Zhe Zhuang

Stanford University

H指数:25

被引数:2,628

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Charged molecular glue discovery enabled by targeted degron display

靶向降解基序展示驱动的带电分子胶发现

Nature Chemical Biology

IF13.7

2026-04-060

OAAI

Development of FBXO22 Degraders and the Recruitment Ligand 2-Pyridinecarboxyaldehyde (2-PCA)

FBXO22降解剂的开发及招募配体2-吡啶甲酰肼(2-PCA)

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

IF15.6

2025-11-010

PRE

Rational Design of CDK12/13 and BRD4 Molecular Glue Degraders

CDK12/13和BRD4分子胶降解剂的合理设计

Angewandte Chemie International Edition

IF0

2025-07-080

PRE

Copper-Catalyzed γ-C(sp3)-H Lactamization and Iminolactonization

铜催化的 γ-c (sp3)-H内酰胺化和亚胺内酰胺化

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

IF16.9

2024-11-161

PRE

One-Step Synthesis of Chiral 9,10-Dihydrophenanthrenes via Ligand-Enabled Enantioselective Cascade β,γ-Diarylation of Acids

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

IF16.9

2024-09-020

PRE

Synthesis of chiral carbocycles via enantioselective β,γ-dehydrogenation

NATURE SYNTHESIS

IF20

2024-08-150

PRE

Versatile Copper-Catalyzed γ-C(sp3)-H Lactonization of Aliphatic Acids

多功能铜催化的脂肪酸的 γ-c (sp3)-H内酯化

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

IF15.6

2024-06-137

PRE

Synthesis of ß,γ-Unsaturated Aliphatic Acids via Ligand-Enabled Dehydrogenation

配体脱氢法合成 β，γ-不饱和脂肪酸

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

IF15.6

2023-09-1213

Enhancing Substrate-Metal Catalyst Affinity via Hydrogen Bonding: Pd(II)-Catalyzed β-C(sp3)-H Bromination of Free Carboxylic Acids

通过氢键增强底物-金属催化剂的亲和力: Pd(II) 催化的游离羧酸的 β-c (sp3)-H溴化

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

IF15.6

2023-07-2412

PRE

Ligand-Enabled β-C(sp3)-H Lactamization of Tosyl-Protected Aliphatic Amides Using a Practical Oxidant

使用实用氧化剂对甲苯磺酰基保护的脂族酰胺进行配体激活的 β-c (sp3)-H内酰胺化

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

IF16.9

2022-07-1422

OAAI

One-Step Synthesis of β-Alkylidene-γ-lactones via Ligand-Enabled β,γ-Dehydrogenation of Aliphatic Acids

通过配体使脂肪酸 β，γ-脱氢一步合成 β-亚烷基-γ-内酯

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

IF15.6

2022-07-0839

Roles of Ligand and Oxidant in Pd(II)-Catalyzed and Ligand-Enabled C(sp3)-H Lactonization in Aliphatic Carboxylic Acid: Mechanistic Studies

配体和氧化剂在脂肪族羧酸中Pd(II) 催化和配体激活的C(sp3)-H内酯化中的作用: 机理研究

ACS CATALYSIS

IF13.1

2022-04-1218

PRE

Palladium(II)-Catalyzed Selective Arylation of Tertiary C-H Bonds of Cyclobutylmethyl Ketones Using Transient Directing Groups

钯 (II) 催化的环丁基甲基酮叔c-h键的选择性芳基化

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

IF16.9

2022-03-092

Palladium-Catalyzed Enantioselective β-C(sp3)-H Activation Reactions of Aliphatic Acids: A Retrosynthetic Surrogate for Enolate Alkylation and Conjugate Addition

ACCOUNTS OF CHEMICAL RESEARCH

IF17.7

2022-01-2571

Unconventional mechanism and selectivity of the Pd-catalyzed C-H bond lactonization in aromatic carboxylic acid

NATURE COMMUNICATIONS

IF15.7

2022-01-1416

OAAI

Ligand Enabled Pd(II)-Catalyzed γ-C(sp3)-H Lactamization of Native Amides

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

IF15.6

2021-12-1629

Probing Catalyst Speciation in Pd-MPAAM-Catalyzed Enantioselective C(sp3)-H Arylation: Catalyst Improvement via Destabilization of Off-Cycle Species

ACS CATALYSIS

IF13.1

2021-08-2010

OAAI

Synthesis of Cyclic Anhydrides via Ligand-Enabled C-H Carbonylation of Simple Aliphatic Acids

通过配体使简单脂肪酸的c-h羰基化合成环酐

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

IF16.9

2021-06-1731

Rapid Construction of Tetralin, Chromane, and Indane Motifs via Cyclative C-H/C-H Coupling: Four-Step Total Synthesis of (±)-Russujaponol F

通过循环c-h/c-h偶联快速构建四氢化萘，色满和茚满基序: (±)-Russujaponol F的四步全合成

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

IF15.6

2021-01-0462

Pd(II)-Catalyzed Enantioselective γ-C(sp3)-H Functionalizations of Free Cyclopropylmethylamines

Pd(II) 催化的游离环丙基甲胺的对映选择性 γ-c (sp3)-H官能化

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

IF15.6

2020-07-0190

Zhe Zhuang

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