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Structure and dynamics determine G protein coupling specificity at a class A GPCR 结构和动力学决定了a类GPCR的g蛋白偶联特异性 Casiraghi, Marina; Wang, Haoqing; Brennan, Patrick C.; Habrian, Chris; Huebner, Harald; Schmidt, Maximilian F.; Maul, Luis; Pani, Biswaranjan; Bahriz, Sherif M. F. M.; Xu, Bing; Staffen, Nico; Assafa, Tufa E.; Chen, Bohan; White, Elizabeth; Sunahara, Roger K.; Inoue, Asuka; Xiang, Yang K.; Lefkowitz, Robert J.; Isacoff, Ehud Y.; Nucci, Nathaniel; Lerch, Michael T.; Kobilka, Brian K. 分享 收藏
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Discovery of VH domains that allosterically inhibit ENPP1 Solomon, Paige E.; Bracken, Colton J.; Carozza, Jacqueline A.; Wang, Haoqing; Young, Elizabeth P.; Wellner, Alon; Liu, Chang C.; Sweet-Cordero, E. Alejandro; Li, Lingyin; Wells, James A. 分享 收藏
Structure based approaches on fentanyl template to design novel mu opioid modulators 基于结构的芬太尼模板设计新型 μ 阿片调节剂 Ople, Rohini; Wang, Haoqing; Li, Qiongyu; Polacco, Ben; Bernhard, Sarah; Appourchaux, Kevin; Sribhashyam, Sashrik; Eans, Shainnel; Huttenhain, Ruth; McLaughlin, Jay; Kobilka, Brian; Majumdar, Susruta 分享 收藏
Structural and dynamic insights into supra-physiological activation and allosteric modulation of a muscarinic acetylcholine receptor 毒蕈碱乙酰胆碱受体的超生理激活和变构调节的结构和动态见解 Xu, Jun; Wang, Qinggong; Huebner, Harald; Hu, Yunfei; Niu, Xiaogang; Wang, Haoqing; Maeda, Shoji; Inoue, Asuka; Tao, Yuyong; Gmeiner, Peter; Du, Yang; Jin, Changwen; Kobilka, Brian K. 分享 收藏
Insights into distinct signaling profiles of the μOR activated by diverse agonists 洞察不同激动剂激活的 μ or的不同信号特征 Qu, Qianhui; Huang, Weijiao; Aydin, Deniz; Paggi, Joseph M.; Seven, Alpay B.; Wang, Haoqing; Chakraborty, Soumen; Che, Tao; DiBerto, Jeffrey F.; Robertson, Michael J.; Inoue, Asuka; Suomivuori, Carl-Mikael; Roth, Bryan L.; Majumdar, Susruta; Dror, Ron O.; Kobilka, Brian K.; Skiniotis, Georgios 分享 收藏
3,4-Bis(hydroxymethyl)hexane-1,6-diol-based Maltosides (HDMs) for Membrane-Protein Study: Importance of Detergent Rigidity-Flexibility Balance in Protein Stability Lee, Hyun Sung; Das, Manabendra; Mahler, Florian; Ahmed, Waqar; Wang, Haoqing; Mortensen, Jonas S.; Hariharan, Parameswaran; Ghani, Lubna; Byrne, Bernadette; Guan, Lan; Loland, Claus J.; Keller, Sandro; Chae, Pil Seok 分享 收藏
Structure-Based Evolution of G Protein-Biased μ-Opioid Receptor Agonists G蛋白偏向的 μ 阿片受体激动剂的基于结构的进化 Wang, Haoqing; Hetzer, Florian; Huang, Weijiao; Qu, Qianhui; Meyerowitz, Justin; Kaindl, Jonas; Huebner, Harald; Skiniotis, Georgios; Kobilka, Brian K.; Gmeiner, Peter 分享 收藏
Foldable Detergents for Membrane Protein Study: Importance of Detergent Core Flexibility in Protein Stabilization Ghani, Lubna; Kim, Seonghoon; Wang, Haoqing; Lee, Hyun Sung; Mortensen, Jonas S.; Katsube, Satoshi; Du, Yang; Sadaf, Aiman; Ahmed, Waqar; Byrne, Bernadette; Guan, Lan; Loland, Claus J.; Kobilka, Brian K.; Im, Wonpil; Chae, Pil Seok 分享 收藏
Development of 1,3-acetonedicarboxylate-derived glucoside amphiphiles (ACAs) for membrane protein study Lee, Ho Jin; Ehsan, Muhammad; Zhang, Xiang; Katsube, Satoshi; Munk, Chastine F.; Wang, Haoqing; Ahmed, Waqar; Kumar, Ashwani; Byrne, Bernadette; Loland, Claus J.; Guan, Lan; Liu, Xiangyu; Chae, Pil Seok 分享 收藏
Sequential immunization of macaques elicits heterologous neutralizing antibodies targeting the V3-glycan patch of HIV-1 Env Escolano, Amelia; Gristick, Harry B.; Gautam, Rajeev; DeLaitsch, Andrew T.; Abernathy, Morgan E.; Yang, Zhi; Wang, Haoqing; Hoffmann, Magnus A. G.; Nishimura, Yoshiaki; Wang, Zijun; Koranda, Nicholas; Kakutani, Leesa M.; Gao, Han; Gnanapragasam, Priyanthi N. P.; Raina, Henna; Gazumyan, Ana; Cipolla, Melissa; Oliveira, Thiago Y.; Ramos, Victor; Irvine, Darrell J.; Silva, Murillo; West, Anthony P., Jr.; Keeffe, Jennifer R.; Barnes, Christopher O.; Seaman, Michael S.; Nussenzweig, Michel C.; Martin, Malcolm A.; Bjorkman, Pamela J. 分享 收藏
Maltose-bis(hydroxymethyl)phenol (MBPs) and Maltosetris(hydroxymethyl)phenol (MTPs) Amphiphiles for Membrane Protein Stability Ehsan, Muhammad; Wang, Haoqing; Cecchetti, Cristina; Mortensen, Jonas S.; Du, Yang; Hariharan, Parameswaran; Nygaard, Andreas; Lee, Ho Jin; Ghani, Lubna; Guan, Lan; Loland, Claus J.; Byrne, Bernadette; Kobilka, Brian K.; Chae, Pil Seok 分享 收藏
Conformationally flexible core-bearing detergents with a hydrophobic or hydrophilic pendant: Effect of pendant polarity on detergent conformation and membrane protein stability Sadaf, Aiman; Kim, Seonghoon; Bae, Hyoung Eun; Wang, Haoqing; Nygaard, Andreas; Uegaki, Yuki; Du, Yang; Munk, Chastine F.; Katsube, Satoshi; Lee, Hyun Sung; Bae, Jungnam; Choi, Chul Won; Choi, Hee-Jung; Byrne, Bernadette; Gellman, Samuel H.; Guan, Lan; Loland, Claus J.; Kobilka, Brian K.; Im, Wonpil; Chae, Pil Seok 分享 收藏
Diastereomeric Cyclopentane-Based Maltosides (CPMs) as Tools for Membrane Protein Study Das, Manabendra; Mahler, Florian; Hariharan, Parameswaran; Wang, Haoqing; Du, Yang; Mortensen, Jonas S.; Patallo, Eugenio Perez; Ghani, Lubna; Glueck, David; Lee, Ho Jin; Byrne, Bernadette; Loland, Claus J.; Guan, Lan; Kobilka, Brian K.; Keller, Sandro; Chae, Pil Seok 分享 收藏
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New Malonate-Derived Tetraglucoside Detergents for Membrane Protein Stability Ehsan, Muhammad; Katsube, Satoshi; Cecchetti, Cristina; Du, Yang; Mortensen, Jonas S.; Wang, Haoqing; Nygaard, Andreas; Ghani, Lubna; Loland, Claus Juul; Kobilka, Brian K.; Byrne, Bernadette; Guan, Lan; Chae, Pil Seok 分享 收藏
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