Kensuke; Kozuka-Hata, Hiroko; Oyama, Masaaki; Shimizu, Eigo; Imoto, Seiya; Miyano, Satoru; Adachi, Shungo; Natsume, Tohru; Takeuchi, Koh; Maruzuru, Yuhei; Koyanagi, Naoto; Jun, Arii; Yasushi, Kawaguchi
err分享
err收藏

研究方向

暂无研究方向
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