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Targeting modulated vascular smooth muscle cells in atherosclerosis via FAP-directed immunotherapy Amrute, J.M.; Jung, I.H.; Yamawaki, T.; Lin, W.L.; Bredemeyer, A.; Diekmann, J.; Hayat, S.; Zhang, X.; Wakefield, D.L.; Luo, X.; et al. 通过FAP定向免疫疗法靶向调节动脉粥样硬化中的血管平滑肌细胞。Science 2026, eadx1736. [Google Scholar] [CrossRef] Junedh M. Amrute; In-Hyuk Jung; Tracy Yamawaki; Wen-Ling Lin; Andrea Bredemeyer; Johanna Diekmann; Sikander Hayat; Xianglong Zhang; Devin L. Wakefield; Xin Luo; Sidrah Maryam; Gyu Seong Heo; Steven Yang; Chang Jie Mick Lee; Chen Wang; Caroline Chou; Christoph Kuppe; Kevin D. Cook; Atilla Kovacs; Vishnu Chintalgattu; Danielle Pruitt; Jose Barreda; Nathan O. Stitziel; Paul Cheng; Yongjian Liu; Rafael Kramann; Daniel Kreisel; Roger S.-Y. Foo; Ingrid C. Rulifson; Scott Martin; David Grunert; Melissa Thomas; Jixin Cui; Thomas Quertermous; Frank M. Bengel; Simon Jackson; Chi-Ming Li; Brandon Ason; Kory J. Lavine 分享 收藏
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Tissue-resident CCR2+macrophage TREM-1/3 signaling is necessary for monocyte and neutrophil recruitment to injured hearts 组织驻留CCR2+ 巨噬细胞TREM-1/3信号对于单核细胞和中性粒细胞的募集至受损心脏是必需的 Terada, Yuriko; Li, Wenjun; Amrute, Junedh M.; Bery, Amit I.; Liu, Charles R.; Nunna, Venkatrao; Frye, Christian Corbin; Dun, Hao; Koenig, Andrew L.; Luehmann, Hannah P.; Heo, Gyu Seong; Owen, Macee C.; Wein, Alexander N.; Liu, Yongjian; Ritter, Jon H.; Prabhu, Sumanth D.; Nava, Ruben G.; Gelman, Andrew E.; Cella, Marina; Colonna, Marco; Lavine, Kory J.; Kreisel, Daniel 分享 收藏
Molecular imaging in experimental pulmonary fi brosis reveals that nintedanib unexpectedly modulates CCR2 immune cell infiltration Farooq, Hasan; Luehmann, Hannah P.; Koenitzer, Jeffrey R.; Heo, Gyu Seong; Sultan, Deborah H.; Kulkarni, Devesha H.; Gunsten, Sean P.; Sashti, Rekha M.; Huang, Tao; Keller, Amanda R.; Lavine, Kory J.; Atkinson, Jeffrey J.; Wingler, Laura M.; Liu, Yongjian; Brody, Steven L. 分享 收藏
Molecular imaging of macrophage composition and dynamics in MASLD Yang, Bin Q.; Chan, Mandy M.; Heo, Gyu Seong; Lou, Lanlan; Luehmann, Hannah; Park, Christopher; Li, Alexandria; Lahad, Divangana; Sultan, Deborah; Voller, Peter; Byrnes, Kathleen; Fu, Christina; Liu, Yongjian; Schilling, Joel D. 分享 收藏
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Visualizing Immune Checkpoint Inhibitors Derived Inflammation in Atherosclerosis Lou, Lanlan; Detering, Lisa; Luehmann, Hannah; Amrute, Junedh M.; Sultan, Deborah; Ma, Pan; Li, Alexandria; Lahad, Divangana; Bredemeyer, Andrea; Zhang, Xiuli; Heo, Gyu Seong; Lavine, Kory; Liu, Yongjian 分享 收藏
Glucose metabolism controls monocyte homeostasis and migration but has no impact on atherosclerosis development in mice Gallerand, Alexandre; Dolfi, Bastien; Stunault, Marion I.; Caillot, Zakariya; Castiglione, Alexia; Strazzulla, Axelle; Chen, Chuqiao; Heo, Gyu Seong; Luehmann, Hannah; Batoul, Flora; Vaillant, Nathalie; Dumont, Adelie; Pilot, Thomas; Merlin, Johanna; Zair, Fairouz N.; Gilleron, Jerome; Bertola, Adeline; Carmeliet, Peter; Williams, Jesse W.; Arguello, Rafael J.; Masson, David; Dombrowicz, David; Yvan-Charvet, Laurent; Doyen, Denis; Haschemi, Arvand; Liu, Yongjian; Guinamard, Rodolphe R.; Ivanov, Stoyan 分享 收藏
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Development of a CD163-Targeted PET Radiotracer That Images Resident Macrophages in Atherosclerosis Zhang, Xiuli; Heo, Gyu Seong; Li, Alexandria; Lahad, Divangana; Detering, Lisa; Tao, Joan; Gao, Xuefeng; Zhang, Xiaohui; Luehmann, Hannah; Sultan, Deborah; Lou, Lanlan; Venkatesan, Rajiu; Li, Ran; Zheng, Jie; Amrute, Junedh; Lin, Chieh-Yu; Kopecky, Benjamin J.; Gropler, Robert J.; Bredemeyer, Andrea; Lavine, Kory; Liu, Yongjian 分享 收藏
Development of a CCR2 targeted 18F-labeled radiotracer for atherosclerosis imaging with PET Zhang, Xiaohui; Qiu, Lin; Sultan, Debbie H.; Luehmann, Hannah P.; Yu, Yanbo; Zhang, Xiuli; Heo, Gyu Seong; Li, Alexandria; Lahad, Divangana; Rho, Shinji; Tu, Zhude; Liu, Yongjian 分享 收藏
Ketosis prevents abdominal aortic aneurysm rupture through C-C chemokine receptor type 2 downregulation and enhanced extracellular matrix balance Sastriques-Dunlop, Sergio; Elizondo-Benedetto, Santiago; Arif, Batool; Meade, Rodrigo; Zaghloul, Mohamed S.; Luehmann, Hannah; Heo, Gyu S.; English, Sean J.; Liu, Yongjian; Zayed, Mohamed A. 分享 收藏
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Expansion of Pathogenic Cardiac Macrophages in Immune Checkpoint Inhibitor Myocarditis 免疫检查点抑制剂心肌炎中致病性心脏巨噬细胞的扩增 Ma, Pan; Liu, Jing; Qin, Juan; Lai, Lulu; Heo, Gyu Seong; Luehmann, Hannah; Sultan, Deborah; Bredemeyer, Andrea; Bajapa, Geetika; Feng, Guoshuai; Jimenez, Jesus; He, Ruijun; Parks, Antanisha; Amrute, Junedh; Villanueva, Ana; Liu, Yongjian; Lin, Chieh-Yu; Mack, Matthias; Amancherla, Kaushik; Moslehi, Javid; Lavine, Kory J. 分享 收藏
CCR2 imaging in human ST-segment elevation myocardial infarction Lavine, Kory J.; Sultan, Deborah; Luehmann, Hannah; Detering, Lisa; Zhang, Xiaohui; Heo, Gyu Seong; Zhang, Xiuli; Hoelscher, Michelle; Harrison, Kitty; Combadiere, Christophe; Laforest, Richard; Kreisel, Daniel; Woodard, Pamela K.; Brody, Steven L.; Gropler, Robert J.; Liu, Yongjian 分享 收藏
Multiparametric Immunoimaging Maps Inflammatory Signatures in Murine Myocardial Infarction Models Maier, Alexander; Toner, Yohana C.; Munitz, Jazz; Sullivan, Nathaniel A. T.; Sakurai, Ken; Meerwaldt, Anu E.; Brechbuhl, Eliane E. S.; Prevot, Geoffrey; van Elsas, Yuri; Maas, Rianne J. F.; Ranzenigo, Anna; Soultanidis, Georgios; Rashidian, Mohammad; Perez-Medina, Carlos; Heo, Gyu Seong; Gropler, Robert J.; Liu, Yongjian; Reiner, Thomas; Nahrendorf, Matthias; Swirski, Filip K.; Strijkers, Gustav J.; Teunissen, Abraham J. P.; Calcagno, Claudia; Fayad, Zahi A.; Mulder, Willem J. M.; van Leent, Mandy M. T. 分享 收藏
Ccr2 Inhibition Impacts Abdominal Aortic Aneurysm Rupture In Rodents Zaghloul, Mohamed S.; Elizondo-Benedetto, Santiago; Arif, Batool; Detering, Lisa; Luehmann, Hannah; Sultan, Debbie; Heo, Gyu Seong; Gropler, Robert J.; Liu, Yongjian; Zayed, Mohamed A. 分享 收藏
Reprogramming alveolar macrophage responses to TGF-β reveals CCR2+ monocyte activity that promotes bronchiolitis obliterans syndrome Liu, Zhiyi; Liao, Fuyi; Zhu, Jihong; Zhou, Dequan; Heo, Gyu Seong; Leuhmann, Hannah P.; Scozzi, Davide; Parks, Antanisha; Hachem, Ramsey; Byers, Derek E.; Tague, Laneshia K.; Kulkarni, Hrishikesh S.; Cano, Marlene; Wong, Brian W.; Li, Wenjun; Huang, Howard J.; Krupnick, Alexander S.; Kreisel, Daniel; Liu, Yongjian; Gelman, Andrew E. 分享 收藏
A Long-Circulating Vector for Aptamers Based upon Polyphosphodiester-Backboned Molecular Brushes Wang, Yuyan; Wang, Dali; Lin, Jiachen; Lyu, Zidi; Chen, Peiru; Sun, Tingyu; Xue, Chenyang; Mojtabavi, Mehrnaz; Vedadghavami, Armin; Zhang, Zheyu; Wang, Ruimeng; Zhang, Lei; Park, Christopher; Heo, Gyu Seong; Liu, Yongjian; Dong, Sijia; Zhang, Ke 分享 收藏
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