Discovery of the First Selective Nanomolar Inhibitors of ERAP2 by Kinetic Target-Guided SynthesisANGEWANDTE CHEMIE-INTERNATIONAL EDITIONIF16.92022-08-199OA
Structural Insights into the Role of β3 nAChR Subunit in the Activation of Nicotinic ReceptorsMOLECULESIF4.62022-07-201OAAI
Discovery of Selective Nanomolar Inhibitors for Insulin-Regulated Aminopeptidase Based on α-Hydroxy-β-amino Acid Derivatives of BestatinJOURNAL OF MEDICINAL CHEMISTRYIF6.82022-07-1410OA
Inhibitor-Dependent Usage of the S1′ Specificity Pocket of ER Aminopeptidase 2ACS MEDICINAL CHEMISTRY LETTERSIF42022-01-132OA
Insights into the Protein Ruthenation Mechanism by Antimetastatic Metallodrugs: High-Resolution X-ray Structures of the Adduct Formed between Hen Egg-White Lysozyme and NAMI-A at Various Time PointsINORGANIC CHEMISTRYIF4.72021-07-017PREAI
Structural Basis of Inhibition of Insulin-Regulated Aminopeptidase by a Macrocyclic Peptidic Inhibitor大环肽抑制剂抑制胰岛素调节的氨肽酶的结构基础ACS MEDICINAL CHEMISTRY LETTERSIF42020-06-0220OAAI
Mechanism for antigenic peptide selection by endoplasmic reticulum aminopeptidase 1PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICAIF9.12019-12-1640OAAI
High-Resolution Crystal Structure of Endoplasmic Reticulum Aminopeptidase 1 with Bound Phosphinic Transition-State Analogue InhibitorACS MEDICINAL CHEMISTRY LETTERSIF42019-02-1331OAAI
Understanding structure-function relationships of the human neuronal acetylcholine receptor: insights from the first crystal structures of neuronal subunitsBRITISH JOURNAL OF PHARMACOLOGYIF7.72017-06-2026OAAI
Ligand-Induced Conformational Change of Insulin-Regulated Aminopeptidase: Insights on Catalytic Mechanism and Active Site PlasticityJOURNAL OF MEDICINAL CHEMISTRYIF6.82017-04-0335OAAI
Crystal Structures of ERAP2 Complexed with Inhibitors Reveal Pharmacophore Requirements for Optimizing Inhibitor PotencyACS MEDICINAL CHEMISTRY LETTERSIF42017-02-2417OAAI
Crystal structure of a human neuronal nAChR extracellular domain in pentameric assembly: Ligand-bound α2 homopentamerPROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICAIF9.12016-08-0449OAAI
Formation of a highly-ordered rigid multichromophoric 3D supramolecular network by combining ionic and coordination-driven self-assemblyCHEMICAL COMMUNICATIONSIF4.22016-01-0120PREAI
Structural Basis for Antigenic Peptide Recognition and Processing by Endoplasmic Reticulum (ER) Aminopeptidase 2JOURNAL OF BIOLOGICAL CHEMISTRYIF3.92015-10-0169OAAI
Two Putative Polysaccharide Deacetylases Are Required for Osmotic Stability and Cell Shape Maintenance in Bacillus anthracisJOURNAL OF BIOLOGICAL CHEMISTRYIF3.92015-05-0127OAAI
Molecular Interaction of α-Conotoxin RgIA with the Rat α9α10 Nicotinic Acetylcholine ReceptorMOLECULAR PHARMACOLOGYIF32015-05-0151OAAI
Crystal structures of free and antagonist-bound states of human α9 nicotinic receptor extracellular domainNATURE STRUCTURAL & MOLECULAR BIOLOGYIF10.12014-10-0591PREAI
Non-contact Current Transfer Induces the Formation and Improves the X-ray Diffraction Quality of Protein CrystalsCRYSTAL GROWTH & DESIGNIF3.42014-08-181PREAI
Expression of human AChR extracellular domain mutants with improved characteristicsINTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULESIF8.52014-02-0113PREAI
A Common Single Nucleotide Polymorphism in Endoplasmic Reticulum Aminopeptidase 2 Induces a Specificity Switch That Leads to Altered Antigen ProcessingJOURNAL OF IMMUNOLOGYIF3.42012-09-0189OA