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I

Ismael Compañón

Universidad de La Rioja
H指数:20
被引数:1,247

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Microbial binding module employs sophisticated clustered saccharide patches to selectively adhere to mucins

微生物结合模块采用复杂的聚集糖基斑片选择性地粘附于黏蛋白

Nature Communications
IF15.7
2025-10-130
OAAI
Thapakorn Jaroentomeechai; Billy Veloz; Cátia O. Soares; Felix Goerdeler; Ana Sofia Grosso; Christian Büll; Rebecca L. Miller; Sanae Furukawa; Irene Ginés-Alcober; Víctor Taleb; Pedro Merino; Mattia Ghirardello; Ismael Compañón; Helena Coelho; Jorge S. Dias; Renaud Vincentelli; Bernard Henrissat; Hiren Joshi; Henrik Clausen; Francisco Corzana; Filipa Marcelo; Ramon Hurtado-Guerrero; Yoshiki Narimatsu
Rational Design of Dual-Domain Binding Inhibitors for N-Acetylgalactosamine Transferase 2 with Improved Selectivity over the T1 and T3 Isoforms

N-乙酰半乳糖胺转移酶2双结构域结合抑制剂的合理设计，对T1和T3亚型具有更高的选择性

JACS AU
IF8.7
2024-09-110
OAAI
Companon, Ismael; Ballard, Collin J.; Lira-Navarrete, Erandi; Santos, Tanausu; Monaco, Serena; Munoz-Garcia, Juan C.; Delso, Ignacio; Angulo, Jesus; Gerken, Thomas A.; Schjoldager, Katrine T.; Clausen, Henrik; Tejero, Tomas; Merino, Pedro; Corzana, Francisco; Hurtado-Guerrero, Ramon; Ghirardello, Mattia
Structure-Guided Approach for the Development of MUC1-Glycopeptide-Based Cancer Vaccines with Predictable Responses
JACS AU
IF8.7
2023-11-214
OAAI
Bermejo, Iris A.; Guerreiro, Ana; Eguskiza, Ander; Martinez-Saez, Nuria; Lazaris, Foivos S.; Asin, Alicia; Somovilla, Victor J.; Companon, Ismael; Raju, Tom K.; Tadic, Srdan; Garrido, Pablo; Garcia-Sanmartin, Josune; Mangini, Vincenzo; Grosso, Ana S.; Marcelo, Filipa; Avenoza, Alberto; Busto, Jesus H.; Garcia-Martin, Fayna; Hurtado-Guerrero, Ramon; Peregrina, Jesus M.; Bernardes, Goncalo J. L.; Martinez, Alfredo; Fiammengo, Roberto; Corzana, Francisco
Structural and mechanistic insights into the cleavage of clustered O-glycan patches-containing glycoproteins by mucinases of the human gut

通过人类肠道的粘蛋白酶裂解含聚簇O-聚糖斑块的糖蛋白的结构和机理见解

NATURE COMMUNICATIONS
IF15.7
2022-07-2625
OAAI
Taleb, Victor; Liao, Qinghua; Narimatsu, Yoshiki; Garcia-Garcia, Ana; Companon, Ismael; Borges, Rafael Junqueira; Gonzalez-Ramirez, Andres Manuel; Corzana, Francisco; Clausen, Henrik; Rovira, Carme; Hurtado-Guerrero, Ramon
Single Mutation on Trastuzumab Modulates the Stability of Antibody-Drug Conjugates Built Using Acetal-Based Linkers and Thiol-Maleimide Chemistry
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
IF15.6
2022-03-1611
OAAI
Ferhati, Xhenti; Jimenez-Moreno, Ester; Hoyt, Emily A.; Salluce, Giulia; Cabeza-Cabrerizo, Mar; Navo, Claudio D.; Companon, Ismael; Akkapeddi, Padma; Matos, Maria J.; Salaverri, Noelia; Garrido, Pablo; Martinez, Alfredo; Laserna, Victor; Murray, Thomas, V; Jimenez-Oses, Gonzalo; Ravn, Peter; Bernardes, Goncalo J. L.; Corzana, Francisco
Atomic and Specificity Details of Mucin 1 O-Glycosylation Process by Multiple Polypeptide GalNAc-Transferase Isoforms Unveiled by NMR and Molecular Modeling

通过NMR和分子建模揭示了多种多肽GalNAc-转移酶同工型的粘蛋白1 O-糖基化过程的原子和特异性细节

JACS AU
IF8.7
2022-02-2415
OAAI
Coelho, Helena; de las Rivas, Matilde; Grosso, Ana S.; Diniz, Ana; Soares, Catia O.; Francisco, Rodrigo A.; Dias, Jorge S.; Companon, Ismael; Sun, Lingbo; Narimatsu, Yoshiki; Vakhrushev, Sergey Y.; Clausen, Henrik; Cabrita, Eurico J.; Jimenez-Barbero, Jesus; Corzana, Francisco; Hurtado-Guerrero, Ramon; Marcelo, Filipa
Molecular basis for fibroblast growth factor 23 O-glycosylation by GalNAc-T3

GalNAc-T3成纤维细胞生长因子23 O-糖基化的分子基础

NATURE CHEMICAL BIOLOGY
IF13.7
2020-01-1362
OAAI
de las Rivas, Matilde; Paul Daniel, Earnest James; Narimatsu, Yoshiki; Companon, Ismael; Kato, Kentaro; Hermosilla, Pablo; Thureau, Aurelien; Ceballos-Laita, Laura; Coelho, Helena; Bernado, Pau; Marcelo, Filipa; Hansen, Lars; Maeda, Ryota; Lostao, Anabel; Corzana, Francisco; Clausen, Henrik; Gerken, Thomas A.; Hurtado-Guerrero, Ramon
Quaternization of Vinyl/Alkynyl Pyridine Enables Ultrafast Cysteine-Selective Protein Modification and Charge Modulation

乙烯基/炔基吡啶的季铵化实现了超快的半胱氨酸选择性蛋白质修饰和电荷调节

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
IF16.9
2019-04-0959
OAAI
Matos, Maria J.; Navo, Claudio D.; Hakala, Tuuli; Ferhati, Xhenti; Guerreiro, Ana; Hartmann, David; Bernardim, Barbara; Saar, Kadi L.; Companon, Ismael; Corzana, Francisco; Knowles, Tuomas P. J.; Jimenez-Oses, Gonzalo; Bernardes, Goncalo J. L.
Structure-Based Design of Potent Tumor-Associated Antigens: Modulation of Peptide Presentation by Single-Atom O/S or O/Se Substitutions at the Glycosidic Linkage

有效的肿瘤相关抗原的基于结构的设计: 通过糖苷键上的单原子O/S或O/Se取代来调节肽的呈递

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
IF15.6
2019-02-0660
OAAI
Companon, Ismael; Guerreiro, Ana; Mangini, Vincenzo; Castro-Lopez, Jorge; Escudero-Casao, Margarita; Avenoza, Alberto; Busto, Jesus H.; Castillon, Sergio; Jimenez-Barbero, Jesus; Asensio, Juan L.; Jimenez-Oses, Gonzalo; Boutureira, Omar; Peregrina, Jesus M.; Hurtado-Guerrero, Ramon; Fiammengo, Roberto; Bernardes, Goncalo J. L.; Corzana, Francisco
Water Sculpts the Distinctive Shapes and Dynamics of the Tumor-Associated Carbohydrate Tn Antigens: Implications for Their Molecular Recognition
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
IF15.6
2018-07-1338
OAAI
Bermejo, Iris A.; Usabiaga, Imanol; Companon, Ismael; Castro-Lopez, Jorge; Insausti, Aran; Fernandez, Jose A.; Avenoza, Alberto; Busto, Jesus H.; Jimenez-Barbero, Jesus; Asensio, Juan L.; Peregrina, Jesus M.; Jimenez-Oses, Gonzalo; Hurtado-Guerrero, Ramon; Cocinero, Emilio J.; Corzana, Francisco

研究方向

暂未获取到该数据
F
Francisco Corzana
H 指数:45论文数:290被引数:5,760
R
Ramón Hurtado‐Guerrero
H 指数:40论文数:224被引数:4,135
J
Jesús M. Peregrina
H 指数:34论文数:314被引数:3,756
H
Henrik Clausen
H 指数:113论文数:639被引数:5.7万
G
Gonçalo J. L. Bernardes
H 指数:65论文数:368被引数:1.7万
J
Jesús H. Busto
H 指数:29论文数:192被引数:2,705
A
Alberto Avenoza
H 指数:32论文数:309被引数:3,489
F
Filipa Marcelo
H 指数:27论文数:108被引数:2,262
J
Jesús Jiménez‐Barbero
H 指数:79论文数:914被引数:2.6万
H
Helena Coelho
H 指数:17论文数:37被引数:838