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G

Gerhard Grüber

nanyang technological university

44H指数
336论文数
7.4K被引数
收录论文 143
发表时间
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The Mycobacterium abscessus cytochrome bcc:aa3 oxidase structure paves the way for an agent targeting subunit QcrB分枝杆菌属脓肿分枝杆菌（Mycobacterium abscessus）的细胞色素bcc:aa3氧化酶结构为靶向亚基QcrB的药物研发奠定了基础。
errNature Communications
IF15.7
err2026-04-03
err0
errOAAI
errVikneswaran Mathiyazakan; Emilia Xin Yi Tan; Garrett Moraski; Sandip Basak; Wuan-Geok Saw; Kevin Pethe; Gerhard Grüber
err分享
err收藏
A Series of Pyrazolo-Quinazoline Amines Inhibits the Cytochrome bd Oxidase in Mycobacterium tuberculosis
errJOURNAL OF MEDICINAL CHEMISTRY
IF6.8
err2026-01-01
err0
PREAI
errSingh, Samsher; Ng, Pearly Shuyi; Lakshmanan, Umayal; Mathiyazakan, Vikneswaran; Wiggins, Thomas; Lee, Bei Shi; Ang, Shi Hua; Lin Sim, Sandra Wei; Santos, May Delos; Moraski, Garrett; Miller, Marvin; Berney, Michael; Gruber, Gerhard; Pethe, Kevin
err分享
err收藏
The Inlet; Outlet; and New Ratchet Element for Proton Transfer of the Acinetobacter baumannii F-ATP Synthase and Their Critical Role for Viability入孔、出孔以及铜绿假单胞菌F-ATP合酶质子转移的新棘爪元件及其对存活的关键作用
errACS Infectious Diseases
IF3.8
err2025-11-27
err0
PREAI
errKhoa Cong Minh Le; Vandana Grover; Amaravadhi Harikishore; Tuck Choy Fong; Jan Kazimierz Marzinek; Alexander Krah; Dang Hai Pham; Peter John Bond; Gerhard Grüber
err分享
err收藏
Treatment outcomes in Mycobacterium abscessus pulmonary disease: A systematic review
errANNALS ACADEMY OF MEDICINE SINGAPORE
IF2
err2025-11-01
err1
PREAI
errLim, Albert Yick Hou; Pethe, Kevin; Khoong, Cheryl Hui Ling; Dedon, Peter; Gruber, Gerhard
err分享
err收藏
The N-Terminal Extension of the Mycobacterium avium Rel Protein Is a Dual Regulator of the Bifunctional Enzyme and Represents a Novel Target分枝杆菌(Mycobacterium avium)Rel蛋白的N端延伸是双功能酶的双重调节因子，并代表一个新型靶点
errAntibiotics 2025, Vol. 14, Page 964
IF0
err2025-09-26
err0
errOAAI
errTuck Choy Fong; Priya Ragunathan; Reema Alag; Carlos Silvester; Svarika Sonthalia; Vikneswaran Mathiyazakan; Vandana Grover; Gerhard Grüber
err分享
err收藏
Whole-Cell Study Unveils Critical Mechanistic Elements, Regulatory Elements, and Inhibitor Targets of the Mycobacterium abscessus Cytochrome bd Oxidase全细胞研究揭示了脓肿分枝杆菌细胞色素bd氧化酶的关键机制元件、调控元件和抑制剂靶点
errACS INFECTIOUS DISEASES
IF3.8
err2025-04-08
err0
PREAI
errMathiyazakan, V; Kathalingam, SS; Pok, WN; Sorayah, R; Pethe, K; Grüber, G
err分享
err收藏
Mycobacterium tuberculosis F-ATP Synthase Inhibitors and Targets
errANTIBIOTICS-BASEL
IF4.6
err2024-12-03
err0
errOAAI
errHarikishore, Amaravadhi; Gruber, Gerhard
err分享
err收藏
SQ31f is a potent non-tuberculous mycobacteria antibiotic by specifically targeting the mycobacterial F-ATP synthase
errJOURNAL OF ANTIMICROBIAL CHEMOTHERAPY
IF3.6
err2024-11-05
err1
PREAI
errRagunathan, Priya; Sae-Lao, Patcharaporn; Harikishore, Amaravadhi; Daher, Wassim; Roquet-Baneres, Francoise; Kremer, Laurent; Bates, Roderick W.; Gruber, Gerhard
err分享
err收藏
Cryo-EM reveals transition states of the Acinetobacter baumannii F1-ATPase rotary subunits γ and ε, unveiling novel compound targets
errFASEB JOURNAL
IF4.2
err2024-10-28
err0
errOAAI
errLe, Khoa Cong Minh; Wong, Chui Fann; Mueller, Volker; Grueber, Gerhard
err分享
err收藏
Isolation, Purification and Cryo-Electron Microscopy Structure determination of the Mycobacterium tuberculosis Cytochrome bcc:aa3 Supercomplex
errBIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS
IF2.7
err2024-09-01
err0
PREAI
errMathiyazakan, Vikneswaran; Wong, Chui-Fann; Harikishore, Amaravadhi; Pethe, Kevin; Gruber, Gerhard
err分享
err收藏
Highly potent anti-NTM inhibitors targeting the oxidative phosphorylation pathway of a broad spectrum of nontuberculous mycobacterial pathogens
errBIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS
IF2.7
err2024-09-01
err0
PREAI
errRagunathan, Priya; Sae-Lao, Patcharaporn; Harikishore, Amaravadhi; Krah, Alexander; Dick, Thomas; Kremer, Laurent; Bates, Roderick W.; Gruber, Gerhard
err分享
err收藏
Targeting energy of life for eradication of antimicrobial resistant pathogens
errBIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS
IF2.7
err2024-09-01
err0
PREAI
errGruber, Gerhard
err分享
err收藏
Atomic insights into the F-ATP synthase e-induced ATP hydrolysis inhibition of the pathogen Acinetobacter baumannii
errBIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS
IF2.7
err2024-09-01
err0
PREAI
errLe, Khoa C. M.; Geok, Saw W.; Kwek, Jes H. M.; Wong, Chui F.; Fong, Tuck C.; Mueller, Volker; Gruber, Gerhard
err分享
err收藏
Barnacle cement protein as an efficient bioinspired corrosion inhibitor
errCOMMUNICATIONS MATERIALS
IF9.6
err2024-02-23
err2
errOAAI
errBui, My Hanh; Hiew, Shu Hui; Salim, Teddy; Saw, Wan Geok; Webster, Richard D.; Gruber, Gerhard; Mu, Yuguang; Miserez, Ali
err分享
err收藏
High efficacy of the F-ATP synthase inhibitor TBAJ-5307 nontuberculous in vitro and in vivo
errJOURNAL OF BIOLOGICAL CHEMISTRY
IF3.9
err2024-02-01
err4
errOAAI
errRagunathan, Priya; Sae-Lao, Patcharaporn; Hamela, Claire; Alcaraz, Mattheo; Krah, Alexander; Poh, Wee Han; Pee, Carmen Jia Ern; Lim, Albert Yick Hou; Rice, Scott A.; Pethe, Kevin; Bond, Peter J.; Dick, Thomas; Kremer, Laurent; Bates, Roderick W.; Grueber, Gerhard
err分享
err收藏
GaMF1.39's antibiotic efficacy and its enhanced antitubercular activity in combination with clofazimine, Telacebec, ND-011992, or TBAJ-876
errMICROBIOLOGY SPECTRUM
IF3.8
err2023-12-12
err3
errOAAI
errRagunathan, Priya; Shuyi Ng, Pearly; Singh, Samsher; Poh, Wee Han; Litty, Dennis; Kalia, Nitin Pal; Larsson, Simon; Harikishore, Amaravadhi; Rice, Scott A.; Ingham, Philip W.; Mueller, Volker; Moraski, Garrett; Miller, Marvin J.; Dick, Thomas; Pethe, Kevin; Gruber, Gerhard
err分享
err收藏
Novel targets and inhibitors of the Mycobacterium tuberculosis cytochrome bd oxidase to foster anti-tuberculosis drug discovery
errEXPERT OPINION ON DRUG DISCOVERY
IF4.9
err2023-06-18
err12
errOAAI
errHarikishore, Amaravadhi; Mathiyazakan, Vikneswaran; Pethe, Kevin; Gruber, Gerhard
err分享
err收藏
Cryo-Electron Microscopy Structure of the Mycobacterium tuberculosis Cytochrome bcc:aa3 Supercomplex and a Novel Inhibitor Targeting Subunit Cytochrome cI
errANTIMICROBIAL AGENTS AND CHEMOTHERAPY
IF4.5
err2023-06-15
err4
errOAAI
errMathiyazakan, Vikneswaran; Wong, Chui-Fann; Harikishore, Amaravadhi; Pethe, Kevin; Gruber, Gerhard
err分享
err收藏
Atomic insights of an up and down conformation of the Acinetobacter baumannii F1-ATPase subunit e and deciphering the residues critical for ATP hydrolysis inhibition and ATP synthesis
errFASEB JOURNAL
IF4.2
err2023-06-15
err4
PREAI
errSaw, Wuan-Geok; Le, Khoa Cong Minh; Shin, Joon; Kwek, Jes Hui Min; Wong, Chui Fann; Ragunathan, Priya; Fong, Tuck Choy; Mueller, Volker; Grueber, Gerhard
err分享
err收藏
The FGFR inhibitor PD173074 binds to the C-terminus of oncofetal HMGA2 and modulates its DNA-binding and transcriptional activation functions
errFEBS LETTERS
IF3
err2023-06-08
err0
PREAI
errAhmed, Syed Moiz; Ragunathan, Priya; Shin, Joon; Peter, Sabrina; Kleissle, Sabrina; Neuenschwander, Martin; Schaefer, Reinhold; Kries, Jens Peter V.; Grueber, Gerhard; Droge, Peter
err分享
err收藏

研究方向

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