Dezerae Cox

university of cambridge

H指数:16

被引数:1,276

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Temporal Trajectories of the Tau Aggregate Interactome Reveal Stage-Specific Vulnerabilities in Alzheimer's Disease

tau聚集物互作组的时间轨迹揭示阿尔茨海默病中阶段特异性易损性

Advanced Science

IF14.1

2026-09-170

OAAI

Direct single-molecule visualization of Hsp90-mediated relief of an Hsp70-folding block

Hsp90介导的Hsp70折叠阻滞缓解的直接单分子可视化

Science Advances

IF12.5

2026-07-290

Nanoscopic tau aggregates are not shared intermediates but disease-specific entities across tauopathies

纳观级tau聚集物并非共享的中间体，而是跨tau蛋白病的疾病特异性实体。

Cell Reports

IF6.9

2026-02-190

OAAI

Differential inclusion formation of an aggregation-prone protein reveals differences in the proteostasis capacity of neuronal cell lines

易聚集蛋白的差异包含形成揭示了神经元细胞系中蛋白质稳态能力的差异

Biochimica et Biophysica Acta (BBA) - Molecular Cell Research

IF0

2026-02-170

OAAI

Quantitative Profiling of Nanoscopic Protein Aggregates Reveals Specific Fingerprint of TDP-43-Positive Assemblies in Motor Neuron Disease

纳米尺度蛋白聚集物的定量分析揭示运动神经元疾病中TDP-43阳性聚集物的特异指纹

Advanced Science

IF14.1

2025-09-230

OAAI

Single-Molecule Characterization and Super-Resolution Imaging of Alzheimer's Disease-Relevant Tau Aggregates in Human Samples

人类样品中阿尔茨海默病相关Tau聚集体的单分子表征和超分辨率成像

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

IF16.9

2024-04-173

Protein painting reveals pervasive remodeling of conserved proteostasis machinery in response to pharmacological stimuli

NPJ SYSTEMS BIOLOGY AND APPLICATIONS

IF3.5

2022-11-285

OAAI

Sequence grammar underlying the unfolding and phase separation of globular proteins

MOLECULAR CELL

IF16.6

2022-09-0142

OAAI

Deletion of the Plasmodium falciparum exported protein PTP7 leads to Maurer's clefts vesiculation, host cell remodeling defects, and loss of surface presentation of EMP1

PLOS PATHOGENS

IF4.9

2022-08-0511

OAAI

A biosensor of protein foldedness identifies increased holdase activity of chaperones in the nucleus following increased cytosolic protein aggregation

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2022-08-013

OAAI

Hidden information on protein function in censuses of proteome foldedness

NATURE COMMUNICATIONS

IF15.7

2022-04-149

OAAI

A Census of Hsp70-Mediated Proteome Solubility Changes upon Recovery from Heat Stress

JOURNAL OF PROTEOME RESEARCH

IF3.6

2022-04-073

PRE

PINK1 signalling in neurodegenerative disease

MOLECULAR MECHANISMS OF NEURODEGENERATION

IF0

2021-12-226

OAAI

Neurodegenerative disease-associated protein aggregates are poor inducers of the heat shock response in neuronal cells

神经退行性疾病相关蛋白聚集体是神经元细胞热休克反应的不良诱导物

JOURNAL OF CELL SCIENCE

IF3.6

2020-08-0511

OAAI

N- and C-terminal regions of ?B-crystallin and Hsp27 mediate inhibition of amyloid nucleation, fibril binding, and fibril disaggregation

的N-和C-末端区域？B-晶体蛋白和Hsp27介导淀粉样蛋白成核，原纤维结合和原纤维解聚的抑制

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2020-07-0127

OAAI

Arginine in C9ORF72 Dipolypeptides Mediates Promiscuous Proteome Binding and Multiple Modes of Toxicity

MOLECULAR & CELLULAR PROTEOMICS

IF5.5

2020-04-0128

OAAI

Protein aggregation in cell biology: An aggregomics perspective of health and disease

细胞生物学中的蛋白质聚集: 健康与疾病的聚集组学观点

SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

IF6

2020-03-0137

PRE

Widespread remodeling of proteome solubility in response to different protein homeostasis stresses

响应不同蛋白质稳态压力的蛋白质组溶解度的广泛重塑

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2020-01-2136

OAAI

Single-Molecule Characterization of the Interactions between Extracellular Chaperones and Toxic α-Synuclein Oligomers

细胞外伴侣与毒性 α-突触核蛋白寡聚体之间相互作用的单分子表征

CELL REPORTS

IF6.9

2018-06-0154

OAAI

The small heat shock protein Hsp27 binds α-synuclein fibrils, preventing elongation and cytotoxicity

小热休克蛋白Hsp27结合 α-突触核蛋白原纤维，防止伸长和细胞毒性

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2018-03-01107

OAAI

Dezerae Cox

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