Alexander Apt - Publications, H-index & Citations

Alexander Apt

central research tuberculosis institute

33H指数

184论文数

3.3K被引数

收录论文 19

发表时间

Susceptibility to and severity of tuberculosis infection in mice depends upon MHC-II-determined level of activation-inhibition balance in CD4 T-cells 小鼠对结核分枝杆菌感染的易感性和严重程度取决于由MHC-II决定的CD4 T细胞激活-抑制平衡水平。

Frontiers in Immunology

IF5.9

2025-08-12

OAAI

Nadezhda Logunova; Marina Kapina; Valeriia Kriukova; Olga Britanova; Konstantin Majorov; Irina Linge; Alexander Apt

Aberrant adaptive immune response underlies genetic susceptibility to tuberculosis

FRONTIERS IN IMMUNOLOGY

IF5.9

2024-05-10

OAAI

Tsareva, Anastasiia; Shelyakin, Pavel V.; Shagina, Irina A.; Myshkin, Mikhail Yu.; Merzlyak, Ekaterina M.; Kriukova, Valeriia V.; Apt, Alexander S.; Linge, Irina A.; Chudakov, Dmitriy M.; Britanova, Olga V.

Acquiring of photosensitivity by Mycobacterium tuberculosis in vitro and inside infected macrophages is associated with accumulation of endogenous Zn-porphyrins

SCIENTIFIC REPORTS

IF3.9

2024-01-08

OAAI

Shleeva, Margarita O.; Linge, Irina A.; Gligonov, Ivan A.; Vostroknutova, Galina N.; Shashin, Denis M.; Tsedilin, Andrey M.; Apt, Alexander S.; Kaprelyants, Arseny S.; Savitsky, Alexander P.

The H2-A Class II molecule α/β-chain cis-mismatch severely affects cell surface expression, selection of conventional CD4+ T cells and protection against TB infection

FRONTIERS IN IMMUNOLOGY

IF5.9

2023-06-22

OAAI

Logunova, Nadezhda; Kapina, Marina; Kondratieva, Elena; Apt, Alexander

Penetration of Triphenylphosphonium Derivatives through the Cell Envelope of Bacteria of Mycobacteriales Order

PHARMACEUTICALS

IF4.8

2023-05-02

OAAI

Nazarov, Pavel A.; Majorov, Konstantin B.; Apt, Alexander S.; Skulachev, Maxim V.

Pleiotropic Effect of IL-6 Produced by B-Lymphocytes During Early Phases of Adaptive Immune Responses Against TB Infection

FRONTIERS IN IMMUNOLOGY

IF5.9

2022-01-27

OAAI

Linge, Irina; Tsareva, Anastasiya; Kondratieva, Elena; Dyatlov, Alexander; Hidalgo, Juan; Zvartsev, Ruslan; Apt, Alexander

Gausemycins A,B: Cyclic Lipoglycopeptides from Streptomyces sp.**

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

IF16.9

2021-06-22

PREAI

Tyurin, Anton P.; Alferova, Vera A.; Paramonov, Alexander S.; Shuvalov, Maxim V.; Kudryakova, Gulnara K.; Rogozhin, Eugene A.; Zherebker, Alexander Y.; Brylev, Vladimir A.; Chistov, Alexey A.; Baranova, Anna A.; Biryukov, Mikhail V.; Ivanov, Igor A.; Prokhorenko, Igor A.; Grammatikova, Natalia E.; Kravchenko, Tatyana V.; Isakova, Elena B.; Mirchink, Elena P.; Gladkikh, Elena G.; Svirshchevskaya, Elena V.; Mardanov, Andrey V.; Beletsky, Aleksey V.; Kocharovskaya, Milita V.; Kulyaeva, Valeriya V.; Shashkov, Alexander S.; Tsvetkov, Dmitry E.; Nifantiev, Nikolay E.; Apt, Alexander S.; Majorov, Konstantin B.; Efimova, Svetlana S.; Ravin, Nikolai V.; Nikolaev, Evgeny N.; Ostroumova, Olga S.; Katrukha, Genrikh S.; Lapchinskaya, Olda A.; Dontsova, Olga A.; Terekhov, Stanislav S.; Osterman, Ilya A.; Shenkarev, Zakhar O.; Korshun, Vladimir A.

Structural Modifications of 3-Triazeneindoles and Their Increased Activity AgainstMycobacterium tuberculosis

ANTIBIOTICS-BASEL

IF4.6

2020-06-24

OAAI

Majorov, Konstantin B.; Nikonenko, Boris, V; Ivanov, Pavel Yu; Telegina, Lyudmila N.; Apt, Alexander S.; Velezheva, Valeria S.

MHC-II alleles shape the CDR3 repertoires of conventional and regulatory naive CD4+ T cells Mhc-ii等位基因塑造了常规和调节性幼稚CD4 T细胞的CDR3库

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2020-06-01

OAAI

Logunova, Nadezhda N.; Kriukova, Valeriia V.; Shelyakin, Pavel V.; Egorov, Evgeny S.; Pereverzeva, Alina; Bozhanova, Nina G.; Shugay, Mikhail; Shcherbinin, Dmitrii S.; Pogorelyy, Mikhail V.; Merzlyak, Ekaterina M.; Zubov, Vasiliy N.; Meiler, Jens; Chudakov, Dmitriy M.; Apt, Alexander S.; Britanova, Olga V.

Efficacy of anti-tuberculosis therapy with INH, RIF and Bedaquiline in mice with different genetic susceptibility to the infection

EUROPEAN RESPIRATORY JOURNAL

IF21

2019-11-21

PREAI

Nikonenko, Boris; Bocharova, Irina; Korotetskaya, Maria; Kondratieva, Elena; Apt, Alexander

New inbred mouse strains for the studying M. tuberculosis - host interactions

EUROPEAN RESPIRATORY JOURNAL

IF21

2018-11-19

PREAI

Nikonenko, Boris; Logunova, Nadezhda; Bocharova, Irina; Apt, Alexander

In Vitro Activity of 3-Triazeneindoles against Mycobacterium tuberculosis and Mycobacterium avium

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

IF4.5

2016-10-01

OAAI

Nikonenko, Boris V.; Kornienko, Albert; Majorov, Konstantin; Ivanov, Pavel; Kondratieva, Tatiana; Korotetskaya, Maria; Apt, Alexander S.; Salina, Elena; Velezheva, Valeriya

Therapeutic Effect of Recombinant Mutated Interleukin 11 in the Mouse Model of Tuberculosis

JOURNAL OF INFECTIOUS DISEASES

IF4.5

2016-05-13

OAAI

Shepelkova, Galina; Evstifeev, Vladimir; Majorov, Konstantin; Bocharova, Irina; Apt, Alexander

The QTL within the H2 Complex Involved in the Control of Tuberculosis Infection in Mice Is the Classical Class II H2-Ab1 Gene

PLOS GENETICS

IF3.7

2015-11-30

OAAI

Logunova, Nadezhda; Korotetskaya, Maria; Polshakov, Vladimir; Apt, Alexander

Reactivation of dormant non-culturable Mycobacterium tuberculosis developed in vitro after injection in mice: Both the dormancy depth and host genetics influence the outcome

MICROBIAL PATHOGENESIS

IF3.5

2015-01-01

PREAI

Shleeva, Margarita; Kondratieva, Tatiana; Rubakova, Elvira; Vostroknutova, Galina; Kaprelyants, Arseny; Apt, Alexander

B Cells Delay Neutrophil Migration toward the Site of Stimulus: Tardiness Critical for Effective Bacillus Calmette-Guerin Vaccination against Tuberculosis Infection in Mice

JOURNAL OF IMMUNOLOGY

IF3.4

2009-12-18

OAAI

Kondratieva, Tatiana K.; Rubakova, Elvira I.; Linge, Irina A.; Evstifeev, Vladimir V.; Majorov, Konstantin B.; Apt, Alexander S.

CD27low CD4 T lymphocytes that accumulate in the mouse lungs during mycobacterial infection differentiate from CD27high precursors in situ, produce IFN-γ, and protect the host against tuberculosis infection

JOURNAL OF IMMUNOLOGY

IF3.4

2007-01-15

OAAI

Kapina, Marina A.; Shepelkova, Galina S.; Mischenko, Vladimir V.; Sayles, Peter; Bogacheva, Polina; Winslow, Gary; Apt, Alexander S.; Lyadova, Irina V.

Mycobacterium tuberculosis-susceptible I/St mice develop severe disease following infection with taxonomically distant bacteria, Salmonella enterica and Chlamydia pneumoniae

CLINICAL AND EXPERIMENTAL IMMUNOLOGY

IF3.8

2006-08-31

OAAI

Nesterenko, L. N.; Balunets, D. V.; Tomova, A. S.; Romanova, J. M.; Alyapkina, J. S.; Zigangirova, N. A.; Kapina, M. A.; Kondratieva, E. V.; Pichugin, A. V.; Majorov, K. B.; Apt, A. S.

H2 complex controls CD4/CD8 ratio, recurrent responsiveness to repeated stimulations, and resistance to activation-induced apoptosis during T cell response to mycobacterial antigens

JOURNAL OF LEUKOCYTE BIOLOGY

IF3.1

2006-01-13

PREAI

Pichugin, Alexander V.; Petrovskaya, Svetlana N.; Apt, Alexander S.

研究方向