Kensuke Osada - Publications, H-index & Citations

Kensuke Osada

national institutes for quantum sciences and technology (qst)

52H指数

177论文数

8.4K被引数

收录论文 72

发表时间

Collagen Signaling via DDR1 Exacerbates Barriers to Macromolecular Drug Delivery in a 3D Model of Pancreatic Cancer Fibrosis 通过DDR1介导的胶原信号加剧了在胰腺癌纤维化3D模型中高分子药物递送屏障

Small

IF12.1

2025-10-31

OAAI

Mayu Ohira; Moe Kitamura; Hiroyo Iwasaki; Haruko Ohta-Okano; Hiyori Tsujii; Reika Nakamura; Takuya Nakazawa; Akihiro Nishiguchi; Masaya Yamamoto; Kensuke Osada; Shinichi Toyooka; Horacio Cabral; Atsushi Masamune; Mitsunobu R. Kano; Hiroyoshi Y. Tanaka

Quantification of Oxygenation and Oxygen Consumption Rates in the Mouse Brain Based on Tissue Oxygen Level-Dependent (TOLD) MRI 基于组织氧水平依赖性（TOLD）MRI对小鼠脑部氧合作用和氧耗速率的量化

NMR in Biomedicine

IF2.7

2025-07-22

OAAI

Raj Kumar Parajuli; Hiromi Sano; Megumi Ueno; Shan Gao; Saaya Suzuki; Akira Sumiyoshi; Kensuke Osada; Takayuki Obata; Ichio Aoki; Ken-ichiro Matsumoto

An Electron Paramagnetic Resonance Study of the Superoxide-Scavenging and Redox-Modulating Effects of Lecithinized Superoxide Dismutase in the Bloodstream 电子顺磁共振研究：卵磷脂化超氧化物歧化酶在血液中的超氧化物清除和氧化还原调控作用

MOLECULES

IF4.6

2025-04-23

OAAI

Lazarova, Dessislava; Getsov, Plamen; Bakalova, Rumiana; Nikolova, Biliana; Semkova, Severina; Zhelev, Zhivko; Qiao, Zhiwei; Ishikawa, Tomohiro; Fukuda, Koichiro; Osada, Kensuke; Mileva, Milka; Mizushima, Tohru

Methemoglobin-Encapsulating Liposome: A Low-Risk Intravascular Contrast Agent for Magnetic Resonance Imaging 携载高铁血红蛋白的脂质体：一种低风险的磁共振成像血管内造影剂

ACS APPLIED BIO MATERIALS

IF4.7

2025-04-07

PREAI

Taguchi, K; Sumiyoshi, A; Suzuki, Y; Ozawa, Y; Iiyama, M; Gao, S; Sakai, H; Osada, K; Matsumoto, K; Aoki, I

Effects of 2 Gy x 20 fractionated X-ray irradiation on the redox metabolic activity in mouse colorectum tissue

FREE RADICAL BIOLOGY AND MEDICINE

IF8.2

2024-11-01

PREAI

Ueno, Megumi; Parajuli, Raj Kumar; Sano, Hiromi; Gao, Shan; Matsumoto, Ken-ichiro; Osada, Kensuke; Obata, Takayuki; Aoki, Ichio; Sumiyoshi, Akira

Quantification of Poly(ethylene glycol) Crowding on Nanodiamonds toward Quantum Biosensor for Improved Prevention Effects on Protein Adsorption and Lung Accumulation

LANGMUIR

IF3.9

2024-04-22

PREAI

Rikiyama, Kazuaki; Maehara, Nanami; Abe, Hiroshi; Nishimura, Yushi; Yukawa, Hiroshi; Kaminaga, Kiichi; Igarashi, Ryuji; Osada, Kensuke

Block Copolymer-Stabilized Metal-Organic Framework Hybrids Loading Pd Nanoparticles Enable Tumor Remission Through Near-Infrared Photothermal Therapy

ADVANCED NANOBIOMED RESEARCH

IF4.4

2023-12-03

OAAI

Li, Shang-Wei; Hsieh, Ming-Feng; Hong, Taehun; Chen, Pengwen; Osada, Kensuke; Liu, Xueying; Aoki, Ichio; Yu, Jiashing; Wu, Kevin C. -W.; Cabral, Horacio

Self-Folding Macromolecular Drug Carrier for Cancer Imaging and Therapy 用于癌症成像和治疗的自折叠大分子药物载体

ADVANCED SCIENCE

IF14.1

2023-11-29

OAAI

Gao, Shan; Miura, Yutaka; Sumiyoshi, Akira; Ohno, Satoshi; Ogata, Keisuke; Nomoto, Takahiro; Matsui, Makoto; Honda, Yuto; Suzuki, Minoru; Iiyama, Megumi; Osada, Kensuke; Aoki, Ichio; Nishiyama, Nobuhiro

An Approach for Estimating Oxygen Consumption in Tissues Based on TOLD MRI Signal

FREE RADICAL BIOLOGY AND MEDICINE

IF8.2

2023-11-01

PREAI

Matsumoto, Ken-ichiro; Parajuli, Raj Kumar; Sano, Hiromi; Ueno, Megumi; Sumiyoshi, Akira; Osada, Kensuke; Obata, Takayuki; Aoki, Ichio

Bridging mRNA and Polycation Using RNA Oligonucleotide Derivatives Improves the Robustness of Polyplex Micelles for Efficient mRNA Delivery 使用RNA寡核苷酸衍生物桥接mRNA和聚阳离子提高了多聚复合物胶束的稳健性，可有效传递mRNA

ADVANCED HEALTHCARE MATERIALS

IF9.6

2021-12-23

PREAI

Yoshinaga, Naoto; Uchida, Satoshi; Dirisala, Anjaneyulu; Naito, Mitsuru; Koji, Kyoko; Osada, Kensuke; Cabral, Horacio; Kataoka, Kazunori

PEGylation of mRNA by Hybridization of Complementary PEG-RNA Oligonucleotides Stabilizes mRNA without Using Cationic Materials

PHARMACEUTICS

IF5.5

2021-05-27

OAAI

Yoshinaga, Naoto; Naito, Mitsuru; Tachihara, Yoshihiro; Boonstra, Eger; Osada, Kensuke; Cabral, Horacio; Uchida, Satoshi

Size-controlled bimodal in vivo nanoprobes as near-infrared phosphors and positive contrast agents for magnetic resonance imaging 尺寸控制的双峰体内纳米探针作为近红外磷光体和阳性造影剂用于磁共振成像

SCIENCE AND TECHNOLOGY OF ADVANCED MATERIALS

IF6.9

2021-03-10

OAAI

Okubo, Kyohei; Takeda, Ryuta; Murayama, Shuhei; Umezawa, Masakazu; Kamimura, Masao; Osada, Kensuke; Aoki, Ichio; Soga, Kohei

mRNA loading into ATP-responsive polyplex micelles with optimal density of phenylboronate ester crosslinking to balance robustness in the biological milieu and intracellular translational efficiency mRNA加载到具有最佳苯硼酸酯交联密度的ATP响应性多聚复合物胶束中，以平衡生物环境中的稳健性和细胞内翻译效率

JOURNAL OF CONTROLLED RELEASE

IF11.5

2021-02-01

OAAI

Yoshinaga, Naoto; Uchida, Satoshi; Dirisala, Anjaneyulu; Naito, Mitsuru; Osada, Kensuke; Cabral, Horacio; Kataoka, Kazunori

Bundling of mRNA strands inside polyion complexes improves mRNA delivery efficiency in vitro and in vivo

BIOMATERIALS

IF12.9

2020-12-01

PREAI

Koji, Kyoko; Yoshinaga, Naoto; Mochida, Yuki; Hong, Taehun; Miyazaki, Takuya; Kataoka, Kazunori; Osada, Kensuke; Cabral, Horacio; Uchida, Satoshi

Transient stealth coating of liver sinusoidal wall by anchoring two-armed PEG for retargeting nanomedicines 通过锚定双臂PEG对肝正弦壁进行瞬态隐身涂层，以重新靶向纳米药物

SCIENCE ADVANCES

IF12.5

2020-06-26

OAAI

Dirisala, Anjaneyulu; Uchida, Satoshi; Toh, Kazuko; Li, Junjie; Osawa, Shigehito; Tockary, Theofilus A.; Liu, Xueying; Abbasi, Saed; Hayashi, Kotaro; Mochida, Yuki; Fukushima, Shigeto; Kinoh, Hiroaki; Osada, Kensuke; Kataoka, Kazunori

Single-Stranded DNA-Packaged Polyplex Micelle as Adeno-Associated-Virus-Inspired Compact Vector to Systemically Target Stroma-Rich Pancreatic Cancer

ACS NANO

IF16

2019-10-24

PREAI

Tockary, Theofilus A.; Foo, Wanling; Dirisala, Anjaneyulu; Chen, Qixian; Uchida, Satoshi; Osawa, Shigehito; Mochida, Yuki; Liu, Xueying; Kinoh, Hiroaki; Cabral, Horacio; Osada, Kensuke; Kataoka, Kazunori

In vivo rendezvous of small nucleic acid drugs with charge-matched block catiomers to target cancers 小核酸药物与电荷匹配的嵌段异构体的体内交会，以靶向癌症

NATURE COMMUNICATIONS

IF15.7

2019-04-24

OAAI

Watanabe, Sumiyo; Hayashi, Kotaro; Toh, Kazuko; Kim, Hyun Jin; Liu, Xueying; Chaya, Hiroyuki; Fukushima, Shigeto; Katsushima, Keisuke; Kondo, Yutaka; Uchida, Satoshi; Ogura, Satomi; Nomoto, Takahiro; Takemoto, Hiroyasu; Cabral, Horacio; Kinoh, Hiroaki; Tanaka, Hiroyoshi Y.; Kano, Mitsunobu R.; Matsumoto, Yu; Fukuhara, Hiroshi; Uchida, Shunya; Nangaku, Masaomi; Osada, Kensuke; Nishiyama, Nobuhiro; Miyata, Kanjiro; Kataoka, Kazunori

Induced packaging of mRNA into polyplex micelles by regulated hybridization with a small number of cholesteryl RNA oligonucleotides directed enhanced in vivo transfection 通过与少量胆固醇RNA寡核苷酸的调节杂交诱导mRNA包装到多聚复合物胶束中，从而增强了体内转染

BIOMATERIALS

IF12.9

2019-03-01

OAAI

Yoshinaga, Naoto; Uchida, Satoshi; Naito, Mitsuru; Osada, Kensuke; Cabral, Horacio; Kataoka, Kazunori

Polyplex Micelles with Phenylboronate/Gluconamide Cross-Linking in the Core Exerting Promoted Gene Transfection through Spatiotemporal Responsivity to Intracellular pH and ATP Concentration

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

IF15.6

2017-12-14

PREAI

Yoshinaga, Naoto; Ishii, Takehiko; Naito, Mitsuru; Endo, Taisuke; Uchida, Satoshi; Cabral, Horacio; Osada, Kensuke; Kataoka, Kazunori

Glycaemic control boosts glucosylated nanocarrier crossing the BBB into the brain

NATURE COMMUNICATIONS

IF15.7

2017-10-17

202

OAAI

Anraku, Y.; Kuwahara, H.; Fukusato, Y.; Mizoguchi, A.; Ishii, T.; Nitta, K.; Matsumoto, Y.; Toh, K.; Miyata, K.; Uchida, S.; Nishina, K.; Osada, K.; Itaka, K.; Nishiyama, N.; Mizusawa, H.; Yamasoba, T.; Yokota, T.; Kataoka, K.

研究方向