Russell D. Lewis - Publications, H-index & Citations

Russell D. Lewis

pfizer

14H指数

29论文数

2.0K被引数

收录论文 17

发表时间

Data Driven Discovery of Reductive Aminases for Arylamine Substrates 基于数据的还原性氨酶的发现：用于芳胺底物

ADVANCED SYNTHESIS & CATALYSIS

IF4

2026-05-21

PREAI

Caroline K. Brennan; Miguel A. Abdo; Robert A. Scism; Liu Cao; Carlos A. Martinez; Russell D. Lewis

Dietary exposure to hexafluoropropylene oxide dimer acid (HFPO-DA ammonium salt, GenX) alters hepatic sphingomyelin and phosphatidylcholine metabolism in Nile Tilapia (Oreochromis niloticus)膳食暴露于六氟丙烯氧化物二聚酸（HFPO-DA铵盐，GenX）会改变尼罗罗非鱼（Oreochromis niloticus）的肝组织鞘磷脂和磷脂酰胆碱代谢。

Aquatic Toxicology

IF4.3

2025-09-24

PREAI

Amany Sultan; Isaac Konig; Adam Point; Victor Hugo Buttrós; Russell Lewis; Denina Simmons; Christopher J. Martyniuk

Structures of “Tyrosine-IRED” IR91 from Kribbella flavida in Complex with a Reductive Amination Substrate and Product 黄原葵黄杆菌（Kribbella flavida）来源的“酪氨酸-IRED” IR91与还原性胺化底物和产物的复合物结构

ChemBioChem

IF2.8

2025-07-29

PREAI

Krishnan Srinivas; Amelia K. Gilio; Mahima Sharma; Lawrence Green; Alexander Ascham; Jack Domenech; Balázs Pogrányi; Jiacheng Li; Scott P. France; Russell D. Lewis; William P. Unsworth; Gideon Grogan

Ancestral Sequence Reconstruction Meets Machine Learning: Ene Reductase Thermostabilization Yields Enzymes with Improved Reactivity Profiles

ACS CATALYSIS

IF13.1

2024-11-20

PREAI

Brennan, Caroline K.; Livada, Jovan; Martinez, Carlos A.; Lewis, Russell D.

Development of the Synthetic Route to PF-06878031 Part 2: Amide Reduction Route

ORGANIC PROCESS RESEARCH & DEVELOPMENT

IF3.5

2024-04-19

PREAI

Brown, Maria S.; Buck, Julia; Critcher, Douglas J.; Derrick, Andrew M.; Fenton, Harriet; Fussell, Steven J.; Gymer, Adam E. S.; Hawksworth, Michael; Ingram, Heather; Johnson, Rebecca A.; Kumar, Rajesh; Laity, Daniel A.; Lewis, Russell D.; Mathew, Jinu S.; McGivern, Laura; Moses, Ian B.; Palaia, Andrew T.; Patel, Miheal J.; Rellegue, James; Rose, Emily K.; Scott, Adam; Steflik, Jeremy; Twiddle, Steven J. R.

Engineering of a Reductive Aminase to Enable the Synthesis of a Key Intermediate to a CDK 2/4/6 Inhibitor

ACS CATALYSIS

IF13.1

2023-07-18

OAAI

Steflik, Jeremy; Gilio, Amelia; Burns, Michael; Grogan, Gideon; Kumar, Rajesh; Lewis, Russell; Martinez, Carlos

Emerging Technologies for Biocatalysis in the Pharmaceutical Industry

ACS CATALYSIS

IF13.1

2023-04-10

OAAI

Lewis, Russell D.; France, Scott P.; Martinez, Carlos A.

The Evolving Nature of Biocatalysis in Pharmaceutical Research and Development

JACS AU

IF8.7

2023-02-27

OAAI

France, Scott P.; Lewis, Russell D.; Martinez, Carlos A.

Ancestral Sequence Reconstruction Enhances Gene Mining Efforts for Industrial Ene Reductases by Expanding Enzyme Panels with Thermostable Catalysts

ACS CATALYSIS

IF13.1

2023-02-06

PREAI

Livada, Jovan; Vargas, Ariana M.; Martinez, Carlos A.; Lewis, Russell D.

A Reductive Aminase Switches to Imine Reductase Mode for a Bulky Amine Substrate 对于庞大的胺底物，还原性转氨酶转换为亚胺还原酶模式

ACS CATALYSIS

IF13.1

2023-01-12

OAAI

Gilio, Amelia K.; Thorpe, Thomas W.; Heyam, Alex; Petchey, Mark R.; Pogranyi, Balazs; France, Scott P.; Howard, Roger M.; Karmilowicz, Michael J.; Lewis, Russell; Turner, Nicholas; Grogan, Gideon

The Single-Component Flavin Reductase/Flavin-Dependent Halogenase AetF is a Versatile Catalyst for Selective Bromination and Iodination of Arenes and Olefins 单组分黄素还原酶/黄素依赖性卤化酶AetF是用于芳烃和烯烃的选择性溴化和碘化的通用催化剂

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

IF16.9

2022-11-22

OAAI

Jiang, Yuhua; Snodgrass, Harrison M.; Zubi, Yasmine S.; Roof, Caitlin V.; Guan, Yanfei; Mondal, Dibyendu; Honeycutt, Nicholas H.; Lee, Johnny W.; Lewis, Russell D.; Martinez, Carlos A.; Lewis, Jared C.

Origin and Control of Chemoselectivity in Cytochrome c Catalyzed Carbene Transfer into Si-H and N-H bonds

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

IF15.6

2021-04-28

OAAI

Garcia-Borras, Marc; Kan, S. B. Jennifer; Lewis, Russell D.; Tang, Allison; Jimenez-Oses, Gonzalo; Arnold, Frances H.; Houk, K. N.

Machine learning-assisted directed protein evolution with combinatorial libraries 机器学习辅助的定向蛋白质进化与组合库

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2019-04-12

386

OAAI

Wu, Zachary; Kan, S. B. Jennifer; Lewis, Russell D.; Wittmann, Bruce J.; Arnold, Frances H.

Catalytic iron-carbene intermediate revealed in a cytochrome C carbene transferase 在细胞色素C卡宾转移酶中发现的催化铁卡宾中间体

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2018-06-26

110

OAAI

Lewis, Russell D.; Garcia-Borras, Marc; Chalkley, Matthew J.; Buller, Andrew R.; Houk, K. N.; Kan, S. B. Jennifer; Arnold, Frances H.

Diverse Engineered Heme Proteins Enable Stereodivergent Cyclopropanation of Unactivated Alkenes

ACS CENTRAL SCIENCE

IF10.4

2018-02-21

118

OAAI

Knight, Anders M.; Kan, S. B. Jennifer; Lewis, Russell D.; Brandenberg, Oliver F.; Chen, Kai; Arnold, Frances H.

Highly Stereoselective Biocatalytic Synthesis of Key Cyclopropane Intermediate to Ticagrelor

ACS CATALYSIS

IF13.1

2016-10-19

OAAI

Hernandez, Kari E.; Renata, Hans; Lewis, Russell D.; Kan, S. B. Jennifer; Zhang, Chen; Forte, Jared; Rozzell, David; McIntosh, John A.; Arnold, Frances H.

Identification of Mechanism-Based Inactivation in P450-Catalyzed Cyclopropanation Facilitates Engineering of Improved Enzymes

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

IF15.6

2016-09-14

OAAI

Renata, Hans; Lewis, Russell D.; Sweredoski, Michael J.; Moradian, Annie; Hess, Sonja; Wang, Z. Jane; Arnold, Frances H.

研究方向